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 Formulary Chapter 2: Cardiovascular system - Full Chapter
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02.05  Expand sub section  Drugs affecting the renin-angiotensin system and some other antihypertensive drugs
Ambrisentan
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Formulary
Red
 
 
Macitentan (Opsumit®)
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Formulary
Red
NHS England

NHS England commissioned

 
 
Metirosine
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Formulary
Red
 
 
Milrinone (Primacor®)
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Formulary
Red
 
 
02.05.01  Expand sub section  Vasodilator antihypertensive drugs
Hydralazine
(tablets)
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Formulary
Green
 
 
Minoxidil (Loniten®)
(Tablets)
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Formulary
Amber Recommended

Use on specialist advice only

 
 
Bosentan
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Formulary
Red
 
 
Iloprost
(Injection)
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Formulary
Red
 
 
Iloprost nebules (Vantavis®)
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Formulary
Red
NHS England

NHS England commissioned 

 
 
Sildenafil
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Formulary
Red
 
 
Sodium nitroprusside
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Formulary
Red

Injection (Secondary Care only)

 
 
02.05.02  Expand sub section  Centrally acting antihypertensive drugs
Clonidine Hydrochloride (Catapres®)
(tablets)
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Formulary
Red


Use only on advice of specialist

 
 
Clonidine Liqiud
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Formulary
Amber Initiation
 
 
Methyldopa
(Tablets)
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Formulary
Amber Recommended
 
 
Moxonidine
(Tablets)
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Formulary
Green
 
 
02.05.03  Expand sub section  Adrenergic neurone blocking drugs
02.05.04  Expand sub section  Alpha-adrenoceptor blocking drugs to top
Doxazosin
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Formulary
Green
 
Link  Patient Information: Changes to doxazosin prescribing
 
02.05.04  Expand sub section  Phaeochromocytoma
Phenoxybenzamine
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Formulary
Amber Recommended
 
 
02.05.05  Expand sub section  Drugs affecting the renin-angiotensin system
02.05.05  Expand sub section  Heart Failure
Sacubitril valsartan (Entresto®)
(film coated tablets)
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Formulary

Use current status at Place/Trust

Sandwell

Amber Initiation Supported by RICaD

Sacubatril valsartan(Entresto) RICaD -Sandwell only

Wolverhampton

Amber Initiation

Walsall

Amber Initiation

Dudley

Amber Initiation

Entresto-Implementation of Entresto (Sacubitril/Valsartan) in Dudley Health Economy

 
Link  NICE TA388:Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fraction
 
02.05.05.01  Expand sub section  Angiotensin-converting enzyme inhibitors (ACE inhibitors)
Perindopril erbumine
(Tablets)
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Formulary
Green

DO NOT PRESCRIBE as perindopril arginine salt-Perindopril arginine is Black on the formulary

 
 
Ramipril
(Capsules, Tablets)
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Formulary
Green

Prescribe as capsules

 
 
Lisinopril
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Formulary
Green
 
 
Captopril
(tablets)
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Formulary
Amber Recommended

For existing patients and Paediatric use

 
 
02.05.05.02  Expand sub section  Angiotensin-II receptor antagonists to top
Candesartan cilexetil
(Tablets)
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Formulary
Green
 
 
Irbesartan
(Tablets)
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Formulary
Green
 
 
Losartan
(Tablets)
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Formulary
Green
 
 
Valsartan
(Capsules)
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Formulary
Green
 
 
02.05.05.03  Expand sub section  Renin inhibitors
Aliskiren (Rasilez®)
(Tablets)
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Formulary
Red

Guidance for CCGs: Items which should not be routinely prescribed in primary care

 
 
 ....
 Non Formulary Items
Atenolol with nifedipine

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Non Formulary
Black
Azilsartan

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Non Formulary
Black
Captopril and Hydrochlorothiazide  (Capozide®)

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Non Formulary
Captopril and Hydrochlorothiazide  (Co-zidocapt®)

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Non Formulary
Cilazapril  (Vascace®)

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Non Formulary
Co-flumactone

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Non Formulary
Black
Co-tenidone (atenolol and chlortalidone)

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Non Formulary
Black
Cozaar- Comp®

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Non Formulary
Enalapril
(tablets)

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Non Formulary
Black

For existing patients only

Enalapril Meleate and Hydrochlorothiazide  (Innozide®)

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Non Formulary
Ephedrine

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Non Formulary
Black
Eprosartan  (Teveten®)

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Non Formulary
Black
Fosinopril Sodium

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Non Formulary
Black
Guanethidine Monosulphate

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Non Formulary
Black
Hydralazine Hydrochloride  (Apresoline®)

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Non Formulary
Hydrochlorothiazide

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Non Formulary
Black
Imidapril Hydrochloride  (Tanatril®)

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Non Formulary
Black
Indoramin  (Baratol®)

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Non Formulary
Black
Indoramin  (Doralese®)

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Non Formulary
Black
Irbesartan with hydrochlorothiazide

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Non Formulary
Black
Lisinopril  (Zestril®)

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Non Formulary
Black
Lisinopril and Hydrochlorothiazide  (Carace® Plus, Lisicostad®, Zestoretic®)

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Non Formulary
Black
Losartan with hydrochlorothiazide

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Non Formulary
Black
Moexipril Hydrochloride  (Perdix®)

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Non Formulary
Olmesartan  (Sevikar®)

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Non Formulary
Black
Olmesartan with amlodipine

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Non Formulary
Black
Olmesartan with amlodipine and hydrochlorothiazide

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Non Formulary
Black
Olmesartan with hydrochlorothiazide

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Non Formulary
Black
Perindopril

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Non Formulary
Black
Perindopril Arginine  (Coversyl® Arginine)
(Tablets)

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Non Formulary
Black

In line with NHS England's Guidance for CCGs: Items which should not routinely be prescribed in primary care (Dec 2017)

Click here to access guidance

Link  Patient Information: Changes to perindopril arginine prescribing
Perindopril arginine with indapamide

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Non Formulary
Black
Phentolamine

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Non Formulary
Black
Prazosin

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Non Formulary
Black
Prazosin  (Hypovase®)

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Non Formulary
Quinapril

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Non Formulary
Black
Quinapril and Hydrochlorothiazide

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Non Formulary
Black
Ramipril and Felodipine  (Triapin®)

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Non Formulary
Black
Rasitro®

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Non Formulary
Sevikar HCT®

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Non Formulary
Black
Sitaxentan Sodium  (Thelin®)

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Non Formulary
Tadalafil

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Non Formulary
Black

Non formulary for:

- Lower urinary tract symptoms in benign prostatic hyperplasi

Tadalafil  (Adcirca®)

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Non Formulary
Telmisartan

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Non Formulary
Black
Telmisartan with hydrochlorothiazide

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Non Formulary
Black
Terazosin

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Non Formulary
Black
Terazosin  (Hytin®)

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Non Formulary
Timolol with amiloride and hydrochlorothiazide

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Non Formulary
Black
Timolol with bendroflumethiazide

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Non Formulary
Black
Tolazoline

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Non Formulary
Trandolapril  (Gopten®)

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Non Formulary
Black
Trandolapril and Verapamil  (Tarka®)

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Non Formulary
Treprostinil

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Non Formulary
Black
Triamterene with chlortalidone

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Non Formulary
Black
Valsartan with hydrochlorothiazide

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Non Formulary
Black
  
Key
Restricted Drug Restricted Drug
Unlicensed Drug Unlicensed
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
ICB
ICB
Green Low Carbon

Low carbon footprint

Amber Medium Carbon

Medium carbon footprint

Red High carbon footprint

High carbon footprint

Status Description

Green

Medicines which are suitable for initiation and maintenance prescribing by primary and secondary care clinicians. These medicines should be initiated and prescribed within their licensed indications  

Amber Initiation

Amber Specialist Initiation: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate. This may be supported by a RICaD, annotated within the formulary entry.  

Amber SC

Amber Shared Care: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing, in accordance with an ESCA, annotated within the formulary entry.  

Amber Recommended

Amber Specialist Recommendation: Initiation and maintenance of prescribing in Primary Care following recommendation from a specialist.  

Red

Medicines for initiation and maintenance prescribing by Specialists (hospital or GPs with Special Interest) only  

Grey

Positive NICE TA and /or awaiting local clarification on place in therapy; Please contact your Medicines Optimisation team for more information.  

Black

Non-formulary Medicines which APC/Trust DTC has actively reviewed and do not recommend for use.  

Multiple

Check Notes as varies across the area  

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