| Formulary Chapter 3: Respiratory system - Full Chapter
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| Chapter Links... |
 NICE CG115: Chronic obstructive pulmonary disease in over 16s: diagnosis and management |
| NICE TA10: Guidance on the use of inhaler systems (devices) in children under the age of 5 years with chronic asthma |
| NICE TA138: Inhaled corticosteroids for the treatment of chronic asthma in adults and in children aged 12 years and over |
| NICE TA38: Inhaler devices for routine treatment of chronic asthma in older children (aged 5–15 years) |
 BCICB Asthma Treatment Guidelines - Adolescents 12-17 years old |
| BCICB Asthma Treatment Guidelines - Adults 18+ |
| BCICB Asthma Treatment Guidelines For Children Under 12 |
| BCICB COPD Inhaler Treatment Guidelines |
| BCICB Difficult Asthma Referral Pathway - Adults 18+ |
| Greener Inhaler Guide Switching Information |
| How to improve respiratory control in asthma and COPD |
| COVID-19: information for the respiratory community |
| Details... |
| 03.01 |
Bronchodilators |
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| 03.01 |
Asthma |
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| 03.01 |
Chronic obstructive pulmonary disease |
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| 03.01 |
Croup |
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| 03.01.01 |
Adrenoceptor agonists |
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| 03.01.01.01 |
Selective Beta2 agonists |
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Salbutamol
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Formulary
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BRANDS/FORMULATION
- Easyhaler
- Ventolin Accuhaler
- Salamol
- Salamol Easi-Breathe
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
How to use an Accuhaler inhaler
How to use an Easyhaler Inhaler
How to use an Easi-Breathe Inhaler
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Salbutamol
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Formulary
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- Salbutamol IV
- Ventolin Solution for Infusion
- Ventolin Solution for Injection
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Formoterol Fumarate (Oxis Turbohaler®)
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Formulary
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Salbutamol (Nebuliser Liquid ® )
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Formulary
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Green-Nebuliser Liquid
 Amber Recommended- Nebuliser Liquid in Paediatrics
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MHRA Alert: Nebulised asthma rescue therapy in children
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Terbutaline
(Nebuliser Liquid)
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Formulary
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How to use a Turbohaler Inhaler
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Terbutaline (Bricanyl®)
(Inhaler)
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Formulary
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How to use a Turbohaler Inhaler
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| 03.01.01.01 |
Short-acting beta2 agonists |
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| 03.01.01.01 |
Long-acting beta2 agonists |
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| 03.01.01.02 |
Other adrenoceptor agonists |
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Ephedrine Hydrochloride
(Solution for injections)
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Formulary
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| 03.01.02 |
Antimuscarinic bronchodilators |
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Tiotropium (Spiriva Respimat®)
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Formulary
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How to use a Respimat Inhaler
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Aclidinium (Eklira Genuair®)
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Formulary
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For COPD only
How to use a Genuair Inhaler
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Ipratropium bromide
(Nebuliser Liquid)
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Formulary
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Umeclidinium (Incruse® Ellipta®)
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Formulary
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How to use an Ellipta Inhaler
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| 03.01.02 |
Short Acting Anti-muscarinic Bronchodilators |
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| 03.01.02 |
Long Acting Anti-muscarinic Bronchodilators |
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| 03.01.03 |
Theophylline |
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Theophylline (Uniphyllin Continus )
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Formulary
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Aminophylline IV
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Formulary
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UKMI Q&A: Switching between aminophylline and theophylline in adults
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| 03.01.04 |
Compound bronchodilator preparations |
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Aclidinium & formoterol inhaler (Duaklir Genuair®)
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Formulary
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How to use a Genuair Inhaler
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Glycopyrronium/formoterol (Bevespi Aerosphere®)
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Formulary
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Tiotropium & Olodaterol (Spiolto® Respimat®)
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Formulary
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How to use a Respimat Inhaler
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Umeclidinium & vilanterol (Anoro Ellipta®)
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Formulary
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How to use an Ellipta Inhaler
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| 03.01.05 |
Peak flow meters, inhaler devices and nebulisers |
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| 03.01.05 |
Peak flow meters |
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Low range peak flow meter
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Formulary
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BRANDS
- Rossmax Peak Flow Meter
- Easy Peak Flow Meter Low Range
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Standard range peak flow meter
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Formulary
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BRANDS
- Easy Peak Flow Meter
- Rossmax Peak Flow Meter
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| 03.01.05 |
Drug delivery devices |
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AeroChamber Plus®
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Formulary
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Drug Delivery Device
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Formulary
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- Aerochamber Plus
- Aerochamber Plus Flow-vu Anti-static
- Aerochamber Plus Flow-vu Anti-static With Adult Large Mask
- Aerochamber Plus Flow-vu Anti-static With Adult Small Mask
- Aerochamber Plus Flow-vu Anti-static With Medium Mask Child 1-5 Years
- Aerochamber Plus Flow-vu Anti-static With Small Mask Infant 0-18 Months
- Aerochamber Plus Flow-vu Anti-static Youth 5
- Aerochamber Plus With Adult Mask
- Aerochamber Plus With Child Mask
- Aerochamber Plus With Infant Mask
- Volumatic
- Volumatic With Paediatric Mask
- Zerostat Vt Spacer
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How to use a Metered Dose Inhaler with a Large Volume Spacer
HOw to use a Meterted Dose Inhaler with a Small Spacer
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| 03.01.05 |
Nebulisers |
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| 03.01.05 |
Nebuliser Diluent |
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Sodium Chloride
(nebulised)
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Formulary
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| 03.02 |
Corticosteroids |
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Beclometasone and formoterol (Fostair®)
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Formulary
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Licensed for both asthma and COPD
Asthma - use lowest effective dose. Consider step down at each review. Consider switch if appropriate
Alternative to Seretide Evohaler / Seretide 250 Accuhaler
Note: when switching patients already using Beclometasone 250mcg CFC inhaler (e.g. Clenil), Fostair 100/6 can be prescribed and dose adjusted according to response
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Beclometasone and formoterol (Fostair® NEXThaler®)
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Formulary
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How to use a NEXThaler Inhaler
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Beclometasone Dipropionate (Clenil Modulite®)
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Formulary
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May 2020 - see Clenil® Modulite® 100mcg (beclometasone): release of batch specific variation
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Budesonide
(Nebuliser Liquid)
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Formulary
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Budesonide
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Formulary
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- Dry powder Inhaler
- Easyhaler
- Prescribe by brand
How to use a Turbohaler Inhaler
How to use an Easyhaler Inhaler
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Budesonide (Easyhaler® )
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Formulary
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How to use an Easyhaler Inhaler
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Budesonide (Pulmicort Respules®)
(Nebuliser Liquid)
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Formulary
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Budesonide (Pulmicort Turbohaler®)
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Formulary
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How to use a Turbohaler Inhaler
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Budesonide and Formoterol (Fobumix Easyhaler®)
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Formulary
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How to use an Easyhaler Inhaler
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Budesonide and Formoterol 100/6 (Symbicort Turbohaler®)
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Formulary
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- For treatment of asthma only
- Use lowest effective dose. Consider step down at each review.
- Prescribe by brand to ensure patient receives the device they are used to.
How to use a Turbohaler Inhaler
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Budesonide and Formoterol 200/6 (Symbicort Turbohaler®)
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Formulary
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For Asthma, maintenance and reliever therapy in adults and adolescents (12 years and older) with mild asthma
How to use a Turbohaler Inhaler
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Fluticasone
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Formulary
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- Flixonase Nasal Drops
- Flixotide Nebuliser Liquid
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Fluticasone and salmeterol (Seretide®)
(Inhaler)
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Formulary
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For paediatric use ONLY (i.e. up to 18 years of age)
- Seretide Evohaler- 50mg and 125mg only .
- Should be prescribed by the intended brand to ensure patients are maintained on the formulation they are used to.
How to use an Accuhaler Inhaler
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Fluticasone furoate & vilanterol (Relvar Ellipta®)
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Formulary
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How to use an Ellipta Inhaler
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Fluticasone Nasal Spray
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Formulary
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BRANDS
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Fluticasone Nasal Spray (Avamys®)
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Formulary
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Fluticasone propionate (Flixotide®)
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Formulary
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How to use an Accuhaler Inhaler
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Mometasone
(Spray)
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Formulary
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Prednisolone
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Formulary
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 UKMI Q&A: Is there any evidence to support the use of enteric coated (EC) over uncoated prednisolone tablets?
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| 03.02.01 |
Inhaled Corticosteroids |
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| 03.02.02 |
Combination products (ICS+LABA) for asthma |
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| 03.02.02 |
Low dose |
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| 03.02.02 |
Moderate dose |
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| 03.02.02 |
High dose |
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| 03.02.03 |
Combination products (ICS+LABA) for COPD |
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| 03.02.03 |
Triple Therapy products for COPD |
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Beclometasone/formoterol/glycopyrronium (Trimbow 87/5/9 ®)
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Formulary
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Trimbow 87/5/9 is licensed for Moderate-to-severe chronic obstructive pulmonary disease and Asthma maintenance therapy
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How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Beclometasone/formoterol/glycopyrronium
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Formulary
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How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Beclometasone/formoterol/glycopyrronium (Trimbow 172/5/9 ®)
|
Formulary
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Note:
-Two strengths of Trimbow available
* Trimbow 172/5/9
* Trimbow 87/5/9
-Trimbow 172/5/9 is licensed for Asthma maintenance therapy only
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How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
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Beclometasone/formoterol/glycopyrronium (Trimbow NEXThaler®)
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Formulary
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How to use a NEXThaler Inhaler
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Fluticasone/vilanterol/Umeclidinium (Trelegy Ellipta®)
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Formulary
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How to use an Ellipta Inhaler
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| 03.03 |
Cromoglicate, related therapy and leukotriene receptor antagonists |
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| 03.03.01 |
Cromoglicate and related therapy |
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| 03.03.01 |
Related therapy |
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| 03.03.02 |
Leukotriene receptor antagonists |
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Montelukast
(Oral presentations)
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Formulary
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Use in line with recommendations in BTS-SIGN asthma guideline
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| 03.03.03 |
Phosphodiesterase type-4 inhibitors |
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Roflumilast (Daxas®)
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Formulary
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In line with NICE
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NICE TA461: Roflumilast for treating chronic obstructive pulmonary disease
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| 03.04 |
Antihistamines, hyposensitisation, and allergic emergencies |
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Bee and Wasp Allergen Extracts (Pharmalgen®)
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Formulary
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NICE TA246: Pharmalgen for the treatment of bee and wasp venom allergy
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Grass pollen extract (Grazax®)
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Formulary
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Grass pollen extract (Pollinex ®)
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Formulary
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House dust mite extract (Acarizax®)
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Formulary
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House dust mite extract (Mitizax®)
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Formulary
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Tree pollen extract (Pollinex Trees ®)
(Form unstated )
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Formulary
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Tree pollen extract (Pollinex trees ®)
(Suspension for Injection)
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Formulary
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| 03.04.01 |
Antihistamines |
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| 03.04.01 |
Non-sedating antihistamines |
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Loratadine
(Tablets, Solution )
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Formulary
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OTC preparation suitable for self-care/purchase if appropriate
|
Conditions for which over the counter items should not routinely be prescribed in primary care: Guidance for CCGs
|
Cetirizine Hydrochloride
(Oral presentations)
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Formulary
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OTC preparation suitable for self-care/purchase if appropriate
- Capsules
- Oral Solution- Green for children and those unable to swallow
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Conditions for which over the counter items should not routinely be prescribed in primary care: Guidance for CCGs
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Fexofenadine (Telfast®)
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Formulary
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Fexofenadine
|
Formulary
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| 03.04.01 |
Sedating antihistamines |
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Chlorphenamine
(Oral presentations)
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Formulary
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OTC preparation suitable for self-care/purchase if appropriate
- Oral Solution- for children and those unable to swallow
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Chlorphenamine maleate
(solution for Injection)
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Formulary
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Hydroxyzine
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Formulary
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Promethazine
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Formulary
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OTC preparation suitable for self-care/purchase if appropriate
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| 03.04.02 |
Allergen Immunotherapy |
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Bee venom extract
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Formulary
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Benralizumab
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Formulary
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NICE TA565: Benralizumab for treating severe eosinophilic asthma
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Grass and Tree Pollen Extract (Pollinex®)
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 Restricted
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For hospital use only
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Wasp venom extract
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Formulary
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| 03.04.02 |
Omalizumab |
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Omalizumab (Xolair®)
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Restricted
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For specialist use only in line with NICE TAs
Commissioned by NHSE
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NICE TA 339: Omalizumab for previously treated chronic spontaneous urticaria
TA278 Asthma (severe, persistent, patients aged 6+,adults) - omalizumab (revised TA133, TA201)
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| 03.04.03 |
Allergic emergencies |
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| 03.04.03 |
Anaphylaxis |
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Adrenaline / epinephrine (EpiPen®)
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Formulary
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Adrenaline / Epinephrine (Jext®)
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Formulary
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Adrenaline / Epinephrine (Emerade®)
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Formulary
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There has been a patient-level recall of Emerade 500 micrograms pens. This follows earlier recalls for Emerade 150 and 300 microgram pens. (18 May 2020)
Supplies of Emerade will therefore no longer be available in the UK until technical issues with the pen are resolved.
MHRA - Advice for patients with an Emerade 500 microgram auto-injector letter
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Adrenaline / Epinephrine 1 in 1,000 (Minijet ® Adrenaline 1 in 1000)
|
Formulary
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Adrenaline / Epinephrine 1 in 10,000 (Minijet ® Adrenaline 1 in 10000)
|
Formulary
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| 03.04.03 |
Angioedema |
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Conestat Alfa (Ruconest®)
|
Formulary
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Hospital only- NHSE Commissioned
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Dupilumab (Dupixent®)
(Subcutaneous injection)
|
Formulary
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NICE TA751: Dupilumab for treating severe asthma with type 2 inflammation
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Icatibant (Firazyr®)
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Restricted
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Hospital only- NHSE Commissioned
|
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Lanadelumab (Takhzyro®)
|
Formulary
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In line with NICE
Highly specialist allergy centre- NHSE commissioned
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NICE TA606: Lanadelumab for preventing recurrent attacks of hereditary angioedema
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C1- esterase Inhibitor (Berinert®)
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Restricted
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Berotralstat (Orladeyo® )
|
Restricted
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Use in line with NICE TA
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NICE TA738:Berotralstat for preventing recurrent attacks of hereditary angioedema
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C1- esterase Inhibitor (Cinryze®)
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Restricted
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| 03.04.03 |
Intramuscular adrenaline (epinephrine) |
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| 03.04.03 |
Intravenous adrenaline (epinephrine) |
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| 03.04.03 |
Self-administration of adrenaline (epinephrine) |
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| 03.05 |
Respiratory stimulants and pulmonary surfactants |
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| 03.05.01 |
Respiratory stimulants |
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Doxapram
|
Formulary
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Doxapram (Dopram®)
|
Formulary
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Caffeine citrate
|
 Unlicensed
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| 03.05.02 |
Pulmonary surfactants |
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Poractant Alfa (Curosurf®)
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Restricted
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For Hospital use only
Commissioned by NHSE
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| 03.06 |
Oxygen |
|
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Oxygen
|
Formulary
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| 03.06 |
Long-term oxygen therapy |
|
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Oxygen
|
Formulary
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| 03.06 |
Short burst oxygen therpary |
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| 03.06 |
Ambulatory oxygen therapy |
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| 03.06 |
Oxygen therapy equipment |
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| 03.06 |
Arrangements for supplying oxygen |
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| 03.07 |
Mucolytics |
|
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Carbocisteine
|
Formulary
|
Prescribe as 375 mg caps. Avoid prescribing 750 mg caps
|
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Acetylcysteine
(SOLUTION FOR INFUSION)
|
Formulary
|
Brand: Parvolex
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Acetylcysteine (oral presentations)
|
Formulary
|
- Brands (NACSYS and Nexus)
- See brands -Prescribe as Acetylcyteine S/f tabs
|
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Acetylcysteine effervescent tablet (Aceteff® )
|
Formulary
|
Acetylcysteine SF effervescent tabs most cost effective
|
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Ivacaftor (Kalydeco®)
(Tablet)
|
Formulary
|
In line with NICE
|
Clinical Commissioning Policy: Ivacaftor for Cystic Fibrosis (named mutations)
|
Lumacaftor with ivacaftor (Orkambi®)
(Tablets)
|
Formulary
|
In line with NICE
|
NICE TA398: Lumacaftor-ivacaftor for treating cystic fibrosis homozygous for the F508del mutation
|
Mannitol (Bronchitol®)
(inhalation powder)
|
Restricted
|
Hospital only
Commissioned by NHSE
|
TA266: Mannitol dry powder for inhalation for treating cystic fibrosis
|
Sodium chloride 0.9%
|
Formulary
|
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Sodium Chloride 7%
|
Formulary
|
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N-Acetylcysteine nebulised
|
Restricted
|
Hospital only
|
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|
| 03.07 |
Dornase alfa |
|
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Dornase Alfa (Pulmozyme®)
|
Formulary
|
Commissioned by NHSE for Cystic Fibrosis only
|
|
|
| 03.07 |
Hypertonic Sodium Chloride |
|
|
Hypertonic sodium chloride
|
Formulary
|
VIALS
AMPOULES
- Bronchlear 3%
- Mucoclear 3%
- Nebusal 7%
- Pulmoclear 3%
- Pulmoclear 7%
- Resp-ease 3%
- Resp-ease 7%
- Respi-clear 7%
- Salineb 7%
|
|
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Sodium chloride 0.9%
(Nebulised)
|
Formulary
|
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|
| 03.08 |
Aromatic inhalations |
|
|
| 03.09 |
Cough preparations |
|
|
Citric acid (oral presentations)
|
Formulary
|
|
|
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Methadone Hydrochloride
(oral solution and tablet)
|
Formulary
|
For use in palliative care only
|
|
|
Methadone Hydrochloride (Physeptone ®)
(solution for Injection)
|
Formulary
|
For Palliative care use only
|
|
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Methadone Hydrochloride oral solution (Methadose ®)
|
Formulary
|
For Palliative care use only
|
|
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Methadone Hydrochloride oral solution (Metharose ®)
|
Formulary
|
For Palliative care use only
|
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Methadone Hydrochloride oral solution (Physeptone ®)
|
Formulary
|
For Palliative care use only
|
|
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Methadone Linctus
|
Formulary
|
For Palliative care use only
|
|
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Morphine modified release capsule (Zomorph®)
|
Formulary
|
For Palliative care use only
|
|
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Morphine modified release tablet (MST Continus ®)
|
Formulary
|
For Palliative care use only
|
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Morphine oral solution
|
Formulary
|
For Palliative care use only
|
|
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Morphine oral solution
(Oramorph ®)
|
Formulary
|
For Palliative care use only
|
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Morphine solution for infusion
|
Formulary
|
For Palliative care use only
|
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Morphine solution for injection
|
Formulary
|
For Palliative care use only
|
|
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Morphine tablet (Sevredol®)
|
Formulary
|
For Palliative care use only
|
|
|
Pholcodine Linctus, BP
|
Formulary
|
OTC preparation suitable for self-care/purchase if appropriate
|
Conditions for which over the counter items should not routinely be prescribed in primary care: Guidance for CCGs
|
Pholcodine Linctus, Strong, BP
|
Formulary
|
OTC preparation suitable for self-care/purchase if appropriate
|
|
|
| 03.09.01 |
Cough suppressants |
|
|
| 03.09.01 |
Palliative care |
|
|
| 03.09.02 |
Expectorant and demulcent cough preparations |
|
|
Simple Linctus, BP
|
Formulary
|
OTC preparation suitable for self-care/purchase if appropriate
|
Conditions for which over the counter items should not routinely be prescribed in primary care: Guidance for CCGs
|
Simple Linctus, Paediatric BP
|
Formulary
|
OTC preparation suitable for self-care/purchase if appropriate
|
Conditions for which over the counter items should not routinely be prescribed in primary care: Guidance for CCGs
|
| 03.10 |
Systemic nasal decongestants |
|
|
Pseudoephedrine Hydrochloride
|
Formulary
|
OTC suitbale for self-care/purchase if appropraie
|
|
|
| 03.11 |
Antifibrotics |
|
|
Nintedanib (Ofev®)
|
Restricted
|
Hospital only- NHSE commissioned
In line with NICE and available from day 91 following publication of TA
|
NICE TA747: Nintedanib for treating progressive fibrosing interstitial lung diseases
NICE TA379: Nintedanib for treating idiopathic pulmonary fibrosis
|
Nintedanib (Vargatef®)
|
Formulary
|
Hospital ONLY
NHSE comissioned
In line with NICE and available from day 91 following publication of TA
|
NICE TA347: Nintedanib for previously treated locally advanced, metastatic, or locally recurrent non‑small‑cell lung cancer
|
Pirfenidone (Esbriet®)
|
Restricted
|
Hospital only - NHSE commissioned
|
NICE TA504: Pirfenidone for treating idiopathic pulmonary fibrosis
|
| 03.12 |
Other drugs for Interstitial lung disease (idiopathic pulmonary fibrosis) |
|
|
|
Azathioprine
|
Formulary
|
Sandwell
 Amber Shared Care Supported by an ESCA
ESCA Sandwell only
Dudley
Amber Shared Care Supported by an ESCA
ESCA Dudley only
Walsall
Not on formulary
Wolverhampton
Amber Shared Care Supported by an ESCA
ESCA for Wolverhampton only
|
ESCA: Azathioprine in conjuntion with prednisiolone - For the treatment of Interstitial lung disease
|
Methotrexate
(tablets)
|
Formulary
|
Sandwell
Amber SC Supported by ESCA
ESCA for Sandwelll
Walsall
Not on Formulary
Dudley
Not on Formulary
Wolverhampton
Amber SC Supported by ESCA
ESCA for Wolverhampton only
|
ESCA: Methotrexate - For the treatment of Interstitial lung diseas
|
Prednisolone
(plain tablets)
|
Formulary
|
•Plain tablets (not enteric coated)
•In conjunction with azathioprine for ILD
|
|
|
| 03.13 |
Nebulised antimicrobials for cystic fibrosis |
|
|
|
Amoxicillin
(Oral)
|
Formulary
|
|
|
|
Amoxicillin
(IV)
|
Formulary
|
|
|
|
Amoxicillin
(Nebulised)
|
Formulary
|
Hospital only
|
|
|
Amphotericin (Fungizone®)
(Nebulised)
|
Formulary
|
Hospital only
|
|
|
Amphotericin (Fungizone®)
(IV)
|
Formulary
|
|
|
|
Ceftazidime
(Nebulised)
|
Formulary
|
Hospital only
|
|
|
Cefuroxime
(Nebulised)
|
Formulary
|
Hospital only
|
|
|
Colistimethate sodium
(Colistin sulfomethate sodium nebulised)
|
Formulary
|
Commissioned by NHS England for Cystic Fibrosis only
|
|
|
Gentamicin
(Nebulised)
|
Formulary
|
Hospital only
|
|
|
Gentamicin
(IV)
|
Formulary
|
|
|
|
Lumacaftor with ivacaftor (Orkambi®)
|
Formulary
|
|
|
|
Magnessium sulfate
(IV)
|
Formulary
|
Severe acute asthma,Continuing respiratory deterioration in anaphylaxis
|
|
|
Meropenem
(IV & Nebulised)
|
Formulary
|
|
|
|
Tobramycin
(Nebulised)
|
Formulary
|
|
|
|
| 03.14 |
Monoclonal Antibody |
|
|
Benralizumab (Fasenra®)
(Solution for Injection)
|
Formulary
|
|
NICE TA565: Benralizumab for treating severe eosinophilic asthma
|
Lumacaftor with Ivacaftor (Orkambi®)
|
Formulary
|
|
|
|
Mepolizumab (Nucala®)
|
Formulary
|
In line with NICE
|
NICE TA671: Mepolizumab for treating severe eosinophilic asthma
|
Omalizumab (Xolair®)
|
Formulary
|
For specialist use only in line with NICE guidance below
NHS England is the responsible commissioner for use in Asthma
|
NICE TA278: Omalizumab for treating severe persistent allergic asthma
NICE TA339: Omalizumab for previously treated chronic spontaneous urticaria
|
Reslizumab (Cinqaero®)
|
Formulary
|
For specialist use only in line with NICE
NHS England is the responsible commissioner for use in Asthma
|
NICE TA479: Reslizumab for treating severe eosinophilic asthma
|
| 03.15 |
Cystic fibrosis |
|
|
| .... |
| Non Formulary Items |
Acetylcysteine effervescent tablet
|
Non Formulary
|
Brands:
|
|
|
Acrivastine
(Oral presentations)
|
Non Formulary
|
|
|
|
Alimemazine
(Oral presentations)
|
Non Formulary
|
|
|
|
Alimemazine (Alfresed®)
|
Non Formulary
|
|
|
|
Alimemazine (Vallergan®)
|
Non Formulary
|
|
|
|
Ammonia and Ipecacuanha Mixture BP
|
Non Formulary
|
|
|
|
Bambuterol (Bambec®)
|
Non Formulary
|
|
|
|
Beclometasone (Clipper®)
|
Non Formulary
|
Modified release tablets |
|
|
Beclometasone and formoterol (Luforbec®)
|
Non Formulary
|
|
|
|
Beclometasone Dipropionate (Easyhaler® )
|
Non Formulary
|
|
How to use an Easyhaler Inhaler
|
Beclometasone Dipropionate (Kelhale® )
|
Non Formulary
|
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
|
|
|
Beclometasone Dipropionate (Qvar®)
|
Non Formulary
|
- Qvar
- Qvar Autohaler
- Qvar Easi-Breathe
|
|
|
Beclometasone Dipropionate (Soprobec ®)
|
Non Formulary
|
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
|
|
|
Benzoin Tincture, Compound
|
Non Formulary
|
|
|
|
Benzoin tincture, compound (Friars Balsamsup>®)
|
Non Formulary
|
|
|
|
Beractant (Survanta®)
|
Non Formulary
|
|
|
|
Bilastine (Ilaxten®)
|
Non Formulary
|
|
|
|
Budesonide
(Spray)
|
Non Formulary
|
|
|
|
Budesonide (Budelin Novolizer®)
|
Non Formulary
|
How to use a Turbohaler Inhaler
|
|
|
Budesonide and formoterol (DuoResp Spiromax®)
|
Non Formulary
|
- DuoResp Spiromax 160/4.5 is therapeutically equivalent to Symbicort Turbohaler 200/6
- DuoResp Spiromax 320/9 is therapeutically equivalent to Symbicort Turbohaler 400/12
- Prescribe by brand to ensure patient receives the device they are used to
How to use a Spiromax Inhaler
|
|
|
Budesonide and Formoterol (Symbicort pMDI®)
|
Non Formulary
|
|
|
|
Budesonide and Formoterol (WockAIR®)
|
Non Formulary
|
|
|
|
Carbocisteine (Mucodyne®)
|
Non Formulary
|
|
|
|
Cetirizine Hydrochloride Capsules (Benadryl Allergy®)
|
Non Formulary
|
|
|
|
Chlorphenamine maleate (Allerief ®)
(Oral presentations)
|
Non Formulary
|
|
|
|
Chlorphenamine maleate (Hayleve®)
(Oral presentations)
|
Non Formulary
|
Prescribe generic |
|
|
Chlorphenamine maleate (Piriton®)
(Oral presentations)
|
Non Formulary
|
Prescribe generic |
|
|
Ciclesonide (Alvesco®)
(Inhaler)
|
Non Formulary
|
How to use a Metered Dose Inhaler
|
|
|
Clemastine (Tevegil®)
|
Non Formulary
|
|
|
|
Codeine linctus BP
|
Non Formulary
|
|
|
|
Codeine Linctus, Paediatric BP
|
Non Formulary
|
|
|
|
Codeine phosphate (Galcodine®)
|
Non Formulary
|
|
|
|
Codeine phosphate (oral presentations)
|
Non Formulary
|
|
|
|
Codeine phosphate solution for injection
|
Non Formulary
|
|
|
|
Cyproheptadine
|
Non Formulary
|
|
|
|
Cyproheptadine (Periactin®)
|
Non Formulary
|
|
|
|
Desloratadine
(Oral presentations)
|
Non Formulary
|
|
|
|
Desloratadine (Neoclarityn®)
(Oral presentations)
|
Non Formulary
|
|
|
|
Dextromethorphan / quinidine (Nuedexta®)
|
Non Formulary
|
|
|
|
Diphenhydramine (Nytol®)
|
Non Formulary
|
|
|
|
Drug Delivery Device
|
Non Formulary
|
- A2a Spacer
- A2a Spacer With Medium Mask
- A2a Spacer With Small Mask
- Able Spacer
- Able Spacer With Medium Mask
- Able Spacer With Small Mask
- Aer8
- Antistatic Space Chamber Plus
- Antistatic Space Chamber Plus Compact
- Antistatic Space Chamber Plus Compact With Large Mask
- Antistatic Space Chamber Plus Compact With Medium Mask
- Antistatic Space Chamber Plus Compact With Small Mask
- Antistatic Space Chamber Plus With Large Mask
- Antistatic Space Chamber Plus With Medium Mask
- Antistatic Space Chamber Plus With Small Mask
- Babyhaler
- Babyhaler Mini Mask
- Babyhaler Standard Mask
- Clip-tone E
- Clip-tone F
- Easychamber Spacer
- Easychamber Spacer With Adult Mask
- Easychamber Spacer With Child Mask
- Easychamber Spacer With Infant Mask
- E-chamber La Grande Spacer
- E-chamber La Petite Spacer
- E-chamber La Petite Spacer With Mask
- E-z Spacer
- Flo-tone Mdi Circular Fit
- Flo-tone Mdi Regular Fit
- Free Breath Spacer
- Free Breath Spacer With Adult Mask
- Free Breath Spacer With Child Mask
- Free Breath Spacer With Infant Mask
- Optichamber
- Optichamber Diamond
- Optichamber Diamond With Large Litetouch Mask 5 Years-adult
- Optichamber Diamond With Medium Litetouch Mask 1-5 Years
- Optichamber Diamond With Small Litetouch Mask 0-18 Months
- Pocket Chamber
- Pocket Chamber With Adult Mask
- Pocket Chamber With Child Mask
- Pocket Chamber With Infant Mask
- Pocket Chamber With Teenager Mask
- Rossmax Anti-static Aero Spacer
- Rossmax Anti-static Aero Spacer With Large Mask 5 Years-adult
- Rossmax Anti-static Aero Spacer With Medium Mask 1-5 Years
- Rossmax Anti-static Aero Spacer With Small Mask 0-18 Months
- Space Chamber Plus
- Space Chamber Plus Compact
- Space Chamber Plus Compact With Large Mask
- Space Chamber Plus Compact With Medium Mask
- Space Chamber Plus Compact With Small Mask
- Space Chamber Plus With Large Mask
- Space Chamber Plus With Medium Mask
- Space Chamber Plus With Small Mask
|
|
|
Ephedrine Hydrochloride
|
Non Formulary
|
|
|
|
Erdosteine (Erdotin®)
|
Non Formulary
|
|
|
|
Eucalyptus with menthol
|
Non Formulary
|
|
|
|
Eucalyptus with menthol Inhalation vapour
|
Non Formulary
|
|
|
|
Fluticasone and formoterol (Flutiform®)
|
Non Formulary
|
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device |
|
|
Fluticasone and salmeterol
(Inhalation powder)
|
Non Formulary
|
BRANDS
- Airflusal Forspiro
- Fixkoh Airmaster
- Fusacomb Easyhaler
- Seretide Accuhaler
- Stalpex
|
|
|
Fluticasone and salmeterol
(Pressurised inhalation)
|
Non Formulary
|
BRANDS
- Airflusal
- Aloflute
- Avenor
- Combisal
- Sirdupla- No dose counter although cost effective
- Sereflo -Even though cost effective and has dose counter, licensed for >18 yrs and clinicians would rather have patients on formoterol rather than salmeterol
|
|
|
Fluticasone and salmeterol (Seretide 500 Accuhaler®)
|
Non Formulary
|
|
|
|
Fluticasone and salmeterol (Seretide®)
(Inhaler)
|
Non Formulary
|
Seretide 250 Evohaler- Black from 23rd May 2023.
Ok for historic patients
- Should be prescribed by the intended brand to ensure patients are maintained on the formulation they are used to.
|
|
|
Formoterol Fumarate
|
Non Formulary
|
|
|
|
Glycopyrrolate/ indacaterol inhaler
|
Non Formulary
|
|
|
|
Glycopyrronium (Seebri breezhaler®)
|
Non Formulary
|
As per COPD guidelines from 11/10/22
How to use a Breezhaler Inhaler |
|
|
Glycopyrronium/indacaterol (Ultibro Breezhaler®)
|
Non Formulary
|
Black from 11/10/22
How to use a Breezhaler Inhaler |
|
|
Human alpha1- proteinase inhibitor (Respreeza®)
|
Non Formulary
|
|
|
|
Hypertonic sodium chloride
|
Non Formulary
|
AMPOULES
VIALS
- Bronchlear 6%
- Mucoclear 6%
- Pulmoclear 6%
- Resp-ease 6%
|
|
|
Indacaterol (Onbrez Breezhaler®)
|
Non Formulary
|
|
|
|
Indacaterol/Mometasone furoate (Atectura Breezhaler®)
|
Non Formulary
|
|
|
|
Ipratropium bromide
(Pressurised inhalation)
|
Non Formulary
|
- Atrovent
- Inhalvent(Black from 23/5/23. Okay for historic patients.Other LAMAs preferred)
|
|
|
Ipratropium bromide with salbutamol (Combivent®)
|
Non Formulary
|
|
|
|
Karvol
|
Non Formulary
|
|
|
|
Ketotifen (Ketofall®)
(Eye drops)
|
Non Formulary
|
|
|
|
Ketotifen (Zaditen®)
(Eye drops)
|
Non Formulary
|
|
|
|
Ketotifen (Zaditen®)
(Oral presentations)
|
Non Formulary
|
|
|
|
Levocetirizine
(Oral presentations)
|
Non Formulary
|
|
|
|
Levocetirizine (Xyzal®)
|
Non Formulary
|
|
|
|
Low range peak flow meter
|
Non Formulary
|
BRANDS
- Medi Peak Flow Meter
- Mini-wright Peak Flow
- Nspire Pocket Peak Peak
|
|
|
Mecysteine Hydrochloride (Visclair®)
|
Non Formulary
|
|
|
|
Menthol and Eucalyptus Inhalation BP 1980
|
Non Formulary
|
|
|
|
Mizolastine
|
Non Formulary
|
|
|
|
Mizolastine (Mizollen®)
|
Non Formulary
|
|
|
|
Mometasone (Asmanex®)
|
Non Formulary
|
|
|
|
Mometasone Furoate (Nasonex Spray®)
|
Non Formulary
|
Prescribe generically |
|
|
Mometasone/Glycopyrronium bromide/Indacaterol (Enerzair Breezhaler®)
|
Non Formulary
|
|
|
|
Montelukast (Singulair® )
(Oral presentations)
|
Non Formulary
|
Use in line with recommendations in BTS-SIGN asthma guideline |
|
|
Morphine modified release capsule (MXL®)
|
Non Formulary
|
|
|
|
Morphine modified release tablet (Morphgesic ®)
|
Non Formulary
|
|
|
|
Nedocromil (Tilade® CFC-free inhaler)
|
Non Formulary
|
|
|
|
Olodaterol (Striverdi Respimat ®)
|
Non Formulary
|
|
|
|
Orciprenaline Sulphate (Alupent®)
|
Non Formulary
|
|
|
|
Pholcodine oral solution (Covonia®)
|
Non Formulary
|
|
|
|
Pholcodine oral solution (Galenphol ®)
|
Non Formulary
|
|
|
|
Promethazine (Phenergan®)
(Oral presentations)
|
Non Formulary
|
|
|
|
Promethazine Hydrochloride (Phenergan®)
(solution for Injection)
|
Non Formulary
|
|
|
|
Promethazine Hydrochloride (Sominex®)
|
Non Formulary
|
|
|
|
Rupatadine
|
Non Formulary
|
|
|
|
Salbutamol
|
Non Formulary
|
- Salbulin Novolizer
- Ventolin Oral Solution
- Airomir
- Airomir Autohaler
- Ventolin Evohaler
- Salbutamol Tablet
|
|
|
Salmeterol
|
Non Formulary
|
- Serevent Accuhaler
- Serevent Evohaler
- Neovent
- Soltel
How to use an Accuhaler Inhaler
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device |
|
|
Salmeterol (Serevent® accuhaler)
|
Non Formulary
|
Removed from formulary for new patients with COPD February 2017
FOR EXISTING PATIENTS ONLY |
|
|
Sodium Cromoglicate
(Oral presentations)
|
Non Formulary
|
|
|
|
Sodium Cromoglicate (Comogen Easi-Breathe®)
|
Non Formulary
|
|
|
|
Sodium Cromoglicate (Intal®)
|
Non Formulary
|
|
|
|
Standard range peak flow meter
|
Non Formulary
|
BRANDS
- Airzone Peak Flow Meter
- Fyne Dynamics Pinnacle Peak Flow Meter
- Medi Peak Flow Meter
- Micropeak Peak Flow Meter
- Mini-wright Peak Flow Meter
- Nspire Piko-1 Peak Flow Meter
- Nspire Pocket Peak Peak Flow Meter
- Philips Respironics Personalbest Peak Flow Meter
- Vitalograph Child Peak Flow Meter
- Vitalograph Mypef Peak Flow Meter
- Vitalograph Peak Flow Meter
|
|
|
Terbutaline
|
Non Formulary
|
- Bricanyl Respules
- Bricanyl Tablet
|
|
|
Tezacaftor with ivacaftor
|
Non Formulary
|
|
|
|
Tezacaftor with ivacaftor (Symkevi ®)
|
Non Formulary
|
|
|
|
Tezacaftor with ivacaftor and elexacaftor
|
Non Formulary
|
|
|
|
Tezacaftor with ivacaftor and elexacaftor (Kaftrio®)
|
Non Formulary
|
|
|
|
Tiotropium
|
Non Formulary
|
- Acopair
- Braltus
- Spiriva
- Tiogiva
- Spiriva Handihaler
|
|
|
Zafirlukast
(tablets)
|
Non Formulary
|
- Accolate® brand discontinued March 2018
- No other generics available within UK
|
|
|
| |
Key |
|
Restricted Drug |
|
Unlicensed |
|
|
Link to adult BNF
|
|
|
Link to children's BNF
|
|
|
Link to SPCs
|
|
Cytotoxic Drug |
|
Controlled Drug |
|
|
High Cost Medicine |
|
Cancer Drugs Fund |
|
NHS England |
|
Homecare |
|
ICB |
|
Low carbon footprint |
|
Medium carbon footprint |
|
High carbon footprint |
|
| Status |
Description |
|
Medicines which are suitable for initiation and maintenance prescribing by primary and secondary care clinicians. These medicines should be initiated and prescribed within their licensed indications |
|
Amber Specialist Initiation: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate. This may be supported by a RICaD, annotated within the formulary entry. |
|
Amber Shared Care: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing, in accordance with an ESCA, annotated within the formulary entry. |
|
Amber Specialist Recommendation: Initiation and maintenance of prescribing in Primary Care following recommendation from a specialist. |
|
Medicines for initiation and maintenance prescribing by Specialists (hospital or GPs with Special Interest) only |
|
Positive NICE TA and /or awaiting local clarification on place in therapy; Please contact your Medicines Optimisation team for more information. |
|
Non-formulary Medicines which APC/Trust DTC has actively reviewed and do not recommend for use. |
|
Check Notes as varies across the area |
|
|
|
