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NHS NEL
Demonstration Formulary
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 Formulary Chapter 1: Gastro-intestinal system - Full Chapter
01.02  Expand sub section  Antispasmodics and other drugs altering gut motility
 link Link    NICE CG49: Faecal incontinence in adults: management
 link Link    NICE CG61: Irritable bowel syndrome in adults: diagnosis and management
 link Link    NICE CG99: Constipation in children and young people: diagnosis and management
01.02  Expand sub section  Antimuscarinics
01.02  Expand sub section  Other antispasmodics
01.02  Expand sub section  Motility stimulants
Domperidone
(Tablets, Suspension, Suppositories)
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Green

The MHRA has issued new advice for domperidone which states that it is no longer licensed for the relief of nausea and vomiting in children under the age of 12 years or those weighing less than 35kg (16th December 2019).

See MHRA Dug Safety Update

Domperidone is no longer recommended for managing heartburn,bloating and stomach discomfort

It should only be used for relief of nausea and vomiting at low doses for short periods (generally upto 1 week)

MHRA advice on domperidone

 
Link  MHRA: Domperidone: risk of cardiac side effects (Published 11 December 2014)
Link  NICE: Promoting tolerance of enteral feeds in children and young people: domperidone
 
 ....
Key
Restricted Drug Restricted Drug
Unlicensed Drug Unlicensed
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 Link to adult BNF
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 Link to children's BNF
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 Link to SPCs
Cytotoxic Drug
 Cytotoxic Drug
CD
 Controlled Drug
High Cost Medicine
 High Cost Medicine
Cancer Drugs Fund
 Cancer Drugs Fund
NHSE
 NHS England
Homecare
 Homecare
ICB
 ICB
Green Low Carbon

Low carbon footprint
Amber Medium Carbon

Medium carbon footprint
Red High carbon footprint

High carbon footprint
Status Description

Green

 Medicines which are suitable for initiation and maintenance prescribing by primary and secondary care clinicians. These medicines should be initiated and prescribed within their licensed indications  

Amber Initiation

 Amber Specialist Initiation: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing when appropriate. This may be supported by a RICaD, annotated within the formulary entry.  

Amber SC

 Amber Shared Care: Initiation and maintenance of prescribing by Specialists and transfer to Primary Care prescribing, in accordance with an ESCA, annotated within the formulary entry.  

Amber Recommended

 Amber Specialist Recommendation: Initiation and maintenance of prescribing in Primary Care following recommendation from a specialist.  

Red

 Medicines for initiation and maintenance prescribing by Specialists (hospital or GPs with Special Interest) only  

Grey

 Positive NICE TA and /or awaiting local clarification on place in therapy; Please contact your Medicines Optimisation team for more information.  

Black

 Non-formulary Medicines which APC/Trust DTC has actively reviewed and do not recommend for use.  

Multiple

 Check Notes as varies across the area  

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