netFormulary
 Report : A-Z of formulary items 23/12/2024 03:39:00
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Section Name Details
A5.02.08  

Consider first line dressings appropriate to wound bed type and exudate level

A5.04.01  

Before using active products, ensure all potential reasons for non-healing have been explored.

A5.05.02  

Consider standard interactive dressings first.

A5.06.01  

Consider standard interactive dressings first as advised by Tissue Viability Nurse.

A5.10   Consider standard dressings first
06.04.01.01 Evorel Sequi® 
05.03 Molnupiravir 
05.01.09 Rifampicin  Rimactane®

Hospital use only under microbiological and Tuberculosis specialist advice 

01.06.04 Sodium Citrate 

Micro-enema

Microlette®, Relaxit® and Micralax®

20 3% acetic acid for Barrett’s oesophagus surveillance 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

10.02.01 3,4-diaminopyridine (3,4-DAP) 

Hospital use only

A5.15 3M Cavilon Durable Barrier Cream 

Preferred local option

Skin protectant
Type of wound product is suitable for
Intact skin
As a barrier against bodily fluids, prevention of skin damage associated with incontinence
Can be used alongside containment products
Can be used to prevent friction to vulnerable areas of skin
Frequency of use
Reapply sparingly twice daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use on infected skin
Not be used as an emollient
Not to be used around the peri wound
Can increase adherence of some dressing products and therefore care should be taken when adhesive products are being used in conjunction with the cream on people with fragile skin
Rationale for inclusion in formulary
The only barrier cream that can be used in conjunction with containment products without blocking the absorption of the pad
Cost effective, does not require reapplication at every episode of hygiene

A5.15 3M Cavilon No Sting Barrier Film Pump Spray and Applicators 

Preferred local option

Protective transparent barrier film

Type of wound product is suitable for
Superficial broken skin and abrasions
As a barrier against bodily fluids, prevention of skin damage associated with incontinence
Can be used:
-alongside containment products,
-to prevent friction to vulnerable areas of skin
-on superficial abrasions caused by incontinence
-to protect peri wound from exudate
-to protect against aggressive adhesive products
-to protect the skin surrounding stoma sites

Frequency of use
Every 72 hours

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use on infected skin
Allow product to dry before applying the containment products, dressings or clothing (30 seconds)
Too many layers can make the area of skin feel stiff
Can affect electrode readings in the treated area

Rationale for inclusion in formulary
Available in a foam applicator and spray to aid application
Non sticky after use
Can be used on broken areas of skin
Cost effective, does not require reapplication at every episode of hygiene

05.03.01 Abacavir 
05.03.01 Abacavir and Lamivudine 
05.03.01 Abacavir with dolutegravir and lamivudine Triumeq ®
10.01.03 Abatacept Orencia®

Hospital ONLY

£££££

Available via home Care

NHSE commissioned for Juvenile Arthritis and paediatric indications where adult TA available

08.01.05 Abemaciclib Verzenios®

In line with NICE

Providers are NHS hospital trusts

08.03.04.02 Abiraterone Zytiga®

Commissioned by NHSE or via Cancer Drug Fund

08.01.05 Acalabrutinib Calquence®

In line with NICE

04.10.01 Acamprosate Campral EC®

For initiation by specialists in substance misuse

02.08 Acenocoumarol Sinthrome®

Use on the advice of a specialist only

02.02.07 Acetazolamide 
11.06 Acetazolamide 

Hospital only

11.06 Acetazolamide 

Used alone for short term post op only. Can be used with beta-blocker or other ocular hypotensive
Systemic absorption can give rise to sulphonamide associated side effects

On Specialist Ophthalmologist Recommendation

11.06 Acetazolamide SR 

Used alone for short term post op only. Can be used with beta-blocker or other ocular hypotensive
Systemic absorption can give rise to sulphonamide associated side effects

On Specialist Ophthalmologist Recommendation

12.01.01 Acetic Acid 2% Earcalm ®
20 Acetic Acid Solution 3% 

Restricted for use by endoscopy only 

03.07 Acetylcysteine 

Brand: Parvolex

03.07 Acetylcysteine oral presentations
  • Brands (NACSYS and Nexus)
  • See brands -Prescribe as Acetylcyteine S/f tabs
11.08.01 Acetylcysteine 10% Ilube®
11.08.01 Acetylcysteine 5% with Hypromellose 0.35% Ilube®
03.07 Acetylcysteine effervescent tablet Aceteff®

Acetylcysteine SF effervescent tabs most cost effective

05.03.02.01 Aciclovir 

 

Tablets most cost effective choice 

Dispersible tablets £

Suspension ££

05.03.02.01 Aciclovir 
11.03.03 Aciclovir  
13.10.03 Aciclovir 5% cream 
05.03.02 Aciclovir lauriad Sitavig
01.01.02 Acidex 
13.05.02 Acitretin Neotigason®

Prescribed only by or under the supervision of a Consultant Dermatologist. not licensed for GP's to prescribe

03.01.02 Aclidinium Eklira Genuair®

For COPD only

How to use a Genuair Inhaler

03.01.04 Aclidinium & formoterol inhaler Duaklir Genuair®

 

How to use a Genuair Inhaler

A5.08.07 Actico® 

Preferred local option

Cohesive inelastic high compression bandage. Short stretch bandage

Type of wound product is suitable for
Venous leg ulceration
Lymphoedema
Management of chronic oedema

Duration dressing remains on wound before changing
Daily to 7 days

Frequency of dressing change
Dependant on exudate levels if wound present or oedema management.

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.
Not recommended on those patients with an ABPI lower than 0.8. Caution in diabetic patients
Caution when cardiac overload or renal failure present or suspected.

Rationale for inclusion in formulary
Only cohesive short stretch bandage. Nurses competent in its usage.

19.08 ActiFormCool®  Type of wound product is suitable for
Necrotic or sloughy wounds that require hydration and cooling pain relief
Can be used on dry wounds with the backing left in place
Cut to shape of the wound
Requires a secondary dressing

Duration dressing remains on wound before changing
1-3 days if dressings become discoloured or opaque or at first signs of exudate strike through

Frequency of dressing change
If dressing becomes discoloured or opaque or at first signs of exudate strike through. Do not allow to dry out

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Should not be used as a covering for deep narrow cavities or sinuses. Do not use on infected wounds.
Not suitable for heavily exuding wounds, known product or component sensitivity. Not for application on ischaemic wounds.

Rationale for inclusion in formulary
Dry necrotic, sloughy or painful wounds
For ease of application - sheet gel rather than liquid
Can be used prior to larval therapy to maintain moisture levels
Primary dressing-see below for secondary:
EXUDATE SECONDARY DRESSING WITH HYDROGEL
None/dry wound Semi-permeable film to reduce moisture loss
Light Non-adherent dressing + tape or Mepore
Moderate Surgical absorbent + tape
A5.02.01 ActiFormCool® 

Preferred local option

Type of wound product is suitable for
Necrotic or sloughy wounds that require hydration and cooling pain relief
Can be used on dry wounds with the backing left in place
Cut to shape of the wound
Requires a secondary dressing
Duration dressing remains on wound before changing
1-3 days if dressings become discoloured or opaque or at first signs of exudate strike through
Frequency of dressing change
If dressing becomes discoloured or opaque or at first signs of exudate strike through. Do not allow to dry out
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Should not be used as a covering for deep narrow cavities or sinuses. Do not use on infected wounds.
Not suitable for heavily exuding wounds, known product or component sensitivity. Not for application on ischaemic wounds.
Rationale for inclusion in formulary
Dry necrotic, sloughy or painful wounds
For ease of application - sheet gel rather than liquid
Can be used prior to larval therapy to maintain moisture levels
Primary dressing

A5.03.01 Actilite 

Specialist recommendation only
Non-adherent viscose net dressing 99% Manuka honey and 1% Manuka oil.
Type of wound product is suitable for
A primary dressing for low to moderate shallow exuding wound with light slough. Granulating or
epithelialising wounds with clinical signs of infection. Requires a secondary dressing.
Max Duration dressing remains on wound before changing
3-7 Days
Frequency of dressing change
3 to 7 days depending on exudate
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known allergy to Bee Venom and Honey products
Blood sugars should be monitored in patients with diabetes
Stinging sensation may be experienced. If unacceptable for patient then discontinue.
Rationale for inclusion in formulary
For antimicrobial and de-sloughing properties
Ease of application
Can be cut to size
Easy removal in one piece
Availability of different sizes
Not found to be harmful to peri-wound skin
Malodour
Cost effective

A5.02.05 ActivHeal® 

PODIATRY ONLY

Two layer dressing consisting of a polyurethane bacterial barrier membrane with a centrally located hydrophilic pad +/- acrylic adhesive border.

Type of wound product is suitable for
Moderately exuding wounds with signs of granulation, epithelialisation or slough. Can be used as primary or secondary

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
Up to 7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Full thickness burns
Surgical implantations

Rationale for inclusion in formulary
Cost effective
Simple to use on the foot and digits
Can be cut to shape

A5.02.05 ActivHeal® Foam Tracheostomy 

Specialist recommendation only

Preferred local option


Tracheostomy foam dressing
Type of wound product is suitable for
ActivHeal® Foam Tracheostomy dressing has a fenestration, which allows the dressing to fit neatly around a tracheostomy tube. The dressing can also be used around intubation and cannula insertion procedures, external bone fixators and appropriately-sized wound drainage tubes.
Duration dressing remains on wound before changing
Dependant on clinical need and soiling
Frequency of dressing change
Up to 7 days, dependant on clinical need and soiling
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use if reaction to any of its components
Rationale for inclusion in formulary
Specific dressing shaped and able to cut for tracheostomies.
Cost effective

A5.03.01 Activon Tube 

Specialist recommendation only

Preferred local option

100% medical grade Manuka Honey.
Type of wound product is suitable for
Use as topical treatment for infected sloughy shallow or cavity wounds. Primary or addition to other Activon products. Requires secondary dressing.
Max Duration dressing remains on wound before changing
Up to 4 days
Frequency of dressing change
Daily in acute infection
Up to 4 days in chronic infection dependant on exudate
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Wounds with active blood loss
Known allergies to bee Venom and Honey products
Blood sugars should be monitored in diabetic patients
Stinging sensation may be experienced – discontinue if not tolerant.
Rationale for inclusion in formulary
Anti-microbial and de-sloughing properties
Control of odours
Benefit of adding to other action products and increasing honey
Suitable for use in cavities
Cost effective

A5.03.01 Activon Tulle 

Specialist recommendation only

Preferred local option

Knitted viscose mesh impregnated with 100% Manuka Honey.
Type of wound product is suitable for
Creates a moist healing environment effectively eliminates odour. Provides anti-microbial action.
Debrides and de-sloughs shallow wounds where the exudate level has started to decrease. Requires secondary dressing
Max Duration dressing remains on wound before changing
Up to 4 days
Frequency of dressing change
Daily in acute infection
Up to 4 days for chronic infection depending on exudate
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Wounds with active blood loss
Known allergies to bee Venom and Honey products
Blood sugars should be monitored in diabetic patients
Stinging sensation may be experienced – discontinue if not tolerant.
Rationale for inclusion in formulary
Anti-microbial and de-sloughing properties for wounds with reduced levels of exudate.
Control of odours
Ease of application and removal in one piece
Can be cut to size
Available to various size
Cost effective

01.05.03 Adalimumab Humira®

For specialist use only in line with NICE guidance

£££££

10.01.03 Adalimumab 

Specialist/hospital use only

£££££

Biosimilar brands of Humira® available:

  • Amgevita®
  • Hulio®
  • Hyrimoz®
  • Imraldi®

NHSE commissioned for paediatric indications where adult TA available

11.99.99.99 Adalimumab Humira®
  • In line with NICE
13.05.03 Adalimumab 

Initiated by hospital consultant only

In line with NICE 

13.06.01 Adapalene 

Avoid in pregnancy

Use topical retinoids at all stages of acne to help minimise formation of comedones.

May cause irritation, build upfrequency or duration of application over 2-3 weeks.

13.06.01 Adapalene with benzyl peroxide  Epiduo®

May be used in preference to antimicrobial -containing agents.

09.05.02.01 Addiphos® 
05.03.03 Adefovir Dipivoxil Hepsera®
02.03.02 Adenosine Adenocor®

Hospital use only

02.06 Adrenaline / Epinephrine 
03.04.03 Adrenaline / epinephrine EpiPen®
03.04.03 Adrenaline / Epinephrine Jext®
03.04.03 Adrenaline / Epinephrine Emerade®

There has been a patient-level recall of Emerade 500 micrograms pens. This follows earlier recalls for Emerade 150 and 300 microgram pens. (18 May 2020)

Supplies of Emerade will therefore no longer be available in the UK until technical issues with the pen are resolved.

MHRA - Advice for patients with an Emerade 500 microgram auto-injector letter

21 Adrenaline / Epinephrine 
  • The risk of bleeding can be affected by other factors such as the presence of fungating or infected wounds. Smaller bleeds can be palliated using topical adrenaline. 
03.04.03 Adrenaline / Epinephrine 1 in 1,000 Minijet ® Adrenaline 1 in 1000
03.04.03 Adrenaline / Epinephrine 1 in 10,000 Minijet ® Adrenaline 1 in 10000
03.01.05 AeroChamber Plus® 
08.01.05 Afatinib Giotrif®

Commissioned by NHSE

In line with NICE

11.08.02 Aflibercept Eylea®

Use in line with NICE

04.03.04 Agomelatine Valdoxan®

Supported by a RICaD (in development)

05.05 Albendazole 

Unlicensed

09.02.02.02 Albumin human solution 

Hospital use only

08.01.05 Alectinib Alecensa®

In line with NICE

08.02.03 Alemtuzumab Lemtrada®

Hospital only

In line with NICE

06.06 Alendronic Acid 



06.06.02 Alendronic acid Binosto®
09.06.04 Alfacalcidol 

Amber Initiation  Oral preparations
Red Traffic Light  Injection-hospital only

15.01.04.03 Alfentanil  Hospital only.
Palliative care team only for end of life care.
15.01.04.03 Alfentanil Rapifen®

Hospital only

21 Alfentanil  
15.01.04.03 Alfentanil intensive care 

Hospital only.
Palliative care team recommendation during end of life care only.

07.04.01 Alfuzosin Hydrochloride 

Reduce BP - care with other antihypertensives
Caution in elderly
Care with hepatic and severe renal impairment
Contraindicated in postural hypotension or micturition syncope.

Caution in patients with a history of QT prolongation or concomitant use with other drugs known to prolong QT interval.

01.03 Alginic acid 
A5.03.01 Algivon 

Specialist recommendation only

Preferred local option

Alginate dressing impregnated with 100% Manuka Honey.
Type of wound product is suitable for
Primary dressing for infected, shallow cavity wounds, particularly if necrotic or malodorous with
moderate exudate. Requires secondary dressing.
Max Duration dressing remains on wound before changing
Up to 4 days for chronic infection
Frequency of dressing change
Daily for acute infection
Up to 4 days for chronic infection/depending upon exudate
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Wounds with active blood loss
Known allergy to be venom and honey products
Blood sugars should be monitored in diabetic patients
Stinging sensation may be experienced – discontinue if not tolerated
Rationale for inclusion in formulary
Antimicrobial and de sloughing properties
Absorbent
Malodour
Ease of application and removal in one piece
Can be cut to size
Available in various sizes
Can be shaped to wound size and depth
Cost effective

09.08.01 Alglucosidase alfa Myozyme® NHSE commissioned
02.12 AlirocumabRestricted Item  Praluent® In line with NICE.
02.05.05.03 Aliskiren Rasilez®

Guidance for CCGs: Items which should not be routinely prescribed in primary care

13.05.01 Alitretinoin Toctino® Dermatologist use only in line with NICE.
19.22 ALL SILVER DRESSINGS  There is insufficient evidence to make recommendations on the routine use of silver dressings. Current literature states that the content and type of silver manufactured in such dressings varies widely making it difficult to ascertain the true benefits in terms of clinical effectiveness and cost. In addition recent comparative studies of silver with more conventional antimicrobials such as iodines and honey have shown poor performance indicators favouring more conventional antimicrobials (Thorn et al, 2009 and Du Toit & Page, 2009). With these findings in mind it is advocated that silver dressings be considered as a last dressing choice.
However, where a clinician considers a silver dressing is appropriate, the dressing with the lowest acquisition cost appropriate to the clinical indication should be selected.
This decision must be discussed with and agreed by the Prescriber.
The clinician must then complete the Formulary Exceptions Monitoring Form and Authorisation Form for Silver Dressings and return to Tissue Viability Service for approval.
If approved, the wound should be reassessed at 10-14 days and if:
• Wound progressing normally – stop silver
• Signs of reduced bacterial load – continue with silver to a maximum of another 2 weeks
• No improvements – consider another antimicrobial and seek medical or tissue viability advice as appropriate.
The use of silver dressings will be monitored and may be the subject of future clinical audit.
A5.03.03 ALLEVYN®Ag 

Hospital use only for pin sites
A non adherent foam dressing impregnated with silver sulphadiazine that can be cut to suit the patient
Type of wound product is suitable for
For use around infected pin sites
Duration dressing remains on wound before changing
Daily or as directed
Frequency of dressing change
Daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Patients who have a known sensitivity to Silver Sulphadiazine or Sulphonamides
Females who are at or near full term pregnancy or lactating
Not for use on neonates or new born infants during the first month of life
Rationale for inclusion in formulary
Used around infected pin sites in patients with external metalwork to help reduce bacterial load

A5.02.05 ALLEVYN®  

Available in adhesive, non adhesive and gentle
Type of wound product is suitable for
Wound management by secondary intention on acute, chronic, full thickness or partial thickness or shallow granulating wounds including pressure ulcers, leg ulcers, diabetic foot ulcers, malignant wounds surgical wounds, malignant wounds donor sites and fungating ulcers
Can be used as a primary or secondary dressing
Duration dressing remains on wound before changing
Can stay in place up to 3-7 days
Frequency of dressing change
Dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
In common with all adhesive products, some cases of irritation and/or maceration of the skin may occur.
It should be noted that inappropriate use or too frequent dressing changes, particularly in patients with fragile skin, can result in skin stripping. If this occurs change to the ALLEVYN® gentle border range.
If redness or sensitisation occur, discontinue use
Caution under compression when exudate levels are moderate to high.
Rationale for inclusion in formulary
Can be used for low to moderate exudate levels
Different sizes and shapes available
Cost effective

A5.02.05 ALLEVYN® cavity 

Specialist recommendation only

Type of wound product is suitable for
Wound management by secondary intention on acute, chronic, full thickness or partial thickness or shallow granulating wounds including pressure ulcers, leg ulcers, diabetic foot ulcers, malignant wounds surgical wounds, malignant wounds donor sites and fungating ulcers. Can be used as a primary or secondary dressing

Duration dressing remains on wound before changing
Can stay in place up to 3-7 days

Frequency of dressing change
Dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
In common with all adhesive products, some cases of irritation and/or maceration of the skin may occur.It should be noted that inappropriate use or too frequent dressing changes, particularly in patients with fragile skin, can result in skin stripping. If this occurs change to the ALLEVYN® gentle border range.If redness or sensitisation occur, discontinue use. Caution under compression when exudate levels are moderate to high.

Rationale for inclusion in formulary
Can be used for low to moderate exudate levels. Different sizes and shapes available. Cost effective

A5.02.03 Allevyn® Life 

Specialist recommendation only

Hydrocellular foam dressing

Type of wound product is suitable for
Shallow granulating wounds, acute and chronic exuding wounds, full and partial thickness wounds
such as leg ulcer, malignant wound, surgical wound. Primary dressing
Silicone adhesive

Duration dressing remains on wound before changing
Up to 7 days dependent on dressing indicators

Frequency of dressing change
Up to 3 times a week maximum

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use with oxidising agents such as hypochlorite solutions or hydrogen peroxide Discontinue if reddening or sensitivity occurs.
Do not cut
Caution under compression where exudate levels are moderate to high

Rationale for inclusion in formulary
Fragile skin with absorbency and conformability, problematic healing wounds. Odour control.

A5.02.05 Allevyn® Non-Adhesive  

Type of wound product is suitable for
Wound management by secondary intention on acute, chronic, full thickness or partial
thickness or shallow granulating wounds including pressure ulcers, leg ulcers, diabetic foot ulcers, malignant wounds surgical wounds, malignant wounds donor sites and fungating ulcers
Can be used as a primary or secondary dressing

Duration dressing remains on wound before changing
Can stay in place up to 3-7 days

Frequency of dressing change
Dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
In common with all adhesive products, some cases of irritation and/or maceration of the skin may occur.
It should be noted that inappropriate use or too frequent dressing changes, particularly in patients with fragile skin, can result in skin stripping. If this occurs change to the Allevyn® gentle border range.
If redness or sensitisation occur, discontinue use
Caution under compression when exudate levels are moderate to high.

Rationale for inclusion in formulary
Can be used for low to moderate exudate levels
Different sizes and shapes available
Cost effective

09.05.01.01 Alliance calcium syrup 

Replacement for Calcium Sandoz® (Discontinued)

10.01.04 Allopurinol 
06.01.02.03 Alogliptin Vipidia®

In line with NICE No significant clinical benefit when used in combination with Insulin – avoid using together 

06.01.02.03 Alogliptin with Metformin Vipdomet®

A variety of combinations tablets (dual therapies) of oral diabetes medication can be prescribed and are available in the Drug Tariff.   

Overall, they may improve compliance in patients, however some combinations would then not allow the flexibility in dosing that is required for diabetes management and in some cases increase the tablet burden. There are specific sick-day rules related to stopping certain medication which would be further complicated where they are not prescribed in their separate formulations.

Furthermore, for the overall health economy not all combination therapies are cost-effective and this will be increasingly so as the patents expire over the near future.

There are some combination therapies that are not recommended in the oral guidance and clinicians are guided to review and discuss these with patients as part of shared -care decision making. 

There are complexities also around the lack of licensing of dual therapies in specific cohorts of patients, related to prescribing for the indication of heart failure or renal disease, making this a complex area for prescribing in primary care. 

02.14 Alprostadil 
07.01.01.01 Alprostadil Prostin VR®
07.04.05 Alprostadil Vitaros®

Specialist initiation only

For patients who would otherwise use alprostadil injection

07.04.05 Alprostadil Intracavernosal injection Caverject®

Not prescribable under the NHS except to treat erectile dysfunction in men who:

Have diabetes, multiple sclerosis, Parkinson's Diseas, poliomyelitis, prostate cancer, severe pelvic injury, single gene neurological disease, spina bifda or psinal cord injury.

Are receiving renal dialysis for renal failure

Have had radical pelvic surgery, prostatectomy (including transurethral resection of the prostate), or kidney transplant

Were receiving Caverject®, Erecnos®, MUSE®, Viagra®, or Viridal® for erectile dysfunction at the expense of the NHS on 14th September 1998

Are suffering severe distress as a result og impotence (prescribed in specialist centres only)

02.10 Alteplase 

Hospital only drug

09.04 AltraJuce 
09.04 Altraplen Compact® (formally know as Nutriplen® 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Alternative to second line supplement choice
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–6 years.
09.04 Altraplen® Protein (formally known as Nutriplen® Protein) 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Used in cases where increased protein is required
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–6 years
09.04 Altrashot 
13.12 Aluminimum Salts 
09.05.02.02 Aluminium Hydroxide 

Specialist Recommendation

04.09.01 Amantadine Hydrochloride 

Capsules

Syrup - for patients with swallowing difficulties 

05.03.04 Amantadine Hydrochloride 
02.05 Ambrisentan 
05.01.04 Amikacin 

Hospital use only under microbiological advice

05.01.04 Amikacin Amikin®

Hospital use only under microbiological advice

02.02.03 Amiloride Hydrochloride 
03.01.03 Aminophylline IV 
05.01 Aminosalicylic Acid Granupas 4 g gastro-resistant granules

Hospital use only under microbiological advice

05.01 Aminosalicylic Acid 

Hospital use only under microbiological advice

02.03.02 Amiodarone 

Use current status at Place/Trust

Sandwell

Amber Initiation Specialist intiation supported by a RICaD

 Amiodarone RICaD-Sandwell only

Atrial fibrillation : Rhythm control should be used when:
symptomatic; under 65's; first time -lone AF; secondary to treated or corrected precipitant with congestive heart failure. Beta-blockers are first line, amiodarone should be used second line where structural heart disease is present

Check thyroid function and liver function every 6 months
Phototoxicity reactions possible - advise use of wide spectrum sunscreen.
Suspect pneumonitis if new or preogressive shortness of breath or cough develops

Following the policy - Items which should not routinely be prescribed in Primary Care. Patients who are established on Amiodarone should continue their prescriptions as normal

The guidance applies to new patients only

Wolverhampton

Amber Initiation

Walsall

Amber SC

 Dudley

Green

 

02.03.02 Amiodarone 
04.02.01 Amisulpride 

Supported by ESCA

04.03.01 Amitriptyline 

Tablets more cost effective than SF solution

Sugar Free solution £££££

04.07.03 Amitriptyline 

1st line

Low abuse potential, low cost

Off label use

04.07.04.02 Amitriptyline 
02.06.02 Amlodipine 
13.10.02 Amorolfine 5% 
03.13 Amoxicillin 

Hospital only

03.13 Amoxicillin 
03.13 Amoxicillin 
05.01.01.03 Amoxicillin 
05.01.01.03 Amoxicillin 
03.13 Amphotericin Fungizone®

Hospital only

03.13 Amphotericin Fungizone®
05.02 Amphotericin Fungizone ®
05.02 Amphotericin  
05.02 Amphotericin AmBisome ®
05.02 Amphotericin 
11.03.02 Amphotericin (eye) 
09.01.04 Anagrelide Xagrid®
10.01.03 Anakinra Kineret®

Specialist/hospital use only

In line with NICE

04.07.04.01 Analgesics Migraleve Pink®
08.03.04.01 Anastrozole 
02.08 Andexanet  
18 Andexanet alfa Ondexxya®

Use in line with NICE

05.02.04 Anidulafungin 
01.01.01 Antacid and oxetacaine suspension 150 ml 

Suspension

Specialist Use Only

14.05.03 Anti-D (Rh0) Immunoglobulin  This is commissioned by NHS England not CCG
14.05 Anti-D (Rh0) Immunoglobulin 

This is commissioned by NHS England not CCG 

08.02.02 Anti-human thymocyte immunoglobulin (rabbit)  Thymoglobuline® Commissioned by NHSE
Hospital only
01.07 Anusol® 

Anusol® - other brands also available

01.07.02 Anusol-HC® 
08.03.04.02 Apalutamide Erleada®

Use in line with NICE

02.08 Apixaban 


 

04.09.01 Apomorphine APO-Go®
04.09.01 Apomorphine Dacepton®
  • solution for injection in cartridge
  • solution for infusion (accepted July 2020)
A5.16 Appeel ® 

Available in 4 different applications

Preferred local option-5ml sachets & wipes pack of 30

Type of wound product is suitable for
Adhesive dressing or appliance removal where skin stripping, loss of skin integrity and
pain is a concern
•Sachet– suitable for larger dressing removal

•Wipes – ideal for adhesive around tubes

•Foam applicator – ideal for infants or use of the face

•Spray, single patient, multiple use product for all dressings and/or urinary sheath removal


Frequency of use
Use at each dressing change

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Should not be used when there is a known sensitivity to any of the ingredients
If in doubt, patch test a small area, prior to use
The product is flammable and should be used in a well ventilated area
Avoid use around, flames and sources of ignition

Rationale for inclusion in formulary
For pain free removal of dressings where fragile skin is a concern

11.08.02 Apraclonidine 0.5% eye drops 

For use on advice of specialist

11.08.02 Apraclonidine 1% SDU eye drops 

The only preservative free sympathomimetic

13.05.03 Apremilast  

In line with NICE

Use in adults is commissioned by CCGs

04.06 Aprepitant Emend®

For use with chemotherapy only

For chemo-related nausea and vomiting

Second-line agent in patients who have failed with 5HT3 antagonist

Hospital use only

02.11 Aprotinin Trasylol®
09.04 Aptamil Pepti® Junior 
19.12 Aquacel ®  Second choice to formulary alginate dressings.
Indications: sloughy, granulating wounds, moderate to heavy
exudate. Fibrous sterile sheet made of hydrocolloid fibers which
changes to a soft gel when in contact with exudate. Ensure dressing
is1cm larger than the wound as it reduces in size on gelling, and
cover with moisture retentive dressing
19.12 Aquacel ® Ribbon  Second line to formulary alginate dressings
Indications: sloughy, granulating wounds, moderate to heavy
exudate. Fibrous sterile sheet made of hydrocolloid fibers which
changes to a soft gel when in contact with exudate. Ensure dressing
is1cm larger than the wound as it reduces in size on gelling, and
cover with moisture retentive dressing
A5.02.04 Aquacel® 

Preferred local option

Type of wound product is suitable for
Moderate to heavy exudate, sloughy, necrotic or granulating wounds. Available in rope
for cavities

Duration dressing remains on wound before changing
Maximum 7 days

Frequency of dressing change
1-7 days depends on clinical need

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not suitable for dry wounds. Non dissolvable. Known product or component sensitivity
Do not cut

Rationale for inclusion in formulary
Aids debridement of slough or necrotic tissue
Remains intact so easily removed in one piece
Absorbs exudate which aids most wound healing facilitating atraumatic dressing change,
Cost effective

A5.03.03 Aquacel® Ag Extra 

Specialist recommendation only
Hydrofibre with silver
Type of wound product is suitable for
Management of clinically infected, sloughy, necrotic or granulating wounds with moderate to heavy exudate.
Moderate to highly exuding wounds.
Aquacel® Ag Extra can be used to break down biofilms
Requires a secondary dressing
Duration dressing remains on wound before changing
Dependent upon exudate 1 - 7 days
Frequency of dressing change
Dependent upon level of exudate and clinical presentation
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Should not be used on individuals who are sensitive to or have had an allergic reaction to the dressing or its components.
Not suitable for dry wounds.
No haemostatic properties.
Rationale for inclusion in formulary
Specialist antimicrobial product
Moderate to high exudate levels
Can be used to break down biofilms
Remains intact on wound bed and easily removable in one piece (non dispersible)

13.02.01 Aquadrate® Urea 10%  

Over the counter preparation suitable for self-care/purchase if appropriate

19.08 Aquaform  Alternative to GranuGEL®

Hydrogel: Clear viscose sterile gel
Aids autolytic debridement and removal of devitalised tissue.

Type of wound product is suitable for
Low exuding, necrotic or sloughy wounds

Duration dressing remains on wound before changing
Up to 3 days

Frequency of dressing change
1-3 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not suitable for heavily exuding wounds. Caution known product or component sensitivity.
Full thickness burns or infected wounds
Not for application to ischaemic wounds

Rationale for inclusion in formulary
Required for wound beds that need donation of moisture to rehydrate the wound bed and debride. Cost effective


Apply 5mm depth to prevent drying out. Single Use Only
Require secondary dressing – see below

EXUDATE SECONDARY DRESSING WITH HYDROGEL
None/dry wound Semi-permeable film to reduce moisture loss
Light Non-adherent dressing + tape or Mepore
Moderate Surgical absorbent + tape
06.02.02 Aqueous iodine  

Hospital use only.

01.06 Arachis Oil 
07.03.04 Arcing spring diaphragm  

Sizes 60-95mm (rising in 5mm)

02.08 Argatroban Exembol®
04.02.01 Aripiprazole  
  • Supported by ESCA
  • Use in Tourette's syndrome approved
04.02.02 Aripiprazole Abilify Maintena®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

08.01.05 Arsenic Trioxide Trisenox®

In line with NICE

05.04 Artemether > Riamet 
05.04.01 Artemether with Lumefantrine  Riamet®
05.04 Artesunate 
15.02 Articaine Hydrochloride with Adrenaline  Septanest®

Dental use only

09.06.03 Ascorbic Acid 
09.08.01 Asfotase alfa 

In line with NICE Highly Specialised Technology guidance 

04.07.01 Aspirin 

For gargling - topical analgesia

02.09 Aspirin (antiplatelet) 
02.09 Aspirin e/c 
05.03.01 Atazanavir 
05.03.01 Atazanavir with cobicistat Evotaz®

Blueteq /prior approval form

02.04 Atenolol 
08.02.03 Atezolizumab Tecentriq®

In line with NICE

Providers are NHS Trusts

04.04 Atomoxetine Strattera®

Please note that commissioning discussion is underway. However the present status is as follows:-


Amber SC  Age 6 and over - Solihull practices.  Supported with ESCA


Amber SC Age 16 and over - Birmingham practices.  Supported with ESCA

Red Age under 16 - Birmingham practices

Amber SC Supported with an ESCA - Sandwell & West Birmingham CCG for patients seen by the Black Country ADHD Services

02.12 Atorvastatin 
07.01.03 Atosiban Tractocile® For Specialist/ Hospital Use Only
05.04 Atovaquone 
15.01.05 Atracurium  

Hospital only

19.01 ATRAUMAN®  Type of wound product is suitable for
For flat granulating and epithelising wound for non to heavy exudate where adherence may occur. To be used as a primary dressing with a secondary for absorption.

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days, depending on levels of exudate

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity

Rationale for inclusion in formulary
Used to reduce adherence to wound bed. Most cost effective non adherent dressing.
Dressing impregnated with neutraltriglycerides to prevent penetration of granulation tissue.
Petroleum free.
A5.01.01 Atrauman® 

Preferred local option

Type of wound product is suitable for
For flat granulating and epithelising wound for non to heavy exudate where adherence may occur. To be used as a primary dressing with a secondary for absorption.

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days, depending on levels of exudate

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity

Rationale for inclusion in formulary
Used to reduce adherence to wound bed. Most cost effective non adherent dressing.
Dressing impregnated with neutraltriglycerides to prevent penetration of granulation tissue.
Petroleum free.

A5.03.03 Atrauman® Ag 

Specialist recommendation only

Non adherent Primary Dressing containing metallic silver

Type of wound product is suitable for
For clinically infected shallow, granulating wounds with low exudate. To be used as a primary dressing with a secondary for absorption.

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days, depending on levels of exudate

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity
Must be removed prior to x-ray, ultrasound, diathermy and MRI

Rationale for inclusion in formulary
Used to reduce adherence to wound bed with clinical signs of infection
Most cost effective non adherent dressing containing silver.
Dressing impregnated with neutral triglycerides to prevent penetration of granulation tissue.
Petroleum free.

02.06 Atropine 
15.01.03 Atropine 

For Myaesthenia Gravis only

15.01.03 Atropine 

HOSPITAL ONLY

15.01.03 Atropine  minijet®

HOSPITAL ONLY

15.01.03 Atropine 
21 Atropine 1%  
  • Oral use for drooling/secretions in neurological disease.

 

11.05 Atropine Sulphate  
11.05 Atropine Sulphate  
15.01.03 Atropine sulphate 
11.05 Atropine Sulphate Single Use 

Branded preservative free drops i.e. single use drops should be prescribed where available as manufactured 'specials' cost significantly more and don't have a product license

Restricted to patients needing preservative free

On specialist ophthalmologist recommendation

Used by glaucoma surgeons for neovascular glaucoma

08.01.05 Autologous anti-CD19-transduced CD3+ cells 

In line with NICE

09.01.04 Avatrombopag Doptelet®

In line with NICE

13.02.01 Aveeno cream® 

Green £££- Paediatrics only


Amber Initiation £££- Recommended by specialist for oncology use only

08.02.03 Avelumab Bavencio®

In line with NICE

Hospital ONLY

10.01.03 Avelumab Bavencio®

In line with NICE

07.04.05 Aviptadil 25 micrograms/Phentolamine 2mg Invicorp®

•Approved on formulary December 2017
•Specialist initiation
•3rd line after oral PDE-5 inhibitors failed and patient not responding to or intolerant of alprostadil
•To be reviewed within 12 months to assess alprostadil supply issues and patent expiry

08.02.04 Axicabtagene ciloleucel Yescarta®

In line with NICE

09.04.02 Aymes ActaSolve High Energy Powder sachets
  • Energy 195Kcal/ 100ml, Protein 4.1g/ 100ml
  • ACBS approved: for adults with short-bowel syndrome, intractable malabsorption, pre-operative preparation of undernourished patients, inflammatory bowel disease, total gastrectomy, bowel fistulae and disease-related malnutrition.
09.04.02 AYMES ActaSolve Smoothie Powder sachets
  • Powder 66 g reconstituted with 150ml water provides: protein 10.7 g, carbohydrate 41.5 g, fat 9.7 g, energy 1249 kJ (297 kcal)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula except dysphagia.
09.04 Aymes Shake 

Patient to be assessed using the malnutrition universal screening tool (MUST) before initiation of nutritional supplements.

09.04 Aymes® Complete 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Second line choice for 200ml ready-made. If powder is not tolerated or contraindicated

Patient to be assessed using the malnutrition universal screening tool (MUST) before initiation of nutritional supplements.

09.04 Aymes® creme 

Dessert style

Patient to be assessed using the malnutrition universal screening tool (MUST) before initiation of nutritional supplements

 

09.04 Aymes® Savoury 
  • More than 1kcal/ml and less than 5g protein/100mL
  • In line with food first
  • Not suitable for CKD 4-5, renal pts
  • Not suitable for lactose intolerance
  • Not suitable for bile acid malabsorption or fat maldigestion associated with biliary diseases/conditions
  • To be made up with whole milk
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula . Use with caution in child 1–6 years
08.01.03 Azacitidine Vidaza®

Commissioned by NHSE
Hospital only

01.05.03 Azathioprine 

Walsall

Amber Initiation Amber Initiation Walsall only 

Wolverhampton

Amber SC Amber Shared Care Wolverhampton only

ESCA Azathioprine (Wolverhampton only)

 Sandwell 

Amber SC Amber Shared Care Sandwell only

For use in Inflammatory Bowel Disease (IBD) as per effective shared care agreement

ESCA Azathioprine (Sandwell only)

 Dudley 

 Amber SC Amber Shared Care Dudley only

ESCA Azathioprine (Dudley only)

03.12 Azathioprine 

Sandwell 

Amber SC Amber Shared Care Supported by an ESCA

ESCA Sandwell only

Dudley

 Amber SC Amber Shared Care Supported by an ESCA

 ESCA Dudley only

Walsall

Not on formulary

Wolverhampton

Amber SC Amber Shared Care Supported by an ESCA

ESCA for Wolverhampton only

04.13 Azathioprine 

Specialist use only for neurological conditions

08.02.01 Azathioprine 

Commissioned by NHSE for post transplant patients.
Prescribing to remain with the specialist for this patient group
Injection-hospital only
Tablets/suspension for oncology/haematology

09.01.03 Azathioprine 

For the treatment of Auto immune haemolytic anaemia

Supported by an ESCA

10.01.03 Azathioprine 

Cytotoxic - do not crush or disperse in water.
Supported by an ESCA

13.05.03 Azathioprine Dermatology

Supported by an ESCA 

13.06.01 Azelaic acid 15% Finacea®
13.06.01 Azelaic Acid 20% cream Skinoren®

Use 2nd line to retinoids if benzoyl peroxide is not tolerated

12.02.01 Azelastine and fluticasone Dymista

Third line option for adults and children over 12 years with moderate to severe allergic rhinitis who have failed to respond to a steroid nasal spray with the addition of an oral antihistamine.
Follow treatment algorithm

11.04.02 Azelastine hydrochloride Optilast®
05.01.05 Azithromycin Azyter®
05.01.05 Azithromycin 

Green Tablets/ suspension -For Sexual Health (GUM Clinics) in Primary care only   

Amber Recommended IV-For Respiratory Indications

11.03.01 Azithromycin Azyter®

First line for ophthalmic chlamydia

05.01.02.03 Aztreonam 

Hospital use only under microbiological advice 

10.02.02 Baclofen 

Hospital use only

10.02.02 Baclofen 
21 Baclofen 
  • Hiccup 
  • Off-label use according to West Midlands Palliative Care Physicians Guidelines. 
13.02.01 Balneum Plus® 

Contains urea 5%, lauromacrogols 3%

Over the counter preparation suitable for self-care/purchase if appropriate

13.02.01.01 Balneum Plus® Bath Additive 

Over the counter preparation suitable for self-care/purchase if appropriate

05.03.01 Baloxavir marboxil 
01.05.01 Balsalazide Sodium Colazide ®

Sandwell 

Amber Recommended Amber Recommended -Sandwell only

Walsall

Green Green -Walsall only

Wolverhampton 

 Amber Initiation Amber Specialist Initiation continued in Primary Care -Wolverhampton only

 Dudley 

Amber SC Amber SC-Dudley only

ESCA Balsalazide (Dudley only)

10.01.03 Baricitinib Olumiant®

In line with NICE

13.05.03 Baricitinib Olumiant®

In line with NICE

09.04 Basecal® 
  • Over one year of age. Metabolic disorder pts
  • Also these are the only protein free (containing fat, carbohydrate, vitamins and minerals) powders aimed at children ≥1-year-old and adults with inborn errors of protein metabolism (particularly patients with urea cycle disorders and organic acidaemias). Basecal 100 and Basecal 200 are commonly added as an energy source in low protein module tube feeds. The dose will depend on energy requirements and tolerance to natural protein. It is commonly used in combination with a controlled amount of natural protein e.g. measured dose of standard enteral tube feed. It will help meet essential energy and nutrient requirements. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
08.02.02 Basiliximab Simulect®

Commissioned by NHSE for renal transplant patients
Hospital only

14.04 BCG intradermal vaccine  
14.04 BCG vaccine diagnostic agent 
03.02 Beclometasone and formoterol Fostair® NEXThaler®

How to use a NEXThaler Inhaler

03.02 Beclometasone and formoterol Fostair®

Licensed for both asthma and COPD

Asthma - use lowest effective dose. Consider step down at each review. Consider switch if appropriate

Alternative to Seretide Evohaler / Seretide 250 Accuhaler


 Note: when switching patients already using Beclometasone 250mcg CFC inhaler (e.g. Clenil), Fostair 100/6 can be prescribed and dose adjusted according to response


How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device

03.02 Beclometasone Dipropionate  Clenil Modulite®

May 2020 - see Clenil® Modulite® 100mcg (beclometasone): release of batch specific variation

How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device

 

12.02.01 Beclometasone Dipropionate 
03.02.03 Beclometasone/formoterol/glycopyrronium Trimbow NEXThaler®

How to use a NEXThaler Inhaler

03.02.03 Beclometasone/formoterol/glycopyrronium  
03.02.03 Beclometasone/formoterol/glycopyrronium  Trimbow 172/5/9 ®

Note:

-Two strengths of Trimbow available 

* Trimbow 172/5/9

* Trimbow 87/5/9

-Trimbow 172/5/9 is licensed for Asthma maintenance therapy only 

03.02.03 Beclometasone/formoterol/glycopyrronium  Trimbow 87/5/9 ®

Trimbow 87/5/9 is licensed for Moderate-to-severe chronic obstructive pulmonary disease and Asthma maintenance therapy

05.01.07 Bedaquiline 

Hospital use only under microbiological and Tuberculosis specialist advice 

03.04 Bee and Wasp Allergen Extracts Pharmalgen®
03.04.02 Bee venom extract 
08.02.02 Belatacept Nulojix® Not routinely commissioned by NHSE. NICE TA in progress
Hospital only
08.01.05 Belimumab Benlysta®

In line with NICE

02.12 Bempedoic acid 
02.12 Bempedoic acid with ezetimibe Nustendi®

In line with NICE

 

08.01.01 Bendamustine 

Commissioned by NHSE

02.02.01 Bendroflumethiazide 

2.5mg dose (higher doses are not indicated in hypertension)

A5.02.04 BeneHold TASA® 

Approved by APC April 2019

Hydrocolloid Range with film border

Type of wound product is suitable for
Lightly to moderately exuding wounds

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Only when necessary - up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use on third-degree burns. Should not be used on individuals who are sensitive to or have had an allergic reaction to the dressing or its components

Rationale for inclusion in formulary
Reduced dressing changes. More cost effective. Reduce use of more expensive foam dressings

03.04.02 Benralizumab 

 

 

03.14 Benralizumab Fasenra®

 

 

15.02 Benzocaine 20% Ultracare® Bubble Gum

Hospital only

13.06.01 Benzoyl Peroxide 

Starting with 2.5% and increasing to 5 % or 10%.

Titrating the strength reduces irritancy with Benzoyl Peroxide .

May bleach clothing.

Avoid in pregnancy.

13.06.01 Benzoyl Peroxide 3% with Clindamycin 1% Duac® Once Daily
13.06.01 Benzoyl Peroxide 5% with Clindamycin 1% Duac® Once Daily

Maybe more effective and aid compliance compared to twice daily products.

12.03.01 Benzydamine 0.15% 
01.07 Benzyl benzoate with bismuth oxide, bismuth subgallate, hydrocortisone acetate, peru balsam and zinc oxide 
05.01.01.01 Benzylpenicillin Benzathine 

For use by GUM & STD services only

05.01.01.01 Benzylpenicillin Sodium 

Green Injectable for suspected Meningitis in Primary Care

Red In secondary care for related indications

03.04.03 Berotralstat Orladeyo®

Use in line with NICE TA

04.06 Betahistine Dihydrochloride 

Ménière's disease, vertigo

09.08.01 Betaine  Cystadane® NHSE commissioned
06.03.02 Betamethasone 
11.04.01 Betamethasone  

For use on the advice of a specialist

11.04.01 Betamethasone  

For use on the advice of a specialist

12.01.01 Betamethasone  ear drops
13.04 Betamethasone (as Dipropionate) 0.05% with Salicylic Acid Diprosalic®

Potency - Potent

Dot Ointment contains 3% salicylic acid
Dot Scalp application contains 2% salicylic acid

13.04 Betamethasone (as Valerate) 0.025% Betnovate-RD®

Potency - Moderate
Dot Cream
Dot Ointment

13.04 Betamethasone (as Valerate) 0.1% Betnovate®

Potency - Potent
Dot Cream
Dot Ointment
Dot Scalp application

13.04 Betamethasone (as Valerate) 0.1% with Fucidic Acid 2% Fucibet®

Potency - Potent

Restricted to use in inflammatory conditions associated with an infection with confirmed susceptibility to the antimicrobial component.

Use for short periods - typically no more than one week

12.01.01 Betamethasone 0.1% with Neomycin 0.5% ear drops
11.04.01 Betamethasone 0.1% with Neomycin 0.5% eye drops 

Short term use only

13.04 Betamethasone Dipropionate 0.064% with Clotrimazole 1% Lotriderm®

Potency - Potent

Specialist initiation by Dermatology only

Restricted to use in inflammatory conditions associated with an infection with confirmed susceptibility to the antimicrobial component.

Use for short periods - typically no more than one week

12.02.01 Betamethasone Sodium Phosphate 
13.04 Betamethasone valerate medicated plaster Betesil®

Potency - Potent

Maximum treatment period 30 days

Available as a box of 4, size 7.5cm x 10cm medicated plaster

09.04 Betaquick® 
  • High-energy supplements: fat
  • 21% MCT emulsion, used orally and in cooking as an energy source for children and adults on a ketogenic diet
11.06 Betaxolol 

On Specialist Ophthalmologist Recommendation

11.06 Betaxolol 

On Specialist Ophthalmologist Recommendation

11.06 Betaxolol Unit Dose  

On Specialist Ophthalmologist Recommendation

07.04.01 Bethanechol Chloride Myotonine® For Specialist / Hospital Use Only
08.01.05 Bevacizumab 

Funding available through Cancer Drugs Fund (CDF) for indications listed in CDF list 

11.08.02 Bevacizumab intravitreal injection Avastin®
08.01.05 Bexarotene 
02.12 Bezafibrate 

Immediate release formulation

Modified release formulation

A5.02.05 Biatain® 

PODIATRY ONLY

Polyurethane foam dressing with bevelled edges

Type of wound product is suitable for
Moderately exuding wounds with signs of granulation, epithelialisation or slough.
Can be used as primary or secondary

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
Up to 7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use with oxidising solutions such as hydrogen peroxide
Full thickness burns
Surgical implantations

Rationale for inclusion in formulary
Simple to use on the foot and digits Can be cut to shape

08.03.04.02 Bicalutamide 
05.03.01 Bictegravir with emtricitabine and tenofovir alafenamide Biktarvy®
11.06 Bimatoprost 

2nd line

On Specialist Ophthalmologist Recommendation

11.06 Bimatoprost with Timolol Ganfort®

On Specialist Ophthalmologist Recommendation

13.05.02 Bimekizumab Bimzelx®

Use in line with NICE

12.03.05 Biotene Oralbalance® 

Dot Approved for ACBS conditions i.e. patients suffering from xerostomia (dry mouth) as a result of having or having undergone radiotherapy or sicca syndrome
Dot Palliative care
Dot Dental Practitioners

06.01.01.02 Biphasic Insulin Aspart 

BRANDS

  • NovoMix 30 FlexPen
  • NovoMix 30 Penfill
06.01.01.02 Biphasic Insulin Lispro 

BRANDS

  • Humalog Mix25
  • Humalog Mix25 KwikPen
  • Humalog Mix50
  • Humalog Mix50 KwikPen
06.01.01.02 Biphasic Isophane Insulin Insuman Comb®

Insuman comb 25

Insuman comb 50

 

 

06.01.01.02 Biphasic Isophane Insulin 

BRANDS

  • Humulin M3
  • Humulin M3 KwikPen
01.06.02 Bisacodyl 

5mg E/C tablets

10mg Suppository

12.04 Bismuth Iodine Paraffin Paste  BIPP®
12.04 Bismuth Subnitrate and Iodoform Paste for Gauze 
01.03.03 Bismuth subsalicylate Pepto Bismol®
02.04 Bisoprolol 
02.06 Bivalirudin Angiox®
02.08 Bivalirudin  Angiox®
08.01.02 Bleomycin 

Commissioned by NHSE
Hospital only

13.07 Bleomycin intra-lesiona
08.02.03 Blinatumomab Blincyto®

In line with NICE

12.03.01 Bonjela Junior® 

From 3 month of age

08.01.05 Bortezomib Velcade®

In line with NICE

02.05.01 Bosentan 
08.01.05 Bosutinib Bosulif®

In line with NICE
Hospital only-NHSE commissioned

20 Botulinium toxin 100 units for achalasia 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

01.02 Botulinium Toxin A 
04.12 Botulinum neurotoxin type A Xeomin®

In line with NICE

04.07.04.02 Botulinum Toxin Type A 

For hospital use only

Use in line with NICE 

13.12 Botulinum toxin type A   For hyperhidrosis (commissioning discussion to take place).
14.04 Botulism antitoxin 

Hospital only

09.04.01 Bread 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Essential protein-free basic products. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein. 1 slice ordinary bread = 4g protein and is not allowed in low protein diets
08.01.05 Brentuximab vedotin Adcetris®

In line with NICE

08.01.05 Brigatinib Alunbrig®

In line with NICE

Providers - NHS hospital trusts

13.06 Brimonidine 3mg/g Mirvaso® For facial erythema in rosacea
11.06 Brimonidine Tartrate 

On Specialist Ophthalmologist Recommendation

11.06 Brimonidine Tartrate 0.2% with Timolol 0.5% Combigan®

Avoid in patients receiving verapamil and in those with bradycardia, heart block, uncontrolled heart failure, asthma or COPD

On Specialist Ophthalmologist Recommendation

11.06 Brinzolamide 1% with Timolol 0.5%  Azarga®

On Specialist Ophthalmologist Recommendation

11.06 Brinzolamide 10mg/ml 

On Specialist Ophthalmologist Recommendation

11.06 Brinzolamide 10mg/ml and brimonidine tartrate 2mg/ml Simbrinza®

On Specialist Ophthalmologist Recommendation

Third line option, after prostaglandin analogues (1st line) and beta-blocker/ prostaglandin analogue plus beta-blocker (2nd line)

For patients in whom monotherapy provides insufficient IOP reduction.

11.06 Brinzolamide 10mg/ml with Timolol 5mg/ml 

2nd/3rd line

On Specilaist Ophthalmologist Recommendation

04.08.01 Brivaracetam Briviact®

•Initiation by Tertiary Epilepsy Specialist only.
•For adjunctive therapy in the treatment of partial-onset seizures with or without secondary generalisation in adult and adolescent patients from 16 years of age with severe refractory epilepsy warranting tertiary specialist input for patients who have tried three or more AEDs. The patient has used levetiracetam and has documentation of intolerance and patient is using a third line agent (perampanel, zonisamide, lacosamide, eslicarbazepine) which would be replaced by brivaracetam

Supported by an ESCA

04.08.01 Brivaracetam Briviact ®
10.01.03 Brodalumab Kyntheum®

In line with NICE

13.05.02 Brodalumab Kyntheum®

Hospital use only

In line with NICE

11.08.02 Brolucizumab  Beovu®

In line with NICE

06.07 Bromocriptine 
01.05.02 Budesonide Jorveza®

In line with NICE

01.05.02 Budesonide Cortiment®
01.05.02 Budesonide Entocort®
  • Enema
  • CR/MR Capsules
01.05.02 Budesonide Budenofalk®
  • Rectal foam Enema
  • Gastro-resistant Capsules
  • Granules

 

03.02 Budesonide Easyhaler®

 

How to use an Easyhaler Inhaler

03.02 Budesonide Pulmicort Turbohaler®

 

How to use a Turbohaler Inhaler

 

03.02 Budesonide 
03.02 Budesonide Pulmicort Respules®
03.02 Budesonide 
  • Dry powder Inhaler
  • Easyhaler
  • Prescribe by brand

How to use a Turbohaler Inhaler

How to use an Easyhaler Inhaler

03.02 Budesonide and Formoterol Fobumix Easyhaler®

How to use an Easyhaler Inhaler

03.02 Budesonide and Formoterol 100/6 Symbicort Turbohaler®
  • For treatment of asthma only
  • Use lowest effective dose. Consider step down at each review.
  • Prescribe by brand to ensure patient receives the device they are used to.
    How to use a Turbohaler Inhaler
03.02 Budesonide and Formoterol 200/6 Symbicort Turbohaler®

For Asthma, maintenance and reliever therapy in adults and adolescents (12 years and older) with mild asthma


How to use a Turbohaler Inhaler

02.02.02 Bumetanide 
15.02 Bupivacaine 

Hospital only

15.02 Bupivacaine and Adrenaline 

Hospital only

15.02 Bupivacaine hydrochloride Marcain®

Hospital only

15.02 Bupivacaine Hydrochloride with Glucose Marcain Heavy®

Hospital only

15.02 Bupivacaine with Fentanyl 

Hospital only

04.10.03 Buprenorphine 

For use under specialist addiction services

21 Buprenorphine  
  • Recommend 7-day patch.
  • With specialist recommendation, first line choice if renal failure and patient requires a strong opioid.

     

04.07.02 Buprenorphine Patch 

ONCE A WEEK patch (7-day patch)

For specialist initiation: specialist pain clinics, palliative care and for patients with swallowing difficulties

Patches should be prescribed by BRAND

04.07.02 Buprenorphine Patch Transtec®

TWICE WEEKLY patch

For specialist initiation: specialist pain clinics, palliative care and for patients with swallowing difficulties

Patches should be prescribed by BRAND

04.07.02 Buprenorphine sublingual tablet 

Specialist use only

For use in opioid dependence, see section 4.10.3

04.03.04 Bupropion  Hospital use only
04.10.02 Bupropion Hydrochloride Zyban®
08.03.04.02 Buserelin 

Hospital only

Listed in Chapter 6 for other indications

04.01.02 Buspirone Hydrochloride 

£££££

Second line

08.01.01 Busulfan 

Commissioned by NHSE
Concentrate for infusion-hospital only

03.04.03 C1- esterase Inhibitor Berinert®
03.04.03 C1- esterase Inhibitor Cinryze®
08.01.05 Cabazitaxel Jevtana®

In line with NICE

06.07 Cabergoline 

Amber Recommended - Cabaser

Amber Recommended - Dostinex

05.03.01 Cabotegravir Vocabria®

In line with NICE

08.01.05 Cabozantinib Cabometyx®

In line with NICE

13.14.03 Cade oil 12% w/w & salicylic acid 6% w/w in emulsifying ointment 
03.05.01 Caffeine citrate 
09.04.01 Cake, biscuits and snacks 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Important protein-free foods to provide important energy, assist dietary adherence and provide variety when natural protein tolerance is very limited. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein
13.03 Calamine aqueous cream 

Over the counter preparation suitable for self-care/purchase if appropriate

13.03 Calamine lotion 

Over the counter preparation suitable for self-care/purchase if appropriate

09.05.01.01 Calcichew® (calcium salts) 
13.05.02 Calcipotriol 50mcg/g  

Dot Ointment
Dot Scalp solution £££

13.05.02 Calcipotriol 50mcg/g with betamethasone 0.5mg/g Enstilar®

•The recommended treatment period is 4 weeks
•Maximum 15g per day
•Excipients include liquid paraffin and butane
Extremely flammable aerosol

13.05.02 Calcipotriol 50micrograms/g with Betamethasone 0.05% Dovobet®

•4 weeks therapy then assess
Maximum 15g per day or 100g per week.
Step down to calcipotrol oint as per NICE CG153

13.05.02 Calcipotriol 50micrograms/g with betamethasone 0.05% Dovobet®

Dot Scalp psoriasis: usual duration of treatment is 4 weeks
Dot Mild to moderate plaque psoriasis, apply once daily to max. 30% of body surface (max. 15 g daily) for 8 weeks

06.06 CALCITONIN 

CALCITONIN (SALMON)/SALCATONIN - Red

CALCITONIN SALMON/ CALCITONIN - Red

06.06.01 Calcitonin (salmon) / Salcatonin 

Injection

Nasal spray

For hospital use only

06.06 Calcitriol 
09.06.04 Calcitriol 
13.05.02 Calcitriol 3micrograms/g Silkis®

Specialist recommendation only.
For delicate areas, face & flexures.

09.06.04 Calcium and vitamin D preparations 

Please follow Optimise Rx for most cost effective brand

09.05.01.01 Calcium Chloride (parenteral) 

Hospital only

09.05.01.01 Calcium Gluconate 

Hospital only

08.01 Calcium Levofolinate Isovorin® For hospital use only in chemotherapy induced mucositis and myelosuppression
09.05.02.02 Calcium salts  

Specialist Recomendation

09.04 Calogen® 
  • High-energy supplements: fat
  • Used as a source of LCT, as an energy supplement and additive to feed to enhance energy density
  • Does not contain protein
  • Also this is the only LCT fat source that can be used as a fat energy source in patients with organic acidaemias e.g. propionic acidaemia and methyl malonic acidaemia and urea cycle disorders. It may also be used as part of a modular feed or protein-free energy source. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat (or fat and carbohydrate) supplement. Liquid supplements
06.01.02.03 Canagliflozin 

For treating Type 2 diabetes  in line with NICE, and chronic kidney disease.

Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis) 

06.01.02.03 Canagliflozin/Metformin Vokanamet®
02.05.05.02 Candesartan cilexetil 
02.06 Cangrelor 
04.08.01 Cannabidiol  Epidyolex®

In line with NICE

13.09 Capasal® 

Over the counter preparation suitable for self-care/purchase if appropriate

08.01.03 Capecitabine 

Commissioned by NHSE

12.03.01 Caphosol® 

Oncology and Haematology use only

09.01.04 Caplacizumab Cablivi®

In ine with NICE

Providers are NHS Specialist Centres

05.01.09 Capreomycin 

Hospital use only under Microbiological/Tuberculosis advice only

04.07.03 Capsaicin 

For local neuropthic pain

ONLY strength licensed for post-herpetic neualgia and diabetic peripheral polyneuropathy

For other strength, see section 10.3.2

Please note that capsaicin 8% patches are non-formulary

06.01.02.03 Capsaicin 

Green 

  • Axsain
  • Zacin

Red

  • Qutenza - PAIN TEAM ONLY
10.03.02 Capsaicin cream 0.025% 

Tier 2

Topical capsaicin 0.025% cream(Zacin) should be considered as an adjunct to core treatments for knee or hand osteoarthritis. [NICE 2008]

10.03.02 Capsaicin cream 0.075% 

See Chapter 7.4.3 for neuropathic pain

02.05.05.01 Captopril 

For existing patients and Paediatric use

04.02.03 Carbamazepine 

On specialist advice

04.07.03 Carbamazepine 

For the treatment of trigeminal neuralgia only

Baseline LFTs,FBC and U & Es- then 6 monthly

04.08.01 Carbamazepine 

Tablets

M/R tablets

SF liquid

Suppositories

Tegretol is the preferred brand for new patients however please ensure that existing patients are maintained on a specific manufacturers brand

MHRA Advice
Patients being treated for epilepsy should be maintained on a specific manufacturer's product

06.02.02 Carbimazole 


Counselling: warn patient to tell doctor immediately if sore throat, mouth ulcers, bruising, fever, malaise or non-specific illness develops

03.07 Carbocisteine 

 Prescribe as 375 mg caps. Avoid prescribing 750 mg caps

  • Capsules
  • Oral Solution
A5.02.08 CarboFlex® 

Specialist recommendation only
Preferred local option

Odour absorbent wound contact dressings containing activated charcoal
Type of wound product is suitable for
For the management of moderate to heavily exuding malodorous wounds including fungating
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
As exudate level determines
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to the dressing or its components
As soon as CarboFlex® becomes contaminated with exudate, odour control diminishes
The underlying cause of wound odour should be identified prior to commencement of product
Rationale for inclusion in formulary
CarboFlex® is a layered dressing to provide higher levels of fluid handling
On shallow or cavity wounds with moderate to heavy levels of exudate

11.08.01 Carbomers Clinitas Gel®

Clinitas Gel does not have benzalkonium chloride (BAK) as a preservative. It is preserved with cetrimide.

07.01.01 Carboprost Hemabate® For Specialist/ Hospital Use Only
09.04 Carbzero® 
  • High-energy supplements: fat
  • 20% LCT emulsion, used as an energy source for children and adults on a ketogenic diet, may be used orally or in cooking
  • For use in ketogenic diets. Long chain triglyceride liquid emulsion used as a milk replacement (when diluted) for some patients with PKU on very low protein diets who cannot tolerate other low protein milk replacements. It will help meet essential energy requirements. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
09.04 Carbzero® 
  • High-energy supplements: fat
  • 20% LCT emulsion, used as an energy source for children and adults on a ketogenic diet, may be used orally or in cooking
  • For use in ketogenic diets. Long chain triglyceride liquid emulsion used as a milk replacement (when diluted) for some patients with PKU on very low protein diets who cannot tolerate other low protein milk replacements. It will help meet essential energy requirements. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
08.01.05 Carfilzomib Kyprolis®

In line with NICE

11.08.01 Carmellose 0.5% SDU 

Reserve single use eye drops for patients who have known hypersensitivity to preservatives

11.08.01 Carmellose 1% multi (Moorfields) 
08.01.01 Carmustine  Gliadel®

Commissioned by NHSE
Hospital only

09.09 Carobel, Instant® 
  • Used as a feed thickener for infants with GORD and in children with swallowing issues who require thickened fluids
  • Used in dysphagic patients or those requiring thickened feeds
  • For thickening feeds in the treatment of vomiting
02.04 Carvedilol 
05.02.04 Caspofungin 
05.01.02.01 Cefalexin 
05.01.02.01 Cefazolin 

Hospital use only under microbiological advice

05.01.02.01 Cefepime 

Hospital use only under microbiological advice

05.01.02.01 Cefiderocol Fetcroja®

Hospital use only under microbiological advice. Blueteq applications required 

05.01.02.01 Cefixime Suprax®

Hospital use only under microbiological advice 

05.01.02.01 Cefotaxime 

Hospital use only under microbiological advice 

03.13 Ceftazidime 

Hospital only

05.01.02.01 Ceftazidime 

RedHospital use only under microbiological advice 

Green Under OPAT sheme

05.01.02.01 Ceftazidime with avibactam 

Hospital use only under microbiological advice 

05.01.02.01 Ceftobiprole Zevtera®

Hospital use only under microbiological advice 

05.01.02.01 Ceftolozane with tazobactam 

Hospital use only under microbiological advice 

05.01.02.01 Ceftriaxone 

GreenInjectable - Green under OPAT scheme in Primary Care

Secondary care - for specific indications 

03.13 Cefuroxime 

Hospital only

05.01.02.01 Cefuroxime Oral and IV
11.03.01 Cefuroxime 

Hospital only

11.08.02 Cefuroxime 

Hospital only

10.01.01 Celecoxib Celebrex®

COX-2 inhibitor

Not routinely recommended as first or second-line treatment choice.

Consider the use of a standard NSAID and a PPI (choose the agent with the lowest acquisition cost) ahead of a COX-2 inhibitor.

CVD risk assessment

Supported by RICaD-in development

A5.08.07 Cellona 

Preferred local option

Specialist recommendation only
Sub compression wadding bandage to pad and shape a limb prior to compression therapy
Type of wound product is suitable for
Provides padding for larger limbs under compression.
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
Daily up to weekly dependant on exudate and oedema management.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Advised not to apply directly to skin as can cause irritation.
Rationale for inclusion in formulary
Cost effective for use in larger quantities when used in lymphoedema management.

08.01.05 Cemiplimab Libtayo®

In line with NICE

08.01.05 Cenegermin Oxervate®

In line with NICE

04.08.01 Cenobamate Ontozry®

In line with NICE

09.04.01 Cereals 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Essential protein-free basic products. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein. 2 regular Weetabix = 4.5g protein and this protein amount is more than the amount of protein that may be tolerated
08.01.05 Ceritinib Zykadia®

In line with NICE

10.01.03 Certolizumab Pegol Cimzia®

Specialist/hospital use only

Available via Home Care

12.01.03 Cerumol® 
03.04.01 Cetirizine Hydrochloride 

OTC preparation suitable for self-care/purchase if appropriate

  • Capsules
  • Oral Solution- Green for children and those unable to swallow
A5.13 Cetraben pump cream 

Emollient containing white soft paraffin and light liquid paraffin
Type of wound product is suitable for
For inflamed, dry, chapped skin
Frequency of use
Daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Treatment of dry skin
Dermatology approved

13.02.01 Cetraben® 

More greasy option

Over the counter preparation suitable for self-care/purchase if appropriate

08.01.05 Cetuximab Erbitux®

In line with NICE

04.01.01 Chloral Hydrate 500mg in 5mL  For hospital use only.
Unlicensed special.
08.01.01 Chlorambucil 

Commissioned by NHSE

05.01.07 Chloramphenicol 

For specialist use only

11.03.01 Chloramphenicol 
  • 0.5% eye drops - First line
  • 0.5% Minims (SDU) for patients who require preservative free
  • 1% eye ointment
12.01.01 Chloramphenicol  

Only with positive culture/sensitivity data

04.01.02 Chlordiazepoxide 

Adjunct in acute alcohol withdrawal

04.10.01 Chlordiazepoxide 

Adjunct in acute alcohol withdrawal

13.11.02 Chlorhexidine gluconate 0.015% with cetrimide 0.15% Tisept®
13.11.02 Chlorhexidine gluconate 0.05% Unisept®
12.03.04 Chlorhexidine gluconate 0.2% 
12.03.04 Chlorhexidine gluconate 1% 
13.11.02 Chlorhexidine gluconate 4% 
13.11.02 Chlorhexidine gluconate 4% 
13.11.02 Chlorhexidine gluconate preparations 
12.02.03 Chlorhexidine Hydrochloride 0.1%, Neomycin Suphate 0.5% Naseptin®
  • Contains arachis (peanut) oil, not siutable for patients with allergy to peanuts
  • Patients with soya allergy should also avoid Naseptin®
08.01.05 Chlormethine gel Ledaga®

Use in line with NICE

05.04 Chloroquine 

Green for treatments NHS funded

03.04.01 Chlorphenamine 

OTC preparation suitable for self-care/purchase if appropriate

  • Oral Solution- for children and those unable to swallow
03.04.01 Chlorphenamine maleate 
04.02.01 Chlorpromazine 

Not to be used for psychiatric / anxiolytic purposes in Primary Care

04.02.01 Chlorpromazine 

Supported by an ESCA

04.06 Chlorpromazine hydrochloride 

For nausea

Hyperemesis in pregnancy (off label use)

02.02.01 Chlortalidone 
14.04 Cholera vaccine Dukoral®

Via travel vaccine service

12.03.01 Choline Salicylate 

Provides short term analgesic effects. Avoid excessive use or use under dentures as may itself cause ulceration


For patients over 16 years only

06.05 Choriogonadotropin Alfa Ovitrelle®
A5.04.02 CICA-CARE 

Specialist recommendation only
Silicone sheet for scar treatment
Type of wound product is suitable for
Not for use on open wounds- to be applied on healed scar only.
This is not a dressing but a scar treatment
Duration dressing remains on wound before changing
23 hours
Frequency of dressing change
Daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use on open or infected wounds. Do not use on skin affected by acne. Discontinue use if a rash or itching occur.
Rationale for inclusion in formulary
Scar therapy
Silicone sheets have been shown to soften, flatten scarring aiding movement, nerve sensations and function. Self adherent, Re-usable

01.05.03 Ciclosporin 

Treatment of ulcerative colitis - for specialist use only

MHRA specify the ciclosporin must be prescribed and dispensed by brand as bioavailabilty differences exist between brands

 

04.13 Ciclosporin 

Specialist use only for neurological conditions

08.02.02 Ciclosporin Neoral®,Sandimmun®

Prescribe by brand

Post-transplant immunosuppression is comissioned by NHSE and all prescribing should remain with the specialist

Red Traffic Light  Post transplant- if prescribing is NOT established with GP before 1st April 2013


  Post transplant - if prescribing IS established with GP before 1st April 2013

08.02.02 Ciclosporin  Hospital only
10.01.03 Ciclosporin 

Prescribe and dispense by brand
Supported by an ESCA

13.05.03 Ciclosporin 

Supported by an ESCA 

11.99.99.99 Ciclosporin 1mg/mL Ikervis®
  • Specialist Opthalmologist Initiation
  • Treatment of severe keratitis in adult patients with dry eye disease, which has not improved despite treatment with tear substitutes
  • In line with NICE
11.99.99.99 Ciclosporin 1mg/ml eye drops, emulsion Verkazia®
  • Specialist Opthalmologist Initiation
  • Treatment of severe vernal keratoconjunctivitis (VKC) in children from 4 years of age and adolescents
11.99.99.99 Ciclosporin 2mg/g  Optimmune®
05.03.02.02 Cidofovir  
01.03.01 Cimetidine 
09.05.01.02 Cinacalcet Mimpara®

NHSE funded for dialysis only

All prescribing retained by secondary care

In line with NICE TA117

04.06 Cinnarizine 
05.01.12 Ciprofloxacin 
05.01.12 Ciprofloxacin 
11.03.01 Ciprofloxacin 

Specialist Ophthalmologist recommendation (Corneal consultant)

For existing patients only on consultant ophthalmologist advice

12.01.01 Ciprofloxacin 0.3% drops 

Off label use of eye drops
Specialist recommendation only

12.01.01 Ciprofloxacin 2mg/ml (0.2%) Ear Drops Cetraxal®

Licensed product for topical treatment of acute otitis externa (AOE)

15.01.05 Cisatracurium Nimbex®

Hospital only

08.01.05 Cisplatin  Commissioned by NHSE
Hospital only
04.03.03 Citalopram 

4 drops (8 mg) is equivalent in therapeutic effect to 10mg tablet

Risk of QT prolongation

04.03.03 Citalopram 

Risk of QT prolongation

03.09 Citric acid oral presentations
08.01.03 Cladribine  NHSE does not routinely commission this drug
Hospital only
08.02.04 Cladribine Mavenclad®

In line with NICE

Hospital only

05.01.05 Clarithromycin 
05.01.05 Clarithromycin 
06.04.01.01 Climanor® 
05.01.06 Clindamycin 

GreenUse 150mg capsules 

Black300mg capsules are Non-formulary 

05.01.06 Clindamycin  300mg/2ml
07.02.02 Clindamycin Dalacin®
13.06.02 Clindamycin 

Specialist initiation-12 week course.

13.06.01 Clindamycin 1% Dalacin T®
A5.08.03 CliniFast 

Preferred local option

Elasticated Sub bandage lining

Type of wound product is suitable for
To be used under retention and compression bandages when conformity is required
Can be used for wet/dry wrapping.

Duration dressing remains on wound before changing
As required

Frequency of dressing change
As required

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Ensure the correct size for a limb is selected

Rationale for inclusion in formulary
Cost effective choice when conformity to a limb is required

19.32 CLINIPORE® 
A5.07.03 Clinipore® 

Preferred local option

Permeable non woven, synthetic adhesive tape for securing bandages

Frequency of dressing change
Determined by wound type and dressing change

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None listed

Rationale for inclusion in formulary
Available on drug tariff, cost effective and evaluated as meeting the requirements of a tape including adherence.

A5.02.08 CliniSorb® 

Specialist recommendation only

Preferred local option

Odour absorbent charcoal dressing

Type of wound product is suitable for
Malodourous wounds such as fungating wounds

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not indicated as a primary dressing in dry wounds
Store at room temperature
Exudate levels will reduce the effectiveness of the charcoal

Rationale for inclusion in formulary
CliniSorb® is an activated charcoal dressing which adsorb toxins removing malodour from the wound
Can be cut to size
Cost effective

06.04.01.01 Clinorette®  
04.08.01 Clobazam 

On specialist advice

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particluar manufacturer's product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

13.04 Clobetasol Propionate 0.05% Dermovate®

Potency - very potent

Short term use only unless under supervision of a dermatologist

Dot Cream
Dot Ointment
Dot Scalp application

13.04 Clobetasone Butyrate 0.05% Eumovate®

Potency - moderate
Dot Cream
Dot Ointment

08.01.03 ClofarabineRestricted Item  Evoltra® Funding may be available from cancer drugs fund
Hospital only
05.01.10 Clofazimine 

Hospital use only under microbiological and Tuberculosis specialist advice 

06.05 Clomifene citrate 
04.03.01 Clomipramine 

An alternative to SSRIs in obsessive-compulsive disorder (OCD)

04.08.01 Clonazepam 

On specialist advice

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particluar manufacturer's product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

21 Clonazepam  
  •  Off-label use according to West Midlands Palliative Care Physcians Guidelines. 
02.05.02 Clonidine Hydrochloride Catapres®


Use only on advice of specialist

06.04 Clonidine Hydrochloride 
02.05.02 Clonidine Liqiud 
02.09 Clopidogrel 
07.02.02 Clotrimazole 
13.10.02 Clotrimazole 1% cream 
  • cream
  • powder
  • solution  
12.01.01 Clotrimazole solution Canesten®

Only with positive culture/sensitivity data

04.02.01 Clozapine 

Specialist initiation and maintenance only

02.08.02 CoaguChek XS PT Test PST  

Sandwell only -Red

13.14.03 Coal tar BP 10% w/w in YSP 
13.14.03 Coal tar BP 2% w/w in YSP 
13.14.03 Coal tar BP 5% w/w in YSP 
13.09 Coal Tar Extract 5% (Alcoholic) Alphosyl 2 in 1®

Over the counter preparation suitable for self-care/purchase if appropriate

13.05.02 Coal tar lotion 5% Exorex®
13.05.02 Coal Tar Solution 2.5%, Arachis (peanut) Oil extract of Coal Tar 7.5%, Tar 7.5%, Cade Oil 7.5%, Liqiud Paraffin 35% Polytar Emollient®

Contains peanut oil

13.14.02 Coal tar solution BP 3.3% w/w and propylene glycol 20% w/w in Synalar® gel 
13.14.02 Coal tar solution BP 5% w/w in betamethasone valerate 0.025% w/w ointment 
13.14.03 Coal tar solution BP 6% w/w & salicylic acid 6% w/w in Ung. Merck 
13.14.03 coal tar solution BP 6% w/w / salicylic acid 2% w/w in emulsifying ointment 
05.01.01.03 Co-amoxiclav 
05.01.01.03 Co-amoxiclav 
19.48 COBAN 2 LITE®  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective. Provide compression equivalent to multi-layer bandaging yet have the advantage of only two layers allowing patients to wear shoes increasing patient comfort and concordance.
19.48 COBAN 2®  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective. Provide compression equivalent to multi-layer bandaging yet have the advantage of only two layers allowing patients to wear shoes increasing patient comfort and concordance.
A5.08.08 Coban® & Coban® Lite 

Preferred local option

Two layer compression system available in full and reduced compression (Coban® Lite). Comprises of a latex free foam padding and cohesive bandage.
Type of wound product is suitable for
Treatment of venous and mixed aetiology leg ulcers
Duration dressing remains on wound before changing
1 to 7 days
Frequency of dressing change
Daily up to weekly dependant on exudate and oedema management.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Arterial disease
Not to be used with other padding or wadding
Rationale for inclusion in formulary
Two layer compression kit, Once applied the two layers form a band to become a single
layer bandage.
Bandage technique can be adapted to reduce forefoot oedema (Extra training required)

04.09.01 Co-beneldopa 

Capsules

M/R capsules

Dispersible tablets

05.03.01 Cobicistat Tybost ®
15.02 Cocaine 

Hospital only:
Dot 10% solution
Dot 25% paste
Dot 5% nasal solution

15.02 Cocaine with Adrenaline 

Hospital only

04.09.01 Co-careldopa 

Tablets

M/R tablets

04.09.01 Co-Careldopa and Entacapone Stalevo
12.01.01 Cochlear implants 

In line with NICE

Providers -  NHS hospital trusts

13.14.06 Coconut oil 25% w/w in emulsifying ointment 
13.06.02 Co-Cyprindiol 2000/35 

Prescribe as GENERIC

01.06.02 Co-danthramer 

Capsules 25/200, 75/1000

Co-danthramer strong preferred as per palliative care formulary guidance

 

01.06.02 Co-danthrusate 

Capsules 50/60

 

21 Co-danthrusate / Co-danthramer / Danthron 
  •  Specialist initiation ONLY due to risk of severe side-effects

 

01.04.02 Codeine 

Avoid long term use due to possible dependence

04.07.02 Codeine phosphate 
04.07.02 Codeine Phosphate 

Tablets

25mg/5ml syrup

Use with caution in patients aged over 65

Contraindicated in children below the age of 12

10.01.04 Colchicine 

acute gout

09.06.04 Colecalciferol oral 

Please follow Optimise Rx for most cost effective brand

Please see guidance below to support prescribing

Please prescribe generically as listed below

Oral Capsules or Tablets
Colecalciferol 800unit capsules
Colecalciferol 800unit tablets
Colecalciferol 1,000unit capsules
Colecalciferol 1,000unit tablets
Colecalciferol 3,200unit capsules
Colecalciferol 4,000unit tablets
Colecalciferol 20,000unit capsules
Colecalciferol 25,000unit tablets
Colecalciferol 40,000unit capsules

Oral Solution
Colecalciferol 2,740units/ml oral drops sugar free
Colecalciferol 10,000units/ml oral drops sugar free
Colecalciferol 10,000units/ml oral solution sugar free
Colecalciferol 15,000units/5ml oral solution
Colecalciferol 25,000units/1ml oral solution unit dose ampoules sugar free
Colecalciferol 50,000units/1ml oral solution unit dose ampoules sugar free


Licensed brands currently available (updated March 2017)
Aviticol 800 IU Capsules
Aviticol 1,000 IU Capsules (Listed in the Drug Tariff)
Aviticol 20,000 IU Capsules

Desunin 800 IU Tablets (Listed in the Drug Tariff)
Desunin 4,000 IU Tablets (Listed in the Drug Tariff)

Fultium-D3 800 IU Capsules (Listed in the Drug Tariff)
Fultium-D3 3,200 IU Capsules (Listed in the Drug Tariff)
Fultium-D3 20,000 IU Capsules (Listed in the Drug Tariff)
Fultium-D3 2740 IU/ml oral drops, solution (Listed in the Drug Tariff)

InVita D3 800 IU Capsules
InVita D3 2,400 IU/ml oral drops, solution
InVita D3 25,000 IU oral solution (Listed in the Drug Tariff)
InVitaD3 50,000 IU oral solution (Listed in the Drug Tariff)

Plenachol 20,000 IU Capsules
Plenachol 40,000 IU Capsules (Listed in the Drug Tariff)

Stexerol-D3 1,000 IU Tablets (Listed in the Drug Tariff)
Stexerol-D3 25,000 IU Tablets (Listed in the Drug Tariff)

STRIVIT-D3 800 IU Capsules

THORENS 10 000 IU/ml oral drops, solution (Listed in the Drug Tariff)
THORENS 25 000 IU/2.5 ml oral solution

01.09 Colesevelam Cholestagel®

Supported by a RICaD (in development)

02.12 Colesevelam Cholestagel®
02.12 Colestipol  Colestid®

 

01.09 Colestyramine  

Supported by a RICaD (In development)

 

02.12 Colestyramine 
05.01.07 Colistimethate 

Hospital use only under microbiological advice 

05.01.07 Colistimethate Promixin®
05.01.07 Colistimethate for nebulisation Colomycin®
05.01.07 Colistimethate for nebulisation 
05.01.07 Colistimethate inhaler Colobreathe®
03.13 Colistimethate sodium 

Commissioned by NHS England for Cystic Fibrosis only


 
 

10.03.01 Collagenase clostridium histolyticum Xiapex®

In line with NICE

01.01.01 Co-magaldrox 

Sugar free suspension


Mucogel is the most cost-effective brand


Low sodium content


Use with caution in patients with renal impairment as aluminium and magnesium accumulate

06.04.01.01 COMBINED CYCLICAL HRT 

BRANDS

  • Elleste-Duet
  • Prempak-C
19.38 COMFIFAST®  Red (small limb)
Green (medium limb)
Blue (large limb)
Yellow (child’s trunk or very large limbs)
Beige (adults trunk)
Elasticated viscose stockinette indicated for retention of dressings on difficult parts of the body or covering wet wraps such as paste bandages. NOT to be used under bandages as a comfort measure or to secure primary dressings unless patients has known sensitivity to wool.
09.02.02.01 Compound Sodium Lactate Intravenous Infusion 

Hospital use only

A5.08.07 Comprilan® 

Preferred local option

Specialist recommendation only
100 % cotton short stretch compression bandage
Type of wound product is suitable for
Venous leg ulceration
Varicosis
Management of chronic oedema
Management of primary and secondary lymphoedema
Deep venous thrombosis
Thrombophlebitis
Duration dressing remains on wound before changing
1 to 7 days
Frequency of dressing change
Dependant on exudate levels if wound present or oedema management.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.
Advanced Peripheral arterial occlusive disease
Decompensated cardiac insufficiency
Septic phlebitis
Phlegmasia coerula doleris
Rationale for inclusion in formulary
Cotton short stretch bandage. Used by lymphoedema nurse specialists

03.04.03 Conestat Alfa Ruconest®

Hospital only- NHSE Commissioned

A5.15 Conotrane cream 

Barrier cream
Type of wound product is suitable for
Intact skin, not to be applied to a wound.
To protect the skin from moisture, irritation and chafing.
Frequency of use
Application at every episode of hygiene. Apply a thin layer sparingly
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used in conjunction with containment products for incontinence due to the inclusion of liquid paraffin in the ingredients, which will repel urine/faeces back onto
the skin.
Any allergy to the listed ingredients
Rationale for inclusion in formulary
Dermatology approved

13.02.02 Conotrane® 

Over the counter preparation suitable for self-care/purchase if appropriate

06.01.06 Continuous Glucose Monitoring Dexcom One Sensor ®

In line with NHSE criteria, see annex A in the following link: https://www.blackcountryformulary.nhs.uk/docs/files/National-arrangements-for-funding-of-relevant-diabetes-patients-June-2020-Updated-final.pdf

 

09.06.07 Copper (chelated) 
07.03.05 Copper intra-uterine devices 

Various

09.04 Corn flour and corn starch 
  • Slow release CHO to prevent hypoglycaemia in GSD
  • Slow release carbohydrate to prevent hypoglycaemia in all types of GSD. Cheaper than glycosade and easier to mix. Used in less severe forms of GSD. Between 1 to 2g/kg body weight is prescribed dependent on age, weight and clinical symptoms of hypoglycaemia. Doses may be given at regular intervals during the day and night or at bedtime only. The dose and frequency of dose should always be advised by the specialist dietitian according to the needs of the patient
  • For glycogen storage disease
05.01.08 Co-trimoxazole 
05.01.08 Co-trimoxazole 
A5.08.03 Cotton Stockinette BP 

Sub bandage lining
Type of wound product is suitable for
To be used under retention and compression bandages
Duration dressing remains on wound before changing
As required
Frequency of dressing change
As required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used under Coban compression therapy
Not to be used under compression hosiery
Does not conform to a limb shape. If conformity is required, choose CliniFast
Rationale for inclusion in formulary
Cost effective choice when conformity to a limb is not required

09.04 Cow & Gate Pepti-Junior®  
  • Infant and child: Hydrolysate formula
  • Whey hydrolysate. Use in infants who have malabsorption problems and require a peptide and MCT containing feed. Eg after gut surgery
  • Use as tube or oral feed
  • Disaccharide and/or whole protein intolerance, or where amino acids and peptides are indicated in conjunction with medium chain triglycerides
08.01.05 Crisantaspase Erwinase®

Commissioned by NHSE

08.01.05 Crizanlizumab Adakveo®

In line with NICE

08.01.05 Crizotinib Xalkori®

Hospital Only

In line with NICE

13.03 Crotamiton Eurax®

Over the counter preparation suitable for self-care/purchase if appropriate

A5.03.04 Cutimed® Sorbact® 

Specialist recommendation only

DACC coated dressings providing antimicrobial properties, available in a pad, gel, gel sheet, ribbon, round swab and rectangular swab

Type of wound product is suitable for
Colonised or clinically infected moist wound, suitable for any wound type

Duration dressing remains on wound before changing
1-3 days

Frequency of dressing change
1-3 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use in combination with oils and creams
Known hypersensitivity to ingredients
Not for dry wound
Not for heavily exuding wounds

Rationale for inclusion in formulary
Alternative to available antimicrobials

A5.02.02 C-View  

Vapour-permeable adhesive film

Type of wound product is suitable for
Dry non infected wounds, retention of lines, fixation of secondary dressings, protection of intact skin, protection of skin against friction, protection of newly epithelialized wounds

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Clinically infected wounds, bleeding or exuding wounds

Rationale for inclusion in formulary
Retention of lines, protection of intact skin, fixation of other dressings. Waterproof

A5.02.02 C-View Post-Op 

Vapour-permeable adhesive film with absorbent pad

Type of wound product is suitable for
Dry non infected wounds, low exuding wounds, minor burns, protection of intact skin, protection of newly epithelialized wounds

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Clinically infected wounds, bleeding or exuding wounds

Rationale for inclusion in formulary
Protection of intact skin, low exuding wounds. Waterproof

04.06 Cyclizine 

Tablets

Injection - for use in palliative care only

04.06 Cyclizine 

For use in palliative care only

11.05 Cyclopentolate Hydrochloride 
11.05 Cyclopentolate Hydrochloride  
11.05 Cyclopentolate Hydrochloride Single Use 

Branded preservative free drops i.e. single use drops should be prescribed where available as manufactured 'specials' cost significantly more and don't have a product license.
Restricted to patients needing preservative free.

On specialist ophthalmologist recommendation

08.01.01 Cyclophosphamide 

Commissioned by NHSE
Injection-hospital only
Tablets-for oncology

05.01.09 Cycloserine 

Hospital use only under microbiological and Tuberculosis specialist advice 

06.04.02 Cyproterone acetate 

BRANDS

  • Androcur

 

 

08.03.04.02 Cyproterone Acetate 
09.04 Cystine500® 
  • To correct cysteine deficiency in homocystinuria
  • The only pre-measured sachet of cysteine to correct cysteine deficiency in homocystinuria. The dose and frequency of administration will be determined by the specialist dietitian
  • Nutritional supplement for the dietary management of inborn errors of amino acid metabolism in adults and children from birth
08.01.03 Cytarabine  Commissioned by NHSE
Hospital only
08.01.03 Cytarabine-Daunorubicin Liposomal  Vyxeus®

In line with NICE

02.08 Dabigatran 
08.01.05 Dabrafenib with trametinib 

In line with NICE

08.01.05 Dacarbazine 
08.01.05 Dacomitinib Vizimpro®

In line with NICE

08.01.02 Dactinomycin 

Commissioned by NHSE
Hospital only

05.01.07 Dalbavancin 

Hospital use only under microbiological advice 

09.04 Dalia 
  • Low protein milk for children and adults with phenylketonuria and other disorders of protein metabolism
  • Low protein milk (similar energy content to cow’s milk) for children and adults with phenylketonuria and other disorders of protein metabolism
02.08.01 Dalteparin 

Use current Place/Trust Status and local guidelines 

Sandwell

Black Non formulary

Wolverhampton

Amber Initiation

Walsall

Black Non formulary

Dudley

 Red

 

02.08 Danaparoid Orgaran®
06.07 Danazol 

Off label use for hereditary angiodema

01.06.02 Danthron 
10.02.02 Dantrolene 
15.01.08 Dantrolene Sodium Dantrium Intravenous®

Hospital only

06.01.02.03 Dapagliflozin  

 

  for treating Type 2 diabetes and chronic kidney disease in line with NICE 

Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis)

Amber Recommended Treatment of all grades of symptomatic heart failure 

 

SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

06.01.02.03 Dapagliflozin / Metformin Xigduo®
05.01.10 Dapsone 

Hospital use only under microbiological advice 

05.01.07 Daptomycin 

Hospital use only under microbiological advice 

08.01.05 Daratumumab Darzalex®

In line with NICE

09.01.03 Darbepoetin Alfa Aranesp® •NHSE commissioned for use in renal dialysis

•Primary Care commissioned for use in cancer- in line with NICE TA323

08.03.04.02 Darolutamide Nubeqa®

In line with NICE

05.03.01 Darunavir 
05.03.01 Darunavir with cobicistat Rezolsta®

Blueteq /prior approval form

05.03.01 Darunavir with cobicistat, emtricitabine and tenofovir alafenamide Symtuza®

Blueteq /prior approval form

08.01.05 Dasatinib Sprycel®

In line with NICE

08.01.02 Daunorubicin 

Commissioned by NHSE
Hospital only

A5.05.03 Debrisoft® 

Preferred local option
Debridement pad to cleanse and debride wounds.
Type of wound product is suitable for
Acute or chronic wounds with surface debris eg pressure ulcers, leg ulcers, diabetic foot ulcers
Hyperkeratosis
Duration dressing remains on wound before changing
Not applicable
Frequency of dressing change
At each dressing change or as required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to polyester
Heavy slough and necrotic tissue may require autolytic debridement to soften prior to
use
Thick hyperkeratosis may take more than one treatment
Must be wet with clean warm water prior to use
Do not get an emollient on the pad as this blocks the monofilaments
Rationale for inclusion in formulary
Lifts debris, superficial slough and exudate without damaging new granulation or
epithelial cells
Removes biofilms
Lifts hyperkeratosis and dry flaking skin peri-wound
Recommended by NICE
Treatment well tolerated
Convenient, easy to use, disposable single use pad

08.01.03 DecitabineRestricted Item  Dacogen® NHSE do not routinely commission this
Hospital only
09.01.03 Deferasirox Exjade® NHSE commissioned
09.01.03 Deferiprone Ferriprox® NHSE commissioned
08.03.04.02 Degarelix 

•Commissioned by CCGs, in line with NICE

•Transfer to Primary Care supported by an ESCA.

ESCA: Degarelix

05.01.09 Delamanid Deltyba ®

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.03 Demeclocycline 

For Antimicrobial use by Microbiologist and Hyponatraemia indications

06.05 Demeclocycline 

Treatment of hyponatraemia resulting from inappropriate secretion of antidiuretic hormone, if fluid restriction alone does not restore sodium concentration or is not tolerable

16.01 Demo Drug nelDemo

Green Area 1

Red Area 2

Black Area 2


Notes here about the product

16.01 Demo Drug nelDemo
Area 1

Green
Area 2

Red
Area 2

Black

Notes about medicines

16.01 Demo Drug nelDemo

Restricted to Black In Area 3

06.06.02 Denosumab Xgeva® For specialist use only in line with NICE TA265
06.06.02 Denosumab Prolia®

 

Dudley 

Amber Initiation

Sandwell

Amber SC

ESCA-Denosumab-Sandwell only

Walsall

Red

Wolverhampton 

Amber Recommended with RiCaD 

Wolverhampton only

13.08.02 Dermablend® 
  • Specialist recommendation
13.10.05 Dermabond ProPen® 

Hospital only

13.08.02 Dermacolor® 
  • First line
  • Specialist recommendation
  • 100 shades available
  • FP10 prescriptions should be endorsed "ACBS"
13.02.01 Dermatonics Once Heel Balm 

Specialist recommendation for epidermolysis bullosa only 

A5.13 Dermatonics Once Heel Balm 

Preferred local option

Podiatry recommendation only

Cream containing 25% urea

Type of wound product is suitable for
To moisturise dry skin on the soles of feet
For use on adults and children over 12 years of age

Frequency of use
Reapply daily

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients, contains beeswax and lanolin
Not to be used on children under 12

Rationale for inclusion in formulary
Treatment of dry skin conditions of the foot. Dermatology approved

15.02 Dermogesic spray 

Hospital only

A5.13 Dermol 500 lotion 

Emollient lotion containing an antimicrobial
Type of wound product is suitable for
For dry and pruritic skin conditions including eczema and dermatitis. Can be applied to skin as an emollient or used as a soap substitute
Frequency of use
Reapply daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients, contains benzalkonium chloride,
0.1%, chlorhexidine hydrochloride 0.1%, liquid paraffin, isopropyl myristate. Should not be used unless infection is present or is a frequent complication
Rationale for inclusion in formulary
Treatment of dry skin requiring antimicrobial properties
Dermatology approved

13.02.01.01 Dermol 600® Emollient Bath Additive 

Over the counter preparation suitable for self-care/purchase if appropriate

13.02.01 Dermol® 500 

For short term use only

Over the counter preparation suitable for self-care/purchase if appropriate

09.01.03 Desferrioxamine Mesilate  NHSE commissioned
15.01.02 Desflurane Suprane®

HOSPITAL ONLY

06.05 Desmopressin Desmotabs®

Primary Nocturnal enureis -Paediatrics

06.05 Desmopressin 

Amber Recommended Paediatric Nocturnal enuresis

Amber Initiation Diabetes Insipidus

06.05 Desmopressin 

Diabetes Insipidus

06.05 Desmopressin 
07.03.02.01 Desogestrel 75mcg 

Prescribe generically

09.04.01 Desserts 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Important protein-free foods to provide important energy, assist dietary adherence and provide variety when natural protein tolerance is very limited. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein
04.06 Dexamethasone 

For use in palliative care only

04.06 Dexamethasone 

For resistant nausea and vomiting only

£££££

06.03.02 Dexamethasone 

 

 

11.04.01 Dexamethasone Maxidex®

For use on the advice of a specialist

11.04.01 Dexamethasone 700mcg  Ozurdex®

For macular oedema secondary to retinal vein occlusion - use in line with NICE TA229

For diabetic macular oedema - use in line with NICE TA349

11.04.01 Dexamethasone eye drops 

Branded preservative free drops i.e. single use drops should be prescribed where available as manufactured 'specials' cost significantly more and don't have a product license

Restricted to patients needing preservative free

For use on the advice of a specialist

For post corneal transplants or OSD

Use the agent  with the lowest acquisition cost

06.03.02 DEXAMETHASONE PHOSPHATE INJECTION 
12.01.01 Dexamethasone with Antibacterial Sofradex®
12.01.01 Dexamethasone with neomycin and glacial acetic acid Otomize®
11.04.01 Dexamethasone with Neomycin and Polymyxin B sulphate Maxitrol®

Steroid- antibiotic combination eye drops are only recommended for use under close specialist supervision and after ocular surgery.

On specialist ophthalmologist recommendation

11.04.01 Dexamethasone with tobramycin Tobradex®
04.04 Dexamfetamine 

Please note that commissioning discussion is underway. However the present status is as follows:-

Amber SC  Age 6 and over - Solihull practices.  Supported with ESCA

Amber SC  Age 16 and over - Birmingham practices.  Supported with ESCA

Red Age under 16 - Birmingham practices

Amber SC  Supported with an ESCA - Sandwell & West Birmingham CCG for patients seen by the Black Country ADHD Services

08.01 Dexrazoxane Savene®
09.04 Dialamine® 
  • Protein and carbohydrate
  • This is a source of essential amino acids for use in low protein diets with urea cycle disorders. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Hypoproteinaemia, chronic renal failure, wound fistula leakage with excessive protein loss, conditions requiring a controlled nitrogen intake, and haemodialysis
  • Not suitable for child under 6 months
04.07.02 Diamorphine salts 
04.01.02 Diazepam 
04.01.02 Diazepam 
04.01.02 Diazepam 

Inpatient use and prison settings only

04.08.02 Diazepam Rectal tubes
04.10 Diazepam 
04.10.01 Diazepam 
10.02.02 Diazepam 
15.01.04.01 Diazepam 

Hospital only

04.01.01 Diazepam liquid 

Inpatient use and prison settings only

10.01.01 Diclofenac 

Enteric coated tablets (most cost effective choice)
 
Not first line NSAID treatment choice

Renal colic and other acute severe painful conditions

Assess CVD risk

 
For short term use only
 - no information on their use for longer than 3 months.

Dispersible tablets reserved for paediatric use and those patients with swallowing difficulties or specific clinical need

10.01.01 Diclofenac 

£££££

Short term use only

Assess CVD risk

Not first line NSAID

For patients with swallowing difficulties

Renal colic and severe acute painful conditions

11.08.02 Diclofenac  Voltarol® Ophtha SDU

For use on advice of specialist

15.01.04.02 Diclofenac 

Post operative use only then switch to oral ibuprofen or naproxen.

13.08.01 Diclofenac 3% gel Solaraze®

Apply thinly twice a day. Max 8g daily
Treat for 60-90 days ( effect may not be seen until 30 days after stopping use).

For specialist initiation

11.08.02 Diclofenac Sodium Voltarol® Ophtha multidose

For use on advice of specialist

Restricted to patients who need preservative free

05.05 Diethylcarbamazine  
08.03.01 Diethylstilbestrol 

For oncological treatment by an experienced specialist

13.04 Diflucortolone valerate 0.3% oily cream 

Potency - Very potent

02.01 Digoxin 

Use only if still symptomatic despite optimal treatment of HF with atrial fibrillation

Take special care in elderly who may be more susceptible to digitalis toxicity

02.01 Digoxin 
02.01 Digoxin  

Use only if still symptomatic despite optimal treatment of HF with atrial fibrillation

Take special care in elderly who may be more susceptible to digitalis toxicity

02.01.01 Digoxin specific antibody fragments 
04.07.02 Dihydrocodeine 

Tablets

Oral solution for patients with swallowing difficulties

05.04 Diloxanide 
02.06.02 Diltiazem  
01.07.04 Diltiazem Cream 2% Anoheal

£££££

Unlicensed - for use only in patients intolerant of or unresponsive to GTN ointment

Store in the fridge

One tube will last a month if used as 2cm apllication TWICE DAILY

Topical diltiazem 2% may be used twice daily [unlicensed indication] in patients with chronic anal fissures unresponsive or intolerant to topical nitrates and before considering surgery

08.02.04 Dimethyl fumarate Tecfidera®

For use in relapsing - remitting Multiple Sclerosis

In line with NICE

13.05.03 Dimethyl fumarate Skilarence®

For use in moderate to severe plaque psoriasis- CCG commissioned

In line with NICE

07.04.04 DIMETHYL SULPHOXIDE Bladder Instillation 50% 

Hospital only

13.10.04 Dimeticone Hedrin®

Over the counter preparation suitable for self-care/purchase if appropriate

02.14 Dinoprostone Prostin E2®
07.01.01 Dinoprostone Prostin E2® Propess ® For Specialist/ Hospital Use Only
07.01.01.01 Dinoprostone 
08.02.03 Dinutuximab Qarziba®

In line with NICE

13.14.07 Diphenylcyclopropenone in acetone 0.00001-6.0% w/v 
02.09 Dipyridamole 

With specialist initiation

02.09 Dipyridamole MR Persantin Retard®

With specialist initiation

21 Disodium pamidronate 
  •  For Acute Trusts and Hospices.
  •  Specialist recommendation.
01.01 Disodium pamidronate 
06.06 Disodium Pamidronate 
04.10.01 Disulfiram Antabuse®
13.05.02 Dithranol Dithrocream®

All strengths-specialist recommendation only.

0.1% - 0.5% cream suitable for overnight treatment, 1% - 2% cream for maximum 1 hour

Stains everything including skin, linen, bathroom furniture and may cause skin irritation.

13.14.05 Dithranol in Lassar’s paste 0.1% w/w 
13.14.05 Dithranol in Lassar’s paste 0.5% w/w 
13.14.05 Dithranol in Lassar’s paste 1% w/w 
13.14.05 Dithranol in Lassar’s paste 10% w/w 
13.14.05 Dithranol in Lassar’s paste 15% w/w 
13.14.05 Dithranol in Lassar’s paste 2% w/w 
13.14.05 Dithranol in Lassar’s paste 4% w/w 
13.14.05 Dithranol in Lassar’s paste 8% w/w 
13.14.05 Dithranol pomade 0.4% w/w 

Dithranol 0.4% w/w, salicylic acid 2% w/w, emulsifying wax BP 25% & liquid paraffin to 100%

02.07 Dobutamine 
08.01.05 Docetaxel Taxotere®

In line with NICE

Hospital only

09.04 DocOmega® 
  • DHA supplement for low chain fatty acid and low protein diets
  • The only ACBS prescribed DHA supplement for low protein diets. The dose and frequency of administration will be determined by the specialist dietitian
  • Nutritional supplement for the dietary management of inborn errors of metabolism for adults and children from birth
01.06.02 Docusate Sodium 

Capsules 100mg, Liquid 50mg/5ml

Solution is utterly unpalatable- only fit for use down tubes

Probably acts as a softening laxative as well as a stimulant

Time to effect is approximately 24 to 48 hours

05.03.01 Dolutegravir Tivicay ®
05.03.01 Dolutegravir with rilpivirine Juluca®
01.02 Domperidone 

The MHRA has issued new advice for domperidone which states that it is no longer licensed for the relief of nausea and vomiting in children under the age of 12 years or those weighing less than 35kg (16th December 2019).

See MHRA Dug Safety Update

Domperidone is no longer recommended for managing heartburn,bloating and stomach discomfort

It should only be used for relief of nausea and vomiting at low doses for short periods (generally upto 1 week)

MHRA advice on domperidone

04.06 Domperidone 

Tablets - short term use only

Suppositories

SF suspension £££££ - for patients with swallowing difficulties only

04.11 Donepezil 
  • Tablets
  • Orodispersible 10mg tablets sugar free (pack of 28)
02.07 Dopamine 
05.03.01 Doravirine Pifeltro®
03.07 Dornase Alfa Pulmozyme®

Commissioned by NHSE for Cystic Fibrosis only

11.06 Dorzolamide 2% 

On Specilaist Ophthalmologist Recommendation

11.06 Dorzolamide 2% with Timolol 0.5% SDU Eye Drops  Cosopt®

On Specilaist Ophthalmologist Recommendation

11.06 Dorzolomide 2%  Trusopt®

On Specialist Ophthalmologist Recommendation

11.06 Dorzolomide 2% with Timolol 0.5% 

On Specialist Ophthalmologist Recommendation

08.01.05 Dostarlimab Jemperli®

In line with NICE

13.02.01 Doublebase  

Over the counter preparation suitable for self-care/purchase if appropriate

03.05.01 Doxapram Dopram®
03.05.01 Doxapram 
15.01.07 Doxapram Dopram®

Hospital only

02.05.04 Doxazosin 
07.04.01 Doxazosin 

Reduce BP - care with other antihypertensives
Caution in elderly
Care with hepatic and severe renal impairment
Contraindicated in postural hypotension or micturition syncope

Black MODIFIED RELEASE TABLETS ARE NON-FORMULARY

13.03 Doxepin hydrochloride Xepin®

Supported by a RICaD 

08.01.02 Doxorubicin Hydrochloride 

Commissioned by NHSE
Hospital only

08.01.02 Doxorubicin Hydrochloride Myocet®

Commissioned by NHSE
Hospital only

05.01.03 Doxycycline 
05.04 Doxycycline 
05.04 Doxycycline Vibramycin-D®
13.06.02 Doxycycline 

•Topical treatments should be used first line.

•Oral antibiotics should be reserved for acne, if topical treatment is not adequately effective or if it is inappropriate


Take with or after food and avoid sunlight


Please refer to Primary Care Antimicrobial Guidelines

02.03.02 Dronedarone 

In line with NICE TAG TA197

Use current status at Place/Trust

Sandwell

Red

Wolverhampton

Amber SC

ESCA Dronedarone-Wolverhampton only

Walsall

Amber SC

Dudley

Amber Initiation

ESCA Dronedarone-Dudley only

 

03.01.05 Drug Delivery Device 
  • Aerochamber Plus
  • Aerochamber Plus Flow-vu Anti-static
  • Aerochamber Plus Flow-vu Anti-static With Adult Large Mask
  • Aerochamber Plus Flow-vu Anti-static With Adult Small Mask
  • Aerochamber Plus Flow-vu Anti-static With Medium Mask Child 1-5 Years
  • Aerochamber Plus Flow-vu Anti-static With Small Mask Infant 0-18 Months
  • Aerochamber Plus Flow-vu Anti-static Youth 5
  • Aerochamber Plus With Adult Mask
  • Aerochamber Plus With Child Mask
  • Aerochamber Plus With Infant Mask
  • Volumatic
  • Volumatic With Paediatric Mask
  • Zerostat Vt Spacer
14.04 DTaP/IPV/Hib/HepB Infanrix-hexa®, Vaxelis®
06.01.02.03 Dulaglutide Trulicity®

PLEASE PRESCRIBE BY BRAND NICE Guidance on prescribing

 

04.03.04 Duloxetine Cymbalta®
04.07.03 Duloxetine Cymbalta®

Third line after gabapentin

Dot On advice of specilaist - initiate at 30 mg OD for 1 month, then 60 mg OD

Dot More cost effective options available

Dot NICE suggests 1st line for Diabetic neuropathy

Dot Low abuse potential , high cost £££££

Dot Not licensed for use in children

06.01.02.03 Duloxetine 

Prescribe generically as 30mg & 60mg.

90 and 120mg not cost-effective

07.04.02 Duloxetine 
09.04 Duocal® Super Soluble 
  • Fat and Carbohydrate
  • For renal children with fluid restriction
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat (or fat and carbohydrate) supplement
19.12 DuoDERM® Extra Thin  Light Exudate Only
Indications: necrotic, sloughy, granulating and epithelialising wounds. Primary dressing which provides moist environment for autolysis. Waterproof and requires 1.5-2cm margin around wound to ensure adhesion and to reduce leakage. Warm with hands to make more pliable and adhesive. To remove press down on skin and carefully lift corners stretching the edges until free. Not suitable for infected wounds as they are occlusive (unless aerobic infection isolated). Not suitable for heavily exuding wounds as they have limited absorption capacity.
Contains porcine extract
Without porcine extract: Hydrocolloid dressings are available without porcine extract.
Please contact Tissue Viability Service for advice if required.
19.12 DuoDERM® Signal  Light to moderate exudate
Indications: necrotic, sloughy, granulating and epithelialising wounds. Primary dressing which provides moist environment for autolysis. Waterproof and requires 1.5-2cm margin around wound to ensure adhesion and to reduce leakage. Warm with hands to make more pliable and adhesive. To remove press down on skin and carefully lift corners stretching the edges until free. Not suitable for infected wounds as they are occlusive (unless aerobic infection isolated). Not suitable for heavily exuding wounds as they have limited absorption capacity.
Contains porcine extract
Without porcine extract: Hydrocolloid dressings are available without porcine extract.
Please contact Tissue Viability Service for advice if required.
A5.02.04 DuoDERM® 

Preferred local option

The adhesive layer forms a cohesive gel when in contact with wound exudate
Available as Extra thin or Signal (Bordered)

Type of wound product is suitable for
Dry to lightly exuding wounds
Non infected
Acute or Chronic wounds

Duration dressing remains on wound before changing
Up to 7 days maximum

Frequency of dressing change
3-7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not suitable for infected wounds, full thickness burns or wounds with exposed bone, muscle or tendon or wounds that are likely to macerate, particularly on plantar surface of foot
Not for diabetic foot ulcers
Not for ischaemic wounds
Known product or component sensitivity

Rationale for inclusion in formulary
Conformable, waterproof, aids autolysis. Protect surrounding skin , reduced risk of
blistering. Cost effective

03.04.03 Dupilumab Dupixent®
08.01.05 Dupilumab Dupixent®
08.01.05 Durvalumab Imfinzi®

In line with NICE

06.04.02 Dutasteride Avodart®
09.04 EAA Supplement 
  • Consists of essential amino acids for the treatment of urea cycle disorders
  • Essential amino acid supplement for use in urea cycle disorders and the cerebral creatine deficiency syndrome: guanidinoacetate methyltransferase (GAMT) deficiency. The only pre-measured sachet of essential amino acids with added vitamins and minerals for the treatment of urea cycle disorders. This is particularly important as most of our families with UCD do not speak English as their first language so require pre-measured products. Unmeasured use of essential amino acid supplements in UCD could lead to hyperammonaemia, acute brain encephalopathy and ITU admission. The dose and frequency of administration will be determined by the specialist dietitian
  • Nutritional supplement for the dietary management of disorders of protein metabolism including urea cycle disorders in children over 3 years
A5.11 Easy-Slide  

Preferred local option

Application aid for open toe compression garments

A5.01.02 Eclypse® 

Approved June 2018 to replace Flivasorb®

07.02.02 Econazole Gyno-Pevaryl®
11.03.02 Econazole 1% eye drops 
02.08 Edoxaban  

 



15.01.06 Edrophonium 

Hospital only

10.02.01 Edrophonium Chloride 

Hospital use only

05.03.01 Efavirenz with emtricitabine and tenofovir disoproxil 
05.03.01 Elbasvir with grazoprevir Zepatier®
09.04.02 Elemental 028® Extra 
  • Less than 1 kcal/mL and less than 5g protein/100 mL
  • Amino acid formula (essential and non-essential amino acids)
  • Pts with IBD, multiple allergy
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula
09.04.02 Elemental 028® Extra 
  • Less than 1 kcal/mL and less than 5 g protein/100 mL
  • Amino acid formula (essential and non-essential amino acids)
  • Pts with IBD, multiple allergies. For tube feed and oral feeding. Alter concentration of feed to support individual patient’s nutritional needs.
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula
09.08.01 Eliglustat Cerdelga®

In line with NICE Highly Specialised Technology guidance- NHSE commissioned

06.04.01.01 Elleste Solo 
06.04.01.01 Elleste-Duet Conti®  
09.01.04 Eltrombopag Revolade® In line with NICE TA293.
05.03.01 Elvitegravir with cobicistat, emtricitabine and tenofovir alafenamide Genvoya®
06.01.02.03 Empagliflozin 

 Green For treating type 2 diabetes
Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis)

Amber Recommended treatment of all grades of symptomatic heart failure

SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

06.01.02.03 Empagliflozin / Metformin  Synjardy ®
06.01.02.03 Empagliflozin/Linagliptin 

 

 

 

05.03.01 Emtricitabine Emtriva®
05.03.01 Emtricitabine 200mg, Rilpivirine 25mg and Tenofovir 245mg Eviplera®

Blueteq /prior approval form 

05.03.01 Emtricitabine with rilpivirine and tenofovir alafenamide  Odefsey®
05.03.01 Emtricitabine with tenofovir alafenamide Descovy®
05.03.01 Emtricitabine with tenofovir disoproxil 
A5.14 Emulsifying ointment 

Preferred local option

Emollient ointment containing emulsifying wax, white soft paraffin and liquid paraffin
Type of wound product is suitable for
For treatment of dry skin conditions
Frequency of use
Daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Treatment of dry skin
Dermatology approved

13.02.01 Emulsifying Ointment BP 

Most greasy option

Over the counter preparation suitable for self-care/purchase if appropriate

Use frequently and liberally. prescribe in adequate quantities
In generalised eczema, an adult will require 500g per week and a child will require 250g a week

08.01.05 Encorafenib plus cetuximab Braftovi® + Erbitux®

In line with NICE

08.01.05 Encorafenib with binimetinib Braftovi® + Mektovi ®

In line with NICE

Providers are NHS hospital trusts

09.04 Energivit® 
  • Fat and Carbohydrate
  • Infant feed - Metabolic disorder pts
  • Also protein-free (containing fat, carbohydrate, vitamins and minerals) powder necessary for infants with inborn errors of protein metabolism. It is the only protein-free infant feed for patients with urea cycle disorders and organic acidaemias. It is commonly used in combination with a measured amount of natural protein e.g. expressed breast milk. It will help meet essential energy and nutrient requirements. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • For children requiring additional energy, vitamins, minerals, and trace elements following a protein-restricted diet
05.03.01 Enfuvirtide Fuzeon®
02.08.01 Enoxaparin 

Use current Place/Trust Status and local guidelines 

 Sandwell

Green Single use in suspected DVT

Green Pregnant women - see URGENT PRESCRIBING OF ENOXAPARIN IN PROPHYLYAXIS OF VENOUS THROMBOEMBOLISM (VTE) IN PREGNANCY

Red For all other indications

The APC's view is that on clinical grounds, the status for certain indications approved by APC should be Amber Shared Care, supported by an ESCA. These indications are:

  • Deep vein thrombosis (including paediatrics)
  • Pulmonary embolism (including paediatrics)
  • Intolerance/unsuitable for oral anticoagulants
  • Certain cancer patients
  • Injectable drug users
    HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED (ESCAs to be developed). This should not prevent individuals in primary care providing initial prescriptions in urgent situations e.g. pregnancy where there is a high thrombotic risk (see guidance linked below).

Wolverhampton

Amber Initiation 

Walsall

Green Preferred brand-Inhixa and Clexane 

Dudley

Red

02.01.02 Enoximone  
09.04 Enshake® 
  • Protein, fat, and carbohydrate
  • First choice for patients with very high energy requirement eg. cystic fibrosis
  • In adults with cystic fibrosis, nutritional advice and interventions should be aimed at maintaining a BMI of 22kg/m2 in women and 23kg/m2 in men, as these are associated with better lung function (Nutritional management of CF – Consensus document – 2016)
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat or carbohydrate (with protein) supplement. Not suitable for child under 1 year; use with caution in child 1–6 years
09.04.02 Ensure® Twocal 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High calorie vegetarian fish oil free
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula ; also haemodialysis and CAPD
04.09.01 Entacapone 
05.03.03 Entecavir Baraclude®
05.03.03 Entecavir 
15.01.02 Entonox® 

HOSPITAL ONLY

08.01.05 Entrectinib  Rozlytrek®

In line with NICE

08.03.04.02 Enzalutamide Xtandi®

Commissioned by NHS England

Hospital only

In line with NICE and available from day 91 following publication of TA

13.14.07 Eosin solution 2% w/v 
13.02.01 Epaderm 

Over the counter preparation suitable for self-care/purchase if appropriate

A5.14 Epaderm ointment 

Emollient ointment containing liquid paraffin, yellow soft paraffin and emulsifying wax
Type of wound product is suitable for
For use on all dry skin conditions and with dry or wet wrapping techniques
Frequency of use
Daily or more frequently if required
Caution/contraindications
Non listed
Rationale for inclusion in formulary
Treatment of dry skin conditions.
Dermatology approved

02.07 Ephedrine 
12.02.02 Ephedrine 0.5% 

Short Term Use Only

Do not exceed 7 days use. Rebound congestion may occur on withdrawal

Maximum of 5 days in children aged 6-12 years. Do not use in children under 6 years.

03.01.01.02 Ephedrine Hydrochloride 
13.02.01 Epimax 
08.01.02 Epirubicin hydrochloride 

Commissioned by NHSE
Hospital only

02.02.03 Eplerenone  
09.01.03 Epoetin beta NeoRecormon® •NHSE commissioned for use in renal dialysis

•Primary Care commissioned for use in cancer- in line with NICE TA323

02.08 Epoprostenol Flolan®
02.06 Eptifibatide 
04.07.04.02 Erenumab Aimovig®

In line with NICE

09.06.04 Ergocalciferol  

Dot 20,000 units solution
Dot capsules (Osto D2)
Dot injection-hospital only 

07.01.01 Ergometrine Maleate  For Specialist/ Hospital Use Only
07.01.01 Ergometrine Maleate and Oxytocin Syntometrine® For Specialist/ Hospital Use Only
08.01.05 Eribulin Halaven®

In line with NICE

Hopsital ONLY - NHSE Commissioned

08.01.05 Erlotinib Tarceva®

In line with NICE and available from day 91 following pubication of TA

05.01.02.02 Ertapenem 

 Amber Rec under OPAT Scheme in Primary care

 Hospital use under microbiological advice 

06.01.02.03 Ertugliflozin 

In line with NICE


Do not use SGLT2-inhibitors in patients with T1DM,
regardless of CKD and/or heart failure status due to risk
of DKA (diabetic ketoacidosis)

 

05.01.05 Erythromycin 
05.01.05 Erythromycin ethyl succinate 
05.01.05 Erythromycin lactobionate 
04.08.01 Eslicarbazepine 

Should only be considered following referral to a tertiary care specialists  and after oxcarbazepine has been tried

Supported by an ESCA

02.04 Esmolol 

Hospital use only

01.03.05 Esomeprazole 
01.03.05 Esomeprazole injection 
06.04.01.01 Estraderm MX®  
06.04 Estradiol 10mg Vagifem®, Vagirux®

Pessary 

  • Vagifem
  • Vagirux
06.04 Estradiol 1mg /2mg  
06.04 Estradiol hemihydrate lenzetto 153 mg/spray ®

 

 

07.03.01 Estradiol/dienogest Qlaira®

•Phasic (28-day ‘Every day’ preparation)
•Only for Synphase® failure

06.04 Estradiol/dydrogesterone 
06.04 Estradiol/Medroxyprogesterone 
06.04 Estradiol/Norethisterone 

 

2nd line to patches 

https://pcwhf.co.uk/wp-content/uploads/2021/02/Prescribing-HRT-3.pdf 

06.04.01.01 Estradot®  
08.01.01 Estramustine phosphate Estracyt®

Commissioned by NHSE

06.04 ESTRIOL 0.01% Cream 
06.04.01.01 Estriol® 0.01% 
02.11 Etamsylate Dicynene®
10.01.03 Etanercept Enbrel®

Hospital use only

Use in children is commissioned by NHSE specialised commissioning not SWB CCG

13.05.03 Etanercept 

In line with NICE

09.05.01.02 Etelcalcetide Parsabiv®

Commissioned by NHS England

In line with NICE

05.01.09 Ethambutol  

Hospital use only under microbiological and Tuberculosis specialist advice 

Ethambutol liquid 400mg in 5ml (unlicensed)

06.04.01.01 Ethinylestradiol 
07.03.01 Ethinylestradiol / levonorgestrel phased pill TriRegol®

Phasic Standard Strength (21 Day preparation)

Phased peparations are generally reserved for women who either do no have withdrawal bleeding or who have breakthrough bleeding with monophasic products.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

07.03.01 Ethinylestradiol 20 mcg / norethisterone 1mg Loestrin 20®

Monophasic LOW strength (21 Day preparation)

For pubertal induction in adolescent patients or premature ovarian failure ONLY.

07.03.01 Ethinylestradiol 20mcg / desogestrel 150mcg Gedarel®20/150, Lestramyl®20/150

Lestramyl is the preferred brand however if there are supply issues use Gedarel.

Monophasic LOW strength (21 Day preparation)

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

07.03.01 Ethinylestradiol 20mcg / gestodene 75 mcg Millinette®20/75

Monophasic LOW strength (21 Day preparation)

07.03.01 Ethinylestradiol 30 mcg / drospirenone 3 mg 

•Monophasic standard strength (21-day preparation)

APC approved brands:
Yacella®
Acondro®
Dretine®

07.03.01 Ethinylestradiol 30mcg / desogestrel 150mcg Gedarel®30/150, Lestramyl®30/150

Lestramyl preferred brand however if supply issues use Gedarel.

Monophasic standard strength (21 Day preparation)

Use standard monophasic for most women. Use phased preparations for those who do not have withdrawal bleeding or experience breakthrough bleeding with monophasic.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

07.03.01 Ethinylestradiol 30mcg / gestodene 75 mcg Millinette®30/75


 Monophasic standard strength (21 Day preparation)

07.03.01 Ethinylestradiol 30mcg / levonorgestrel 150mcg Microgynon 30 ED®

Monophasic standard strengh (28-day "Everyday" preparation)

07.03.01 Ethinylestradiol 30mcg / levonorgestrel 150mcg Rigevidon®, Levest®

Monophasic standard strength (21 Day preparation)

Rigevidon® 

Levest®

Use standard monophasic for most women. Use phased preparations for those who do not have withdrawal bleeding or experience breakthrough bleeding with monophasic.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

07.03.01 Ethinylestradiol 35 mcg / noresthisterone 500mcg Brevinor®

Monophasic Standard Strength (21 Day preparation)

Use standard monophasic for most women. Use phased preparations for those who do not have withdrawal bleeding or experience breakthrough bleeding with monophasic.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

07.03.01 Ethinylestradiol 35 mcg / norgestimate 250 mcg Lizinna®

Monophasic Standard Strength (21 Day preparation)

Use standard monophasic for most women. Use phased preparations for those who do not have withdrawal bleeding or experience breakthrough bleeding with monophasic.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

Carry small increased risk of venous thromboembolism, higher with desogestrel and gestodene than other progestogens.

Use low strength if risk factors for circulatory disease and COC is otherwise suitable.

07.03.01 Ethinylestradiol/cyproterone acetate Dianette®
07.03.01 Ethinylestradiol/norelgestromin Evra®

For patients with poor compliance or absorption problems

Restricted to women likely to comply poorly with combined oral contraceptives and those with metabolic problems.

The risk of venous thromboembolism with transdermal patches may be slightly increased compared with combined oral contraceptives that contain levonorgestrel.

Note BNF contraindications and cautions in migraine. Advise all women to report increase in headache frequency and stop if focal symptoms not typical of aura > 1 hour.

07.03.01 Ethinylestradiol/norethisterone Synphase®

•Phasic 21-day preparation
•Added to formulary May 2017 as alternative to Trinovum which was discontinued in 2016

04.08.01 Ethosuximide 

On specialist advice

MHRA Advice
When prescribing for epilepsy, the potential for clinically relevant differences to exist between different manufacturers' product is considered to be extremely low. However, consider otherpatient / carer related factors, such as negative perceptions about alternative products and/or other issues related to the patient such co-morbid autism, mental health issues, or learning disability

15.02 Ethyl Chloride Cryogesic® Spray

Hospital only

06.06.02 Etidronate disodium 

In line with NICE

15.01.01 Etomidate Etomidate-Lipuro®

HOSPITAL ONLY

15.01.01 Etomidate Hypnomidate®

HOSPITAL ONLY

07.03.02.02 Etonogestrel Nexplanon®
08.01.04 Etoposide  Commissioned by NHSE
Hospital only
15.01.04.02 Etoralac 

Hospital only

05.03.01 Etravirine Intelence®
13.02.01 Eucerin® 10% urea Intensive  

Over the counter preparation suitable for self-care/purchase if appropriate

08.01.05 Everolimus Votubia®
08.01.05 Everolimus Afinitor®

In line with NICE

Hospital only

08.02.02 Everolimus Certican®

In line with NICE

02.12 EvolocumabRestricted Item  Repatha® In line with NICE.
06.04.01.01 Evorel Conti® 
06.04 EVOREL SEQUI PATCH 
06.04.01.01 Evorel®  
08.03.04.01 Exemestane 
06.01.02.03 Exenatide 
  •  prolonged-release suspension for injection
02.12 Ezetimibe Ezetrol®

In line with NICE.

02.11 Factor VIIa (Recombinant) Eptacog alfa (activated)
05.03.02.01 Famciclovir 

Second line for Shingles 

10.01.04 Febuxostat Adenuric®

Second line choice as per APC minutes (June 2019)

For use in line with NICE guidance for patients intolerant of allopurinol (due to adverse effects sufficient to warrant discontinuation, or to prevent full dose escalation for optimal effectiveness) or for whom allopurinol is contraindicated.

08.01.05 Fedratinib Inrebic®

In line with NICE

02.06.02 Felodipine 
06.04 Femoston Conti ® 
06.04 Femoston Sequential ® 
06.04.01.01 Femseven ® 
06.04.01.01 Femseven Conti® 
06.04.01.01 Femseven Sequi® 

 

 2nd line to Evorel Sequi®

02.12 Fenofibrate 
04.07.02 Fentanyl  Palliative care use only
04.07.02 Fentanyl 
04.07.02 Fentanyl  Palliative care use only
04.07.02 Fentanyl  

For patients with swallowing difficulties on stable doses of opiates or on pain team specialist advice when morphine is not suitable.
Prescribe by brand.
Follow Optimise Rx advice for most cost effective brand

15.01.04.03 Fentanyl 

Hospital only

21 Fentanyl  
09.01.01.02 Ferric Carboxymaltose Ferinject®

Hospital only

09.01.01.01 Ferric maltol  Feraccru®
  • Approved on formulary December 2017
  • For the treatment of iron deficiency anaemia (IDA) in patients with inflammatory bowel disease (IBD), unable to tolerate other oral iron formulations
  • Supported by a RICaD



09.01.01.01 Ferrous Fumarate 
09.01.01.01 Ferrous Fumarate Fersamal®
09.01.01.01 Ferrous Gluconate 

For patients intolerant to ferrous sulphate.

09.01.01.01 Ferrous Sulphate 
03.04.01 Fexofenadine 
03.04.01 Fexofenadine Telfast®
05.01.07 Fidaxomicin 

On Microbiological advice only

10.01.03 Filgotinib Jyseleca®

In line with NICE

09.01.06 Filgrastim 

Hospital only

06.04.02 Finasteride 
13.09 Finasteride 1mg Propecia ®

For hyperandrogenism in women (unlicensed)

Black listed in NHS primary care

Link to Section 13.9

08.02.04 Fingolimod 

In line with NICE

A5.03.04 Flaminal® Forte Gel 

Alginate gel. Moderate to heavily exuding wounds. Contains antimicrobial enzymes.

Type of wound product is suitable for
Colonised wound bed. More suited to sloughy wounds. Can be used on all wound types
Useful for cavity wounds and sinus’s
Requires a secondary dressing

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
1-7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Sensitivity to alginate dressings or polyethylene glycol
Full thickness burns

Rationale for inclusion in formulary
1st line antimicrobial in paediatrics
Consider as first line product if signs of colonisation or clinical infection
Does not cause cellular damage

A5.03.04 Flaminal® Hydro Gel  

Alginate gel. Low to moderate exuding wounds. Contains antimicrobial enzymes

Type of wound product is suitable for
Colonised wound bed. More suited to sloughy wounds. Can be used on all wound types
Useful for cavity wounds and sinus’s
Requires a secondary dressing

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
1-7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Sensitivity to alginate dressings or polyethylene glycol
Full thickness burns

Rationale for inclusion in formulary
1st line antimicrobial in paediatrics
Consider as first line product if signs of colonisation or clinical infection
Does not cause cellular damage

07.03.04 Flat spring diaphragm  

Sizes 55-95mm (rising in 5mm)

09.04 FlavourPac 

Flavouring preparations

  • For flavouring unpalatable flavouring amino acid supplements or feeds in inborn errors of metabolism
  • Essential for flavouring different unflavoured amino acid supplements in inborn errors of metabolism particularly for non PKU conditions. They offer common children’s favourite flavours: e.g. orange or raspberry. Flavourings are important, as amino acid formulations are unpalatable and unacceptable particularly for patients with late diagnosed conditions.
  • They cannot be purchased from a supermarket
  • For use with Vitaflo's range of unflavoured protein substitutes for metabolic diseases; not suitable for child under 3 years
02.03.02 Flecainide 
02.03.02 Flecainide 

Use current status at Place/Trust

Sandwell

Amber Recommended Initiation under specialist supervision

Contraindicated in heart failure or abnormal left ventricular function

Rhythm control should be used when:
symptomatic; under 65's; first time -lone AF; secondary to treated or corrected precipitant with congestive heart failure. Beta-blockers are first line, flecainide is a second line option when there is no structural heart disease:

Wolverhampton

Green

Walsall

Amber Initiation

Dudley

Green

01.06.05 Fleet Phospho-soda® 

For use in hospital prior to bowel procedures

19.06 Flivasorb  Superabsorbent dressing
Alternative to KerraMax Care® if patient discharged from hospital with.
Type of wound product is suitable for
For heavily exuding wounds
Can be used under compression bandages
Secondary Dressing Only
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
When exudate levels determine
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to any components of the dressing
Lightly exuding wounds
Must not be cut or torn
Rationale for inclusion in formulary
Management of heavily exuding wounds. Cost effective.
Must be applied white side to the wound bed.
09.04.01 Flour mixes and egg substitutes 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Essential protein-free basic products. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein. 1 ordinary egg = 6g protein. 100g flour = 10g protein
13.04 Flucinolone Acetonide 0.0025% Synalar 1 in 10 Dilution®

Potency: mild
Paediatric use only

13.04 Flucinolone Acetonide 0.025% Synalar® Gel

Potency - potent
Dot Gel only

05.01.01.02 Flucloxacillin 
05.01.01.02 Flucloxacillin 
05.02.01 Fluconazole 
05.02.01 Fluconazole 

Capsules 

Suspension - Only for patients with swallowing difficulties 

07.02.02 Fluconazole 

For other oral treatments please see primary care antimicrobial guidelines in chapter 5

05.02 Flucytosine 
05.02.05 Flucytosine Ancotil®
08.01.03 Fludarabine Phosphate 

Commissioned by NHSE
Injection-hospital only

06.03.01 Fludrocortisone Acetate 
13.04 Fludroxycortide tape Previously known as Haelan®

Potency - moderate

A5.16 Fludroxycortide tape 

Specialist recommendation only
Adhesive, waterproof, occlusive tape impregnated with 4mg/cm2 fludroxycortide (topical steroid)
Type of wound product is suitable for
Chronic over granulation, non acute or weeping.
Duration dressing remains on wound before changing
Cut the tape to size. Apply for 12 hours at a time, remove and discard. Apply to clean, dry skin that is shorn of any hair.
Frequency of dressing change
Apply daily for 12 hours at a time. Maximum treatment time 7 days.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Chicken pox
Tuberculosis of the skin
Hypersensitivity to any components in the tape (steroid fludroxycortide)
Facial rosacea
Acne vulgaris
Perioral dermatitis
Perianal and genital pruritis
Dermatoses in infants Dermatitis napkin eruption Bacterial, viral and fungal infections
Keep away from the eyes
Avoid prolonged use on the face
Not for untreated bacterial, fungal or viral skin lesions
Rationale for inclusion in formulary
Treatment of over granulation

15.01.07 Flumazenil Anexate®

Hospital only

12.01.01 Flumetasone with Clioquinol Locorten-Vioform®
04.07.04.02 Flunarizine 

Unlicensed medicine

Specialist use only

13.04 fluocinolone acetonide 0.025% with clioquinol 3% Synalar C®

Potency - Potent

REPLACES BETNOVATE C
Dot Cream
Dot Ointment

Restricted to use in inflammatory conditions associated with an infection with confirmed susceptibility to the antimicrobial component.

Use for short periods - typically no more than one week

11.04.01 Fluocinolone intravitreal implant Iluvien®

For specialist use only in line with NICE 

11.04.01 Fluorometholone FML®

Recommended second line for patients who have experienced a rise in intraocular pressure with other corticosteroids

On specialist ophthalmologist recommendation

08.01.03 Fluorouracil  Commissioned by NHSE
Hospital only
11.99.99.99 Fluorouracil 

Hospital only

13.08.01 Fluorouracil Efudix®
13.08.01 Fluorouracil 0.5% & salicylic acid 10% Actikerall®

For hyperkaratotic lesions

04.03.03 Fluoxetine 
04.03.03 Fluoxetine 
04.02.01 Flupentixol 

Supported by ESCA

04.02.02 Flupentixol Decanoate 

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

04.02.02 Fluphenazine Decanoate Modecate®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer 

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

Discontinued by UK manufacturer by the end of 2018

08.03.04.02 Flutamide 
03.02 Fluticasone 
  • Flixonase Nasal Drops
  • Flixotide Nebuliser Liquid
03.02 Fluticasone and salmeterol Seretide®

For paediatric use ONLY (i.e. up to 18 years of age)

  • Seretide Evohaler- 50mg and 125mg only .
  • Should be prescribed by the intended brand to ensure patients are maintained on the formulation they are used to.


How to use an Accuhaler Inhaler
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device

12.02.01 Fluticasone furoate Avamys®

Approved for use in children and adults

Previous APC decision reviewed in December 2015

12.02.01 Fluticasone furoate 

Hospital only

03.02 Fluticasone furoate & vilanterol Relvar Ellipta®



How to use an Ellipta Inhaler

03.02 Fluticasone Nasal Spray 

BRANDS

  • Flixonase
  • Nasofan
03.02 Fluticasone Nasal Spray Avamys®
03.02 Fluticasone propionate Flixotide®

 

  • Accuhaler
  • Evohaler

 

How to use an Accuhaler Inhaler
How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device

12.02.01 Fluticasone Propionate Flixonase Nasule®

Specialist recommendation only for nasal polyps

03.02.03 Fluticasone/vilanterol/Umeclidinium Trelegy Ellipta®
09.01.02 Folic Acid 

Green Traffic Light  Tablets 


  Sugar Free Solution Lexpec®

02.08 Fondaparinux Arixtra®

Hospital Only

09.04 Food First 

Where clinically appropriate encourage a nutrient dense food and fluid intake for patients at risk of malnutrition

09.04.02 Food First 

Where clinically appropriate encourage a nutrient dense food and fluid intake for patients at risk of malnutrition.

09.04 Foodlink® Complete 

First line product

  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Not suitable for CKD 4-5, renal pts.
  • Not suitable for lactose intolerance
  • Not suitable for bile acid malabsorption or fat maldigestion associated with biliary diseases/conditions
  • To be made up with whole milk
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04 Foodlink® Complete with Fibre 

First line with added fibre

  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Not suitable for CKD 4-5, renal pts.
  • Not suitable for lactose intolerance
  • Not suitable for bile acid malabsorption or fat maldigestion associated with biliary conditions
  • To be made up with whole milk
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
03.01.01.01 Formoterol Fumarate Oxis Turbohaler®



09.04.02 Fortini® 
  • More than 1 kcal/ml and less than 4g protein/100ml
  • Sip feed for children over 8kg with faltering growth
  • Disease-related malnutrition and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Fortini® Compact Multi Fibre 
  • Child: More than 1 kcal/mL and less than 4 g protein/100 mL
  • Low volume supplement
  • Supporting an unmet paediatric nutritional need
  • No other product is current available to meet this need
09.04.02 Fortini® Creamy Fruit 
  • Child: More than 1 kcal/mL and less than 4 g protein/100 mL
  • High energy fruit pudding for children with faltering growth
09.04.02 Fortini® Multi Fibre 
  • Child: More than 1 kcal/mL and less than 4 g protein/100 mL
  • Sip feed for children over 8kg with faltering growth, with added fibre
  • Disease-related malnutrition and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Fortini® Smoothie Multi Fibre 
  • Child: More than 1 kcal/mL and less than 4 g protein/100 mL
  • Sip feed for children over 8kg with faltering growth
09.04.02 Fortini®1.0 Multi Fibre 

Child under 12 years

  • 1 kcal/mL and less than 4g protein/100 mL
  • Standard 1 kcal/mL with fibre  
09.04 Fortisip® 
  • Restricted for use where fluid volume is a benefit
  • Restricted for patients who are lactose intolerant
  • Maybe used as an alternative as a bolus feeds
  • Low fibre
  • Low osmolality
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Low volume supplement and for bolus feeding
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
  • Second line choice for 200ml ready-made. If powder is not tolerated or contraindicated
09.04 Fortisip® 2kcal  
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • For bolus tube feeding only
  • Only on dietetic advice sip feed in small volum.
  • Nutritionally complete in 2 bottles
09.04 Fortisip® Bottle 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Restricted for use where fluid volume is a benefit
  • Restricted for patients who are lactose intolerant
  • Maybe used as an alternative as a bolus feeds
  • Low fibre
  • Low osmolality.
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
09.04 Fortisip® Compact 

Second line supplements choice

  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Low volume supplement and for bolus feeding
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
09.04 Fortisip® Compact Fibre 

Second line supplements choice for use when fibre in indicated as advised by dietitan only

  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Low volume supplement and for bolus feeding
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
09.04 Fortisip® Compact Protein 
  • More than 1.5 kcal/mL and 5 g (or more) protein/100 mL
  • Not to be used without dietetic advice that higher protein is clinically appropriate
  • With added protein
  • Low volume supplement and for bolus feeding advised by dietitian only
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula.
  • Not suitable for child under 3 years; use with caution in child 3–5 years.
09.04 Fortisip® Yogurt Style 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • For dysgeusia and flavour fatigue only
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years
09.04 Fortisip® Yogurt Style 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • For dysgeusia and flavour fatigue only
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for child under 3 years
05.03.01 Fosamprenavir Telzir®
05.03.02.02 Foscarnet Sodium 
05.03.02.02 Foscarnet Sodium Foscavir®
05.01.13 Fosfomycin 

Second line treatment for sensitivities

05.01.13 Fosfomycin Injection  

Hospital use only under microbiological advice 

04.07.04.02 Fremanezumab Ajovy®

In line with NICE

02.11 Fresh Frozen Plasma 
09.04 Fresubin 2 kcal Fibre Drink 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Used where 2kcal/ml sip feed in small volume with fibre is required
  • High Cal low Vol with added fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula ; also CAPD, haemodialysis.
  • Not suitable for use in child under 1 year; use with caution in child 1–5 years
09.04 Fresubin® 2 kcal Drink 

First line choice for 2kcal/ml sip feed

  • More than 1.5 kcal/mL and 5g (or more) protein/100 mlL
  • Small volume required and based on taste preference
  • Nutritionally complete in 2 bottles
  • High Cal low Vol
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula; also CAPD, haemodialysis.
  • Not suitable for use in child under 1 year; use with caution in child 1–5 years
09.04.02 Fresubin® HP Energy 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Only available product with high protein and high MCT (burns pts, tumour pts, and liver pts.)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula ; also CAPD and haemodialysis
09.04.02 Fresubin® HP Energy Fibre 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Only available product with high protein and high MCT with fibre (burns pts, tumour pts, liver pts)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04 Fresubin® Jucy Drink 
  • More than 1 kcal/mL and less than 5 g protein/100 mL
  • Juice style fat free, low K+
  • Patients who dislike milky tasting drinks 
  • Caution advised – not milk free and high sugar content
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula ; also CAPD, haemodialysis
09.04 Fresubin® Thickened 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Used for dysphagia pts only
  • Dysphagia or disease-related malnutrition. Not suitable for child under 3 years; use with caution in child 3–4 years.
09.04 Fresubin® YOcreme 
  • For dysgeusia and flavour fatigue only
  • Not recommended by SALTs for use as a dysphagia product
  • Low energy per serving as a semi-solid supplement where low volume is required only
09.04 Fructose 
  • Special additives for conditions of intolerance
  • Used as a partial CHO source in modular feeds for infants and children with malabsorption secondary to short bowel syndrome or other malabsorption states
  • (Laevulose) For proven glucose/galactose intolerance
09.06.07 FruitVits® 
  • For patients with inborn errors of metabolism and for enteral feed patients
  • For use in children 3 years and over with inborn errors of metabolism. This is a small volume, flavoured, carbohydrate free vitamin/mineral supplement used in conditions like citrin deficiency. There are no other carbohydrate free preparations available. It cannot be purchased from a supermarket. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Vitamin, mineral, and trace element supplement in children 3–10 years with restrictive therapeutic diets
08.03.04.01 Fulvestrant Faslodex®
02.02.02 Furosemide 
21 Furosemide  
  •  Syringe driver use for symptom management in heart failure at EOL

 

05.01.07 Fusidic acid 
11.03.01 Fusidic acid 

NICU Use as per guideline - 1st line

Bacterial conjunctivitis infection 2nd line per Antimicrobial Guidelines

13.10.01.02 Fusidic Acid 2% 
09.04 GA Amino 5 
  • Amino acid supplement without lysine – low in tryptophan for infants with GA1 - used for tube feeding in emergencies
  • The only pre-measured amino acid supplement without lysine, low in tryptophan for children with GA1 that can be administered via a tube in emergency feeds. It is essential it is easy to use in an emergency and pre-measured is safer, particularly for non-English speaking families. It can also be used in pyridoxine responsive epilepsy
09.04 GA Anamin Junior 
  • An unthickened amino acid supplement without lysine, low in tryptophan for children with GA1 that can be given as a drink. It can also be used in pyridoxine responsive epilepsy
09.04 GA Express 15 (not ACBS approved) 
  • Amino acid supplement without lysine and low in tryptophan for children and adults with GA1
  • The only low volume, vitamin and mineral amino acid supplement without lysine, low in tryptophan for use in patients > the age of 6 years’ children and adults with GA1 and pyridoxine responsive epilepsy
09.04 GA Gel® 
  • Amino acid supplement without lysine – low in tryptophan for infants with GA1
  • The only weaning (thickened) amino acid supplement without lysine, low in tryptophan for children with GA1. It can also be used in pyridoxine responsive epilepsy
  • Nutritional supplement for dietary management of type 1 glutaric aciduria in children 6 months–10 years
09.04 GA1 Anamix® Infant 
  • Amino acid supplement without lysine – low in tryptophan for infants with GA1
  • The only amino acid supplement without lysine, low in tryptophan for infants with GA1 and pyridoxine responsive epilepsy
  • Nutritional supplement for the dietary management of proven glutaric aciduria (type 1) in children from birth to 3 years
04.07.03 Gabapentin 

2nd line

Be aware of abuse and addiction potential associated with this class of agent

Due to the risk of adverse effects associated with Gabapentin,start with the lowest effective dose and titrate up to the minimum effective dose. Educate patient on titration
At follow up, check patient's tolerance of treatment and understanding of dose titration

See Gabapentin leave sheet for dose titration information

Reduce dose in renal impairment

04.08.01 Gabapentin 

On advice of specialist

Tablets £££££, capsules are more cost effective

MHRA Advice
For patients being treated for epilepsy , it is usually unnecessary to ensure that patiemts are maintained on a specific manufacturer's product unless there are specific reasons such as patient anxiety and risk of confusion or dosing errors

04.08.01 Gabapentin 

On advice of specialist

MHRA Advice
It is usually unnecessary to ensure that patients are maintained on a specific maufacturer's product unless there are specific reasons such as patient anxiety and risk of confusion or dosing errors

09.04 Galactomin 17® 
  • Specialised formulas: Infant and child: Residual lactose formula
  • Lactose free feed for use in adults metabolic disease only
  • Used as a milk alternative in adults, lactose free with galactosaemia. This is not used for infants by Birmingham Children’s Hospital. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Proven lactose intolerance in pre-school children, galactosaemia, and galactokinase deficiency
09.04 Galactomin 19® 
  • Specialised formulas: Infant and child: Fructose-based formula
  • Disease specific fructose containing formula for infants and children with glucose galactose malabsorption.
  • Conditions of glucose plus galactose intolerance
04.11 Galantamine 
  • Tablets
  • M/R capsules
  • Oral solution
04.07.04.02 Galcanezumab Emgality®

In line with NICE

A5.05.01 Gamgee UHB burns unit ONLY

Sterile or non sterile highly absorbent cotton wool enclosed in an absorbent cotton cover
Type of wound product is suitable for
Full thickness burns
Can be cut to required size
Secondary dressing
Duration dressing remains on wound before changing
Dependent on exudate levels
Frequency of dressing change
Dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used as a primary dressing
Only to be used in UHB burns unit
Rationale for inclusion in formulary
UHB burns unit only

05.03.02.02 Ganciclovir 
05.03.02.02 Ganciclovir Cymevene®
11.03.03 Ganciclovir  Virgan®

Use on specialist ophthalmologist recommendation

01.01.02 Gaviscon Infant 

Oral powder

08.01.05 Gefitinib Iressa®

Commissioned by NHSE

09.02.02.02 Gelatin Gelofusine®

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

12.03.01 Gelclair® 

Oncology & haematology use only

20 Gelofusion and indigocarmine for submucosal injection for endoscopic mucosal resection 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

08.01.03 Gemcitabine Gemzar®

Commissioned by NHSE
Hospital only

07.01.01 Gemeprost  For Specialist/ Hospital Use Only
08.02.03 Gemtuzumab ozogamicin Mylotarg®

Hospital use only

In line with NICE

03.13 Gentamicin 
03.13 Gentamicin 

Hospital only

05.01.04 Gentamicin 

For hospital use only

11.03.01 Gentamicin 

Possible second line after chloramphenicol on specialist ophthalmologist recommendation

11.03.01 Gentamicin  

For the treatment of corneal abscess only on specialist ophthalmologist advice.

12.01.01 Gentamicin 0.3% Genticin®

Only with positive culture/sensitivity data

08.01.05 Gilteritinib  Xospata®

In line with NICE

08.02.04 Glatiramer Acetate Copaxone®

Hospital use only

05.03.03.02 Glecaprevir-pibrentasvir Maviret®

In line with NICE

06.01.02.01 Gliclazide 
  • Tablets
  • Modified Release Tablets

Check OptimiseRx for most cost effective brand

06.01.02.01 Glimepiride 
06.01.04 Glucagon GlucaGen® HypoKit
06.01.04 GlucoGel® 
06.01.04 Glucose  
06.01.04 Glucose 

Green

  • Dextrogel 

 

06.01.04 Glucose 
09.04 Glucose 
  • Special additives for conditions of intolerance
  • Used as a partial CHO source in modular feeds for infants and children with malabsorption secondary to short bowel syndrome or other malabsorption states
  • (Dextrose monohydrate) For use as an energy supplement in sucrose-isomaltase deficiency
21 Glucose 4% and Sodium Chloride 0.18% 
06.01.06 Glucose interstitial fluid detection sensors FreeStyle Libre 2 Sensor ®

Green in Type I Diabetes

Amber Recommendedin Type II Diabetes in line with RMOC criteria

09.02.02.01 Glucose Intravenous 

Hospital use only

09.08.01 Glutamine 
13.07 Glutaraldehyde 10% 

Over the counter preparation suitable for self-care/purchase if appropriate

09.04.01 Gluten Free Foods 

Department of Health and Social Care (DHSC) guidance – 

  • GF, GF & Wheat Free (WF) bread (includes rolls, part baked bread, and pizza bases)
  • GF, GF&WF mixes

Follow Coeliac UK prescribing guidance for monthly quantities (based on age)

01.06.02 Glycerol (Glycerin) Suppositories 
01.07.04 Glyceryl Trinitrate 0.4% Ointment Rectogesic®
02.06.01 Glyceryl Trinitrate 400mcg/ dose Spray 




02.06.01 Glyceryl trinitrate buccal 
02.06.01 Glyceryl Trinitrate Injection 

Secondary Care use only

02.06.01 Glyceryl Trinitrate Sublingual tablets 
02.06.01 Glyceryl Trinitrate Transdermal Patches 
07.04.04 Glycine 

For Specialist / Hospital Use Only

13.14.07 Glycopyrrolate 0.05% w/v in water 
13.14.07 Glycopyrrolate 2% w/w in cetomacrogol cream 
13.12 Glycopyrronium 

Unlicensed

Specialist initiation for hyperhidrosis

15.01.03 Glycopyrronium 

HOSPITAL ONLY

21 Glycopyrronium  
04.12 Glycopyrronium bromide Sialanar®

£££££

Specilaist initiation and stabilisation

Approved on formualry December 2017

03.01.04 Glycopyrronium/formoterol Bevespi Aerosphere®
09.04 Glycosade® 
  • Slow release CHO to prevent hypoglycaemia in GSD
  • The only specially formulated slow release carbohydrate to prevent hypoglycaemia in severe forms of GSD e.g. Type I and III which allows extended fasting time. The dosage is dependent on age, weight and clinical symptoms of hypoglycaemia. Doses may be given at regular intervals during the day and night or at bedtime only. The dose and frequency of dose should always be advised by the specialist dietitian according to the needs of the patient. Glycosade is in a pre-measured sachet. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • A nutritional supplement for use in the dietary management of glycogen storage disease and other metabolic conditions where a constant supply of glucose is essential. Not suitable for use in children under 2 years
09.04 Glytactin Bettermilk 15 
  • A low phenylalanine supplement derived from whey protein for children and adults with phenylketonuria. It is more palatable than amino acid supplements and associated with better utilisation of protein. Very useful for adult patients trying to return to diet or children / adults struggling to take their amino acid product because of its taste. Suitable from aged 4 years
09.04 Glytactin Bettermilk RTD 15 (original and chocolate) 
  • A low phenylalanine supplement derived from whey protein for children and adults with phenylketonuria. It is more palatable than amino acid supplements and associated with better utilisation of protein. Very useful for adult patients trying to return to diet or children / adults struggling to take their amino acid product because of its taste. Suitable from aged 4 years
01.05 Golimumab Simponi®

Specialist use only in line with NICE TA

10.01.03 Golimumab Simponi®

Hospital only

Available via Home Care

 

06.05 GONADORELIN 

HRF - Red

Powder For - Red

06.07.02 Goserelin 

 

  BRANDS

  •  Zodalex 
  •  Zodalex LA
08.03.04.02 Goserelin Zoladex®

Advanced prostate cancer

08.03.04.02 Goserelin Zoladex® LA

Advanced prostate cancer

A5.09.01 Graduated compression hosiery 

Based on assessment

04.06 Granisetron Sancuso®

Hospital use only for oncology patients

04.06 Granisetron 

Hospital only

A5.02.04 Granuflex® 

Specialist recommendation only

Type of wound product is suitable for
Hyperkeratosis, granulating wounds, forms cohesive gel on contact with exudate

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
3-7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to ingredients - contains pectin and gelatine
Not for diabetic foot ulcers or ischaemic wounds
Not for infected wounds

Rationale for inclusion in formulary
Comformable waterproof dressing, aids rehydration.
Reduces and softens hyperkeratosis

03.04.02 Grass and Tree Pollen Extract Pollinex® For hospital use only
03.04 Grass pollen extract Pollinex ®
03.04 Grass pollen extract Grazax®
05.02.05 Griseofulvin 
09.04 GTO oil 
  • A cooking oil for dietary treatment of adrenoleukodystrophy. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
04.04 Guanfacine Intuniv®

For the treatment of ADHD in children and adolescents 6-17 years old for whom stimulants are not suitable, not tolerated or have been shown to be ineffective

13.05.03 Guselkumab Tremfya®

In line with NICE

14.04 Haemophilus Type B Menigococcal Group C Conjugate Vaccine Menitorix®
01.07.01 Haemorrhoid relief ointment 
01.07.01 Haemorrhoid relief suppositories 
04.02.01 Haloperidol 

For rapid tranquilisation

Not to be used for psychiatric / anxiolytic purposes in Primary Care

04.02.01 Haloperidol 

Dot tablets
Dot capsules
Dot SF liquid
Dot Supported by an ESCA

04.02.02 Haloperidol Haldol Decanoate®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer 

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

04.09.03 Haloperidol 
09.04 HCU Anamix® Infant 
  • Amino acid supplement without methionine for infants with homocystinuria
  • The only amino acid supplement without methionine for infants with homocystinuria. It is given to screened infants for HCU. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Nutritional supplement for the dietary management of proven vitamin B6 non-responsive homocystinuria or hypermethioninaemia in children from birth to 3 years
09.04 HCU cooler® 10 
  • Amino acid supplement without methionine for children and adults with homocystinuria
  • The only liquid amino acid supplement without methionine for children with homocystinuria aged 3 to 6 years. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
09.04 HCU cooler® 15 
  • Amino acid supplement without methionine for teenagers and adults with homocystinuria
  • The only liquid amino acid supplements without methionine for children with homocystinuria aged 7 to 12 years. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
09.04 HCU cooler® 20 
  • Amino acid supplement without methionine for teenagers and adults with homocystinuria
  • One of two liquid amino acid supplements without methionine for children with homocystinuria aged >12 years. They need the larger sachets (20g protein equivalent) meet their non-methionine protein requirements
09.04 HCU Express® 15 
  • Amino acid supplement without methionine for teenagers and adults with homocystinuria
  • The only powdered amino acid supplement without methionine that provides 15g protein equivalent per sachet for children with homocystinuria aged 7 to 12 years. Larger sachets are unacceptable for this age group of children and provide in excess of protein requirements
  • A methionine-free protein substitute for use as a nutritional supplement in children over 8 years with homocystinuria
09.04 HCU Express® 20 
  • Amino acid supplement without methionine for teenagers and adults with homocystinuria
  • One of 2 powdered amino acid supplements without methionine that provides 20g protein equivalent per sachet for teenagers with homocystinuria aged >12 years. They need the larger pouches to meet their non-methionine protein requirements. It is important we have a choice of more than 1 product for this age group as adherence is poor
  • A methionine-free protein substitute for use as a nutritional supplement in children over 8 years with homocystinuria
09.04 HCU gel® 
  • Amino acid supplement without methionine for children with homocystinuria
  • The only weaning (thickened) amino acid supplement without methionine for children with homocystinuria
  • A methionine-free protein substitute for use as a nutritional supplement for the dietary management of children 1–10 years with homocystinuria
09.04 HCU Lophlex® LQ 20 
  • Amino acid supplement without methionine for teenagers and adults with homocystinuria
  • One of 2 powdered amino acid supplements without methionine that provides 20g protein equivalent per sachet for teenagers with homocystinuria aged >12 years. They need the larger pouches to meet their non-methionine protein requirements. It is important we have a choice of more than 1 product for this age group as adherence is poor
  • Nutritional supplement for the dietary management of homocystinuria in children over 3 years
09.06.07 Healthy Start Vitamins 

Available free of charge from designated centres.

01.03 Helicobacter Stool Antigen Test 

In line with NICE / PHE guidance 

Check availability of test in local laboratory

01.03 Helicobacter Urea Breath Test 

In line with NICE / PHE guidance

02.08.01 Heparin Sodium 
13.13 Heparinoid 0.3% Hirudoid®
14.04 Hepatitis A and Typhoid ViATIM®
14.04 Hepatitis A vaccine Paediatric Single Component HAvrix ® Junior Monodose, VAQTA ® Paediatric
14.04 Hepatitis A vaccine Single Component Havrix ® Monodose, AVAXIM ®, VAQTA ® Adult
14.04 Hepatitis A vaccine with Hepatitis B vaccine  Twinrix® Adult, Twinrix® Paediatric, Ambirix®
14.05.02 Hepatitis B immunoglobulin 
14.04 Hepatitis B vaccine Single Component Engerix B® Fendrix® HBvaxPRO®
13.11.02 Hibitane Obstetric® 
13.10.05 Histoacryl® 

Hospital only

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

20 Histoacyl and lipiodol for gastric varices 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

09.04 Homemade milkshake 

Where clinically appropriate encourage a standardised home-made nutritious drink at least equivalent to a standard 1.5KCal/ml prescribed bottle supplement in terms of calories and protein

09.04.02 Homemade milkshake 

Where clinically appropriate encourage a standardised home-made nutritious drink equivalent to a standard 1.5 KCal/mL prescribed bottle supplement in terms of calories and protein.

03.04 House dust mite extract Mitizax®
03.04 House dust mite extract Acarizax®
06.05 Human Chorionic Gonadotrophin 

HUMAN MENOPAUSAL GONADOTROPHINS - Red

HUMAN MENOPAUSAL GONADOTROPHINS / Menogon - Red

02.11 Human fibrinogen / Human thrombin Evicel®
09.08.02 Human hemin Normasang® NHSE commissioned
12.04 Human papilloma virus vaccine  Gardasil®

For use by ENT Specialists in recurrent respiratory papillomatosis (RRP) 

14.04 Human papilloma virus vaccine Gardasil®, Gardasil®9
14.04 Human Papilloma virus vaccine Cervarix ®

Use Gardasil first line

14.04 Human papolloma virus vaccine 

For use by ENT Specialist only in recurrent respiratory papillomatosis (RRP)

11.99.99.99 Hyaluronidase Hyalase®

Hospital only

02.05.01 Hydralazine 
01.05.02 Hydrocortisone 
06.03.02 Hydrocortisone  

 

  • SODIUM SUCCINATE
  • SODIUM PHOSPHATE

 

06.03.02 Hydrocortisone  

 

13.04 Hydrocortisone 0.25% Crotamiton 10% Eurax-Hydrocortisone®

Potency-mild

Post scabies once infection cleared but itch still present.

13.04 Hydrocortisone 0.5% 

Dot Potency-mild
Dot Cream
Dot Ointment

13.04 Hydrocortisone 0.5% ,chlorhexidine HCl 1% & nystatin Nystaform-HC®

Potency - mild

Paediatric use only

Replacement for discontinued Vioform HC

13.04 Hydrocortisone 1% 

Dot Potency-mild
Dot Cream
Dot Ointment

13.04 Hydrocortisone 1% and oxytetracycline 3% Terra-Cortril® ointment

Potency-mild

13.04 Hydrocortisone 1% with Clotrimazole 1% Canesten HC®

Potency-mild

13.04 Hydrocortisone 1% with Miconazole Nitrate 2% Daktacort® cream

Potency-mild

12.03.01 Hydrocortisone 2.5mg 

Specialist recommendation only

10.01.02.02 Hydrocortisone acetate Hydrocortistab®

For hospital use

13.04 Hydrocortisone Acetate 1% with Fusidic Acid 2% Fucidin H® cream

Potency-mild

12.01.01 Hydrocortisone Acetate 1% with Gentamicin 0.3% Gentisone® HC

Only with positive culture/sensitivity data

13.04 Hydrocortisone Butyrate 0.1% Locoid®

Potency - potent

Dot Cream
Dot Lipocream
Dot Ointment
Dot Scalp lotion

01.05.02 Hydrocortisone foam enema Colifoam ®

For specialist initiation

Foam enema 125mg /metered application

 

01.07 Hydrocortisone with lidocaine 
A5.02.02 Hydrofilm® 

Preferred local option

Vapour-permeable adhesive film

Type of wound product is suitable for
Dry non infected wounds, retention of lines, fixation of secondary dressings, protection of intact skin, protection of skin against friction, protection of newly epithelialized wounds

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Clinically infected wounds, bleeding or exuding wounds

Rationale for inclusion in formulary
Retention of lines, protection of intact skin, fixation of other dressings. Cost effective
Waterproof

12.03.04 Hydrogen peroxide mouthwash BP
13.11.06 Hydrogen peroxide Crystacide®
13.11.06 Hydrogen Peroxide Solution  

Dot 3% (10 vols)
Dot 6% (20 vols)

09.04 Hydrolysed whey protein maltodextrin powder 
  • High-energy supplements: protein
  • Hydrolysed protein powder to be used in a modular feed
13.02.01 Hydromol® 

Over the counter preparation suitable for self-care/purchase if appropriate

13.02.01 Hydromol® 

Over the counter preparation suitable for self-care/purchase if appropriate

13.02.01.01 Hydromol® Bath and Shower Emollient 

Over the counter preparation suitable for self-care/purchase if appropriate

13.14.07 Hydroquinone 5% w/w, hydrocortisone 1% w/w & tretinoin 0.1% w/w in a non-aqueous gel 0.3% w/v 
13.02.01 Hydrous ointment BP 

Over the counter preparation suitable for self-care/purchase if appropriate

09.01.02 Hydroxocobalamin 
08.01.05 Hydroxycarbamide 

For myeloproliferative disorders

Supported by an ESCA (in developement)

Fopr use in sickle cell - see Chapter 9

09.01.03 Hydroxycarbamide 

For use in sickle cell.

13.05.03 Hydroxycarbamide 
10.01.03 Hydroxychloroquine 

Please note: ESCA is not required - Common practice

10.01.03 Hydroxychloroquine 
13.05.03 Hydroxychloroquine 
03.04.01 Hydroxyzine  
11.08.01 HYLO NIGHT® Formally known as VitA POS®

Name change from VitA POS to HLYO NIGHT (April 2020)

04.02.03 Hyoscine 

For hypersalivation caused by antipsychotics in line with Green status for hypersalivation use in Parkinson's Disease

01.02 Hyoscine Butylbromide 

10mg Tablet 

20mg/ml Injection

04.06 Hyoscine Hydrobromide 
15.01.03 Hyoscine Hydrobromide 
15.01.03 Hyoscine hydrobromide 
15.01.03 Hyoscine hydrobromide 

For hyoscine patch, see Chapter 4.6

21 Hyoscine Hydrobromide  
  •  Not used as frequently in palliative care due to side-effects and cost.

 

21 Hyoscine Hydrobromide 
  •  Indictaion " drooling in chronic neurological disease".
04.06 Hyosine Scopaderm

£££££

1.5mg patch releases 1mg of hyoscine over 72 hours

Tablets more cost effective

03.07 Hypertonic sodium chloride 

VIALS

AMPOULES

  • Bronchlear 3%
  • Mucoclear 3%
  • Nebusal 7%
  • Pulmoclear 3%
  • Pulmoclear 7%
  • Resp-ease 3%
  • Resp-ease 7%
  • Respi-clear 7%
  • Salineb 7%
11.08.01 Hypromellose 0.5% 

All other strengths are non-formulary

06.06 Ibandronic acid 

Dudley

Black 

Sandwell

Amber SC

ESCA Sandwell only

Walsall

 Green

Wolverhampton 

Red

 

06.06 Ibandronic acid 
06.06 Ibandronic acid 
08.01.05 Ibrutinib Imbruvica®

In line with NICE

Hospital ONLY - NHSE commisssioned

02.14 Ibuprofen Pedea®
10.01.01 Ibuprofen 

This remains the first-line NSAID. If a patient has tried ibuprofen, check that they have taken an anti-inflammatory dose at least 400mg TDS regularly.

Also indicated for use in dysmenorrhoea.

Suspension is reserved for paediatric use, patients with swallowing difficulties or specific clinical need.

The lowest effective dose should be used for the shortest duration necessary to control symptoms. A patient’s need for symptomatic relief and response to treatment should be re-evaluated periodically.

10.01.01 Ibuprofen 

For patients with swallowing difficulties

Paediatric use

10.03.02 Ibuprofen 5 % gel 

Prescribe generically. Follow Optimise Rx advice for any preferred brand

03.04.03 Icatibant Firazyr®

Hospital only- NHSE Commissioned

13.14.04 Ichthammol 1% w/w & zinc oxide 15% w/w in YSP 
A5.08.09 Ichthopaste 

Preferred local option

Specialist recommendation only
Zinc and Ichthammol bandage.
Type of wound product is suitable for
Venous leg ulcers Chronic eczema Dermatitis
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
Daily up to weekly dependant on skin and wound management.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use in any cases of sensitivity or allergy to ingredients
Rationale for inclusion in formulary
For treatment of dermatitis and chronic eczema when
venous insufficiency is present.

02.12 Icosapent ethyl 
19.49 Icthopaste®  Zinc Paste Bandage has been used with compression bandaging for the treatment of venous leg ulcers. However, paste bandages are associated with hypersensitivity reactions and should be used with caution.
08.01.02 Idarubicin Hydrochloride 

Commissioned by NHSE
Injection-hospital only

02.08 Idarucizumab  
08.01.05 Idelalisib Zydelig®

NHSE is responsible commissioner for its use in chronic lymphocytic leukaemia (as per NICE TA359)

09.08.01 Idursulfase Elaprase® NHSE commissioned
08.01.01 Ifosfamide 

Commissioned by NHSE
Hospital only

02.05.01 Iloprost 
02.05.01 Iloprost nebules Vantavis®

NHS England commissioned 

08.01.05 Imatinib Glivec®

Commissioned by NHSE

In line with NICE

05.01.02.02 Imipenem with Cilastatin Primaxin®

For hospital use only

05.01.02.02 Imipenem with Cilastatin 

For hospital use only

05.01.02.02 Imipenem with cilastatin and relebactam Recarbrio®
04.03.01 Imipramine 
13.07 Imiquimod Aldara®
13.08.01 Imiquimod 3.75% Zyclara®

For field changes >25cm2

13.08.01 Imiquimod 5% Aldara®
14.04 Inactivated Influenza Vaccine 
19.21 Inadine® Povidine-Iodine Dressing. Indications: sloughy, exuding wounds. Bactericidal and are very effective against MRSA. Need secondary dressings.
CAUTION: hyperthyroidism, concurrent lithium therapy, severe renal impairment – discuss with GP first before prescribing. Contra-indications: known or suspected iodine sensitivity, not recommended for use in children or in pregnancy or lactation.Iodine may be absorbed particularly if large wounds treated.
NB: Destroyed by sloughy exudate. Max 4 dressings
at same time. Orange goes to white antimicrobial
activity is reduced after 2 days.
Superficial/low to moderate exuding infected wounds
A5.03.02 Inadine® 

Preferred local option

Non-adherent dressing impregnated with povidone iodine (10%)

Type of wound product is suitable for
Mild local infection where there is low exudate levels, ischaemic wounds, dry, gangrenous digits with the aim to desiccate and auto-amputate.
Dry-manage fixator sites
Minor burns or skin trauma with local infection

Duration dressing remains on wound before changing
1-3 days depending on uptake of iodine from dressing

Frequency of dressing change
1-3 days depending on uptake of iodine from dressing
Look at colour change of dressing (orange initially to white when all used)

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Iodine allergy or sensitivity
Thyroid disorders
Renal impairment
Not suitable for children, pregnant or lactating women

Rationale for inclusion in formulary
Topical antimicrobial
Non-adherent/pain free use
No damage to granular or epithelial cells
Easy application and removal
Drying properties
Efficacy against bacteria, fungi and viruses
Cost effective.

02.12 Inclisiran Leqvio®

Inclisiran is covered by NICE TA 733.

02.02.01 Indapamide 

Use 2.5mg standard release tablets only.

02.02.01 Indapamide MR 
13.10.05 Indermil® 

Hospital only

20 Indigo carmine 

For use by endoscopy only

06.04.01.01 Indivina® 
02.14 Indometacin Indocid PDA®
10.01.01 Indometacin 

For use in gout and resistant cases

10.01.01 Indomethacin 

£££££

Special product (100ml)

For use in gout and special cases

20 Infacol and N acetyl cysteine for mucosal cleansing 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

14.04 Infanrix-IPV® 
09.04 Infatrini®  
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • 1 kcal infant feed for faltering growth
  • Varying volume size available to support nutritional requirements of the patients
  • Single use only in acute setting – risk of increased waste. Once open must be used within 24 hours
  • Failure to thrive, disease-related malnutrition and malabsorption, in child from birth up to body-weight 8 kg. Up to 18 months
09.04 Infatrini® Peptisorb 
  • Infant and child: Hydrolysate formula
  • Whey hydrolysate. Use in infants (birth – 18 mths) who are unable to tolerate Infatrini (eg gut intolerance) and also require a higher calorie feed for faltering growth
  • Use as tube or oral feed
  • Disease-related malnutrition, intractable malabsorption, proven inflammatory bowel disease, short bowel syndrome, bowel fistula, and intolerance to whole protein feeds
01.05.03 Infliximab Remicade®

For specialist use only in line with NICE guidance

Commissioned in paediatrics by NHSE

£££££

10.01.03 Infliximab 

Hospital use only

Biosimilar brands of Remicade available:

  • Flixabi®
  • Inflectra®
  • Remsima®
  • Zessly®

Paediatric use is commissioned by NHSE

14.04 Influenza vaccine Fluenz Tetra®
06.01.01.03 Injection Devices 
  • AllStar Pro hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-80 units
  • Autopen
  • Autopen 24 hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-21 units
  • Autopen 24 hypodermic insulin injection pen reusable for 3ml cartridge 2 unit dial up / range 2-42 units
  • Autopen Classic hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-21 units
  • Autopen Classic hypodermic insulin injection pen reusable for 3ml cartridge 2 unit dial up / range 2-42 units
  • HumaPen Ergo
  • HumaPen Luxura
  • HumaPen Luxura HD hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 1-30 units
  • HumaPen Savvio hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-60 units
  • JuniorSTAR hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 1-30 units
  • NovoPen
  • NovoPen 5 hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-60 units
  • NovoPen Echo hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 0.5-30 units
  • OptiPen Pro 1
  • mhi-500
05.03.02.01 Inosine Pranobex Imunovir®
08.02.03 Inotuzumab ozogamicin Besponsa®

Hospital use only

In line with NICE

06.01.01.01 Insulin 
  • Actrapid
  • Humulin S
  • Insuman Rapid
06.01.01.01 Insulin  Humulin R 500 units in 1mL®
06.01.01.01 Insulin Aspart  

Green

  • Fiasp
  • Fiasp FlexTouch
  • Fiasp Penfill
  • NovoRapid
  • NovoRapid FlexPen
  • NovoRapid FlexTouch
  • NovoRapid Penfill
  • Trurapi

Amber Recommended 

  • NovoRapid PumpCart
06.01.01.02 Insulin Degludec Tresiba®

 

  • Tresiba FlexTouch 100units/ml
  • Tresiba Penfill 100units/ml
06.01.01.02 Insulin Degludec Tresiba Flextouch ®

 

  • Tresiba FlexTouch 200units/ml

 Green Type I Diabetes

Amber Recommended Type II Diabetes

06.01.01.02 Insulin degludec/liraglutide 
06.01.01.02 Insulin Detemir 
  • Levemir FlexPen
  • Levemir InnoLet
  • Levemir Penfill
06.01.01.02 INSULIN GLARGINE 

 

  • Abasaglar KwikPen
  • Lantus
  • Toujeo
  • Toujeo DoubleStar
06.01.01.02 Insulin glargine Semglee®

First line insulin for new patients initiated on insulin glargine 100units/ml and existing patients on Lantus

06.01.01.01 Insulin Glulisine 

BRANDS

  • Apidra
  • Apidra SoloStar
06.01.01.01 Insulin lispro 

BRANDS

  • Humalog Junior KwikPen
06.01.01.02 Insulin Lispro 
  • Admelog
  • Humalog 100units/ml
  • Humalog KwikPen
  • Lyumjev
  • Lyumjev KwikPen
  • Lyumjev Junior KwikPen
06.01.01.03 Insulin Pen Needles Insupen 4mm/32g pen needles

 

 

06.01.01.03 Insulin Pen Needles Insupen 5mm/31g pen needles

 

 

06.01.01.03 Insulin Pen Needles BD Viva 4mm/32g pen needles

 

 

06.01.01.03 Insulin Pen Needles GlucoRx Carepoint 5mm/31g pen needles

 

 

06.01.01.03 Insulin Pen Needles BD Viva 5mm/31g pen needles

 

 

06.01.01.03 Insulin Pen Needles Microdot MAX safety pen needles 5mm/30g ®

There are used primarily to protect any individuals administering insulin as a third party

 

 

08.02.04 Interferon Alfa 

Hospital only

In line with NICE

08.02.04 Interferon alfa-2a Roferon-A ® Commissioned by NHSE for the treatment of Hepatitis B and C
Hospital only
08.02.04 Interferon alfa-2b IntronA ® Commissioned by NHSE for the treatment of Hepatitis B and C
Hospital only
08.02.04 Interferon Beta Avonex®
08.02.04 Interferon Beta Betaferon®
08.02.04 Interferon Beta Proleukin®
08.02.04 Interferon Beta Rebif®
08.02.04 Interferon beta Extavia®
08.02.04 Interferon gamma-1b Immukin ®

Hospital only

14.05 INTERFERON GAMMA-1b 
28.01 Intrathecal Fluorescein Sodium 

For diagnosis of CSF leak

07.03.04 Intra-uterine Contraceptive Devices T-Safe® CU 380 A QuickLoad
07.03.04 Intra-uterine Contraceptive Devices Mini TT® 380 Slimline
07.03.04 Intra-uterine Contraceptive Devices  Nova-T® 380
07.03.02.03 Intra-uterine Progestogen Only System Mirena®
  • GP will not prescribe for supply. Only prescribe if fitting
  • Effective for 5 years
07.03.02.03 Intra-uterine Progestogen Only System Kyleena®
  • Prescribe by brand name to reduce risk of confusion between products
  • Low-dose levonorgestrel releasing IUS effective for 5 years
07.03.02.03 Intra-uterine Progestogen Only System Jaydess®

•GP will not prescribe for supply. Only prescribe if fitting
•Effective for 3 years

06.02.02 Iodine and Iodide 
A5.03.02 Iodoflex 

Cadexomer dressing containing iodine

Preferred local option

Type of wound product is suitable for
Iodine paste in mesh form for chronic infected, sloughy wounds with moderate exudate eg pressure ulcers, leg ulcers, diabetic foot ulcers
Can be used under compression bandaging

Duration dressing remains on wound before changing
Up to 3 days

Frequency of dressing change
Daily for acute infection
Up to 3 days for chronic wounds and infection, depending on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or sensitivity to iodine
Precaution with large wounds due to absorption. Do not use more than 50g in a single application and no more than 150g in 7 days
Dry necrotic wounds
Thyroid disorders
Renal impairment
Not suitable for children, pregnant or lactating mothers
Concurrent Lithium therapy

Rationale for inclusion in formulary
Anti microbial, broad spectrum, long acting/high absorption capacity
Removes slough and debris to clean the wound bed
Can be moulded to shape of the wound
Alternative to honey products if allergy to bees

19.21 Iodoflex®  Indications: sloughy, exuding wounds. Bactericidal and are very effective against MRSA. Need secondary dressings. Moderate to highly exuding infected wounds.
CAUTION: hyperthyroidism, concurrent lithium therapy, severe renal impairment – discuss with GP first before prescribing. Contra-indications: known or suspected iodine sensitivity, not recommended for use in children or in pregnancy or lactation.
Iodine may be absorbed, particularly from large wounds or during prolonged use.
Single Use = 50g
Weekly = 150g
3 months MAX
A5.03.02 Iodosorb 

Preferred local option

Cadexomer powder or ointment with iodine

Type of wound product is suitable for
Chronic exuding sloughy wounds eg leg ulcers, pressure ulcers, diabetic foot ulcers. Can be used under compression bandaging

Duration dressing remains on wound before changing
Up to 3 days

Frequency of dressing change
Daily for acute infection
Up to 3 days for chronic infection

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to iodine products
Dry necrotic tissue
Not suitable for Children, pregnant or lactating mothers
Thyroid disorders
Renal impairment
Needs at least twice weekly dressings for iodine to be effective

Rationale for inclusion in formulary
Antimicrobial, broad spectrum, long acting
De-slough and cleans wound debris
Non-adherant. Reduces trauma to wound and pain on dressing changes
Easy application. Can fill cavities or awkward shaped wounds
Alternative to honey based products if allergy to bees

08.01.05 Ipilimumab Yervoy®

Commissioned by NHSE
Hospital only

03.01.02 Ipratropium bromide 

 

  • Ipratropium
  • Atrovent Udv
02.05.05.02 Irbesartan 
06.01.02.03 Irbesartan 
09.01.01.01 Iron and Folic Acid Pregaday®
09.01.01.02 Iron isomaltoside Monofer®

Hospital only

09.01.01.02 Iron Sucrose Venofer®

Hospital use only

A5.12 Irripod 

Preferred local option

Sterile sodium chloride solution
Type of wound product is suitable for
Wound cleansing, for topical irrigation of the eye
Duration dressing remains on wound before changing
As required
Frequency of dressing change
As required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Single use
External use only
Rationale for inclusion in formulary
Cost effective
Cleansing of wounds

08.01.05 Isatuximab  

In line with NICE

05.02.01 Isavuconazole 
15.01.02 Isoflurane 

HOSPITAL ONLY

15.01.02 Isoflurane AErrane®

HOSPITAL ONLY

09.04 Isoleucine 1000® 
  • Used as an inpatient only
  • Used at the time of diagnosis when on haemofiltration and an isoleucine supplement is necessary
09.04 Isoleucine50® 
  • To correct isoleucine deficiency in MSUD
  • The only pre-measured sachet of isoleucine that provides 50 mg/dose to correct isoleucine deficiency in MSUD. A pre-measured sachet is particularly important as most of our families with MSUD do not speak English as their first language so require pre-measured products. The dose and frequency of administration will be determined by the specialist dietitian
  • Nutritional supplement for use in the dietary management of inborn errors of amino acid metabolism in adults and children from birth
05.01.09 Isoniazid 

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Isoniazid  Unlicensed special.
06.01.01.02 Isophane Insulin 

 

  • Humulin I
  • Humulin I KwikPen
  • Insulatard
  • Insulatard InnoLet
  • Insulatard Penfill
  • Insuman Basal
  • Insuman Basal SoloStar

 

 

02.07 Isoprenaline 
02.06.01 Isosorbide Dinitrate 
02.06.01 Isosorbide Mononitrate  

Brand prescribe modified release preparations

Follow Optimise Rx advice for new initiations

 

02.06.01 Isosorbide Mononitrate 
09.04 Isosource Junior® 
  • Isosource® Junior Mix is a nutritionally complete 1.2kcal/ml standard enteral tube feed, containing some blended food ingredien (rehydrated Chicken meat & vegetables, peach puree, orange juice from concentrate).

  • Indicated for: Short bowel syndrome; intractable malabsorption; preoperative preparation of undernourished patients; inflammatory bowel disease; total gastrectomy; dysphagia; bowel fistulae; feeding intolerances, developmental disabilities, disease related malnutrition for children greater than 1 year of age
13.06.02 Isotretinoin  Oral retinoid should only be prescribed under the supervision of a consultant dermatologist.
Contraindicated in pregnancy.
01.06.01 Ispaghula Husk 

Follow Optimise Rx recommendation on which brand to choose

Adequate fluid intake is important to prevent obstruction (6-8 cups per day) and should not be taken immediatley before bed

Unsuitable for frail patients who are likely to drink less than daily required volume of fluid

Fluid thickens on standing so should be taken as soon as possible after mixing

Time to effect is approximately 48-72 hours

05.02.01 Itraconazole oral presentations

Capsules more cost effective

SF Liquid £££££

05.02.01 Itraconazole 
A5.02.02 IV3000 

Specialist recommendation only
Fixation dressing
Type of wound product is suitable for
For fixation of intravenous and subcutaneous catheter sites
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
Up to 7 days or when wet/soiled
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Sensitivity to any of the product components
Not for use on pressure ulcers, burns or donor sites
Strips and documentation label are not to be used as suture replacements or primary wound closure methods
Rationale for inclusion in formulary
Fixation of intravenous and subcutaneous devices

09.04 IVA Anamix® Infant 
  • Amino acid supplement without leucine for infants with isovaleric acidaemia
  • The only infant amino acid supplement without leucine, for infants with isovaleric acidaemia. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Nutritional supplement for the dietary management of proven isovaleric acidaemia or other proven disorders of leucine metabolism in children from birth to 3 years
02.06.03 Ivabradine 

For use on the advice of a specialist in line with NICE TA267 

 

03.07 Ivacaftor Kalydeco®

In line with NICE

05.05 Ivermectin 

Unlicensed, for crusted scabies, on specialist advice

13.06.03 Ivermectin Soolantra®

For topical treatment of inflammatory lesions of rosacea (papulopustular) in adults.
Alternative treatment option to metronidazole 0.75% cream/gel or azelaic acid 15% gel 

05.05 Ivermectin > Soolantra 
08.01.05 Ixazomib 

In line with NICE

Hospital only - NHSE commissioned

08.01.05 Ixazomib Ninlaro®
13.05.03 Ixekizumab Taltz®

In line with NICE

A5.17 Jelonet®  Hospital use only
Paraffin gauze dressing
Type of wound product is suitable for
As a primary layer for use with Flamazine® or Flammercerium®
Duration dressing remains on wound before changing
24 hours
Frequency of dressing change
Daily- occasionally alternate day
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to any ingredients.
Rationale for inclusion in formulary
Cost effective primary layer
09.04.02 Jevity® 
  • 1 kcal/ml and less than 5g protein/100ml
  • Pt requires 1 kcal/ml vegetarian feed fish oil free (contains fibre)
  • Standard ACBS indications: Disease -related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula except bowel fistula. Not suitable for child under 2 years
09.04.02 Jevity® 1.5kcal 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High energy vegetarian feed, fish oil free with fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for children under 2 years; not recommended for child 2 - 10 years
09.04.02 Jevity® Plus 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Pt requires 1.2kcal/mL, fibre, vegetarian feed fish oil free
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for child under 2 years; not recommended for child 2 - 10 years
09.04.02 Jevity® Plus HP 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Pt requires 1.3kcal/mL, high protein, fibre, vegetarian feed fish oil free
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula; also CAPD, heamodialysis. Not suitable for child under 2 years; not recommended for child 2 - 10 years
09.04.02 Jevity® Promote 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Pt requires 1 kcal/mL, fibre, vegetarian feed fish oil free
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for child under 2 years; not recommended for child 2 - 10 years
09.05.02.01 Joules phosphate solution  Paediatrics only
19.37 K-BAND®  Lightweight conforming bandages are used for dressing retention, with the aim of keeping the dressing close to the wound without inhibiting movement or restricting blood flow.
A5.03.04 Kendall® AMD  Specialist use only for pin sites
Absorbent, non adherent foam disc impregnated with PHMB. Double sided with a centre hole and radial slit
Type of wound product is suitable for
For use on pin sites, drains and tubes.
Duration dressing remains on wound before changing
1-7 days
Frequency of dressing change
1-7 days dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not intended as a primary treatment for infection
Do not use as a primary treatment for full thickness burns
Not for patients sensitive to PHMB
Rationale for inclusion in formulary
Provides local exudate management and antimicrobial properties
Absorbent
Non adherent and semi occlusive
A5.17 Kerlix  Specialist recommendation only
Gauze roll containing 0.2% Polyhexamethylene Biguanide (PHMB)
Type of wound product is suitable for
Colonised or infected wounds, with moderate to heavy exudate
Duration dressing remains on wound before changing
3 days
Frequency of dressing change
3 days
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to PHMB
Do not use with Sodium hypochlorite ( Eusol) solutions, as this will deactivate PHM Do not apply gauze circumferentially as it has no stretch, and can become tight restricting circulation
Rationale for inclusion in formulary
Broad-spectrum antimicrobial agent that reduces bacterial colonization within the dressing and bacterial penetration through the dressing.
Can be used in conjunction with Renasys Negative Pressure Therapy
13.08.02 Keromask® 
  • Specialist recommendation
  • FP10 prescriptions should be endorsed "ACBS"
19.06 KerraMax Care®  HOSPITAL USE ONLY
Superabsorbent dressing
Type of wound product is suitable for
Highly exuding wounds as a primary or secondary dressing. Can be used under compression therapy
Stackable as no backing present to hold exudate
Duration dressing remains on wound before changing
1-7 days.
Frequency of dressing change
Dependent on level of exudate, usually daily or more frequently
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not cut or tear
Rationale for inclusion in formulary
Required for heavily exuding wounds.
A5.01.02 KerraMax Care®  HOSPITAL USE ONLY
Superabsorbent dressing
Type of wound product is suitable for
Highly exuding wounds as a primary or secondary dressing. Can be used under compression therapy
Stackable as no backing present to hold exudate
Duration dressing remains on wound before changing
1-7 days.
Frequency of dressing change
Dependent on level of exudate, usually daily or more frequently
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not cut or tear
Rationale for inclusion in formulary
Required for heavily exuding wounds.
A5.16 Kerraped 

First consider clients own footwear options

Preferred local option


A shoe to accommodate bandages and offload pressure from the front of the foot
Type of wound product is suitable for
Neuropathic foot ulcers or patients with bulky bandages who cannot wear their own footwear
Duration product remains on wound before changing
As required
Frequency of use
As required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.
Ensure correct size is selected
Rationale for inclusion in formulary
Only footwear available for patients with neuropathic ulcers or bulky bandages

A5.16 KerraPro® 

Preferred local option

Silicone pads designed to redistribute pressure from bony prominences.
Type of wound product is suitable for
Prevention and treatment of category (Stage/Grade) 1 pressure ulcers
Duration dressing remains on wound before changing
As required. Check skin daily.
Frequency of dressing change
As required, check skin daily. Pads will last up to 3 months
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Must only be used as part of a pressure ulcer prevention programme
Not to be used on a grade 2, 3 4, unstageable or deep tissue injury pressure ulcer unless directed by a clinical specialist
Known sensitivity to silicone
Do not use as a wound dressing
Do not apply directly onto broken skin
If skin macerates beneath, ensure the area is being checked and washed daily and consider utilising a cotton stockinette to reduce humidity
Rationale for inclusion in formulary
Cost effective
Available in a large range of shapes and sizes
Accessible pressure ulcer prevention medical device
Reusable on the same patient for up to 3 months by washing with soap and water and thoroughly drying

15.01.01 Ketamine (preservative free) 

HOSPITAL ONLY

15.01.01 Ketamine injection Ketalar®

HOSPITAL ONLY

09.04 Ketocal® 2.5:1 LQ 
  • The only complete tube feed which meets requirements for the older age group beyond 8 years of age
  • Nutritionally complete
09.04 KetoCal® 3:1 
  • Specialised formulas for specific clinical conditions
  • High fat, low carbohydrate, nutritionally complete formula for infants and children from birth to 6 yrs, or as a supplementary feed for children over 6 years and adults on a ketogenic diet. May also be used in cooking
  • Enteral feed or nutritional supplement as part of ketogenic diet in management of drug resistant epilepsy or other conditions for which a ketogenic diet is indicated in children from birth to 6 years; as a nutritional supplement in children over 6 years
09.04 KetoCal® 4:1 
  • Specialised formulas for specific clinical conditions
  • High fat, low carbohydrate powdered formula for children on a ketogenic diet as oral or tube feed, or used in cooking or as a supplementary feed for adults on a ketogenic diet
  • Enteral feed or nutritional supplement as part of ketogenic diet in management of epilepsy resistant to drug therapy, in children over 1 year, only on the advice of secondary care physician with experience of ketogenic diet
09.04 KetoCal® 4:1 LQ 
  • Specialised formulas for specific clinical conditions
  • High fat, low carbohydrate nutritionally complete liquid for children over 1 year of age and adults on a ketogenic diet, suitable for oral or tube feeding
  • Enteral feed or nutritional supplement as part of ketogenic diet in management of drug resistant epilepsy or other conditions for which a ketogenic diet is indicated in children 1–10 years; as a nutritional supplement in children over 10 years
05.02.02 Ketoconazole 

Specialist use only

06.07 Ketoconazole 
13.10.02 Ketoconazole 2% cream 
13.09 Ketoconazole 2% shampoo 

Over the counter preparation suitable for self-care/purchase if appropriate

06.01.06 Ketones Test Strips FreeStyle Optium beta-ketone testing strips®
  • FreeStyle Optium beta-ketone testing strips
06.01.06 Ketones Test Strips KetoSens testing strips ®
  • KetoSens testing strips
06.01.06 Ketones Test Strips Glucofix Tech beta-ketone Sensor testing strips ®
11.08.02 Ketorolac Acular®

For use on advice of specialist

21 Ketorolac  
15.01.04.02 Ketorolac trometamol Toradol®

Hospital only

09.04 KeyOmega® 
  • Long chain fatty acid supplementation in very low fat diets
  • Nutritional supplement for the dietary management of inborn errors of metabolism
19.47 K-FOUR ® Compression Bandaging Kit  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details.

Prescribe as individual items and quantities NOT as a ‘kit’. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective.

The ‘gold standard’ for immobile/poor mobility patients to achieve healing by graduated compression.
19.11 Kliniderm®  •November 2016: approved for use, replacing Mepilex®
Polyurethane foam with adhesive silicone wound contact layer
Type of wound product is suitable for
Suitable for acute and chronic wounds including leg ulcers, pressure ulcers, superficial and partial thickness burns, donor sites, post operative wounds and skin abrasions. Suitable for low to moderately exuding wounds for patients with fragile skin
Available in border and non border
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
1-7 days – dependant on exudate level
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity eg Silicone
Rationale for inclusion in formulary
Wound contact surface is coated with a layer of soft silicone which reduces trauma to delicate tissue. Range of shapes and sizes available.
A5.02.03 Kliniderm® 

November 2016: approved for use, replacing Mepilex®

Polyurethane foam with adhesive silicone wound contact layer

Type of wound product is suitable for
Suitable for acute and chronic wounds including leg ulcers, pressure ulcers, superficial and partial thickness burns, donor sites, post operative wounds and skin abrasions. Suitable for low to moderately exuding wounds for patients with fragile skin
Available in border and non border

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days – dependant on exudate level

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity eg Silicone

Rationale for inclusion in formulary
Wound contact surface is coated with a layer of soft silicone which reduces trauma to delicate tissue. Range of shapes and sizes available.

06.04.01.01 Kliofem® 
06.04.01.01 Kliovance® 
A5.08.04 K-Lite 

Preferred local option

Lightweight knitted bandage

Type of wound product is suitable for
Designed for use on sprains/strains
Can be used to prevent oedema, would require a wadding bandage to be applied
beneath
It is the second layer of a four layer compression bandage kit
Where there is open skin, a primary dressing must be used

Duration dressing remains on wound before changing
Change in line with primary dressing

Frequency of dressing change
1-7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known allergy to any components
Not suitable for application of pressure on its own and therefore should be used with other bandage components for the treatment of venous ulcers
Caution over bony prominences where the bandage can cause pressure

Rationale for inclusion in formulary
Cost effective
Essential for providing support to a limb and as part of a bandage compression therapy kit

19.41 K-LITE®  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details.

Prescribe as individual items and quantities NOT as a ‘kit’. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective.

The ‘gold standard’ for immobile/poor mobility patients to achieve healing by graduated compression.
A5.08.02 Knit-Band 

Preferred local option

Cellulose contour bandage used for retention of non adhesive dressing products
Type of wound product is suitable for
Retention bandage
Duration dressing remains on wound before changing
Change in line with dressing change
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Take care to apply joint below to joint above. Always use a primary dressing
Rationale for inclusion in formulary
Most cost effective choice

19.47 KO-FLEX® Compression Bandage Class 3b Cohesive Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details.

Prescribe as individual items and quantities NOT as a ‘kit’. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective.

The ‘gold standard’ for immobile/poor mobility patients to achieve healing by graduated compression.
A5.08.06 Ko-Flex® 

Preferred local option

A water resistant vapour permeable cohesive bandage
Type of wound product is suitable for
Venous ulceration, oedema, Managing sprains and strains and following orthopaedic
surgery
Forms part of the K four bandage system
Duration dressing remains on wound before changing
1 to 7 days
Frequency of dressing change
Dependant on exudate levels if wound present or oedema management .
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.
Not recommended on those patients with an ABPI lower than 0.8.
Contains latex
Rationale for inclusion in formulary
Cohesive bandage that can be used alongside other formulary products
Forms the 4th layer of a four layer compression bandage system

19.41 K-PLUS®  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details.

Prescribe as individual items and quantities NOT as a ‘kit’. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective.

The ‘gold standard’ for immobile/poor mobility patients to achieve healing by graduated compression.
A5.08.07 K-Soft 

Preferred local option

An absorbent non –woven, sub bandage wadding.
Type of wound product is suitable for
Provides padding , shaping and protection of the limb prior to the application of
compression bandage therapy.
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
Daily up to weekly dependant on exudate and oedema management.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Advised not to apply directly to skin as can cause irritation.
Rationale for inclusion in formulary
Essential for protecting a limb, padding and shaping
Forms part of the compression bandage regime. Suitable for use with other formulary products.

19.46 K-SOFT® Absorbent Wadding
19.47 K-THREE ®  Indications: venous leg ulceration. Doppler assessment (ABPI) and/or specialist assessment are required before use. Only to be applied by trained individuals – refer to manufacturer’s application guidelines for details.

Prescribe as individual items and quantities NOT as a ‘kit’. System used is dependent upon ankle circumference which should be re-measured at each dressing change to ensure that the system used is still safe and effective.

The ‘gold standard’ for immobile/poor mobility patients to achieve healing by graduated compression.
A5.03.04 KytoCel 

Preferred local option

Absorbent gelling fibre wound dressing

Type of wound product is suitable for
Moderate to heavily exuding chronic and acute wounds that are sloughy and clinically infected.
Haemostatic properties for minor bleeds in superficial wounds
Autolytic debridement properties
Duration dressing remains on wound before changing
1-3 days
Frequency of dressing change
1-3 days, dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to Shellfish (Chitin)
Full thickness burns
Heavily bleeding wounds
Dry wounds
Rationale for inclusion in formulary
Cost effective
Alternative to available antimicrobials
Can be used on heavily exuding wounds

02.04 Labetalol 
02.04 Labetolol 
04.08.01 Lacosamide 

Tablets

Syrup

Supported by an ESCA

01.06 Lactulose 
05.03.01 Lamivudine Epivir®, Zeffix®
05.03.01 Lamivudine 
05.03.01 Lamivudine with dolutegravir Dovato®
05.03.01 Lamivudine with tenofovir disoproxil and doravirine Delstrigo®
04.02.03 Lamotrigine 

On specialist advice.

04.08.01 Lamotrigine 

Tablets

Dispersible tablets

On specialist advice

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particular manufacturer's product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

03.04.03 Lanadelumab Takhzyro®

In line with NICE

Highly specialist allergy centre- NHSE commissioned

08.03.04.03 Lanreotide Somatuline® LA

NHSE: Commissioned in cancer; product with lowest procurement cost to be used


 Palliative Care use only

Red Traffic Light  For Oncology 

Red Traffic Light  For Acromegaly 

08.03.04.03 Lanreotide Somatuline Autogel®

NHSE: Commissioned in cancer; product with lowest procurement cost to be used


   Palliative Care Use Only

Red Traffic Light  For Oncology 

Red Traffic Light  For Acromegaly

01.03.05 Lansoprazole 

Capsules are more cost effective than tablets

Can be opened and beads swallowed without crushing or can be mixed with food or drink

01.03.05 Lansoprazole 

Capsules are more cost effective than tablets

Can be opened and beads swallowed without crushing or can be mixed with food or drink

 

unlicensed dfsdfsdfsdfdsdf

01.03.05 Lansoprazole dispersible 

Orodispersible tablets 15mg, 30mg
Orodispersible tablets cost twice as much as capsules

For use in patients with swallowing difficulties or who are on enteral tube feeding

 

09.05.02.02 Lanthanum 
  • Specialist recommendation
  • No ESCA
  • Common Practice

NHSE commissioned when used for renal dialysis in most circumstances

08.01.05 Lapatinib Tyverb®

Not routinely commissioned by NHSE

09.08.01 L-arginine   Dot tablets
Dot oral solution
Dot infusion 100ml
Dot capsules
08.01.05 Larotrectinib Vitrakvi®

In line with NICE

A5.10 LarvE 

Specialist recommendation only
Free range: Biomonde Larvae 100/200 or BioBag
Biosurgical treatment for the debridement and cleansing of wounds consisting of aseptically produced living larvae.
The BioBag is presented in the five (5) configurations listed below. The larvae are Lucilia sericata contained in a sterile polyester net bag with a sterile PVA spacer cube, presented in a sterile transport container.
BioBag 50 at least 50 larvae 25 x 40mm 1 8x8x10
BioBag 100 at least 100 larvae 50 x 40mm 1 12x12x10
BioBag 200 at least 200 larvae 60 x 50mm 1 25x10x10
BioBag 300 at least 300 larvae 120 x 60mm 2 25x10x10
BioBag 400 at least 400 larvae 100 x 100mm 2 25x10x10
Free range larvae, larvae and 30 x 30 flat retention net plus kit pack, larvae and 40 x
60cm boot retention net plus kit pack. Additional 100 or 200 larvae available.
Type of wound product is suitable for
The BioMonde Larval Debridement Therapy Products are indicated for debridement of non-healing necrotic skin and soft tissue wounds, including pressure ulcers, venous stasis ulcers, neuropathic foot ulcers, and non-healing traumatic or post-surgical wounds.
Duration dressing remains on wound before changing and frequency of dressing change
An application of BioBag can be left in place for up to 4 days, dependent on the
condition of the wound. If the wound is not sufficiently debrided after 4 days, the treatment can be repeated with a fresh application of BioBag. The treatment should be stopped as soon as the wound is sufficiently debrided or if no improvement is observed after 3 or more applications. The total number of treatment cycles will depend on the characteristics of the wound, the response of the patient to LDT and the aim of the therapy. Most ulcers are completely debrided within 1 to 6 treatment cycles. If exudate production is excessive, the secondary dressing may be changed as required while leaving the BioBag undisturbed. Frequent removal of the outer dressing will also help to control the odour associated with the liquefied necrotic tissue
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Larvae should not be used in patients with known hypersensitivities to fly larvae, polyester, PVA (polyvinyl alcohol) or the components of the media on which the larvae are raised (including soya protein, yeast protein, potato starch and bovine protein) as this may result in dermatitis or more severe immunological reactions in susceptible individuals. If treatment is undertaken then these patients should be under strict medical supervision for the duration of the treatment with immediate access to care. Patients with life or limb-threatening, rapidly advancing infections should not be
treated with as LDT may interfere with the close and frequent observation that these
patients require.
Should not be used as first line therapy of infected tendon and bone. These wounds
should be treated surgically and/or with antibiotics before using LDT.
Should not be used to treat wounds which are not directly exposed to the outside.
Wounds should never be allowed to close over the larvae either intentionally or unintentionally.
Should not be used on wounds with an inadequate blood supply as this ultimately reduces the ability of the wound to heal. LDT will enlarge the wound as necrotic tissue is debrided but the resulting clean wound is at risk from re-infection.
Although some mild bleeding is common during LDT, larvae should not be used on wounds that have a tendency to bleed or wounds close to an exposed major blood vessel, especially if considered to be necrotic as this can lead to rupture of the blood vessels which could be life-threatening. If LDT is attempted, the patient must remain under strict medical supervision for the duration of the treatment.
Should not be used on patients with an inborn or medication-induced coagulopathy or
in patients being treated with anticoagulants. If these patients are treated with LDT, they should remain under strict medical supervision for the duration of the treatment. Should never be used in sterile body cavities.
Should be used with caution on wounds over adjacent exposed organs or leading to a body cavity, and only under close medical supervision for the duration of the treatment. Data are not available concerning the antibiotic / antiseptic activity of maggots and therefore any infected wound should receive standard antibiotic care.
Rationale for inclusion in formulary
Only available larval therapy on prescription.
Rapid debridement of chronic wounds
Can be utilised in the community

11.06 Latanoprost 

Ist line

On Specialist Ophthalmologist Recommendation

11.06 Latanoprost Monopost ®

1st Line PF option

On Specialist Ophthalmologist Recommendation

11.06 Latanoprost 0.005% with Timolol 0.5% 

On Specialist Ophthalmologist Recommendation

11.06 Latanoprost with Timolol preservative free Fixapost®

Specialist Ophthalmologist Recommendation

09.08.01 L-carnitine  NHSE commissioned
Dot liquid-specialist advice only
Dot injection
09.08.01 L-citrulline 
05.03.03.02 Ledipasvir/sofosbuvir Harvoni®

 

In line with NICE

10.01.03 Leflunomide 

Supported by an ESCA

08.02.04 Lenalidomide 

In line wth NICE

09.01.06 Lenograstim  Hospital only
08.01.05 Lenvatinib Kisplyx®

In line with NICE

02.08 Lepirudin 
02.06.02 Lercanidipine 
  •  Tablets
05.03.02.02 Letermovir Prevymis®

In line with NICE

08.03.04.01 Letrozole 
06.07.02 Leuprorelin Prostap 3 DCS®
06.07.02 Leuprorelin Prostap SR DCS®
06.07 LEUPRORELIN ACETATE 

Amber Initiation - Prostap 3 DCS

Amber Initiation - Prostap SR DCS

08.03.04.02 Leuprorelin Acetate Prostap® SR

Advanced prostate cancer

08.03.04.02 Leuprorelin Acetate Prostap® 3

Advanced prostate cancer

05.05 Levamisole 

Unlicensed

05.05 Levamisole > Ergamisol 
04.08.01 Levetiracetam Desitrend®

Paediatrician initiation

For patients up to and including 16 years of age who are unable to swallow tablets and in whom the liquid formulation is not appropriate or tolerated

MHRA Advice
It is usually unnecessary to ensure that patients are maintained on a specific maufacturer's product unless there are specific reasons such as patient anxiety and risk of confusion or dosing errors

04.08.01 Levetiracetam 

Tablets

SF oral solution

Coated granules in sachets (see Desitrend®)

On specialist advice

MHRA Advice
It is usually unnecessary to ensure that patients are maintained on a specific manufacturer's product unless there are specific reasons such as patient anxiety and riak of confusion or dosing errors

15.02 Levobupivacaine Chirocaine®

Hospital only

15.02 Levobupivacaine 0.1% with Fentanyl 2mcg/ml 

Hospital only

15.02 Levobupivacaine 0.1% with Fentanyl 4mcg/ml 

Hospital only

05.01.12 Levofloxacin 
  • For multi resistant organisms, based on Microbiological sensitivity
05.01.12 Levofloxacin 
11.03.01 Levofloxacin Oftaquix®

2nd line

Use SDU if using 1 or 2 hourly or if significant OSD/toxicity

For use by consultant ophthalmologists in patients undergoing surgical procedures who are allergic to chloramphenicol or in patients undergoing intravitreal injections who are allergic to chloramphenicol and allergic to/intolerant of preservatives

More cost effective option available

04.02.01 Levomepromazine 

Supported by ESCA

04.02.01 Levomepromazine 

Not to be used for psychiatric / anxiolytic purposes in Primary Care

04.06 Levomepromazine 

For palliative care only

07.03.05 Levonorgestrel Levonelle® 1500

Less effective than insertion of IUD.

Effective up to 72 hours post-coitus

Effectiveness of EHC reduced in women taking enzyme inducing drugs, IUD preferred option, see MHRA link below regarding dose adjustment.

Use barrier contraception until next period.

Available free of charge via some community pharmacies

07.03.02.01 Levonorgestrel 30mcg Norgeston®
06.02.01 Levothyroxine 
15.01 Lidocaine  Versatis® For use in neuropathic pain on advice of pain clinic only
RICaD required for prescribing in primary care.
15.02 Lidocaine 
12.03.01 Lidocaine 10%  

Hospital only

15.02 Lidocaine 10% 

Hospital only

15.02 Lidocaine 2% adrenaline 1:200,000 
15.02 Lidocaine 2% adrenaline 1:80,000 
15.02 Lidocaine 2% with Chlorhexidine 0.25% Instillagel®
15.02 Lidocaine 2.5% with Prilocaine 2.5% EMLA®
15.02 Lidocaine 4% laryngojet®

Hospital only 

Dental use under review

15.02 Lidocaine 4% LMX®

For paediatric use only

15.02 Lidocaine 5% 
15.02 Lidocaine 5% and Phenylephrine 0.5% 

Hospital only

04.07.03 Lidocaine 5% patch Versatis®

Approved only in patients who have been treated in line with NICE CG173: Neuropathic pain in adults: pharmacological management in non-specialist settings  but are still experiencing neuropathic pain associated with previous hepes zoster infection (post-herpetic neuralgia)

Following the policy - Items which should not routinely be prescribed in Primary Care. There is an exception for lidocaine for treatment of neuropathic pain in adults.

02.03.02 Lidocaine hydrochloride 
15.02 Lidocaine with Adrenaline Lignospan®
15.02 Lidocaine with Adrenaline Xylocaine®
15.02 Lidocaine with tetracaine Pliaglis®

Hospital only

15.02 Lidocaine, adrenaline & tetracaine LAT®

Hospital only

15.02 Lignocaine 

Hospital only

A5.11 LimbO Waterproof Protector 

Waterproof protector, non slip latex free with a flexible seal at the opening
Type of wound product is suitable for
Used to keep arm, PICC, leg and foot dressings dry, can be fully submerged in water
Rationale for inclusion in formulary
Multiple sizing for legs and arms

01.06.07 Linaclotide Constella®

For moderate to severe IBS-Constipation

For patients who have not responded adequately to or cannot tolerate all other suitable treatment options BUT BEFORE other agents with higher costs

Supported by a RICaD (in development)

06.01.02.03 Linagliptin 

In line with NICE
Linagliptin has no significant clinical benefit or renoprotective effect in patients with CKD.

Sitagliptin should be used first line at the appropriate renal dose
where a DPP4 inhibitor is indicated


No significant clinical benefit when used in combination
with Insulin – avoid using together

06.01.02.03 Linagliptin/ Metformin Jentadueto ®

A variety of combinations tablets (dual therapies)
of oral diabetes medication can be prescribed and
are available in the Drug Tariff.


Overall, they may improve compliance in patients,
however some combinations would then not allow
the flexibility in dosing that is required for diabetes
management and in some cases increase the
tablet burden. There are specific sick-day rules
related to stopping certain medication which
would be further complicated where they are not
prescribed in their separate formulations.


Furthermore, for the overall health economy not
all combination therapies are cost-effective and
this will be increasingly so as the patents expire
over the near future. There are some combination
therapies that are not recommended in the oral
guidance and clinicians are guided to review and
discuss these with patients as part of shared -care
decision making.


There are complexities also around the lack of
licensing of dual therapies in specific cohorts of
patients, related to prescribing for the indication of
heart failure or renal disease, making this a
complex area for prescribing in primary care

05.01.07 Linezolid 

For hospital use only

05.01.07 Linezolid 

For hospital use only

06.02.01 Liothyronine 
06.02.01 Liothyronine 
20 Lipiodol 

For andoscopy use only

09.04 Lipistart® (Vitaflo) 
  • Specialised formulas: Infant and child: MCT-enhanced formula
  • Essential for infants/children with long chain fatty acid oxidation disorders who need a high intake of MCT but require normal proportions of carbohydrate e.g. CPT1 and CPT2 deficiency. High carbohydrate formulas are unnecessary
  • Also essential for infants/children with long chain fatty acid oxidation disorders who need a high intake of MCT but require normal proportions of carbohydrate e.g. CPT1 deficiency (i.e. high carbohydrate formulas may be unnecessary). There should always be 2 powdered high MCT formulae in the formulary in case of supply issues. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Dietary management of fat malabsorption, long-chain fatty acid oxidation disorders, and other disorders requiring a high MCT, low LCT formula
13.02.01 Liquid and White Soft Paraffin Ointment (50:50) 

Most greasy option

Over the counter preparation suitable for self-care/purchase if appropriate

A5.13 Liquid paraffin/white soft paraffin 50:50 

Preferred local option

Emollient ointment containing liquid paraffin and white soft paraffin
To assist the skin in retaining moisture
Type of wound product is suitable for
For use on all dry skin conditions including eczema and psoriasis
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Treatment of dry skin conditions.
Dermatology approved

09.04 Liquigen® 
  • High-energy supplements: fat
  • Used as a source of MCT when required for children and adults with LCT intolerance and on a low LCT diet and for adults and children on a ketogenic diet - ££
  • Also this is used as a milk replacement and as part of module tube feeds for patients with long chain fatty acid disorders such as LCHADD and VLCADD who require ≥10% fat calories from long chain fat and a diet supplemented with MCT. It is essential to provide essential energy on fat restricted diets if MCT is tolerated by the patient. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Steatorrhoea associated with cystic fibrosis of the pancreas, intestinal lymphangiectasia, intestinal surgery, chronic liver disease, liver cirrhosis, other proven malabsorption syndromes, ketogenic diet in epilepsy, and in type 1 lipoproteinaemia
  • Not suitable for child under 1 year
06.01.02.03 Liraglutide Saxenda®

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

• Injection
• For weight loss/ obesity
• Use according to NICE guidance

The use of Liraglutide for this indication is restricted to prescribing in secondary care by a specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Saxenda ®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes

 

06.01.02.03 Liraglutide Victoza®

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

Use according to NICE guidance

For the treatment of type 2 diabetes ONLY

THIS IS FOR DIABETES ONLY.  Prescribe by brand (Victoza®) to avoid patients inadvertently receiving a different product licensed for obesity.

04.04 Lisdexamphetamine Elvanse®

Please note that commissioning discussion is underway. However the present status is as follows:-

Amber SC Age 6 and over - Solihull practices.  Supported with ESCA


Amber SC Age 16 and over - Birmingham practices.  Supported with ESCA


Red Age under 16 - Birmingham practices


Amber SC Age 6 and over - Sandwell and West Birmingham CCG.  Supported with ESCA

 

02.05.05.01 Lisinopril 
06.01.05 Lisinopril 
04.02.03 Lithium Carbonate  
  • Supported by ESCA-requires regular review in secondary care. Full discharge at 12 months
  • APC preferred brand is Priadel, however there are other brands available and you should continue to prescribe the brand that the patient is stable on
  • Below is an ESCA link for patients seen by the Black Country Mental Health Services 
04.02.03 Lithium Citrate 
  • Supported by an ESCA-requires regular review in secondary care. Full discharge at 12 months
  • APC preferred brand is Priadel, however there are other brands available and you should continue to prescribe the brand that the patient is stable on
  • Below is an ESCA link for patients seen by the Black Country Mental Health Services
06.01.02.03 Lixisenatide 
A5.03.01 L-Mesitran® 

UHB specialists only
A hydro active gel dressing containing medical grade honey available without or with an adhesive film border. L- Mesitran has anti bacterial properties and can debride and reduce malodour.
Type of wound product is suitable for
Burns, chronic wounds, necrotic/sloughy wounds, surgical wounds, diabetic ulcers with caution, donor sites, fungating wounds.
Max Duration dressing remains on wound before changing
3-7 days
Frequency of dressing change
3- 7 days, dependent on exudate level
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to dressing and any of its components use with caution in patients with bee venom allergy
Not suitable for full thickness burns/deep narrow cavities
Caution must be exercised when applying to diabetic patients. Blood glucose levels must be monitored.
Rationale for inclusion in formulary
Desloughing, Antimicrobial, Deodorising

09.04 Locasol® 
  • Specialised formulas: Infant and child: Low calcium formula
  • Use in children with high blood calcium levels eg. Noonan’s syndrome
  • Conditions of calcium intolerance requiring restriction of calcium and vitamin D intake
04.03.01 Lofepramine 
04.10.03 Lofexidine BritLofex®
08.01.01 Lomustine 

Commissioned by NHSE

01.04.02 Loperamide 

Capsules are more cost effective than tablets

Loperamide melts (orodispersible) tablets are reserved for high risk stoma output patients  and patients with swallowing difficulty only

Not to be used if C.diff is suspected

Caution in patients with a history of recent or repeated antibiotic use as increased risk of C.diff infection in this group

01.04.02 Loperamide with simeticone 
09.04 Lophlex® 
  • A supplement without phenylalanine for teenagers and adults with phenylketonuria
  • One of 2 powdered amino acid supplement without phenylalanine for teenagers and adults with phenylketonuria that will meet their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-phenylalanine protein requirements. It is important we have a choice of more than 1 product for this age group as compliance is reported to be poor and the potential outcome of poor compliance is poor executive functioning. The 2 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of proven phenylketonuria in children over 8 years and adults including pregnant women
05.03.01 Lopinavir and Ritonavir Kaletra®
05.03.01 Lopinavir with Ritonavir 
09.04 Loprofin SnoPro® 
  • Specialised formulas for specific clinical conditions
  • Low protein, low potassium, low Phosphate milk substitute , used as a milk replacement in children with renal disease and IMD
  • Nutritional supplement for the dietary management of phenylketonuria, chronic renal failure and other inborn errors of amino acid metabolism
09.04 Loprofin® PKU Drink 
  • Low protein milk for children and adults with phenylketonuria and other disorders of protein metabolism
  • Low energy protein milk for children and adults with phenylketonuria and other disorders of protein metabolism who are overweight
  • Nutritional supplement for the dietary management of phenylketonuria in children over 1 year and adults
09.04 Loprofin® Sno-Pro 
  • Low protein milk for children and adults with phenylketonuria and other disorders of protein metabolism
  • High energy low protein milk for children and adults with phenylketonuria and other disorders of protein metabolism who are underweight. Unsuitable for MSUD
  • Nutritional supplement for the dietary management of phenylketonuria, chronic renal failure and other inborn errors of amino acid metabolism
03.04.01 Loratadine 

OTC preparation suitable for self-care/purchase if appropriate

04.01.02 Lorazepam 
04.01.02 Lorazepam 
15.01.04.01 Lorazepam 

Hospital only

21 Lorazepam  
  • For breathlessness where anxiety is predominant feature
  • Genus brand for sublingual use (blue tablets)
09.04 Lorenzo’s oil 
  • For dietary treatment of adrenoleukodystrophy. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
08.01.05 Lorlatinib Lorviqua®

In line with NICE

09.08.01 L-ornithine L-aspartate 
02.05.05.02 Losartan 
06.01.02.03 Losartan Potassium 
11.04.01 Loteprednol Lotemax®
09.04 Low fat +1 module 
  • Specialised formulas: Infant and child: MCT-enhanced formula
  • Children and adults with a fatty acid disorder
  • Also fat free preparation. Used by patients with long chain fatty acid oxidation disorders who cannot tolerate MCT and require a very low-fat diet. Suitable for children and adults with a fatty acid disorder. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
03.01.05 Low range peak flow meter 

 BRANDS

  • Rossmax Peak Flow Meter
  • Easy Peak Flow Meter Low Range
06.04.01.01 Lubion® 

Fertility use only

20 Lugol’s iodine for assessment of squamous dysplasis/cancer 

For use by endoscopy speciality at Sandwell and West Birmingham NHS Trust

03.07 Lumacaftor with ivacaftor Orkambi®

In line with NICE

03.13 Lumacaftor with ivacaftor Orkambi®
03.14 Lumacaftor with Ivacaftor Orkambi®
09.01.04 Lusutrombopag Mulpleo®

Use in line with NICE

08.03.04.03 Lutetium (177Lu) oxodotreotide Lutathera®

Hospital use only

In line with NICE

05.01.03 Lymecycline oral presentations
13.06.02 Lymecycline 
  • Topical treatments should be used first line.
  • Oral antibiotics should be reserved for acne, if topical treatment is not adequately effective or if it is inappropriate.
A5.09.02 Lymphoedema garments 

Based on assessment

02.05 Macitentan Opsumit®

NHS England commissioned

01.06 Macrogol 3350 with anhydrous sodium sulfate, ascorbic acid, potassium chloride, sodium ascorbate and sodium chloride 
01.06 Macrogol 3350 with anhydrous sodium sulfate, potassium chloride, sodium bicarbonate and sodium chloride 
01.06 Macrogol 3350 with potassium chloride, sodium bicarbonate and sodium chloride  
01.06.04 Macrogols  Laxido®

Follow Optimise Rx recommendation on the most cost effective brand to prescribe

Prescribe as Laxido

01.06.05 Macrogols Klean-Prep®
01.06.05 Macrogols Moviprep®
11.08.01 Macrogols  Systane®

Non-formulary
For existing patients only

09.05.01.03 Magnaspartate® 
09.05.01.03 Magnesium citrate 
01.06 Magnesium citrate with sodium picosulfate 
09.05.01.03 Magnesium glycerophosphate 
09.05.01.03 Magnesium Sulphate Injection  For use in hospital only
13.10.05 Magnesium Sulphate Paste  

Over the counter preparation suitable for self-care/purchase if appropriate

01.01.01 Magnesium Trisilicate Mixture BP 

Suspension

High sodium content

Use with caution in patients with renal impairment

03.13 Magnessium sulfate 

Severe acute asthma,Continuing respiratory deterioration in anaphylaxis

A5.11 Magnide 

Preferred local option

Application of closed toe compression garments

13.10.04 Malathion  

Over the counter preparation suitable for self-care/purchase if appropriate

02.02.05 Mannitol 

Hospital use only

03.07 Mannitol  Bronchitol®

Hospital only
Commissioned by NHSE

03.07 Mannitol inhalation Bronchitol ®
05.03.01 Maraviroc 
05.03.01 Maraviroc Celsentri®
09.04 Maxijul® Super Soluble 
  • High-energy supplements: carbohydrate
  • High calorie modular powder, to be added to other food, drink and feeds e.g. faltering growth, to increase carbohydrate content
  • Also used as an additional energy supplement when IMD patients require a modified, low protein or low-fat feed or are on a glucose polymer based energy supplement and require other Nutricia products such as Monogen or Nutrini fibre, so it can be delivered using the same home delivery service so less burdensome for families. It is also used as a core ingredient for glucose based emergency feeds. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high or readily available carbohydrate supplement
09.04 MCT Pepdite® +1 
  • Not used, other preparation more nutritionally complete
09.04 MCT Procal® 
  • Protein, fat, and carbohydrate
  • Used in children and adults on a ketogenic diet as an energy source for use with long chain fatty acid disorders and in metabolic disorders
  • Used in liver/hepatobiliary disease/conditions
  • Essential for use with log chain fatty acid disorders such as LCHADD, VLCADD, CACT. It provides a pre-measured source of MCT energy at breakfast, midday and evening to ensure patients do not become energy depleted when performing usual daytime activities. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Dietary management of disorders of long-chain fatty acid oxidation, fat malabsorption, and other disorders requiring a low LCT, high MCT supplement
  • Not suitable for child under 1 year
14.04 Measles, Mumps and Rubella Vaccine, Live (MMR) Priorix ® MMRVaxPRO®
05.05 Mebendazole 

Also available to buy OTC

05.05 Mebendazole > Vermox 
01.02 Mebeverine Hydrochloride 
19.20 MEDIHONEY ® Antibacterial Honey Apinate Non adherent calcium alginate dressing impregnated with medical grade honey Indications: sloughy, necrotic or granulating wounds. Honey has an osmotic effect that helps deslough wounds and maintain a moist environment. Antibacterial activity against common wound pathogens, including MRSA.

Can be left on for up to 7 days dependent upon exudate. Deodorises the wound as bacteria adhere to sugar present. Exudate levels may increase and pain may be experienced owing to the osmotic action. Use a barrier cream to protect wound edges. Wound may appear larger and deeper initially as dead tissue is removed but an improvement in appearance should follow.

SAFE to use on diabetic patients just monitor blood sugars. Do NOT use if sensitive to honey or bees.
19.20 MEDIHONEY ® Antibacterial Medical Honey 20g and 50g tube Apply 3mm deep only Indications: sloughy, necrotic or granulating wounds. Honey has an osmotic effect that helps deslough wounds and maintain a moist environment. Antibacterial activity against common wound pathogens, including MRSA.

Can be left on for up to 7 days dependent upon exudate. Deodorises the wound as bacteria adhere to sugar present. Exudate levels may increase and pain may be experienced owing to the osmotic action. Use a barrier cream to protect wound edges. Wound may appear larger and deeper initially as dead tissue is removed but an improvement in appearance should follow.

SAFE to use on diabetic patients just monitor blood sugars. Do NOT use if sensitive to honey or bees.

Medical grade honey is applied directly to the wound and covered with primary low adherence wound dressing; as additional secondary dressing may be required for exuding wounds
19.20 MEDIHONEY ® Antibacterial Wound Gel 80% antibacterial medical honey + natural waxes / oils to form gel Indications: sloughy, necrotic or granulating wounds. Honey has an osmotic effect that helps deslough wounds and maintain a moist environment. Antibacterial activity against common wound pathogens, including MRSA.

Can be left on for up to 7 days dependent upon exudate. Deodorises the wound as bacteria adhere to sugar present. Exudate levels may increase and pain may be experienced owing to the osmotic action. Use a barrier cream to protect wound edges. Wound may appear larger and deeper initially as dead tissue is removed but an improvement in appearance should follow.

SAFE to use on diabetic patients just monitor blood sugars. Do NOT use if sensitive to honey or bees.
Not recommended for deep wounds or cavities where removal of waxes may be difficult
19.20 MEDIHONEY ® Gel Sheet Sodium Alginate dressing impregnanted with medihoney Indications: sloughy, necrotic or granulating wounds. Honey has an osmotic effect that helps deslough wounds and maintain a moist environment. Antibacterial activity against common wound pathogens, including MRSA.

Can be left on for up to 7 days dependent upon exudate. Deodorises the wound as bacteria adhere to sugar present. Exudate levels may increase and pain may be experienced owing to the osmotic action. Use a barrier cream to protect wound edges. Wound may appear larger and deeper initially as dead tissue is removed but an improvement in appearance should follow.

SAFE to use on diabetic patients just monitor blood sugars. Do NOT use if sensitive to honey or bees.
A5.15 Medihoney barrier cream 

Specialist recommendation only
Barrier cream containing active Medihoney.
Helps to reduce inflammation.
Type of wound product is suitable for
Treatment of incontinence related lesions
Blistered skin
Prevention and treatment of maceration and excoriation
Treats candidiasis and intertrigo
Duration dressing remains on wound before changing
At each episode of hygiene
Frequency of dressing change
At each episode of hygiene
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Patch test before use

Suitable for neonates and children
Treats fungal infections as well as incontinence associated lesions
Reduces inflammation
Can be applied to broken skin

09.04 Medium-chain Triglyceride (MCT) Oil 
  • High-energy supplements: fat
  • Used as a source of energy for children and adults requiring a low LCT/ High MCT diet
  • Also this is used as a MCT cooking oil to improve diet palatability in patients with long chain fatty acid disorders such as LCHADD and VLCADD who require ≥10% fat calories from long chain fat. It is used to make MCT margarine, add to toast or to cook potatoes and other vegetables. It is essential to provide essential energy on fat restricted diets if MCT is tolerated by the patient. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Nutritional supplement for steatorrhoea associated with cystic fibrosis of the pancreas, intestinal lymphangiectasia, intestinal surgery, chronic liver disease and liver cirrhosis, other proven malabsorption syndromes, ketogenic diet in management of epilepsy, type 1 hyperlipoproteinaemia
06.04.01.02 Medroxyprogesterone Acetate Depo -Provera®
06.04.01.02 Medroxyprogesterone Acetate Climanor®
06.04.01.02 Medroxyprogesterone Acetate Provera®
06.04.01.02 Medroxyprogesterone Acetate Sayana press®

Suitable for self injection in patients who have had appropriate tranining

07.03.02.02 Medroxyprogesterone acetate Sanyana Press®

Suitable for self-injection in patients who have had appropriate training

07.03.02.02 Medroxyprogesterone Acetate Depo-Provera®

Short or long term – lasts 12 weeks

In adolescents, medroxyprogesterone acetate should be used only when other methods of contraception are inappropriate;

In all women, the benefits of using medroxyprogesterone acetate beyond 2 years should be evaluated against the risks;

In women with risk factors for osteoporosis, a method of contraception other than medroxyprogesterone acetate should be considered.

08.03.02 Medroxyprogesterone Acetate 
10.01.01 Mefenamic Acid 

For dysmenorrhoea - NSAIDs significantly reduce menstrual blood loss compared with placebo. There is no significant difference between mefenamic acid and naproxen, or between NSAIDs and oral progesterone given in the luteal phase

Ibuprofen or naproxen can also be prescribed for the treatment of dysmenorrhoea

19.32 MEFIX ® Only to be used for securing dresings
A5.07.03 Mefix® 

Preferred local option

Permeable, aperture non woven, synthetic adhesive tape
For securing dressings.
Frequency of dressing change
Determined by wound type and dressing change
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None listed
Rationale for inclusion in formulary
Available on drug tariff. Different availability of sizes in comparison to Clinipore® for
difficult to dress areas. Some stretch and flexibility to improve conformity and adhesion. Can be used to secure dressings rather than bandages.

05.04 Mefloquine  
05.04 Mefloquine Lariam®

Private prescription in Primary Care

08.03.02 Megestrol Acetate 
04.01.01 Melatonin  
04.01.01 Melatonin 3mg tablets 

Amber SC REM sleep behaviour disorder and circadian rhythm sleep-wake disorder in adults in line with ESCA

 Red  For all other indications

04.01.01 Melatonin MR Circadin ®

Amber SC  Sandwell & West Birmingham CCG for patients seen by the Black Country ADHD Services.  

Amber SC REM sleep behaviour disorder and circadian rhythm sleep-wake disorder in adults in line with ESCA

 Red  For all other indications

08.01.01 Melphalan 

Commissioned by NHSE
Injection-hospital only

04.11 Memantine 
  • Tablets
09.06.06 Menadiol Sodium Phosphate 
14.04 Meningococcal A, C, W135, and Y conjugate vaccine Menveo® Nimenrix®
14.04 Meningococcal group B Vaccine Bexsero®
14.04 Meningococcal group C conjugate vaccine Menjugate Kit® Neis Vac-C®
13.03 Menthol in Aqueous cream 
  • Menthoderm
  • Dermacool-££

Over the counter preparation suitable for self-care/purchase if appropriate

05.04 Mepacrine 
13.15 Mepacrine Hydrochloride 

For Discoid lupus erythematosus (DLE)

See Chapter 5, section 05.04.04

A5.04.02 Mepiform® 

Specialist recommendation only
Silicone sheet for scar treatment
Type of wound product is suitable for
Not for use on open wounds- to be applied on healed scar only.
This is not a dressing but a scar treatment
Duration dressing remains on wound before changing
23 hours
Frequency of dressing change
Daily
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use on open or infected wounds. Do not use on skin affected by acne. Discontinue use if a rash or itching occur.
Rationale for inclusion in formulary
Scar therapy
Silicone sheets have been shown to soften, flatten scarring aiding movement, nerve sensations and function.
Cost effective.

A5.02.03 Mepitel® 

Specialist recommendation only

Soft polymer non-adherent dressing without pad

Type of wound product is suitable for
Primary wound contact layer, non adherent, traumatic and chronic wounds
Requires secondary dressing

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Heavily bleeding wounds
Any sensitivity to silicone

Rationale for inclusion in formulary
Non-adherent primary wound contact layer to protect skin tears, fragile skin, primary contact layer for use under topical negative pressure

15.02 Mepivacaine Scandonest Plain®

Hospital only

03.14 Mepolizumab Nucala®

In line with NICE

19.03 Mepore®  Type of wound product is suitable for
Post operative closed surgical wounds or simple wounds with up to light amounts of exudate.
Can be used as a protective dressing for sutured post operative wounds. Can be used as a protective dressing for newly epithelialized wounds. Can be used for small traumatic wounds.

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
1-7 days. If daily change is required - review product choice

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity

Rationale for inclusion in formulary
Sutured surgical wounds for protection. Can be used as a protective dressing for newly epithelialized wounds. Can be used for small traumatic wounds.
A5.01.02 Mepore® 

Type of wound product is suitable for
Post operative closed surgical wounds or simple wounds with up to light amounts of exudate.
Can be used as a protective dressing for sutured post operative wounds. Can be used as a protective dressing for newly epithelialized wounds. Can be used for small traumatic wounds.
Duration dressing remains on wound before changing
Up to 7 days
Frequency of dressing change
1-7 days. If daily change is required - review product choice
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity
Rationale for inclusion in formulary
Sutured surgical wounds for protection. Can be used as a protective dressing for newly epithelialized wounds. Can be used for small traumatic wounds.

04.07.02 Meptazinol Meptid®
09.08.01 Mercaptamine Cystagon®

NHSE commissioned

Hospital use only

01.05.03 Mercaptopurine 

Maintenance of remission of acute ulcerative colitis and Crohn’s disease in adults – unlicensed but in line with national guidelines

For use in Inflammatory Bowel Disease (IBD) 

Walsall

Amber Initiation Amber Initiation- Walsall only 

Wolverhampton

Amber SC Amber Shared Care- Wolverhampton only

ESCA Mercaptopurine-Wolverhampton only

Sandwell 

Amber SC 
Amber Shared Care- Sandwell only

ESCA Mecaptopurine (Sandwell only)

 Dudley 

 Amber SC Amber Shared Care Dudley only

 ESCA Mecaptopurine (Dudley only)

08.01.03 Mercaptopurine 

Red for cancer indications

09.04 Meritene Shake 
  • Prescribed for liver patients, at request of UHB liver/dietetic team only
  • For patients with high protein needs and low phosphate requirements
  • Use for renal patients
  • Use in Liver/hepatobiliary and pancreatic conditions
  • Supported by an ESCA
03.13 Meropenem  
05.01.02.02 Meropenem 

Primary care-Amber Rec under agreed OPAT Pathway 

Secondary care-Microbiological advice 

05.01.02.02 Meropenem with vaborbactam Vaborem®
01.05 Mesalazine 

Mesalazines  should be prescribed by brand.

Please refer to Optimise Rx messages for the preferred brand to be prescribed.
 
Brands include – Pentasa®, Asacol®, Asacol MR®, Salofalk® (granules/enema), Mezavant XL®, Octasa®

08.01 Mesna 
07.03.01 Mestranol/norethisterone Norinyl-1®

Monophasic Standard Strength (21 Day preparation)

For patients who need high oestrogen 

For patients on anticonvulsant treatment

A5.15 Metanium ointment 

Preferred local option

Specialist recommendation only
Barrier preparation
Type of wound product is suitable for
For relief of the symptoms of nappy rash
Frequency of use
Spread the ointment thinly so the skin texture can be clearly seen through it. Repeat at each nappy change.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used on adults in conjunction with containment products for incontinence
due to the inclusion of light liquid and white paraffin in the ingredients, which will repel urine/faeces back onto the skin.
Any allergy to the listed ingredients
Overdose is unlikely when Metanium Nappy Rash Ointment is used as instructed for treating nappy rash. However, as this product contains titanium salicylate, accidental ingestion or excessive topical application could lead to symptoms of salicylate poisoning.
Rationale for inclusion in formulary
Dermatology approved

13.02.02 Metanium® 

On specialist recommendation only

Over the counter preparation suitable for self-care/purchase if appropriate

02.07 Metaraminol 
06.01.02.02 Metformin 

Check Optimise Rx for most cost effective brand 

06.01.02.02 Metformin 
06.01.02.02 Metformin 

For patients with swallowing difficulties only.

Tablets more cost effective.

06.01.02.02 Metformin 

Patients with swallowing difficulties

04.07.02 Methadone 

For use in opiod dependence, see section 4.10.3

04.10.03 Methadone 
04.10.03 Methadone 
04.10.03 Methadone 

For use under specialist addiction services

21 Methadone  
03.09 Methadone Hydrochloride 

For use in palliative care only

03.09 Methadone Hydrochloride  Physeptone ®

For Palliative care use only

03.09 Methadone Hydrochloride oral solution Metharose ®

For Palliative care use only

03.09 Methadone Hydrochloride oral solution Methadose ®

For Palliative care use only

03.09 Methadone Hydrochloride oral solution Physeptone ®

For Palliative care use only

03.09 Methadone Linctus 

For Palliative care use only

05.01.13 Methenamine hippurate 
  • On Microbiology/Urology advice
  • Prescribing to be retained by Secondary care
01.05.03 Methotrexate 

Tablets 2.5mg (2.5mg tablets preferred as per NPSA alert)

Cytotoxic - do not crush and disperse in water

For use in active Crohn's disease

For specialist initiation only

Wolverhampton
Amber SC Amber Shared Care Wolverhampton only

 ESCA :Methotrexate (Wolverhampton only)

Walsall

Amber Initiation Amber Initiation Walsall only 

Sandwell 

 Amber SC Amber Shared Care Sandwell only

 ESCA:Methotrexate in active Crohn's disease (Sandwell only)

 Dudley 

 Amber SC Amber Shared Care Dudley only

ESCA:Methotrexate (Dudley only)

03.12 Methotrexate 

Sandwell

Amber SC  Amber SC Supported by ESCA

ESCA for Sandwelll

Walsall

Not on Formulary 

Dudley

Not on Formulary

Wolverhampton

Amber SC Amber SC Supported by ESCA

ESCA for Wolverhampton only

04.13 Methotrexate 

Specialist use only for neurological conditions

08.01.03 Methotrexate 

Commissioned by NHSE for treatment of cancer
Injection-hospital only

10.01.03 Methotrexate Metoject®

Metoject is APC preferred brand in view of additional patient safety characteristics

For use under the supervision of a specialist

Supported by an ESCA

Check cytotoxic disposal arrangements locally

10.01.03 Methotrexate 

Only 2.5mg tablets to be prescribed (Local agrement following National Patient Safety Agency (NPSA) alert)

Supported by an ESCA

To be prescribed once weekly as a single dose on the same day each week
 
Folic acid 5mg should normally be taken on the non methotrexate day
 
Cytotoxic, do not crush or disperse the tablets in water

13.05.03 Methotrexate 

Initiated by hospital only

ONCE WEEKLY DOSING

09.01.03 Methoxy polyethylene glycol-epoetin beta Mircera® •NHSE commissioned for use in renal dialysis
•Primary Care commissioned for use in cancer- in line with NICE TA323
13.05.02 Methoxypsoralen 
13.08.01 Methyl aminolevulinate Metvix®
02.05.02 Methyldopa 
04.04 Methylphenidate 

Please note that commissioning discussion is underway. However the present status is as follows:-

Amber SC Age 6 and over - Solihull practices.  Supported with ESCA

 

Amber SC Age 16 and over - Birmingham practices.  Supported with ESCA

 

Red Age under 16 - Birmingham practices


Amber SC  Age 6 and over - Sandwell and West Birmingham CCG.  Supported with ESCA

Amber SC  Supported with an ESCA -Sandwell & West Birmingham CCG for patients seen by the Black Country ADHD Services

                The immediate release preparation may be prescribed generically 
 

04.04 Methylphenidate 

Please note that commissioning discussion is underway. However the present status is as follows:-

Amber SC  Age 6 and over - Solihull practices.  Supported with ESCA


Amber SC Age 16 and over - Birmingham practices.  Supported with ESCA

 

Red Age under 16 - Birmingham practices


Amber SC Age 6 and over - Sandwell and West Birmingham CCG.  Supported with ESCA

 

Amber SC  Supported with an ESCA - Sandwell & West Birmingham CCG for patients seen by the Black Country ADHD Services

                

02.05 Metirosine 
01.02 Metoclopramide 

Nausea and vomiting


Not recommended for patients under 20 years of age due to risk of dystonic reactions


For restrictions for use in younger patients see MHRA guidance below

04.06 Metoclopramide  Green Traffic Light  Palliative care

Red Traffic Light  All other indications
04.06 Metoclopramide 

Tablets

SF solution £££££ - for patients with swallowing difficulties only

Nausea and vomiting

Not recommended for patients under 20 years of age due to risk of dystonic reactions 

For restrictions for use in younger patients see MHRA guidance below

02.02.01 Metolazone 

Specialist recommendation 

 

02.04 Metoprolol tartrate 
02.04 Metoprolol tartrate 
06.02.01 Metoprolol Tartrate 
  • BETALOC
05.01.11 Metronidazole 
05.01.11 Metronidazole 
05.01.11 Metronidazole 

Tablets 

Suspension £££££

05.04 Metronidazole Rozex ®

For acne rosacea only NOT infected wounds.

05.04 Metronidazole Zidoval®
05.04 Metronidazole Anabact®

For wounds, malodorous tumours and skin ulcers.

05.04 Metronidazole Metrogel®
05.04 Metronidazole 
05.04 Metronidazole Acea ®

For acne rosacea only NOT infected wounds.

05.04 Metronidazole Rosiced®
05.04 Metronidazole  
A5.16 Metronidazole  Anabact®

Specialist recommendation only
Type of wound product is suitable for
Malodourous fungating wounds
Requires a secondary dressing
Duration dressing remains on wound before changing
Apply 1-2 times daily following cleansing
Frequency of dressing change
1-2 times daily for a maximum of 8 weeks
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Avoid exposure to strong sunlight or UV light
Not to be used on a patient with known sensitivity to any components
avoid contact with eyes
Not for use on any other aetiology of wound as odour control
Rationale for inclusion in formulary
Odour control for fungating tumours

06.07 Metyrapone Metopirone®
10.02.02 Mexiletine 167mg hard capsules Namuscla®

In line with NICE 

For use in Ventricular Arrythmia use this link to Chapter 2

02.03.02 Mexiletine hydrochloride 
02.03.02 Mexiletine unlicensed special 
05.02.04 Micafungin 
07.02.02 Miconazole Gyno-Daktarin®
  • 2% intravaginal cream
  • 1.2g ovule (vaginal capsule) - discontinued by manufacturer 2018
12.03.02 Miconazole 
11.03.02 Miconazole 1% eye drops 
13.10.02 Miconazole 2% 

Dot Cream
Dot Dusting powder

04.08.02 Midazolam  Buccolam®

On specialist advice

15.01.04.01 Midazolam  Green Traffic Light  Palliative care

Red Traffic Light  All other indications-hospital only
02.07 Midodrine 

Use current status at Place/Trust

Sandwell 

Amber SC

ESCA Midodrine- Sandwell only

Wolverhampton

Amber Initiation

Walsall

Red

Dudley 

Unclassified 

 

 

08.01.05 Midostaurin Rydapt®

In line with NICE

08.02.04 Mifamurtide 

In line with NICE

07.01.02 Mifepristone Mifegyne® For Specialist/ Hospital Use Only
04.07.04 Migraleve ® pink 
02.05 Milrinone Primacor®
02.05.01 Minoxidil Loniten®

Use on specialist advice only

07.04.02 Mirabegron Betmiga®

Specialist Initiated

In line with NICE

For patients not tolerating / with contra-indications to antimuscarinics
 
Only to be used instead of anticholinergics if:

Anticholinergics contraindicated
Severe side effects with anticholinergics
At least two anticholinergics not effective
 
Prescribing mirabegron in combination with anticholinergics is not supported by trial data and therefore non-formulary

04.03.04 Mirtazapine 
  • Tablets
  • Orodispersible tablets ££

 

21 Mirtazapine  
  •  Pain under Specialist Initiation.
  •  Limited RCT evidence, for 3rd or 4th line pain where patient has low mood.

 

01.03 Misoprostol 
01.03.04 Misoprostol Cytotec®

For specialist initiation only

08.01.02 Mitomycin 

Commissioned by NHSE
Hospital only

11.99.99.99 Mitomycin C 

Hospital only

08.01.05 Mitotane Lysodren®

Commissioned by NHSE

08.01.02 Mitoxantrone  

Commissioned by NHSE
Hospital only

15.01.05 Mivacurium Chloride Mivacron®

Hospital only

09.04 MMA/PA A,omp 5 
  • Methionine, threonine and valine free, and low isoleucine aa supplement
  • The only pre-measured sachet of methionine, threonine, valine free and low isoleucine amino acid supplement for patients with propionic acidaemia and methyl malonic acidaemia reliant on tube feeding. A pre-measured sachet is particularly important as most of our families with MSUD do not speak English as their first language so require pre-measured products
09.04 MMA/PA Anamix® Infant 
  • Amino acid supplement without methionine, threonine, valine and isoleucine for infants with propionic acidaemia and methyl malonic acidaemia
  • The only infant amino acid supplement without methionine, threonine, valine and isoleucine for patients with propionic acidaemia and methyl malonic acidaemia
  • Nutritional supplement for the dietary management of proven methylmalonic acidaemia or propionic acidaemia in children from birth to 3 years
04.03.02 Moclobemide 
04.04 Modafinil 
  • Specialist initiation only for use in narcolepsy
09.04 Modjul® Flavour System 

Flavouring preparations

  • For flavouring unpalatable flavouring amino acid supplements or feeds in inborn errors of metabolism
  • Essential for flavouring different unflavoured amino acid supplements in inborn errors of metabolism- particularly for non PKU conditions. They offer alternative flavours to Vitaflo pacs. This is important as amino acid formulations are unpalatable and unacceptable particularly for patients with late diagnosed conditions
  • They cannot be purchased from a supermarket
  • For use with unflavoured SHS products based on peptides or amino acids; not suitable for child under 6 months
09.04 Modulen IBD® 
  • Specialised formulas for specific clinical conditions
  • For treatment of Crohn’s Disease
  • Crohn's disease active phase, and in remission if malnourished
08.01.05 Mogamulizumab Poteligeo®

In line with NICE

03.02 Mometasone  
12.02.01 Mometasone Furoate 
13.04 Mometasone Furoate 0.1% 

Potency - potent
Dot Cream
Dot Ointment
Dot Scalp lotion £££
DotAvoid prolonged use in children
DotPrescribe as acute prescription for 7 - 14 days only

09.04 Monogen® 
  • Specialised formulas: Infant and child: MCT-enhanced formula
  • Used in infants who require high MCT feed eg following chylothorax and in inborn errors of metabolism where MCT is required
  • Also essential for infants/children with long chain fatty acid oxidation disorders who need a high intake of MCT and high intake of carbohydrate e.g. LCHADD and trifunctional protein deficiency (i.e. lower carbohydrate formulas are inappropriate). There should always be 2 powdered high MCT formulae in the formulary in case of supply issues. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Long-chain acyl-CoA dehydrogenase deficiency (LCAD), carnitine palmitoyl transferase deficiency (CPTD), primary and secondary lipoprotein lipase deficiency, chylothorax, and lymphangiectasia
03.03.02 Montelukast 

Use in line with recommendations in BTS-SIGN asthma guideline

04.07.02 Morphine 

Green Traffic Light  Tablets

                M/R tablets

                M/R capsules

                Oral solution

                Injection

Red Traffic Light  Suppositories

                100mg/100ml PCA

                5mg/5ml intrathecal injection

                pre-filled syringe

Specialist initiation- pain clinic

Modified release(MR) preparation should be used for regular dosing. Immediate release preparations may be associated with tolerance and problem drug use.

Follow Optimise Rx advice for most cost effective brand / formulation

Injectable formulations for palliative care only

15.01.04.03 Morphine 

Hospital only in context of chapter 15.
See chapter 4 for other indications.

21 Morphine  
  • Topical use for painful wounds where systemic opioids are effective but dose limited due to side-effects
03.09 Morphine modified release capsule Zomorph®

For Palliative care use only

03.09 Morphine modified release tablet MST Continus ®

For Palliative care use only

03.09 Morphine oral solution 

For Palliative care use only

03.09 Morphine oral solution 

For Palliative care use only

03.09 Morphine solution for infusion 

For Palliative care use only

03.09 Morphine solution for injection 

For Palliative care use only

03.09 Morphine tablet Sevredol®

For Palliative care use only

05.01.12 Moxifloxacin 

Hospital use only under microbiological advice 

02.05.02 Moxonidine 
09.04 MSUD Amino 5 
  • Amino acid supplement without leucine, valine and isoleucine for infants/children with MSUD
  • The only pre-measured amino acid supplement, without leucine, valine, isoleucine for infants/children with maple syrup urine disease used for emergency regimens and tube feeds. This is particularly important as most of our families with MSUD do not speak English as their first language
09.04 MSUD Anamix® Infant 
  • Amino acid supplement without leucine, valine and isoleucine for infants with MSUD
  • The only infant amino acid supplement without leucine, valine, isoleucine for maple syrup urine disease
  • Nutritional supplement for the dietary management of proven maple syrup urine disease in children from birth to 3 years
09.04 MSUD Anamix® Junior 
  • Amino acid supplement without leucine, valine and isoleucine for children with MSUD
  • The only infant amino acid supplement without leucine, valine, isoleucine for maple syrup urine disease
  • Nutritional supplement for the dietary management of maple syrup urine disease in children 1–10 years
09.04 MSUD Anamix® Junior LQ 
  • Amino acid supplement without leucine, valine and isoleucine for children with MSUD
  • Can be used in adults
  • An unthickened powdered amino acid supplement without leucine, valine, isoleucine for children aged 1 to 10y with maple syrup urine disease which can be given as a drink
  • Nutritional supplement for the dietary management of maple syrup urine disease in children 1–10 years
09.04 MSUD cooler® 10 
  • Amino acid supplement without leucine, valine and isoleucine for children and adults with MSUD
  • An oral liquid amino acid supplement without leucine, valine, isoleucine formulated for children aged 3 to 6 years with maple syrup urine disease. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
09.04 MSUD cooler® 15 
  • Amino acid supplement without leucine, valine and isoleucine for teenagers with MSUD
  • An oral liquid amino acid supplement without leucine, valine, isoleucine for children aged 7 to 12 years with maple syrup urine disease. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
09.04 MSUD cooler® 20 
  • Amino acid supplement without leucine, valine and isoleucine for teenagers and adults with MSUD
  • One of 2 oral flavoured liquid amino acid supplements without leucine, valine, isoleucine for teenagers over 12 years of age and adults. This age group need the larger pouches to meet their non-leucine protein requirements. It is important we have a choice of more than 1 product as compliance is poor. It is essential that patients are offered choice of more than 1 protein substitute
09.04 MSUD express® 15 
  • Amino acid supplement without leucine, valine and isoleucine for teenagers and adults with MSUD
  • The only powdered amino acid supplement without leucine, valine, isoleucine for 7 to 12-year olds with maple syrup urine disease. Larger sachets are unacceptable for this age group of children and provide in excess of protein requirements
  • Nutritional supplement for the dietary management of maple syrup urine disease in children over 8 years and adults
09.04 MSUD express® 20 
  • Amino acid supplement without leucine, valine and isoleucine for teenagers and adults with MSUD
  • The only powdered amino acid supplement without leucine, valine, isoleucine for teenagers and adults with maple syrup urine disease that will met their higher BCAA-free amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-methionine protein requirements
  • Nutritional supplement for the dietary management of maple syrup urine disease in children over 8 years and adults
09.04 MSUD Gel® 
  • Amino acid supplement without leucine, valine and isoleucine for children with MSUD
  • The only weaning (thickened) amino acid supplement without leucine, valine, isoleucine for infants/young children with maple syrup urine disease
  • Nutritional supplement for the dietary management of maple syrup urine disease in children 1–10 years
09.04 MSUD Lophlex® LQ 20 
  • Amino acid supplement without leucine, valine and isoleucine for teenagers and adults with MSUD
  • One of 2 oral flavoured amino acid supplement without leucine, valine, isoleucine for teenagers over 12 years of age and adults with maple syrup urine disease. They need the larger pouches to meet their BCAA-free amino acid requirements. It is important we have a choice of more than 1 product for this age group as compliance is poor. It is essential that patients are offered choice of more than 1 protein substitute
  • Nutritional supplement for the dietary management of maple syrup urine disease in children over 3 years
09.06.07 Multivitamin preparations Dalivit®

Patients should be referred to healthy start vitamins scheme where eligible.
Limit prescribing to patients with clinical deficiency. Dalivit and alternatives are available for purchase for general needs.

09.06.07 Multivitamin preparations Abidec®

Contains arachis ( peanut) oil
Patients should be referred to healthy start vitamins scheme where eligible.
Limit prescribing to patients with clinical deficiency. Abidec and alternatives are available for purchase for general needs.

09.06.07 Multivitamin Supplement Paravit-CF®

Specialist initiation or recommendation for GP initiation by specialist in Cystic Fibrosis

09.06.07 Multivitamins 
09.06.07 Multivitamins (vitamin capsules)  

Contains vitamin A, vitamin D, Vitamin C, and B bitamins (riboflavin, nicotinamide and thiamine)
Eligible patients should be referred to health start vitamins scheme.
Prescribing of vitamins should be limited to patients with clinical deficiencies or malabsorption syndromes.

12.02.03 Mupirocin 2%  Bactroban Nasal®
13.10.01.01 Mupirocin 2% Bactroban®

Please refer to Primary Care Antimicrobial Guidelines

04.13 Mycophenolate 

Specialist use only for neurological conditions

13.05.03 Mycophenolate 

In line with ESCA (to be developed)

08.02.01 Mycophenolate Mofetil  

Prescribing to remain with the specialist for this patient group

Red Traffic Light  Renal Post transplant- new patients
  Renal Post transplant-patients initiated pre April 2013

For use in connective tissue diseases (Rheumatology), click here

10.02.01 Mycophenolate mofetil 

For use in connective tissue diseases

For specialist initiation and dose stabilisation

Supported by an ESCA

20 N acetyl cysteine 

For use in endoscopy

19.01 N-A® Ultra  Type of wound product is suitable for
For flat granulating and epithelising wound for non to heavy exudate levels where adherence may occur. To be used as a primary dressing with a secondary for absorption.

Duration dressing remains on wound before changing
7 days maximum

Frequency of dressing change
1-7 days, depending on levels of exudate

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity eg silicone. Use with care if wound is bleeding heavily.

Rationale for inclusion in formulary
To be used to reduce adherence to wound bed.
A5.01.01 N-A® Ultra 

Preferred local option

Type of wound product is suitable for
For flat granulating and epithelising wound for non to heavy exudate levels where adherence may occur. To be used as a primary dressing with a secondary for absorption.

Duration dressing remains on wound before changing
7 days maximum

Frequency of dressing change
1-7 days, depending on levels of exudate

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity eg silicone. Use with care if wound is bleeding heavily.

Rationale for inclusion in formulary
To be used to reduce adherence to wound bed.

03.07 N-Acetylcysteine nebulised 

Hospital only

02.06.04 Naftidrofuryl Oxalate 
01.06.06 Naldemedine Rizmoic®

For treating opioid-induced constipation in line with NICE

04.10.01 Nalmefene 

Restricted to Specialist Substance Misuse Services only (as per the local authority public health approved pathways)

Reach Out Recovery (CRI) in Birmingham. Single point of contact 24/7 Tel: 0121 227 5890 Link Reach Out Recovery website

Swanswell in Sandwell Tel: 0121 553 1333 Link to Swanswell website

SIAS in Solihull Tel:0121 301 3600 Link to SIAS website

The Nalmefen for reducung alcohol consumption technology appraisal (TA325) recommends this drug as a possible treatment for people with alcohol dependence who:

  • are still drinking more than 7.5 units per day (men) and more than 5 units per day (women) 2 weeks after an initial assessement and
  • do  not have physical withdrawal symptoms and
  • do not need to either stop drinking straight away or stop drinkling completely

The guidance also recommends that nalmefene should only be prescribed in conjunction with continuous psychosocial support focused on treatment adherence and reducing alcohol consumption

01.06.06 Naloxegol Moventig®

£££££

For treating opioid-induced constipation in line with NICE

04.10 Naloxone 
04.10.03 Naloxone 

Used to reverse opioid overdose

15.01.07 Naloxone 

Hospital only

04.10.01 Naltrexone 

Useful as an adjunct in the treatment of alcohol dependence after a successful withdrawal

04.10.03 Naltrexone Nalorex®

On recommendation from specialist service

10.01.01 Naproxen 

Naproxen EC tablets - Non-formulary

This has a half-life of 14 hours, so is useful if a sustained effect is required
 
Also indicated for use in dysmenorrhoea
 
Recommended for use in gout

08.02.04 Natalizumab Tysabri®

Commissioned by NHSE
Hospital only

02.04 Nebivolol 

Follow Optimise Rx advice for new initiations

06.01.01.03 Needle free administration device 

BRANDS

  • Injex 10ml vial adaptor pack
  • Injex 4 monthly refill pack
  • Injex ampoule pack
  • Injex starter set
  • InsuJet 10ml vial adaptor pack 5 pieces
  • InsuJet 3ml cartridge adaptor pack 5 pieces
  • InsuJet nozzle pack 5 pieces
  • InsuJet starter set
08.01.03 NelarabineRestricted Item  Atriance® Funding may be available from cancer drug fund
Hospital only
09.04 Neocate Syneo® 

Infant formula powder and is amino acid-based.

09.04 Neocate® Junior 
  • Infant and child: Amino acid-based formula
  • Replacement for Neocate Active and Neocate Advance on the formulary
  • Use in children over 12 mths who require amino acid based feed / have multiple food allergies
  • Used as tube or oral feed, provides complete nutritional support
  • For the dietary management of proven whole protein allergy, short bowel syndrome, intractable malabsorption and other gastrointestinal disorders where an amino acid diet is recommended, for children from 1 year onwards
  • ACBS Indications: Proven whole protein intolerance, short bowel syndrome, intractable malabsorption, or other gastro-intestinal disorders where an elemental diet is indicated
09.04 Neocate® LCP 
  • Infant and child: Amino acid-based formula
  • Use in infants ( birth – 12 months) who have multiple food allergies / faltering growth / require amino acid based feed as unable to tolerate standard or peptide feed. Used as tube and oral feed
  • Cows' milk allergy, multiple food protein intolerance, and conditions requiring an elemental diet
  • ACBS Indications: Proven whole protein intolerance, short bowel syndrome, intractable malabsorption, or other gastro-intestinal disorders where an elemental diet is indicated
11.04.02 Neodocromil Rapitil®
10.02.01 Neostigmine 
10.02.01 Neostigmine 

Hospital use only

15.01.06 Neostigmine metilsulfate 

Hospital only

09.04 Nepro® 
  • Specialised formulas for specific clinical conditions
  • Used for renal in and outpatients – adults only
  • Useful on occasion due to reduced Vitamin A content – adults only
  • Enteral feed or nutritional supplement in patients with chronic renal failure who are on haemodialysis or CAPD, or with cirrhosis, or other conditions requiring a high energy, low fluid, low electrolyte diet
  • Not suitable for child under 1 year; use with caution in child 1–5 years
08.01.05 Neratinib Nerlynx®

In line with NICE

05.03.01 Nevirapine 
05.03.01 Nevirapine Viramune®
02.06.02 Nicardipine Cardene®
05.05 Niclosamide 
02.06 Nicorandil Ikorel®

Specialist initiation

09.06.02 Nicotinamide 
13.06.01 Nicotinamide 4% 

3rd line

04.10.02 Nicotine replacement therapy 
02.06.02 Nifedipine  
07.01.03 Nifedipine 
21 Nifedipine  
  •  Hiccup, Tenesmus - Off-label use according to WMPCP Palliative Care Physicians Guidelines.
08.01.05 Nilotinib Tasigna®

Commissioned by NHSE

In line with NICE

02.06.02 Nimodipine Nimotop®
03.11 Nintedanib Vargatef®

Hospital ONLY

NHSE comissioned

In line with NICE and available from day 91 following publication of TA

03.11 Nintedanib Ofev®

Hospital only- NHSE commissioned

In line with NICE and available from day 91 following publication of TA

08.01.05 Niraparib Zejula®

Hospital Only

In line with NICE

05.03.01 Nirmatrelvir With Ritonavir 
05.01.07 Nitazoxanide Alinia®

For Hospital Use Only

05.04.04 Nitazoxanide  Not in BNF (Phase 2 trials)
09.08.01 Nitisinone Orfadin® NHSE commissioned
05.01.13 Nitrofurantoin 

Modified release capsules preferred formulation-First line

Oral Suspension £££££

15.01.02 Nitrous oxide  HOSPITAL ONLY
08.02.03 Nivolumab Opdivo®

Hospital Only

In line with NICE

01.03.01 Nizatidine 
19.31 NON-WOVEN FABRIC SWAB Drug Tariff Specification 28 Alternative to gauze
Lint/cotton, swabs/cotton wool should NOT be used - fibres can remain in the wound bed. Gauze should NOT be used as a primary dressing
02.07 Noradrenaline / Norepinephrine 
06.04 NORETHISTERONE 
07.03.02.01 Norethisterone Noriday®

Alternative to discontinued Micronor®

08.03.02 Norethisterone 
05.01.12 Norfloxacin 

Hospital use only under microbiological advice 

14.05 Normal immunoglobulin 

Normal immunoglobulin (IV or SC) is commissioned by NHS England not CCG

Red Traffic Light  For subcutaneous use:
Dot Gammanorm
Dot Hizentra
Dot Subcuvia
Dot Subgam

Red Traffic Light  For intravenous use:
Dot Flebogamma
Dot Gammaplex
Dot Octagam
Dot Vigam

Red Traffic Light  For intramuscular use

List of brands available for use:

  • Intratect (5%)
  • Gammaplex
  • Subgam
  • Hizentra
  • Privigen
  • Gamunex (10%)
  • Iqymune
  • Gammanorm
  • Octagam 10%
  • Panzyga
  • Cuvitru
  • Subcuvia
14.05.01 Normal immunoglobulin 

Red Traffic Light  Normal immunoglobulin for intramuscular use
 
Red Traffic Light  Normal immunoglobulin for subcutaneous use:
 

06.04.01.01 Novofem®  
10.02 Nusinersen Spinraza®

In line with NICE

09.09 Nutilis® Clear 
  • Recommended by SALTs for patients with dysphagia requiring thickened fluids
  • For thickening of liquids or foods in dysphagia. Not suitable for children under 3 years
  • Gum based products are generally preferred as they thicken to a more stable end point (unlike starch based products, they do not continue thickening over time) and provide a smoother texture, which improves acceptability and palatability for patients
09.04 Nutilis® Complete Stage 1  
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Used for dysphagia pts only
  • Where first line pre-thickened product – Slo Milkshake – is not suitable
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
09.04 Nutramigen® 1 with LGG (previous name Nutramigen® Lipil 1) 
  • Specialised formulas: Infant and child: Hydrolysate formula
  • Casein hydrolysate. Use in infants (from birth – 6 mths) who have cow’s milk protein intolerance / allergy
  • Tube or oral feed
  • Nutramigen has all the fat as LCT and CHO as glucose polymer and is more suitable for CMPI
  • If patient has a cow’s milk protein intolerance / allergy GP may initiate Nutramigen® Lipil 1 and refer to dietetics – in line NICE CG 116
  • Disaccharide and/or whole protein intolerance where additional medium chain triglycerides are not included
09.04 Nutramigen® 2 with LGG (previous name Nutramigen® Lipil 2) 
  • Specialised formulas: Infant and child: Hydrolysate formula
  • Casein hydrolysate. Use in infants from 6 mths who have cow’s milk protein intolerance/ allergy and soya intolerance/allergy
  • Tube or oral feed
  • If patient has a cow’s milk protein intolerance / allergy GP may initiate Nutramigen® Lipil 2 and refer to dietetics – in line NICE CG 116
  • Established disaccharide and/or whole protein intolerance (where additional chain triglycerides are not indicated)
  • Not suitable for child under 6 months
09.04 Nutramigen® Puramino 
  • Infant and child: Amino acid-based formula
  • Use in infants (birth – 12 months) who have multiple food allergies / faltering growth / require amino acid based feed. Unlike other products contains 33% MCT fat so useful in children requiring amino acid feed who also have fat malabsorption
  • Used as tube and oral feed
  • For use in the management of severe protein intolerance, multiple food intolerance and other gastro-intestinal disorders where an amino acid based diet is specifically indicated for infants and young children
  • ACBS Indications: Proven whole protein intolerance, short bowel syndrome, intractable malabsorption, or other gastro-intestinal disorders where an elemental diet is indicated
09.04 Nutricrem® 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Lactose free diet
  • Low energy per serving as a semi-solid supplement where low volume is required only
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–6 years.
09.04.02 Nutrini® 
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • 1 kcal feed without fibre, used in children 8-20kg. Up to 6 years.
  • Also essential low protein tube feed for children with inborn errors of protein metabolism (e.g. organic acidaemias, urea cycle disorders) aged 2 to 10y due to its low protein and amino profile as a source of natural protein. It is used when IMD children cannot tolerate fibre. To change to an alternative enteral feed with children with metabolic disorders would potentially require hospital admission to ensure stabilisation with a new enteral feed. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutrini® Low Enery Multi Fibre 

Child under 12 years

  • Low energy with fibre. 8-20kg
  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula except bowel fistula, in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutrini® Energy 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml tube feed for children over 8kg
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutrini® Energy Multi Fibre 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml tube feed for children over 8kg with added fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutrini® Multi fibre 
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • 1 kcal feed with fibre, used in children 8-20kg. Up to 6 years
  • Also, used in low protein tube feeds for children with inborn errors of protein metabolism (e.g. organic acidaemias, urea cycle disorders) aged 2 to 10y due to its protein and amino acid profile. It provides a source of natural protein. It is used in IMD children who can tolerate fibre. To change to an alternative enteral feed with children with metabolic disorders would potentially require hospital admission to ensure stabilisation with a new enteral feed. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient.
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutrini® Peptisorb 
  • Hydrolysate formula
  • 1.0kcal/ml polymeric feed used 8 -20kg where hydrolysed protein is required
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg Follow trust guidance on use of acidic tube feeds.
09.04.02 Nutrini® Peptisorb Energy 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml hydrolysed protein feed used in children over 8kg where whole protein is not tolerated. Additional information re pH of the product?
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–6 years, body-weight 8–20 kg
09.04.02 Nutriprem® 1  

For premature infant up to 2kg

  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • Low birth - weight formula
09.04.02 Nutriprem® 2 

Child under 12 years

  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • Post discharge formula for pre-term infants
  • Catch-up growth in pre-term infants (less than 35 weeks at birth) and small for gestational-age infants up to 6 months corrected age
09.04.02 Nutriprem® 2 

Child under 12 years

  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • Post discharge formula for pre-term infants <34 weeks to aid growth, for immunocompromised infants
  • Catch-up growth in pre-term infants (less than 35 weeks at birth) and small for gestational-age infants up to 6 months corrected age
09.04.02 Nutrison Peptisorb Plus HEHP Liquid tube feed
  • For large volumes use Nutrison Peptisorb Plus HEHP. For small er volumes 200ml use Vital®1.5 kcal.
  • Nutrison Peptisorb Plus HEHP is a Food for Special Medical Purposes for use under medical supervision.
  • Nutrison Peptisorb Plus HEHP is a peptide based, nutritionally complete*, ready to use, high energy (1.5kcal/ml), high protein (7.5g/100ml, 20% of energy from protein) tube feed, for the dietary management of disease related malnutrition in patients with malabsorption and/or maldigestion.
  • Suitable as a sole source of nutrition.
  • ACBS approved: for adults with disease related malnutrition, short bowel syndrome, intractable malabsorption, bowel fistulae, inflammatory bowel disease, total gastrectomy and for the pre-operative preparation of patients who are malnourished.
09.04.02 Nutrison Peptisorb® 
  • 1 kcal/mL and less than 5g protein/100 mL
  • Peptide-based formula
  • Pts with malabsorption
  • Short bowel syndrome, intractable malabsoprtion, proven inflammatory bowel disease, bowel fistula.
  • Follow Trust guidance on use of acidic tube feeds
09.04.02 Nutrison® 

First line

  • 1 kcal/mL and less than 5 g protein/100 mL
  • Standard 1 kcal/mL. No fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® 1000 Complete Multi Fibre 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • 1000 kcal/L, nutritionally complete in 1 litre, low volume
  • Disease related malnutrition in patients with low energy and/or low fluid requirements
09.04.02 Nutrison® 1200 Complete Multi Fibre 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • 1200 kcal/L, nutritionally complete in 1 litre, low volume
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® 800 Complete Multi Fibre 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • 800 kcal/L, nutritionally complete in 1 litre, low volume
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for child under 6 years, not recommended for child 6 - 12 years
09.04.02 Nutrison® Concentrated 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High calorie (2000 kcal/L), low volume, low potassium
  • First line in CF and renal patients
09.04.02 Nutrison® Energy 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High energy feed
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® Energy Multi Fibre 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High energy feed with fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® MCT 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Pts with chyle leaks following upper GI surgery
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® Multi Fibre 

First line

  • 1 kcal/mL and less than 5 g protein/100 mL
  • Standard 1 kcal/mL, With fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® Protein Plus 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Lower calorie, high protein feed. Fibre free
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Nutrison® Protein Plus Multi Fibre 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Lower calorie, high protein feed. Added fibre
09.04.02 Nutrison® Soya 
  • 1 kcal/mL and less than 5g protein/100 mL
  • Soya protein formula
  • Dietary restriction or intolerance to standard feeds
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula; also cows'milk protein and lactose intolerance
09.04.02 Nutrison® Soya Multi Fibre 
  • 1 kcal/mL and less than 5g protein/100 mL
  • Soya protein formula
  • Dietary restriction or intolerance to standard feeds requiring fibre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
05.02 Nystatin 

Not sugar Free

12.03.02 Nystatin 100,000units/ml 

Do not prescribe as Sugar free (SF)

A5.05.02 Oakmed Option Wound Manager 

Specialist recommendation only

Wound drainage system consisting of a hydrocolloid adhesive wafer and a drainable drainage bag

Type of wound product is suitable for
Complex abdominal wounds, moderate to large fistula’s, orthopaedic wounds or
fungating wounds with high levels of exudate, that are unmanaged with conventional dressings.

Max duration dressing remains on wound before changing
Empty drainage bag as required. If no port for drainage, change as required.

Frequency of dressing change
As long as adhesive remains intact whilst being mindful of skin integrity

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product component sensitivity to hydrocolloid (Gelatine and Pectin)
Low to moderate exuding wounds
Do not use if a conventional dressing can manage the exudate levels

Rationale for inclusion in formulary
Various size selection with drainage ports and windows
For highly exuding wounds that conventional dressings cannot manage the exudate levels

01.09 Obeticholic acid Ocaliva®

NHSE commissioned

In line with NICE

08.02.03 Obinutuzumab Gazyvaro®

In line with NICE

Hospital only

08.02.03 Ocrelizumab Ocrevus®

Hospital Only

In line with NICE

11.08.02 Ocriplasmin Jetrea®
12.02.03 Octenidine hydrochloride Octenisan® ms Nasal gel
  • Classed as a medical device
  • Listed in drug tariff - 6ml tube
  • Added to the formulary as alternative to Bacroban® nasal ointmnet in view of supply issues
13.11.02 Octenisan antimicrobial wash lotion 

For MRSA skin decolonisation if chlorhexidine sensitivity is a problem.

13.01 Octenisan® 

For MRSA skin decolonisation , if chlorhexidine sensitivity is a problem 

01.09 Octreotide  For specialist gastroenterologist initiation for intestinal secretions
01.09 Octreotide  
06.05 OCTREOTIDE 

Olatuton - Red

Sandostatin - Red

Sandostatin LAR - Red

08.03.04.03 Octreotide Sandostatin Lar®

NHSE commissioned in cancer: Use the product with the lowest acquisition cost.

  Palliative Care Use Only

Red Traffic Light  For Oncology 

Red Traffic Light  For Acromegaly

08.03.04.03 Octreotide Sandostatin®

NHSE commissioned in cancer: Use the product with the lowest acquisition cost.

  Palliative Care Use Only

Red Traffic Light  For Oncology 

Red Traffic Light  For Acromegaly 

21 Octreotide 
  •  For high volume vomiting, increased gastric secretion.
06.04 Oestrogel® 
07.02.01 Oestrogens, Topical Estring®
07.02.01 Oestrogens, Topical Gynest®

CAUTION CONTAINS ARACHIS (PEANUT) OIL

Topical oestrogens should be used in the smallest effective amount to minimise systemic effects.

The risk of endometrial hyperplasia and carcinoma is increased when systemic oestrogens are administered alone for prolonged periods. The endometrial safety of long-term or repeated use of topical vaginal oestrogens is uncertain; treatment should be reviewed at least annually, with special consideration given to any symptoms of endometrial hyperplasia or carcinoma.

07.02.01 Oestrogens, Topical Ovestin®

Topical oestrogens should be used in the smallest effective amount to minimise systemic effects.

The risk of endometrial hyperplasia and carcinoma is increased when systemic oestrogens are administered alone for prolonged periods. The endometrial safety of long-term or repeated use of topical vaginal oestrogens is uncertain; treatment should be reviewed at least annually, with special consideration given to any symptoms of endometrial hyperplasia or carcinoma.

07.02.01 Oestrogens, Topical Ortho-Gynest®

Topical oestrogens should be used in the smallest effective amount to minimise systemic effects.

The risk of endometrial hyperplasia and carcinoma is increased when systemic oestrogens are administered alone for prolonged periods. The endometrial safety of long-term or repeated use of topical vaginal oestrogens is uncertain; treatment should be reviewed at least annually, with special consideration given to any symptoms of endometrial hyperplasia or carcinoma.

08.02.03 Ofatumumab Arzerra®

NHSE is responsible commissioner for its use in untreated chronic lymphocytic leukaemia (as per NICE TA344)

Hospital only

Use in line with NICE

05.01.12 Ofloxacin 

Hospital use only under microbiological advice /GUM

11.03.01 Ofloxacin 

For use on advice of specialist. Not be used for the treatment of bacterial conjunctivitis

04.02.01 Olanzapine 

Supported by ESCA

04.02.02 Olanzapine Embonate ZypAdhera®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

08.01.05 Olaparib Lynparza®

Hospital ONLY

NHSE commissioned

In line with NICE and available from day 91 following publication of TA

08.01.05 Olaratumab Lartruvo®

In line with NICE

12.01.03 Olive Oil Ear Drops 
11.04.02 Olopatadine Opatanol®

Sodium cromoglicate more cost effective

03.04.02 Omalizumab Xolair®

For specialist use only in line with NICE TAs

Commissioned by NHSE

03.14 Omalizumab Xolair®

For specialist use only in line with NICE guidance below

NHS England is the responsible commissioner for use in Asthma

 

13.05.03 Omalizumab 

In line with NICE

01.03.05 Omeprazole 

Capsules are more cost effective than tablets

Most brands of capsules can be opened and beads swallowed without crushing or can be mixed with food or drink

 

01.03.05 Omeprazole Dispersible tablets 

££ - Orodispersible tablets are significantly more expensive than capsules

For use in swallowing difficulties or via nasogastric tubes when beads in the capsules are too large and lansoprazole orodispersible are not acceptable (e.g. children with fine NG tubes)

01.03.05 Omeprazole IV 

Hospital use only

06.01.01.03 Omnican fine 
A5.07.05 Omnistrip® 

Adhesive wound closure strip
Type of wound product is suitable for
For atraumatic closure of minor wounds or surgical incisions
Require a secondary dressing
Duration dressing remains on wound before changing
As necessary, up to 14 days
Frequency of dressing change
As necessary
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None
Rationale for inclusion in formulary
Cost effective
Essential for closure of minor injuries

04.06 Ondansetron 

Preparations available:

  • Tablets
  • Melt tablets
  • Suppositories
  • Injection
  • SF syrup- for patients with swallowing difficulties only

    Red Traffic Light  Chemotherapy patients only
      Hyperemesis in pregnancy (off label)
      Palliative care (off label)
04.09.01 Opicapone Ongentys®

Second-line therapy to entacapone, in patients who fail to respond to, or are intolerant of, entacapone, in situations where apomorphine therapy has been considered

Supported by an ESCA

12.03.01 Orabase® 
12.03.01 Orahesive® 
01.04 Oral Rehydration Salts 

Follow OptimiseRx advice for most cost-effective prescribing option

01.04 Oral Rehydration Salts  Follow scriptswitch advice for cost-effective brand prescribing
09.02.01.02 Oral rehydration salts 
04.05.01 Orlistat 

Can prescribe in accordance with NICE guidance

Orlistat 60mg capsules - Over the counter preparation suitable for self-care/purchase if appropriate

05.03.04 Oseltamivir 

Green-For Primary Care- Green only during Flu season and on authorisation by NHS England/Department of Health & Social Care or via commissioned service for out of season supply

05.03.04 Oseltamivir Tamiflu®

Green-For Primary Care- Green only during Flu season and on authorisation by NHS England/Department of Health & Social Care or via commissioned service for out of season supply

08.01.05 Osimertinib 

In line with NICE

09.04.02 Osmolite 1.5kcal 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • High energy vegetarian fish oil free (Nil fibre)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Osmolite® 
  • 1 kcal/mL and less than 5 g protein/100 mL
  • Pt requires 1 kcal/mL, vegetarian feed fish oil free (Nil fibre)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
09.04.02 Osmolite® Plus 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Alternative standard feed, vegetarian fish oil free (1200 kcal/L) (Nil fibre)
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for child under 10 years.
09.05.02.02 Osvaren® 

Specialist recommendation

06.04.01.01 Ovestin ® 
04.01.02 Oxazepam 
04.08.01 Oxcarbazepine 

Tablets

Oral suspension

On specialist advice

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particluar manufacturer's product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

07.04.02 Oxybutynin 

Normal release tablets more cost effective.
Do not offer to frail older women.

07.04.02 Oxybutynin 

2.5mg and 5mg tablets ONLY

3mg tablets are non-formulary

13.12 Oxybutynin 

For hyperhidrosis (off label use)after trial of aluminium salts

07.04.02 Oxybutynin Hydrochloride Kentera®

Only to be used if patients benefit from oral oxybutynin but cannot tolerate the side effects or oral agents

04.07.02 Oxycodone 
04.07.02 Oxycodone 

Capsules

M/R tablets

SF solution

For patients who do not tolerate morphine

Specialist initiation
Pain clinic and palliative care use only

21 Oxycodone  
  •  With specialist advice, may be used for symptom control only where Morphine is not tolerated.

 

03.06 Oxygen 
03.06 Oxygen 
05.01.03 Oxytetracycline oral

Recommended by Dermatologist

13.06.02 Oxytetracycline 

•Topical treatments should be used first line.

•Oral antibiotics should be reserved for acne, if topical treatment is not adequately effective or if it is inappropriate.


Oxytetracycline - take 1 hour before food or on a empty stomach. Avoid calcium, iron and indigestion remedies at the same time.

Please refer to Primary Care Antimicrobial Guidelines

07.01.01 Oxytocin Syntocinon® For Specialist/ Hospital Use Only
09.06.02 Pabrinex 

Hospital only

08.01.05 Paclitaxel 

Funding may be available from the Cancer Drug Fund

In line with NICE

08.01.05 Paclitaxel albumin-bound Abraxane®

NHSE commissioned

In line with NICE

09.04.02 Paediasure® 
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • 1 kcal per ml low carbohydrate sip feed for children
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula in child 1–10 years, body-weight 8–30 kg
09.04.02 Paediasure® Peptide 
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • Peptide based sip feed used in pts with gut failure
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 1–10 years, body-weight 8–30 kg
09.04.02 Paediasure® Plus 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • Lower Carbohydrate, 1.5kcal/ml sip feed, used in children with CHO intolerance
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula in child 1–10 years, body-weight 8–30 kg
09.04.02 Paediasure® Plus 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • Lower Carbohydrate, 1.5kcal/ml sip feed, used in children with CHO intolerance
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula in child 1–10 years, body-weight 8–30 kg
09.04.02 Paediasure® Plus Fibre 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • Lower Carbohydrate, 1.5kcal/ml sip feed, used in children with CHO intolerance with added fibre
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula in child 1–10 years, body-weight 8–30 kg. Not suitable for use in child under 1 year
09.06.07 Paediatric Seravit® 
  • Used in children and low weight adults on very restricted diets who are not meeting vitamin and mineral requirements and in enteral feed patients
  • For use in infants - unflavoured vitamin and mineral supplement given to infants and young children on low protein or low-fat diets who require vitamin and mineral supplementation. There are no other powdered preparations available that meet the requirements of infants on very limited diets with inherited metabolic disorders of metabolism. It cannot be purchased from a supermarket. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Vitamin, mineral, and trace element supplement in infants and children with restrictive therapeutic diets
08.01.05 Palbociclib Ibrance®

In line with NICE

Hospital only-NHSE commissioned

04.02.02 Paliperidone Trevicta®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

04.02.02 Paliperidone  Xeplion®

The APC’s view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

05.03.05 Palivizumab Synagis®
04.06 Palonosetron Aloxi®
06.06 PAMIDRONATE DISODIUM 
01.09.04 Pancreatin Pancrex V®

For Specialist initiation

Counsel patient on need for adequate hydration

Prescribe by Brand only

Use brand and strength recommended by specialist

01.09.04 Pancreatin Creon 10,000 ®, Creon 25,000 ®

For specialist initiation

Counsel patient on need for adequate hydration

Prescribe by Brand only

Use brand and strength recommended by specialist

 

15.01.05 Pancuronium Bromide 

Hospital only

08.01.05 Panitumumab Vectibix®
08.01.05 Panobinostat Farydak®

Hospital only- NHSE commissioned

In line with NICE and available from day 91 following publication of TA

04.07.01 Paracetamol Perfal®
04.07.01 Paracetamol 

Tablets

SF suspension

500mg soluble tablets - high sodium content. Only for patients with swallowing difficulties

04.07.01 Paracetamol 
04.07.01 Paracetamol and codeine Co-codamol ®15/500

£££££

Limited evidence

Only for patients with swallowing difficulties

For elderly community who would not tolerate separate ingredients and to support a step down review

High sodium content

Tablets and capsules more cost effective

04.07.01 Paracetamol and codeine Co-codamol 30/500

Use with caution in patients over 65s

Contraindicated in children below the age of 12

Use in chronic pain only

04.07.01 Paracetamol and codeine Co-codamol 30/500

£££££

High sodium content 

Only for use in patients with swallowing difficulties

Tablets and capsules more cost effective

For use in chronic pain

04.07.01 Paracetamol and codeine Co-codamol 15/500

£££££

Limited evidence

For elderly community who would not tolerate separate ingredients and to support a step down review

04.08.02 Paraldehyde 
15.01.04.02 Parecoxib Dynastat®

Hospital only

09.03 Parenteral Nutrition (TPN or PN)  For hospital use only

09.06.04 Paricalcitol 

Hospital only

05.04 Paromomycin 

Unlicensed

04.03.03 Paroxetine 
09.04.01 Pasta 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Essential protein-free basic products. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein. 100g pasta = 10g protein
09.02.01.01 Patiromer Veltassa®

In line with NICE

Red In emergency care for acute life-threatening hyperkalaemia alongside standard care

Amber Initiation for people with persistent hyperkalaemia and chronic kidney disease stage 3b to 5 or heart failure, with RICaD

08.01.05 Pazopanib Votrient®
14.04 Pediacel® 
09.04.02 PEG feeding products  Usually via Homecare
08.01.05 Pegaspargase Oncaspar®

Hospital ONLY

NHSE commissioned

In line with NICE and available from day 91 following publication of TA

08.01.05 Pegcetacoplan Aspaveli®

In line with NICE

09.01.06 Pegfilgrastim  Hospital only
05.03 Peginterferon Alfa 

Hospital only

In line with NICE

05.03 Peginterferon Alfa Pegasys®

Hospital only

In line with NICE

08.02.04 Peginterferon Alfa 

Hospital only

In line with NICE

08.02.04 Peginterferon alfa-2a Pegasys ® Commissioned by NHSE for the treatment of Hepatitis B and C

08.02.04 Peginterferon alfa-2b ViraferonPeg Commissioned by NHSE for the treatment of Hepatitis B and C
08.02.04 Peginterferon beta-1a Plegridy®

In line with NICE

08.01.05 Pembrolizumab Keytruda®

Hospital Only

NHS England is responsible commisioner in line with NICE (see links below)

08.01.03 Pemetrexed Alimta®

Funding may be available from cancer drug fund
Hospital only

08.01.05 Pemigatinib Pemazyre®

Use in line with NICE

06.01.01.03 Penfine classic 
04.02.01 Penfluridol 
09.08.01 Penicillamine 

Specialist recommendation with ESCA

10.01.03 Penicillamine 

Supported by an ESCA

11.03.01 Penicillin 

Hospital use only on advice of specialist ophthalmologists

05.04 Pentamidine  
05.04 Pentamidine > Pentacarina 
05.04.08 Pentamidine Isetionate  Pantacarinat®
07.04.03 Pentosan polysulfate sodium Elmiron®

In line with NICE

01.02 Peppermint Oil 

Prescribe as capsules E/C 0.2ml

01.02 Peppermint water 

Peppermint water is an unlicensed special and should only be prescribed (initiation and maintenance) by specialists, where no suitable alternative exists

For specialist use only

01.01.02 Peptac 
09.04.02 Peptamen® 
  • 1 kcal/mL and less than 5g protein/100 mL
  • Peptide-based formula
  • Where hydrolysate is required
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula
09.04.02 Peptamen® AF 

Hospital use only

  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Used in critical care settings 
09.04.02 Peptamen® HN 
  • Less than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Step down from Peptamen® AF
  • Intolerance to other feed
  • Hydrolysate 1300 kcal/L nutritionally complete in 1 litre
  • For patients with malabsorption where requirements (high protein/low volume) cannot be met with a standard 1Kcal/ml MCT peptide feed. Used in liver/hepatobiliary disease/conditions
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula. Not suitable for child under 3 years
09.04.02 Peptamen® Junior 
  • Hydrolysate Formula
  • Powdered preparation only
  • Used in children requiring hydrolsate, ability to concentrate or dilute to meed specific calorie density requirements
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula, in child 1–10 years
09.04.02 Peptamen® Junior 
  • Hydrolysate Formula
  • Ready to use, neutral pH, 1kcal/ml
  • Short bowel syndrome, intractable malabsorption, proven inflammatory bowel disease, bowel fistula, in child 1–10 years
09.04.02 Peptamen® Junior Advance 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml hydrolysed protein feed used in children over 8kg where whole protein is not tolerated. Increased MCT for use in liver failure.
  • Intractable malabsorption, short-bowel syndrome, bowel fistula, and proven inflammatory bowel disease in child 1–10 years
04.08.01 Perampanel Fycompa®

On specialist advice with an ESCA 

MHRA Advice
When prescribing for epilepsy the patient should be assessed  to make a clinical judgement if the same manufacturer's product/brand is necessary taking into account factors such as seizure frequency and treatment history. Also take into account patient/carer related factors such as their negative perceptions about alternative products and/or other issues related to the patient such as co-morbid autism, mental health issues or learning disability

04.02.01 Pericyazine 

Supported by ESCA

£££££

02.05.05.01 Perindopril erbumine 

DO NOT PRESCRIBE as perindopril arginine salt-Perindopril arginine is Black on the formulary

13.10.04 Permethrin 5% Lyclear® Dermal Cream

Over the counter preparation suitable for self-care/purchase if appropriate

04.02.01 Perphenazine 

Supported by ESCA

14.04 Pertussis (acelluar) low dose with low dose diptheria, tetanus and inactivated poliomyelitis vaccine (dTap/IPV) Boostrix®-IPV, Repevax®
08.01.05 Pertuzumab Perjeta®

In line with NICE

Hospital only

04.07.02 Pethidine 
15.01.04.03 Pethidine 

Hospital only

02.08 Phenindione 

Use on the advice of a specialist only

04.08.01 Phenobarbital 

Tablets

Elixir

On specialist advice

MHRA Advice
Patients being treated for epilepsy should be maintained on a specific manufacturer's product

Safety Information 

Prescriptions for Phenobarbital for children should be prescribed as "unlicensed phenobarbital oral solution 50mg in 5ml (alcohol free)"   APC descision September 2021                                                               

01.07.03 Phenol 
13.14.07 Phenol 2% w/w in compound zinc paste BP 
02.05.04 Phenoxybenzamine  
05.01.01.01 Phenoxymethylpenicillin 
02.07 Phenylephrine 
11.05 Phenylephrine Hydrochloride Minims® Phenylephrine Hydrochloride Mydriatic. For use prior to eye procedure

Only for use in patients with known hypersensitivity to preservatives
04.08.01 Phenytoin 

Capsules

Suspension

On specialist advice

MHRA Advice
Patients being treated for epilepsy should be maintained on a specific manufacturer's product

09.04 Phlexy-10® Exchange System 
  • Tablets maybe used in pregnancy, when suffering from morning sickness
  • Nutritional supplement for the dietary management of phenylketonuria
09.04 Phlexy-Vits® 
  • Vitamin and mineral supplement for teenagers and adults with phenylketonuria and other inborn errors of protein metabolism
  • The only suitable low volume (powder and tablets) comprehensive vitamin and mineral supplement for teenagers and adults that has been formulated for patients with phenylketonuria and other inborn errors of protein metabolism requiring very restrictive diets. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • For use as a vitamin and mineral component of restricted therapeutic diets in children over 11 years and adults with phenylketonuria and similar amino acid abnormalities
03.09 Pholcodine Linctus, BP 

OTC preparation suitable for self-care/purchase if appropriate

03.09 Pholcodine Linctus, Strong, BP 

OTC preparation suitable for self-care/purchase if appropriate

09.05.02.01 Phosphate 

Hospital only

01.06.04 Phosphate enema 

Fletchers phosphate enema®

Fleet ready to use enema®

09.05.02.01 Phosphate supplements Phosphate-Sandoz®
01.06 Phosphates (rectal) 
09.06.06 Phytomenadione  Green Traffic Light  Konakion® MM and Konakion® MM Paediatric
Red Traffic Light  1mg capsules
A5.06.01 PICO products 

Specialist recommendation only
Consider standard interactive dressings first


Disposable and portable system designed to kick start wound healing. Required
components: One PICO device, 2 dressings per kit.
Type of wound product is suitable for
Acute, chronic, dehisced, partial thickness burns, flaps, grafts and traumatic wounds.
Duration dressing remains on wound before changing
Twice a week dressing change, PICO device weekly change
Frequency of dressing change
Determined by exudate levels.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
It should not be used on:
Confirmed and untreated osteomyelitis
Malignancy in wound bed or wound margins
Exposed blood vessels
Organs
Unexplored fistulae Necrotic wounds Anastomotic sites
Emergency airway aspiration
Pleural, mediastinal or chest tube drainage and surgical suction
Rationale for inclusion in formulary
These devices promote patient mobility at a cost effective price and is available on drug
tariff which other comparable models are not.

01.06.05 Picolax® 
11.06 Pilocarpine 

Used as add-on therapy. A darkly pigmented iris will tend to require higher strength products.

On Specialist Ophthalmologist Recommendation

21 Pilocarpine  
  • Oral use for dry mouth where routine oral mouth care and saliva substitutes have failed.

 

12.03.05 Pilocarpine Hydrochloride Salagen®
  • Licensed for the treatment of xerostomia (dry mouth) following irradiation for head and neck cancer; dry mouth and dry eyes in Sjögren's syndrome 
  • Effective only in patients who have residual salivary gland function
11.06 Pilocarpine Preservative Free 

Hospital only

13.05.03 Pimecrolimus Elidel®

In line with NICE

06.01.02.03 Pioglitazone 
05.01.01.04 Piperacillin and Tazobactam  For hospital use only
04.09.03 Piracetam 

Tablets

Oral solution

20 PIRENZEPINE 50mg tabs  Hospital only
04.02.03 Pirenzipine (unlicensed) 

Hospital use only

03.11 Pirfenidone Esbriet®

Hospital only - NHSE commissioned

05.01.01.05 Pivmecillinam Hydrochloride 
08.01.05 Pixantrone 
04.07.04.02 Pizotifen 
09.04.01 Pizza bases 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Important protein-free foods to provide important energy, assist dietary adherence and provide variety when natural protein tolerance is very limited. Necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein. One regular pizza likely to provide 20g + protein
09.04 PKU Air 15 
  • A liquid amino acid which is lower in calories for children and adults with phenylketonuria
09.04 PKU Air 20 
  • A supplement which is lower in calories for children and adults with phenylketonuria
09.04 PKU Anamix first spoon 
  • A supplement without phenylalanine for children with phenylketonuria
  • One of 2 powdered weaning (thickened) amino acid supplement without phenylalanine for infants/young children with phenylketonuria. The consistency can be adjusted to suit the developmental age of the older baby/toddler. This is our preferable product because it has added long chain fatty acids
  • Nutritional supplement for the dietary management of proven phenylketonuria in children from 6 months to 5 years
09.04 PKU Anamix® Infant 
  • A supplement without phenylalanine for infants with phenylketonuria
  • The only infant amino acid supplement without phenylalanine for infants with phenylketonuria
  • Nutritional supplement for the dietary management of proven phenylketonuria in children from birth to 3 years
09.04 PKU cooler 10® 
  • A supplement without phenylalanine for children and adults with phenylketonuria
  • An oral liquid amino acid supplement without phenylalanine formulated for children aged 3 to 6 years with phenylketonuria. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements. The 3 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of phenylketonuria in children over 3 years
09.04 PKU cooler 15® 
  • A supplement without phenylalanine for children and adults with phenylketonuria
  • One of three oral liquid amino acid supplements without phenylalanine for children aged 7 to 12 years with phenylketonuria. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
09.04 PKU cooler 20® 
  • A supplement without phenylalanine for teenagers and adults with phenylketonuria
  • One of 3 liquid amino acid supplement without phenylalanine for teenagers and adults (>12 years of age) with phenylketonuria that will meet their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-phenylalanine protein requirements. It is important there is a choice of more than 1 product for this age group as compliance is poor and the potential outcome of poor compliance. The 3 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of phenylketonuria in children over 3 years
09.04 PKU Explore 10® 
  • Contains 10g of protein equivalent
  • Contains all the vitamins, minerals adn consists of low fat and low carbohydrate
09.04 PKU Explore 5® 
  • Contains 5g of protein equivalent
  • Contains all the vitamins, minerals adn consists of low fat and low carbohydrates
09.04 PKU express15® 
  • A supplement without phenylalanine for teenagers and adults with phenylketonuria
  • The only powdered amino acid supplement without phenylalanine for 7 to 12-year olds with phenylketonuria. Larger sachets are unacceptable for this age group of children and provide in excess of protein requirements
  • Nutritional supplement for the dietary management of phenylketonuria. Not recommended for children under 3 years
09.04 PKU express20® 
  • A supplement without phenylalanine for teenagers and adults with phenylketonuria
  • One of 2 powdered amino acid supplement without phenylalanine for teenagers and adults with phenylketonuria that will meet their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-phenylalanine protein requirements. It is important there is a choice of more than 1 product for this age group as compliance is poor. The 2 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of phenylketonuria. Not recommended for children under 3 years
09.04 PKU Lophlex® LQ 10 
  • A supplement without phenylalanine for children and adults with phenylketonuria
  • One of three liquid amino acid supplement without phenylalanine formulated for children aged 3 to 6 years with phenylketonuria. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements. The 3 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of phenylketonuria in children over 4 years and adults including pregnant women
09.04 PKU Lophlex® LQ 20 
  • A supplement without phenylalanine for teenagers and adults with phenylketonuria
  • One of 3 liquid amino acid supplements without phenylalanine for teenagers and adults (>12 years of age) with phenylketonuria that will met their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-phenylalanine protein requirements. It is important there is a choice of more than 1 product for this age group as compliance is poor. The 3 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of phenylketonuria in children over 4 years and adults including pregnant women
09.04 PKU sphere 15 
  • A low phenylalanine supplement derived from whey protein for children and adults with phenylketonuria. It is more palatable than amino acid supplements and associated with better utilisation of protein. Very useful for adult patients trying to return to diet or children / adults struggling to take their amino acid product because of its taste. Suitable from aged 4 years
09.04 PKU Sphere 20 
  • A low phenylalanine supplement derived from whey protein for children and adults with phenylketonuria. It is more palatable than amino acid supplements and associated with better utilisation of protein. Very useful for adult patients trying to return to diet or children / adult struggling to take their amino acid product because of its taste. Suitable from aged 4 years
09.04 PKU Start® 
  • For use in the dietary management of phenylketonuria
  • Amino acid supplement. Without phenylalanine for infants with phenylketonuria
09.01.07 Plerixafor  Hospital only, NHSE commissioned.
14.04 Pneumococcal polysaccharide conjugate vaccine (adsorbed) Synflorix®
14.04 Pneumococcal polysaccharide conjugate vaccine (adsorbed) Prevenar 13®

Protects against 13 strands of pneumococcus
For use in:
Dot the childhood immunisation programme
Dot individuals with an underlying medical condition which puts them at increased risk from pneumococcal disease.

14.04 Pneumococcal polysaccharide vaccine Pneumovax®

23-valent pneumococcal polysaccharide vaccine (PPV) containing 23-serotypes
 

13.07 Podophyllotoxin Condyline®
13.07 Podophyllotoxin Warticon®
13.07 Podophyllum 
08.01.05 Polatuzumab Polivy®

Hospital use only

Use in line with NICE

14.04 Poliomyelitis Vaccine inactivated (Salk) 

The polio vaccine is only given as part of combined products:

  • diphtheria/tetanus/acelluar pertussis/inactivated polio vaccine/Haemophilus influenzae type b (dTaP/IPV/Hib)
  • diphtheria/tetanus/acelluar pertussis/inactivated polio vaccine (DTaP/IPV or dTaP/IPV)
  • tetanus/diphtheria/inactivated polio vaccine (Td/IPV)
09.04 Polycal® 
  • High-energy supplements: carbohydrate
  • Ready to use. Requires no specific instruction to prepare e.g. energy supplement/ used as pre and post bolus with patients with glycogen storage disease to prevent hypoglycaemia, also used in fatty acid oxidation disorders
  • There is no other liquid glucose supplement on ACBS prescription.
  • Also energy supplements/ used as pre-and post-bolus tube feeds with patients with glycogen storage disease to prevent hypoglycaemia. Also use as a quick access, liquid energy supplement in patients with fatty acid oxidation disorders. There is no other liquid glucose supplement on ACBS prescription. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high or readily available carbohydrate supplement
A5.17 Polyfax®  Hospital use only
Type of wound product is suitable for
Partial thickness facial burns and healing graft sites, infected/colonised wounds

2 days or 2-3 times a day depending on injury site and type (as directed by Burns team)
Frequency of dressing change
2 days or 2-3 times a day
Caution/contraindications (when not to use the dressing, patient groups to avoid etc)
Allergy to Polymixin B sulphate or Bacitracin zinc
No more than 200g of Polyfax ointment per day
Rationale for inclusion in formulary
Prevent and treat bacterial infections in burns
A5.07.01 Polyfield Nitrile Patient Pack 

Sterile dressing pack
Type of wound product is suitable for
To be used on all wounds requiring aseptic dressing procedures
Duration dressing remains on wound before changing
Single use
Frequency of dressing change
Determined by wound type
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None listed
Rationale for inclusion in formulary
Available on drug tariff, cost effective and incorporates a measure guide which would
be an additional cost with other packs

A5.02.05 PolyMem® 

Specialist recommendation only

Foam dressing that contains a cleansing agent and glycerol

Type of wound product is suitable for
Low to moderately exuding wound including skin tears, and other traumatic wounds,
superficial and partial thickness wounds, burns, donor and graft sites and radiotherapy induces reactions

Duration dressing remains on wound before changing
2-7 days

Frequency of dressing change
Up to 7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Sensitivity to ingredients contained within the dressing
Not for full thickness burns Not for ischaemic wounds Not for diabetic foot wounds
Not in conjunction with solutions containing hypochlorite

Rationale for inclusion in formulary
Suitable for fragile and sensitive skin, Soft and comformable,
Easy to redress awkward areas
Wide range of sizes including digit shaped dressings

14.04 Polysaccharide Typhoid Vaccine Typherix®
14.04 Polysaccharide Typhoid vaccine for injection Typhim Vi®
14.04 Polysaccharide vaccine with hepatitis A vaccine 
09.02.01.01 Polystyrene Sulphonate Resins 
13.09 Polytar ® 

Contains peanut oil

Over the counter preparation suitable for self-care/purchase if appropriate

13.09 Polytar Plus® 
  • contains peanut oil

Over the counter preparation suitable for self-care/purchase if appropriate

08.02.04 Pomalidomide Imnovid®

In line with NICE

08.01.05 Ponatinib Iclusig®

In line with NICE

08.02.04 Ponesimod Ponvory®

In line with NICE

03.05.02 Poractant Alfa Curosurf®

For Hospital use only

Commissioned by NHSE

05.02.01 Posaconazole 
09.05.02.01 Potassium acid phosphate 
09.02.01.01 Potassium chloride  

Green Traffic Light 
Dot Potassium Chloride efferevescent tablets (Sando-K®)
Dot Potassium Chloride MR tablets (Slow-K®)


  SF syrup (Kay-Cee-L®) specialist recommendation only

09.02.02.01 Potassium Chloride and Glucose Intravenous Infusion  

Hospital use only

09.02.02.01 Potassium Chloride and Sodium Chloride Intravenous Infusion 

Hospital use only

09.02.02.01 Potassium Chloride Concentrate (Sterile) 

Hospital use only

09.02.02.01 Potassium Chloride, Sodium Chloride and Glucose Intravenous Infusion 

Hospital use only

07.04.03 Potassium citrate 
06.02.02 Potassium iodate 
06.02.02 Potassium iodide 
13.11.06 Potassium Permanganate 

SAFETY: Risk of death or serious harm if swallowed National Patient Safety Alert on the inadvertent oral administration of potassium permanganate April 2022.

If using or prescribing potassium permanganate ensure actions in alert are taken, including:

  • If to be used in a patient’s home, a risk assessment must be undertaken before prescribing
  • All patients must be supplied with a patient information leaflet
  • Include clear instructions on prescription to dilute before use
  • Do not issue on repeat prescription.
13.11.04 Povidone-iodine preparations 

Dot 10% antiseptic
Dot 10% ointment
Dot 7.5% surgical scrub

04.09.01 Pramipexole 

Please note that MODIFIED RELEASE preparation's are non-formulary and for existing patients only

07.02.01 Prasterone Intrarosa®

Approved by APC in July 2021

Place in thetrapy relevant to available treatments: 2nd

GP to seek specialist guidance prior to consideration

Prasterone is biochemically and biologically identical to endogenous dehydroepiandrosterone (DHEA), and is converted to oestrogens and androgens

02.09 Prasugrel Efient®

In line with NICE

02.12 Pravastatin  
05.05 Praziquantel 

Unlicensed

On Specialist advice only

05.05 Praziquantel > Cysticide 
03.02 Prednisolone 
03.12 Prednisolone 

•Plain tablets (not enteric coated)
•In conjunction with azathioprine for ILD

06.03 Prednisolone 
10.01.02.01 Prednisolone 

Do not prescribe EC tablets


Second line choice for the treatment of gout

10.01.02.01 Prednisolone 

Only for use in paediatric patients or patients with swallowing difficulties.
Prednisolone 5mg in 5ml oral solution is a cost effective alternative to soluble tablets.

10.01.02.01 Prednisolone 

Cost effective alternative to soluble tablets for paediatric patients and those with swallowing difficulties.

10.01.04 Prednisolone 

Second line for gout

Do not prescribe EC tablets

Prednisolone 5mg in 5ml oral solution is a cost effective alternative to soluble tablets for paediatric patients and those with swallowing difficulties.

11.04.01 Prednisolone  

For use on the advice of a specialist ophthalmologist

11.04.01 Prednisolone Pred Forte®

On specialist ophthalmologist recommendation

For the treatment of anterior uveitis in A&E-prednisolone acetate 1% as the drug of choice unless the patient has a preference for dexamethasone 0.1%

01.05.02 Prednisolone (oral) 

Tablets 5mg, EC2.5mg, 5mg, Soluble 25mg

Plain tablets are first line option

EC tablets are more expensive than plain tablets without any substantial evidence that they confer any GI benefits

25mg tablets are more expensive per mg than 5mg tablets

Soluble tablets are significantly more expensive than normal tablets which can be crushed and dispersed (unlicensed)

For short term use in acute exacerbation or "flare-ups" of relevant conditions

 

11.04.01 Prednisolone preservative free Minims SDU®

Restricted to those needing preservative free 

On specialist ophthalmologist recommendation

To be used in patients with severe Chronic Allergic Eye Disease who present to A&E with a flare up

04.03.04 Pregabalin 

£££££

For generalised anxiety disorder

Please follow Optimise Rx for most cost effective brand

04.07.03 Pregabalin 

4th line after duloxetine

On the advice of a specialist where duloxetine is unsuitable

Please be aware of abuse potential associated with this class of agent

From 17th July 2017, clinicians can now return to normal practice when prescribing pregabalin and no longer need to specify a brand name when prescribing for neuropathic pain

04.08.01 Pregabalin 

On advice of specialist

Please follow Optimise Rx for most cost effective brand

21 Pregabalin 
  • For pain.
  • Second line to Gabapentin if intolerant.
  • Useful if anxiety also present.

 

06.04.01.01 Premarin®  
06.04.01.01 Premique® low dose 
06.04.01.01 Premique® modified release 
15.02 Prilocaine Hydrochloride 1% Citanest®

Hospital only

15.02 Prilocaine Hydrochloride with Felypressin Citanest with Octapressin®

Hospital only

05.04.01 Primaquine 

 

04.08.01 Primidone 

On specialist advice

MHRA Advice
Patients being treated for epilepsy should be maintained on a specific manufacturer's product

04.09.03 Primidone 
10.01.04 Probenecid 
15.02 Procaine Hydrochloride 

Hospital only

05.01.01.01 Procaine Penicillin G 

for hospital use only as advised by GUM

09.04 Pro-Cal® Shot 
  • Protein, fat, and carbohydrate
  • Used where energy and protein is required in small volume – only on recommendation of dietitian
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat or carbohydrate (with protein) supplement
  • Not suitable for child under 3 years
09.04 Pro-Cal® Singles 
  • Protein, fat, and carbohydrate
  • Used where energy and protein is required in small volume, where measured doses are required – only on recommendation of dietitian
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat or carbohydrate (with protein) supplement
  • Not suitable for child under 3 years
08.01.05 Procarbazine 

Commissioned by NHSE

04.06 Prochlorperazine 

Inappropriate for elderly patients

Tablets

Buccal tablets

Syrup

Injection

04.02.03 Procyclidine 
04.09.02 Procyclidine 

Tablets

SF syrup

04.09.02 Procyclidine 

Injection

13.10.05 Proflavine cream BPC 

Hospital only

06.04.01.02 Progesterone  

    BRANDS

  • Cyclogest pessary 
  • Lutigest pessary 
06.04.01.02 Progesterone (micronised) Utrogestan ®
05.04 Proguanil  

Private Prescription in Praimary care

05.04 Proguanil > Paludrine 

Private prescription in Praimary care 

05.04.01 Proguanil Hydrochloride 

Private prescription in Primary Care

05.04 Proguanil Hydrochloride with Atovaquone 

Private prescription in Primary Care

06.04 Progynova TS patch 
06.04.01.01 Progynova® 

Progynova® 1mg and 2mg tablets

03.04.01 Promethazine 

OTC preparation suitable for self-care/purchase if appropriate

04.01.01 Promethazine Hydrochloride 
04.06 Promethazine hydrochloride 
A5.12 Prontosan Wound Irrigation solution 

See under antimicrobials

A5.03.04 Prontosan® Wound Gel  

Specialist recommendation only

A gel containing betaine, a surfactant to remove biofilm and debris and PHMB to help control bacterial bioburden.

Type of wound product is suitable for
Cleansing, decontamination and moisturising of acute and chronic wounds including 1st and 2nd degree burns.

Duration dressing remains on wound before changing
Apply at each dressing change

Frequency of dressing change
As determined by the wound and exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None

Rationale for inclusion in formulary
Gel to cleanse and decontaminate wounds
Antimicrobial
Breaks down biofilms in chronic wounds

A5.03.04 Prontosan® Wound Irrigation Solution 

Wound irrigation solution containing betaine a surfactant to remove biofilm and debris and PHMB to help control bacterial bioburden.
Type of wound product is suitable for
Cleansing, decontamination and moisturising of acute and chronic wounds including 1st and 2nd degree burns.
Duration dressing remains on wound before changing
Apply at each dressing change
Frequency of dressing change
As determined by the wound and exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None
Rationale for inclusion in formulary
Solution to cleanse and decontaminate wounds
Antimicrobial
Breaks down biofilms in chronic wounds
Can be used as an irrigation fluid with V.A.C. VERAFLO®

02.03.02 Propafenone 
13.12 Propantheline 

•For hyperhidrosis (licensed indication)
•Specialist recommendation

15.01.01 Propofol 

HOSPITAL ONLY

15.01.01 Propofol Diprivan®

HOSPITAL ONLY

02.04 Propranolol 
04.07.04.02 Propranolol 
04.09.03 Propranolol 
06.02 Propranolol 
06.02 Propranolol 

For Paediatric use 

02.04 Propranolol Hydrochloride Half-Inderal® LA
02.04 Propranolol Hydrochloride Inderal® LA
13.14.01 Propylene glycol 20% w/w in aqueous cream 
13.14.02 Propylene glycol 40% w/w in Dermovate® cream 
06.02.02 Propylthiouracil 
A5.15 ProShield 

Skin cleanser for use in patients with chronic diarrhoea or incontinence of urine.
Type of wound product is suitable for
To cleanse intact or injured skin from contamination of urine or faeces
Frequency of use
Apply at each episode of hygiene
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
External use only
Avoid contact with eyes
Known allergic sensitivity to any of the components
Keep out of reach of children
Rationale for inclusion in formulary
For skin cleansing related to incontinence.
Only skin cleanser available on drug tarrif

A5.15 ProShield Plus 

Skin protectant
Type of wound product is suitable for
To treat injured skin associated with incontinence where a dressing seal cannot be achieved
Frequency of use
Apply at each episode of hygiene
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
External use only
Avoid contact with eyes
Known allergic sensitivity to any of the components
Keep out of reach of children
Do not apply to pressure ulcers or leg ulcers
Not to be used as a first line barrier cream
Not to be used to protect peri wound
Not to be used as an emollient
Rationale for inclusion in formulary
For treatment of incontinence lesions where a standard dressing seal cannot be achieved

09.04 ProSource® Jelly 
  • High-energy supplements: protein
  • Liver/hepatobiliary disease/conditions
  • Other patients groups, based on clinical assessment
  • Pts requiring increased protein in a low volume
  • Hypoproteinaemia
  • Not recommended for child under 3 years
09.04 ProSource® Liquid 
  • Protein and carbohydrate
  • Pts requiring low volume, low cal, low CHO protein supplement (10g/30ml) for oral and tube feeders. Useful in allergy to milk and soya proteins. For high protein requirements
  • Liver/hepatobiliary disease/conditions
  • Biochemically proven hypoproteinaemia
  • Not recommended for child under 3 years
09.04 ProSource® Plus 
  • Protein and carbohydrate
  • Pts requiring low volume, low cal, low CHO protein supplement (15g/30ml) for oral and tube feeders
  • Useful in allergy to milk and soya proteins
  • Liver/hepatobiliary disease/conditions
  • Hypoproteinaemia
  • Not recommended for child under 3 years
09.04 ProSource® TF 
  • Protein and carbohydrate
  • Pts requiring low volume, low cal, low CHO protein supplement (11g/30ml) specifically formulated for tube feeders
  • Useful in allergy to milk and soya proteins
  • Low osmolality
  • Liver/hepatobiliary disease/conditions
02.08 Protamine 
05.01.09 Prothionamide 

Hospital use only under microbiological and Tuberculosis specialist advice 

02.11 Prothrombin complex injection 
09.04 Protifar® 
  • High-energy supplements: protein
  • High protein modular powder, to be added to other food, drink and feeds in a range of conditions
  • Nutritional supplement for use in biochemically proven hypoproteinaemia
09.04 ProZero® 
  • Low protein milk replacer in children and adults with inborn errors of protein metabolism on low protein diets
  • A protein-free milk in children and adults with inborn errors of protein metabolism on low protein diets. It contains equal calories per 100 ml to cow’s milk. It is particularly suitable for MSUD patients. Available in 1 litre /250 ml cartons. The dose and frequency of administration will be determined by the specialist dietitian
  • A protein-free nutritional supplement for the dietary management of inborn errors of metabolism in children over 6 months and adults
01.06.07 Prucalopride Resolor ®

 For use in men and women for chronic constipation

 Supported by a RICaD (in development)

03.10 Pseudoephedrine Hydrochloride 

OTC suitbale for self-care/purchase if appropraie

05.01.09 Pyrazinamide 

Pyrazinamide liquid 500mg in 5ml (unlicensed)

Hospital use only under microbiological and Tuberculosis specialist advice 

10.02.01 Pyridostigmine Bromide Mestinon®
09.06.02 Pyridoxine Hydrochloride 
05.04 Pyrimethamine Daraprim®
05.04 Pyrimethamine  
05.04 Pyrimethamine with Sulfadoxine Fansidar®
04.02.01 Quetiapine 
  • Supported by ESCA
  • Rationale for prescribing rather than first line antipsychotics to be provided with ESCA

    APC preferred brands, choose most cost effective option:
  • Biquelle XL
  • Sondate XL
  • Zaluron XL
  • Choose most cost-effective option
04.02.01 Quetiapine  
  • Prescribe standard release tablets
  • Supported by ESCA
06.07 Quinagolide Norprolac®
05.04 Quinine  
05.04 Quinine Bisulphate 
05.04 Quinine Dihydrochloride 
05.04.01 Quinine Sulphate 
10.02.02 Quinine Sulphate 

Short term use only - MHRA guidance

Not to be routinely prescribed for nocturnal leg cramps
 

14.05 Rabies immunoglobulin 

Use in line with protocol

16.01 Radium-223 Xofigosup>®
  • Hospital only- NHSE commissioned
  • In line with NICE and available from day 91 following publication of TA.
16.01 Radium-223 Xofigo®
  • Hospital only- NHSE commissioned
  • In line with NICE and available from day 91 following publication of TA.
16.06 Radium-223 Xofigo®
  • Hospital only- NHSE commissioned
  • In line with NICE and available from day 91 following publication of TA.
06.04.01.01 Raloxifene 
05.03.01 Raltegravir Isentress ®
08.01.03 Raltitrexed Tomudex®

Commissioned by NHSE - only for use in the context of appropriately designed clinical trials.
Hospital only

02.05.05.01 Ramipril 

Prescribe as capsules

11.08.02 Ranibizumab Lucentis®

Use in line with NICE

01.03.01 Ranitdine IV 

For specialist use only

01.03.01 Ranitidine 

For use in patients with swallowing difficulties or via nasogastric tubes only

01.03.01 Ranitidine  
01.03.01 Ranitidine 

The European Medicines Agency (EMA) Human Medicines Committee (CHMP) has recommended the suspension of all ranitidine medicines due to the presence of low levels of the impurity N-nitrosodimethylamine (NDMA). (30 April 2020)

 

 

02.06 Ranolazine Ranexa®

Use current status at Place/Trust

Sandwell

Amber Initiation Supported by RICaD

RICaD Ranolazine-Sandwell only

Wolverhampton

Amber Initiation

Walsall

Amber Initiation

Dudley

Amber Initiation

 

04.09.01 Rasagiline Azilect®
10.01.04 Rasburicase Fastertec®

Hospital only

09.01.03 Ravulizumab Ultomiris®

Use in line with NICE

13.14.07 Reflectant (Dundee) sunscreens coffee, coral pink, beige 

coffee

coral pink

beige

08.01.05 Regorafenib Stivarga®

In line with NICE

06.07 RELUGOLIX/ ESTRADIOL/ NORETHISTERONE ACETATE 
05.03 Remdesivir Veklury®
15.01.04.03 Remifentanil Ultiva®

Hospital only

09.04 Renapro® 
  • Specialised formulas for specific clinical conditions
  • For patients with high protein needs, low volume, low phosphate requirements.
  • Used in renal patients
  • Used in liver/hepatobiliary diseases/conditions
09.04 Renapro® shot 

Renapro Shot is described as "low fat, high protein and low carbohydrate"

  • For patients with high protein needs, low phosphate requirements
  • Used for renal patients
  • Used in liver/hepatobiliary diseases/conditions
  • Specialist dietician recommendation
09.04 Renastart® 
  • Specialised formulas for specific clinical conditions
  • Used in infants and children with renal disease when low Potassium and Low phosphate feed is required
  • Can be given orally or as a tube feed
  • Dietary management of renal failure in child from birth to 10 years
09.04 Renastep® 
  • ACBS criteria: For the dietary management of renal failure from 3 years of age
  • Ready to use high energy formula
  • Low in potassium, phosphate and vitamin A content
  • Patients with renal failure from 3 years of age
  • Use under medical supervision.
  • Not suitable for use as a sole source of nutrition.
  • Suitable from 3 years of age onwards.
  • Regular monitoring of nutritional status and electrolyte levels is required.
  • For enteral use only
A5.06.01 Renasys products 

Specialist recommendation only

The use of sub atmospheric pressure to promote or assist wound healing or to remove fluids from a site. Required components: Pump, Dressings foam or gauze, tubing and canister.
Type of wound product is suitable for
Acute, chronic and traumatic wounds. Can be used as a adjunct to surgery and for
salvage procedures such as wound dehiscence. Benefits are that it removes excess fluid that may contain bacterial pathogens, reduces soft tissue oedema, promotes granulation and provides a moist wound healing environment.
Consider standard interactive dressings first.
Duration dressing remains on wound before changing
Every three days
Frequency of dressing change
Determined by exudate levels. Different canister sizes available
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
It should not be used on: Grossly infected or bleeding wounds
Malignancy
Exposed blood vessels
Organs
Unexplored fistulae
Extensive necrotic wounds
Caution with foam, document the number inserted, ensure all pieces are retrieved.
Rationale for inclusion in formulary
It removes excess fluid that may contain bacterial pathogens, reduces soft tissue
oedema, promotes granulation and provides a moist wound healing environment. Both companies products are included due to different contracting arrangements. Can be used on large open wounds to increase speed of wound healing

09.06.07 Renavit® 

In line with ACBS criteria: Dietary management of water-soluble vitamin deficiency in adults with renal failure on dialysis

  • For renal patients as per APC formulary
  • Dietary management of water-soluble vitamin deficiency in adults with renal failure on dialysis
  • Dietary management of water-soluble vitamine deficiency in adults with renal failure on dialysis
09.04 Renilon® 7.5 
  • More than 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Low potassium, low phosphate sip feed
  • Dietetic advice
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula
  • Not suitable for child under 3 years; use with caution in child 3–5 years
06.01.02.03 Repaglinide 
14.04 Repevax®, Boostrix-IPV® 
03.14 Reslizumab Cinqaero®

For specialist use only in line with NICE

NHS England is the responsible commissioner for use in Asthma

09.04.02 Resource® Energy 
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Paediatrics and specialists adults use only
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for use in child under 3 years
09.04.02 Resource® Junior 

First Choice

  • Child: More than 1 kcal/mL and less than 4 g protein/100 mL
  • Alternative to Fortini, for patients who have taste fatigue - long term use
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula. Not suitable for use in child under 3 years
09.04 Resource® Optifibre 
  • High-fibre supplements
  • A fibre source added to oral and tube feeds
  • This is added to low protein tube feeds for patients with propionic acidaemia, methyl malonic acidaemia to provide a source of fibre. Children with these conditions become easily constipated leading to metabolic instability and hospital admissions so an additional source extra to fibre content of existing enteral feeds is essential. this product cannot be purchased from the supermarket and is essential. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula except dysphagia
  • Not suitable for child under 5 years
09.09 Resource® ThickenUp Clear 
  • Recommended by SALTs for patients with dysphagia requiring thickened fluids
  • Gum based products are generally preferred as they thicken to a more stable end point (unlike starch based products, they do not continue thickening over time) and provide a smoother texture, which improves acceptability and palatability for patients
02.10 Reteplase 

Hospital only 

14.04 Revaxis® 
05.03.05 Ribavirin 
08.01.05 Ribociclib Kisqali®

In line with NICE

Hospital only-NHSE commissioned

09.06.02 Riboflavin 

Specialist recommendation only for inherited metabolic diseases

05.01.09 Rifabutin 

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Rifampicin 

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Rifampicin 
13.06.02 Rifampicin 

Specialist initiation

05.01.09 Rifampicin and Isoniazid Rifinah® 300

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Rifampicin and Isoniazid Rifinah® 150

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Rifampicin and Isoniazid and Pyrazinamide Rifater®

Hospital use only under microbiological and Tuberculosis specialist advice 

05.01.09 Rifampicin, isoniazid, pyrazinamide and ethambutol Voractiv®

Hospital use only under microbiological and Tuberculosis specialist advice 

01.09 Rifaximin 

In line with NICE, supported by RICaD (In development) 

 

05.01.07 Rifaximin oral presentations
05.03.01 Rilpivirine hydrochloride Edurant®
05.03.01 Rilpivirine hydrochloride Rekambys®
04.09.03 Riluzole Rilutek®

Supported by an ESCA

09.02.02.01 Ringer's Solution for Injection 

Hospital use only

13.05.02 Risankizumab Skyrizi

In line with NICE

10.02 Risdiplam Evrysdi®

In line with NICE

06.06 RISEDRONATE SODIUM 30mg 
04.02.01 Risperidone 

Supported by ESCA

04.02.02 Risperidone  Risperdal Consta®

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

05.03.01 Ritonavir 
08.02.03 Rituximab MabThera®

NHSE is the responsible commissioner

In line with NICE

10.01.03 Rituximab (rheumatology) MabThera®

Hospital use only

Commissioned by NHSE for paediatrics (where adult TA available; anca-positive vasculitis; SLE; neuromyelitis optica

02.08 Rivaroxaban 

 



04.11 Rivastigmine 
  • Capsules
  • Patches - preferred brand is Alzest®
04.07.04.01 Rizatriptan 

Green Traffic Light  Tablets
Green Traffic Light  Orodispersible tablets SF-reserved for patients who are vomiting due to migraine

Black Traffic Light  Wafer/oral lyophilisates SF £££££

15.01.05 Rocuronium Bromide Esmeron®

Hospital only

03.03.03 Roflumilast Daxas®

In line with NICE 

09.01.04 Romiplostim Nplate® Hospital use only in line with NICE TA221.
06.06 ROMOSOZUMAB 

Evenity - Red

04.09.01 Ropinirole 

Brand preference SWB CCG Ippinia XL® (September 2020)

04.09.01 Ropinirole 

For use in Restless Legs, supported by an ESCA, see link below

04.09.04 Ropinirole 

For use in Restless Legs, supported by an ESCA, see link below

15.02 Ropivacaine Hydrochloride 75mg/10ml Naropin®

Hospital only

02.12 Rosuvastatin 

Restricted to patients unable to tolerate other low cost generic statins.

14.04 Rotavirus vaccine Rotarix®
04.09.01 Rotigotine 
08.01.05 Rucaparib Rubraca®

In line with NICE

04.08.01 Rufinamide 

For Lennox-Gastaut syndrome only

Supported by an ESCA

MHRA Advice
MHRA advises that when prescribing for epilepsy the patient should be assessed to make a clinical judgement if the same manufacturer's product/brand is necessary taking into account factors such as seizure frequency and treatment history. Also take into account patient/carer related factors such as their negative perceptions about alternative products and/or other issues related to the patient such as co-morbid autism, mental health issues or learning disability

08.01.05 Ruloxitinib Jakavi®

Hospital ONLY

NHS Engalnd is responsible commissioner

In line with NICE and available from day 91 following publication of TA

28.01 Ruxolitinib (INC424)  Incyte®

Approved for 2nd line compassionate treatment in patients with high risk myelofibrosis  (Cons. Haematologist)

09.04 S.O.S® 
  • High-energy supplements: carbohydrate
  • Individual dose sachets, to be made as needed –pre measured dose to be made up by parents
  • Essential for use in an emergency regimen in inborn errors of metabolism / module in tube feed for low amino acid or fat diets / energy supplement
  • Also essential core ingredient in emergency feeds for inborn errors of metabolism / or used as an Individual carbohydrate module in tube feeds for low amino acid or fat diets / or as an energy supplement. Particularly important to use with non-English speaking families and vulnerable families as it is supplied in pre-measured sachets. Research as shown that it is safer to use than conventional glucose polymer powders. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • For use as an emergency regimen in the dietary management of inborn errors of metabolism in adults and children from birth
02.05.05 Sacubitril valsartan Entresto®

Use current status at Place/Trust

Sandwell

Amber Initiation Supported by RICaD

Sacubatril valsartan(Entresto) RICaD -Sandwell only

Wolverhampton

Amber Initiation

Walsall

Amber Initiation

Dudley

Amber Initiation

Entresto-Implementation of Entresto (Sacubitril/Valsartan) in Dudley Health Economy

03.01.01.01 Salbutamol  
  • Salbutamol IV
  • Ventolin Solution for Infusion
  • Ventolin Solution for Injection
03.01.01.01 Salbutamol  

BRANDS/FORMULATION

  • Easyhaler
  • Ventolin Accuhaler
  • Salamol
  • Salamol Easi-Breathe

 

How to use a Metered Dose Inhaler
How to use a Metered Dose Inhaler with a Large Volume Spacer Device
How to use a Metered Dose Inhaler with a Small Volume Spacer Device
How to use an Accuhaler inhaler
How to use an Easyhaler Inhaler
How to use an Easi-Breathe Inhaler

03.01.01.01 Salbutamol  Nebuliser Liquid ®

Green Green-Nebuliser Liquid

 

Amber Recommended Amber Recommended- Nebuliser Liquid in Paediatrics

07.01.03 Salbutamol 
13.14.06 Salicylic acid 10% w/w in emulsifying ointment 
13.07 Salicylic Acid 16.7% with Lactic Acid 16.7% paint Salactol®

Over the counter preparation suitable for self-care/purchase if appropriate

13.14.06 Salicylic acid 2% w/w & sulphur 2% w/w in aqueous cream 
13.14.06 Salicylic acid 2% w/w in emulsifying ointment 
13.14.06 Salicylic acid 20% w/w in emulsifying ointment 
13.14.02 Salicylic acid 5% w/w & propylene glycol 47.5% w/w in Dermovate® cream 
13.14.06 Salicylic acid 5% w/w in emulsifying ointment 
13.07 Salicylic Acid gel Salatac®

Over the counter preparation suitable for self-care/purchase if appropriate

13.07 Salicylic Acid Ointment Verrugon®

Over the counter preparation suitable for self-care/purchase if appropriate

12.03.05 Saliveze® 

Dot Approved for ACBS conditions i.e. patients suffering from xerostomia (dry mouth) as a result of having or having undergone radiotherapy or sicca syndrome
Dot Palliative care
Dot Dental Practitioners

12.03.05 Salivix® 

Dot Approved for ACBS conditions i.e. patients suffering from xerostomia (dry mouth) as a result of having or having undergone radiotherapy or sicca syndrome.
Dot Palliative care
Dot Dental practitioners

Only useful in patients who have residual salivary gland function

09.05.01.01 Sandocal-1000® 
06.04 Sandrena gel 
09.04.01 Sapropterin Dihydrochloride  Kuvan®

Use in line with NICE

08.02.04 Sarilumab Kevzara®

In line with NICE

28.01 Sativex “Cannabis Extract” 

For muscle spasticity, to be funded by Neurosciences directorate

09.04.01 Savory meals and mixes 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc

  • Important protein-free foods to provide important energy, assist dietary adherence and provide variety when natural protein tolerance is very limited. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein-. 1 ordinary meal is likely to provide ≥25g protein
09.04 Scandishake® Mix 
  • Protein, fat, and carbohydrate
  • Second choice for patients with very high energy requirement eg. cystic fibrosis
  • In adults with cystic fibrosis, nutritional advice and interventions should be aimed at maintaining a BMI of 22kg/m2 in women and 23kg/m2 in men, as these are associated with better lung function (Nutritional management of CF – Consensus document – 2016)
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat or carbohydrate (with protein) supplement
  • Not suitable for child under 3 years
01.07.02 Scheriproct®  
13.05.02 Sebco® 
13.05.03 Secukinumab Cosentyx®

Specialist use only in line with NICE.

08.04 Selective internal radiation therapies 

In line with NICE

04.09.01 Selegiline Hydrochloride 

Tablets

Oral lyophilisate are reserved for patients with swallowing difficulties in advanced Parkinson's disease

09.05.05 Selenium  Selenase®

Specialist recommendation

09.05.05 Selenium  

Hospital only

13.09 Selenium Sulphide Selsun®

Over the counter preparation suitable for self-care/purchase if appropriate

08.01.05 Selpercatinib Retsevmo®

In line with NICE

06.01.02.03 Semaglutide Rybelsus®

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

 

Rybelsus is a tablet for once-daily oral use but has special administration directions:

    • It must be taken on an empty stomach at any time of the day.
    • Patients are required to wait at least 30 minutes before eating/drinking or taking other oral medicinal products. Waiting less than 30 minutes decreases absorption.
    • It should be swallowed whole with a sip of water (up to half a glass of water equivalent to 120 ml).

 

06.01.02.03 Semaglutide Wegovy ®

PLEASE PRESCRIBE BY BRAND NICE Guidance on prescribing

Semaglutide is a biological medicine. Biological medicines must be prescribed and dispensed by brand name, see Biological medicines and Biosimilar medicines, under Guidance on Prescribing; manufacturer advises to record the brand name and batch number after each administration.

 

The use of semaglutide for this indication is restricted to prescribing by commissioned clinics in secondary care by a consultant led specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Wegovy®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes.

 

01.06.02 Senna 

Tablets 7.5mg, Syrup 7.5mg/5ml

Syrup is currently more cost effective than tablets

Time to effect approximately 8 to 12 hours

05.01.04 Septopal 
04.03.03 Sertraline 
09.05.02.02 Sevelamer  

Specialist Recommendation
• No ESCA
• Common Practice

15.01.02 Sevoflurane 

HOSPITAL ONLY

02.05.01 Sildenafil 
10.04 Sildenafil tablets GENERIC 
  • Use in digital ulceration is commissioned by NHS England
  • All prescribing retained in Secondary Care
  • Off label use 
A5.16 Silver nitrate 

NOT 1ST LINE TREATMENT ONLY TO BE USED IN A CLINIC SETTING OR BY A CLINICAL SPECIALIST
Type of wound product is suitable for
For treatment of chronic overgranulation, non acute or weeping.
Duration product remains on wound before changing
Apply moistened caustic pencil tip for 1-2 mins, whilst protecting the surrounding skin with soft paraffin.
Frequency of use
Maximum treatment: 3 applications
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Keep away from the eyes
Not suitable for use on the face, ano-genital region or large areas
Not for untreated bacterial, fungal or viral skin lesions
Can cause chemical burns
Rationale for inclusion in formulary
Treatment of overgranulation

13.07 Silver nitrate 95% caustic applicator 
13.07 Silver Nitrate 95% with Potassium Nitrate 5% Caustic pencil AVOCA®

Over the counter preparation suitable for self-care/purchase if appropriate

13.07 Silver nitrate applicators 

Dot 40%
Dot 75%
Dot 95%

Over the counter preparation suitable for self-care/purchase if appropriate

13.10.01.01 Silver Sulfadiazine Flamazine®

For infected burns under specialist supervision

A5.17 Silver sulfadiazine 1% Flamazine®

Burns specialist recommendation only
Type of wound product is suitable for
Partial thickness & full thickness burn injuries. Sloughy burn wounds or areas of graft loss
Duration preparation remains on wound before changing
24-48 hours
Frequency of use
Daily- occasionally alternate day
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to any ingredients.
Not to use in pregnancy or breast feeding
Take care if: suffer kidney or liver problems, deficiency of the enzyme known as glucose
6- phosphate dehydrogenase. Taking tablets prescribed for epilepsy
Rationale for inclusion in formulary
Prevent and treat bacterial infections in burns, skin graft donor sites.

A5.17 Silver sulfadiazine 1.0g & Cerium nitrate 2.2g Flammercerium® Hospital use only
Type of wound product is suitable for
Partial thickness & full thickness burn injuries.
Duration preparation remains on wound before changing
24-48 hours
Frequency of use
Daily- occasionally alternate day
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy to any ingredients.
Not to use in pregnancy or breast feeding, infants or babies under the age of 2 years.
Take care if: suffer kidney or liver problems, deficiency of the enzyme known as glucose
6- phosphate dehydrogenase. Taking tablets prescribed for epilepsy
Rationale for inclusion in formulary
Prevent and treat bacterial infections in burns
01.01.01 Simeticone 

Drops

For use in infantile colic

03.09.02 Simple Linctus, BP 

OTC preparation suitable for self-care/purchase if appropriate

03.09.02 Simple Linctus, Paediatric BP 

OTC preparation suitable for self-care/purchase if appropriate

02.12 Simvastatin 
08.02.04 Siponimod Mayzent®

In line with NICE

08.02.02 Sirolimus Rapamune®

Commissioned by NHSE for post transplant patients.
Prescribing to remain with the specialist for this patient group

Red Traffic Light  Post transplant- if prescribing is NOT established with GP before 1st April 2013


  Post transplant- if prescribing IS established with GP before 1st April 2013

06.01.02.03 Sitagliptin 

To be used in line with NICE

First line treatment option where a DPP-4 inhibitor is indicated.


No significant clinical benefit when used in combination with Insulin – avoid using together

06.01.02.03 Sitagliptin and Metformin 

A variety of combinations tablets (dual therapies)
of oral diabetes medication can be prescribed and
are available in the Drug Tariff.


Overall, they may improve compliance in patients,
however some combinations would then not allow
the flexibility in dosing that is required for diabetes
management and in some cases increase the
tablet burden. There are specific sick-day rules
related to stopping certain medication which
would be further complicated where they are not
prescribed in their separate formulations.


Furthermore, for the overall health economy not
all combination therapies are cost-effective and
this will be increasingly so as the patents expire
over the near future. There are some combination
therapies that are not recommended in the oral
guidance and clinicians are guided to review and
discuss these with patients as part of shared -care
decision making.


There are complexities also around the lack of
licensing of dual therapies in specific cohorts of
patients, related to prescribing for the indication of
heart failure or renal disease, making this a
complex area for prescribing in primary care

A5.16 Skin tissue adhesive LiquiBand® Optima

Preferred local option

Tissue Adhesive
Type of wound product is suitable for
Closure of minor skin wounds from surgical incisions and simple traumatic lacerations
Duration dressing remains on wound before changing
Single application should be sufficient to close the wound. If this does not maintain the wound edges, refer to a medic for consideration of other wound closure
Frequency of dressing change
As necessary
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
May cause skin sensitivities
Do not use on any wound with evidence of active infection, gangrene or wounds of pressure aetiology
Do not use on mucosal surfaces or on skin that may be regularly exposed to bodily fluids or with dense natural hair
Do not use on patients with a known sensitivity to formaldehyde or cyanoacrylate
Rationale for inclusion in formulary
Necessary for closure of minor wounds

09.04 Slo drinks milkshakes 

First Line

  • For dysphagia pts only
  • Not suitable for CKD 4-5, renal pts
  • Not suitable for lactose intolerance
  • Not suitable for bile acid malabsorption or fat maldigestion associated with biliary diseases/conditions
  • To be made up with whole milk
  • Contains 24g protein per serving as served
09.09 SLO Drinks® 
  • Used in a complex specific patient group advised by a SALT specialist
  • Nutritional supplement for patient hydration in the dietary management of dysphagia
  • Not suitable for children under 3 years
09.04 SMA Althera® 
  • Cows' Milk Protein Allergy

  • Extensively hydrolysed formula
09.04 SMA LF® Lactose Free Formula (previous name SMA® LF) 
  • Specialised formulas: Infant and child: Residual lactose formula
  • Can be purchased over the counter
  • Only prescribable for patients who currently do not pay for formula feeds (eg healthy start scheme)
  • For infants with lactose intolerance
  • Proven lactose intolerance
09.04.02 SMA PRO High Energy (previous name SMA® High Energy 

Child under 12 years

  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • High energy feed for faltering growth
  • Single use only in acute setting – risk of increased waste
  • Once open must be used within 24 hours
  • Disease-related malnutrition, malabsorption, and growth failure in infancy
09.04.02 SMA® PRO Gold Prem 2 (previous name SMA® gold Prem 2 

Child under 12 years

  • Less than 1 kcal/mL and less than 4g protein/100 mL
  • Post discharge formula for pre term infants
  • Powder feed
  • Partially hydrolysed
  • For catch-up growth in preterm infants and small for gestational age babies on discharge from hospital until 6 months corrected age. It may be used as the sole source of nutrition until complementary feeding commences
01.06 Sodium acid phosphate with sodium phosphate 
01.03 Sodium alginate with calcium carbonate and sodium bicarbonate 
01.03 Sodium alginate with potassium bicarbonate 
10.01.03 Sodium aurothiomalate Myocrisin®

Supported by an ESCA

07.04.03 Sodium bicarbonate 
09.02.01.03 Sodium bicarbonate 

Specialist recommendation

12.01.03 Sodium Bicarbonate 5% 
09.02.02.01 Sodium bicarbonate infusion 

Hospital use only

03.01.05 Sodium Chloride 
09.02.01.02 Sodium chloride 
   

 Green Traffic Light  Sodium chloride M/R Tablets

 Red Traffic Light  Sodium chloride 5mmol solution

   Sodium chloride 1mmol/mL oral solution - Specialist recommendation

11.08.01 Sodium Chloride Minims® Saline

Hospital only

Diluent for impregnated dye strips

12.02.02 Sodium Chloride 
03.07 Sodium chloride 0.9% 
03.07 Sodium chloride 0.9% 
07.04.04 Sodium Chloride 0.9% 

For Specialist / Hospital Use Only

13.11.01 Sodium Chloride 0.9% 
21 Sodium chloride 0.9% 

 

11.08.01 Sodium Chloride 0.9% Solutions 

Hospital only - Theatre use

11.08.01 Sodium chloride 5% 

On Specialist Ophthalmologist Recommendation

11.08.01 Sodium Chloride 5% PF drops (Moorfields) 

On Specialist Ophthalmologist Recommendation

03.07 Sodium Chloride 7% 
09.02.02.01 Sodium Chloride and Glucose Intravenous Infusion 

Hospital use only

09.02.02.01 Sodium Chloride Intravenous infusion 

Hospital use only

07.04.04 Sodium Citrate 

Hospital Only

06.06 Sodium Clodronate Calsteon®, Loron 520®

 

Dudley 

Black

Sandwell

Amber SC

ESCA- Sandwell

Walsall

 Black

Wolverhampton

Red


 

11.04.02 Sodium Cromoglicate 
11.04.02 Sodium cromoglicate Catacrom®

On specialist ophthalmologist recommendation as Catacrom

09.01.01.01 Sodium Feredetate SF Elixir Sytron®
09.05.03 Sodium Flouride Toothpaste 0.619% (2800ppm) DPF 

Dental prescribing ONLY

09.05.03 Sodium Flouride Toothpaste 1.1% (5000ppm) DPF 

Dental prescribing ONLY

09.05.03 Sodium Fluoride Mouthwash BP 

Dental prescribing ONLY

05.01.07 Sodium fusidate 
05.01.07 Sodium fusidate  
11.08.01 Sodium Hyaluronate 0.15% Multi Hyabak®

On Specialist Ophthalmologist Recommendation

11.08.01 Sodium Hyaluronate 0.2% PF Multi Hylo-Forte®

On Specialist Ophthalmologist Recommendation

11.08.01 Sodium Hyaluronate 0.2% Preservative Free Evolve HA®

Approved onto the formulary January 2019

Specialist Ophthalmologist Recommendation

11.08.01 Sodium Hyaluronate 0.4% SDU Clinitas ®

On Specialist Ophthalmologist Recommendation

Single use restricted to patients needing preservative free 

Each unit is re-sealable and may be used for up to 12 hours

02.05.01 Sodium nitroprusside 

Injection (Secondary Care only)

01.06 Sodium Picosulfate 
21 Sodium Picosulfate 
  •  Palliative care use only

 

05.05 Sodium Stibogluconate Pentostam®
02.13 Sodium Tetradecyl Sulphate Fibro-Vein®
04.08.01 Sodium Valproate 

E/C tablets

M/R tablets

Crushable tablets

SF liquid

M/R granules see Episenta®

On specialist advice

 Use in men and women of non-child bearing potential

 Use in women and girls of childbearing potential (all indications).

Contraindicated in women of childbearing potential unless part of the Pregnancy Prevention Programme. See MHRA guidance

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particular manufacturer’s product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

04.08.01 Sodium valproate prolonged release Episenta®

Paediatrician initiation for patients with epilepsy aged up to and including 16 years of age unable to swallow tablets and who require a modified release formulation in whom other formulations are more expensive or not appropriate

Contraindicated in women of childbearing potential unless part of the Pregnancy Prevention Programme. See MHRA guidance

MHRA Advice
Care should be taken when switching between oral formulations. The need for continued supply of a particular manufacturer’s product should be based on clinical judgement and consultation with patient and/or carer, taking into account factors such as seizure frequency and treatment history

09.02.01.01 Sodium zirconium cyclosilicate Lokelma®

In line with NICE

In emergency care for acute life-threatening hyperkalaemia alongside standard care

Grey For people with persistent hyperkalaemia and chronic kidney disease stage 3b to 5 or heart failure, pending publication of RICaD

05.03.03.02 Sofosbuvir Sovaldi®
05.03.03.02 Sofosbuvir/velpatasvir Epclusa®

 

In line with NICE

05.03.03.02 Sofosbuvir/Velpatasvir/Voxilaprevir Vosevi®

In line with NICE

19.03 Softpore® self adhesive  Type of wound product is suitable for
Low to moderately exuding wounds, superficial wounds (closed), light amounts of
exudate.
Use alone without other products, also can be used as a protective dressing for sutured
post operative wounds. Can be used as a protective dressing for newly epithelialised wounds. Can be used for minor traumatic wounds
Duration dressing remains on wound before changing
Maximum 7 days, dependent on exudate levels
Frequency of dressing change
If daily change is required; review dressing type
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity
Rationale for inclusion in formulary
Sutured/Post-surgical wound for protection . Most cost effective option.
Can be used as a protective dressing for newly epithelialized wounds. Can be used for minor traumatic wounds
A5.01.02 Softpore® self adhesive 

Preferred local option

Type of wound product is suitable for
Low to moderately exuding wounds, superficial wounds (closed), light amounts of
exudate.
Use alone without other products, also can be used as a protective dressing for sutured
post operative wounds. Can be used as a protective dressing for newly epithelialised wounds. Can be used for minor traumatic wounds

Duration dressing remains on wound before changing
Maximum 7 days, dependent on exudate levels

Frequency of dressing change
If daily change is required; review dressing type

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity

Rationale for inclusion in formulary
Sutured/Post-surgical wound for protection . Most cost effective option.
Can be used as a protective dressing for newly epithelialized wounds. Can be used for minor traumatic wounds

07.04.02 Solifenacin 
04.04 Solriamfetol Sunosi®

In line with NICE

06.05.01 Somatropin 

 

Genotropin GoQuick powder/solvent for
Genotropin MiniQuick powder/solvent for injection
Genotropin powder/solvent for injection
Humatrope powder/solvent for injection
Norditropin FlexPro
Norditropin NordiFlex
Norditropin SimpleXx
NutropinAq
Omnitrope
Omnitrope SurePal
Saizen
Saizen powder/solvent for injection
Zomacton powder/solvent for injection
08.01.05 Sorafenib Nexavar®

Funding may be available from cancer drugs fund

19.17 Sorbsan ® Packing   Moderate to heavilty exuding cavity wounds. Pack only 80% of the cavity to allow for dressing to swell and leave 2.5cm tail of dressing exposed to facilitate removal.
19.17 Sorbsan ® Plus Border  Shower proof with adhesive border.

Indications: sloughy, granulating wounds, moderate to heavy exudate. Forms a gel which provides a “moist wound environment”, encouraging autolytic debridement and facilitating wound healing. All dressing residue must be irrigated away to avoid an inflammatory response. Do NOT use on dry, lightly exuding or dry necrotic wounds. Have limited lateral absorbency, hence do not need to be cut to shape.
19.17 Sorbsan ® Ribbon  Moderate to heavily exuding cavity wounds. Pack only 80% of the cavity to allow for dressing to swell and leave 2.5cm tailof dressing exposed to facilitate removal.
19.17 Sorbsan® Flat  Can be multilayered if needed.

Indications: sloughy, granulating wounds, moderate to heavy exudate. Forms a gel which provides a “moist wound environment”, encouraging autolytic debridement and facilitating wound healing. All dressing residue must be irrigated away to avoid an inflammatory response. Do NOT use on dry, lightly exuding or dry necrotic wounds. Have limited lateral absorbency, hence do not need to be cut to shape.
19.17 Sorbsan®Plus   Highly absorbent.

Indications: sloughy, granulating wounds, moderate to heavy exudate. Forms a gel which provides a “moist wound environment”, encouraging autolytic debridement and facilitating wound healing. All dressing residue must be irrigated away to avoid an inflammatory response. Do NOT use on dry, lightly exuding or dry necrotic wounds. Have limited lateral absorbency, hence do not need to be cut to shape.
A5.02.06 Sorbsan® range 

Preferred local option

Calcium alginate dressing

Type of wound product is suitable for
Use in moderate to highly exuding wounds with a sloughy or granulating wound bed. Also helps with haemostasis in wounds with minor bleeding or where blood is present in the exudate.
Available in flat and rope dressing
Primary dressing only. Secondary dressing will be required.

Duration dressing remains on wound before changing
Can be left in place for approximately 4 days

Frequency of dressing change
1-4 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use in individuals with a known sensitivity to any of the components of the dressing
Do no use on dry or lightly exuding wounds as adherence is an issue
Extreme caution if used for tumours with friable tissue

Rationale for inclusion in formulary</>
Sorbsan® can facilitate debridement, absorb exudate and is a haemostat
Cost effective
Biodegradable

02.04 Sotalol 

Anti-arrhythmic

 

08.01.05 Sotorasib Lumykras®

In line with NICE

05.02.05 Sotrovimab 
07.03.03 Spermicidal Contraceptives Gygel®2% Gel
05.05 Spiramycin 

Unlicensed

13.11.01 Spiriclens 

Hospital only

02.02.03 Spironolactone 
09.04.01 Spreads 

Low-protein foods

These products are not available to purchase in supermarkets

They are important to provide essential energy and variety to aid the palatability of low protein diets. They are important for good metabolic control of the patient. Poor access to these products could lead to poor dietary adherence. This will cause poor metabolic control which may lead to irreversible brain damage

The NSPKU guidelines for prescription of low protein foods can be used for other amino acid disorderssuch as MSUD, homocystinuria, tyrosinaemia and pyridoxine response epilepsy

Protein free - necessary for children and adults with inborn errors of protein metabolism who do not tolerate very little natural protein

The specialist dietician will make individual reccomendations based on diagnosis,protein recommendations, weight etc.

  • Important protein-free foods to provide important energy, assist dietary adherence and provide variety when natural protein tolerance is very limited. Necessary for children and adults with inborn errors of protein metabolism who tolerate very little natural protein. 1 portion ordinary spread likely to provide 2-5g protein
01.04 St Mark’s powder & solution (unlicensed) 

UNLICENSED

Specialist use only

01.04 St Mark's recipe 

For fluid and electrolye replacement following diarrhoea

Click here for St Mark's recipe

03.01.05 Standard range peak flow meter 

BRANDS

  • Easy Peak Flow Meter
  • Rossmax Peak Flow Meter
04.08.01 Stiripentol Diacomit®

Severe myoclonic epilepsy of infancy (Dravet syndrome)
APC supports use in Adults: for continuation of therapy started in childhood. (Note Off Label use in adults)

02.10 Streptokinase 

Hospial only

05.01.09 Streptomycin Sulphate 
06.06.02 Strontium ranelate  
01.03.03 Sucralfate Tablet 1g. Suspension 500mg/5ml

For specialist initiation only

09.05.02.02 Sucroferric oxyhydroxide Velphoro®

2nd or 3rd line for those intolerant to Sevelamer

Specialist use only

A5.15 Sudocrem 

Barrier cream
Type of wound product is suitable for
Intact skin, not to be applied to a wound.
To protect the skin from moisture, irritation and chafing. To protect the peri wound when utilising free range larvae
Frequency of use
Application at every episode of hygiene. Apply a thin layer sparingly. Remove with olive oil.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used in conjunction with containment products for incontinence due to the inclusion of lanolin in the ingredients, which will repel urine/faeces back onto the skin. Any allergy to the listed ingredients
Rationale for inclusion in formulary
Dermatology approved

13.02.02 Sudocrem® 

Use for areas around stoma, bedsores and pressure areas where the skin is intact

Avoid use with continence pads

Over the counter preparation suitable for self-care/purchase if appropriate

15.01.06 Sugammadex Bridion®

Hospital only

05.04.07 Sulfadiazine 
05.05 Sulfadiazine 
01.05.01 Sulfasalazine 

Plain tablets are more cost effective than enteric coated tablets

Walsall

Green Green -Walsall only

Sandwell 

Amber Recommended Amber Recommended -Sandwell only

Wolverhampton

Amber SC Amber SC-Wolverhampton only

ESCA Sulfasalazine-Wolverhampton only

Dudley 

Amber SC Amber SC-Dudley only

ESCA Sulfasalazine (Dudley only)

10.01.03 Sulfasalazine EC 

Supported by an ESCA

10.01.01 Sulindac  For hospital use only in Polyhydramnios (women only)
04.02.01 Sulpiride 

Supported by ESCA

04.07.04.01 Sumatriptan 

Tablets (prescribe as generic)

Nasal spray £££££

Injection £££££

08.01.05 Sunitinib Sutent®

Commissioned by NHS England in line with NICE

13.08.01 Sunsense® Ultra lotion (SPF 50) 

Non-formulary if not for ACBS approved indication

09.03 Supplementary Preparations Addiphos® For hospital use only
09.03 Supplementary Preparations Additrace® For hospital use only
09.03 Supplementary Preparations Peditrace® For hospital use only
09.03 Supplementary Preparations Solivito N® For hospital use only
09.03 Supplementary Preparations Vitlipid N® For hospital use only
A5.03.04 Suprasorb® X+PHMB 

Hospital use only


Biocellulose gel sheet dressing with PHMB antimicrobial properties
Type of wound product is suitable for
Light to moderately, critically colonised or infected exuding wounds
Can be used on all wound types at all stages of wound healing
Can be cut or folded to wound shape size
Duration dressing remains on wound before changing
1-3 days
Frequency of dressing change
1-3 days, dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to PHMB or any components of the dressing
Heavily exuding wounds
Rationale for inclusion in formulary
Light to moderate exudate in clinically infected wounds.
Suitable for all wounds at all stages of wound healing
Doesn’t affect healthy cells, suitable for long term use when necessary

A5.02.03 Surprasorb X 

Specialist recommendation only
Bio-cellulose gel sheet dressing
Type of wound product is suitable for
Light to moderately, non infected exuding wounds
Duration dressing remains on wound before changing
1-7 days
Frequency of dressing change
1-7 days, dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to any components of the dressing
Rationale for inclusion in formulary
Light to moderate exudate.

15.01.05 Suxamethonium Chloride Anectine®

Hospital only

04.13 Tacrolimus 

Specialist use only for neurological conditions

08.02.02 Tacrolimus AdoPORT®
08.02.02 Tacrolimus Prograf®

Prescribe by brand name only to minimise the risk of inadvertent switching between products, which has been associated with reports of toxicity and graft rejection (June 2012)

Commissioned by NHSE for post transplant patients

Prescribing to remain with the specialist for this patient group

Prograf ®: immediate release/standard release capsule, twice daily dosage

Red Traffic Light  Post transplant- if prescribing is NOT established with GP before 1st April 2013


  Post transplant - if prescribing IS established with GP before 1st April 2013

08.02.02 Tacrolimus Modigraf®

Prescribe by brand only to minimise the risk of inadvertent switching between products, which has been associated with reports of toxicity and graft rejection (June 2012)

Commissioned by NHSE for post transplant patients

Prescribing to remain with the specialist for this patient group

Modigraf®: immediate release formulation, twice daily dosage

Red Traffic Light  Post transplant- if prescribing is NOT established with GP before 1st April 2013


  Post transplant - if prescribing IS established with GP before 1st April 2013

08.02.02 Tacrolimus Advagraf ®

Prescribe by brand name only to minimise the risk of inadvertent switching between products, which has been associated with reports of toxicity and graft rejection (June 2012)

Commissioned by NHSE for post transplant patients

Prescribing to remain with the specialist for this patient group

Advagraf ®: prolonged release capsule, once daily dosage

Red Traffic Light  Post transplant- if prescribing is NOT established with GP before 1st April 2013


  Post transplant - if prescribing IS established with GP before 1st April 2013

13.05.03 Tacrolimus Protopic®

Dot Initiated by hospital only
Dot In line with NICE
Dot 0.03%
Dot 0.1%

13.14.07 Tacrolimus 0.1% w/w in Orabase® 
13.14.07 Tacrolimus 0.3% w/w in Orabase® 
07.04.05 Tadalafil 

More cost effective options available

Erectile Dysfunction Only

On demand preparation only


SLS criteria still apply

Quanties in line with HSC Guidance


Maxiumum 4 tablets per month (NOT DAILY)

Black for Lower Urinary tract symptoms in Benign Prostatic Hyperplasia

11.06 Tafluprost  

2nd line PF option

On Specialist Ophthalmologist Recommendation

08.01.05 Talimogene Iaherparepvec Imlygic®

Hospital ONLY - NHS England commissioned

In line with NICE and available from day 91 following publication of TA

06.07 TAMOXIFEN 

 

  • TABLETS
  • ORAL SOLUTION
08.03.04.01 Tamoxifen 
07.04.01 Tamsulosin 

Reduce BP - care with other antihypertensives
Caution in elderly
Care with hepatic and severe renal impairment
Contraindicated in postural hypotension or micturition syncope

04.07.02 Tapentadol Palexia®
13.05.02 Tars - bath preparations Psoriderm® emulsion
02.08 TauroLock TauroLock HEP 500®
05.01 Tedizolid Oral and IV
A5.02.05 Tegaderm Foam Adhesive 

Type of wound product is suitable for
Wound management by secondary intention on acute, chronic, full thickness or partial thickness or shallow granulating wounds including pressure ulcers, leg ulcers, diabetic foot ulcers, malignant wounds, surgical wounds, donor sites and fungating ulcers
Can be used as a primary or secondary dressing
Film border increases adherence
Duration dressing remains on wound before changing
Can stay in place up to 3-7 days
Frequency of dressing change
Dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Care with fragile skin
Rationale for inclusion in formulary
Can be used for low to moderate exudate levels
Different sizes and shapes available
Conformability around difficult areas such as heels and elbows
Can be used on sacral and buttock wounds where incontinence is an issue due to film backing and border.

19.10 Tegaderm® Film   Indications: shallow, lightly exuding wounds, adhesive primary or secondary dressing. Properties include: provide protection from exposure to friction, maintain moisture to prevent scab formation, vapour permeable to water and oxygen but impermeable to micro-organisms, for use when occlusion is required. Allow 4cm skin overlap when applying dressing, stretch film parallel to skin to release adhesives and prevent trauma to skin on removal.
NOT suitable for infected wounds Caution: exudate may accumulate under the dressing which can lead to tissue maceration,
19.16 Tegadern Foam Adhesive  Indications: granulating, epithelialising or wounds with minimal slough and moderate exudate (of limited value in dry/necrotic wounds). Primary or secondary dressing which should overlap wound edge by 2-3cm. ‘Erythematous reaction’ (redness in the shape of the dressing) may be observed when dressing is removed due to increased blood flow following thermal insulation, or lateral wicking of exudate to peri-wound skin.
05.01.07 Teicoplanin 

For hospital use only

05.01 Telavancin 
19.03 Telfa®  PODIATRY USE ONLY
Thin absorbent cotton pad with non adherent film
Type of wound product is suitable for
Dry or lightly exuding wounds
Duration dressing remains on wound before changing
1-7 days
Frequency of dressing change
As exudate levels determine
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None
Rationale for inclusion in formulary
Cost effective. Non adherent dressing for dry or lightly exuding wounds
A5.01.02 Telfa® 

PODIATRY USE ONLY

Thin absorbent cotton pad with non adherent film

Type of wound product is suitable for
Dry or lightly exuding wounds

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
As exudate levels determine

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None

Rationale for inclusion in formulary
Cost effective. Non adherent dressing for dry or lightly exuding wounds

04.01.01 Temazepam 

From Monday 1st June 2015, prescriptions for temazepam will be required to meet full prescription requirements for Schedule 3 controlled drugs (CDs)

Legislative changes to prescription writing requirements for temazepam

04.01.01 Temazepam 

£££££

From Monday 1st June 2015, prescriptions for temazepam will be required to meet full prescription requirements for Schedule 3 controlled drugs (CDs)

Legislative changes to prescription writing requirements for temazepam

15.01.04.01 Temazepam 

Hospital only

05.01.01.02 Temocillin Negaban®
05.01.01.02 Temocillin 
08.01.05 Temozolomide Temodal®
08.01.05 Temsirolimus Torisel®

Hospital only

02.11 Tenecteplase 

Hospital only

05.03.03.01 Tenofovir alafenamide Vemlidy®
05.03.03.01 Tenofovir Disproxil  
05.03.01 Tenofovir, cobicistat, elvitegravir & emtricitabine Stribild®
15.01.04.02 Tenoxicam 

Hospital only

09.04.02 Tentrini®  
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • Polymeric feed, used in children 20-45kg as tube feed, no added fibre
  • Also essential low protein tube feeds for teenagers with inborn errors of protein metabolism (e.g. organic acidaemias, urea cycle disorders) due to its protein profile. It provides a natural protein source. It is used when IMD teenagers cannot tolerate fibre. To change to an alternative enteral feed with teenagers with metabolic disorders would potentially require hospital admission to ensure stabilisation with a new enteral feed. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient.
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure in child 7–12 years, body-weight 21–45 kg
09.04.02 Tentrini® Energy 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml tube feed for children 20-45kg
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula and growth failure, in child 7–12 years, body-weight 21–45 kg
09.04.02 Tentrini® Energy Multi Fibre 
  • Child: 1.5 kcal/mL and more than 4g protein/100 mL
  • 1.5kcal/ml tube feed for children 20-45kg with added fibre
  • Paediatric ACBS indications: Disease-related malnutrition, intractable malabsorption, growth failure, pre-operative preparation of malnourished patients, dysphagia, short-bowel syndrome, bowel fistula and proven inflammatory bowel disease, in child 7–12 years, body-weight 21–45 kg
09.04.02 Tentrini® Multi Fibre 
  • Child: 1 kcal/ml and less than 4g protein/100ml
  • Polymeric feed, used in children 20-45kg as tube feed, added fibre
  • Also essential in low protein tube feeds for teenagers with inborn errors of protein metabolism (e.g. organic acidaemias, urea cycle disorders) due to its protein profile. It provides a natural protein source. It is used when IMD teenagers cannot tolerate fibre. To change to an alternative enteral feed with teenagers with metabolic disorders would potentially require hospital admission to ensure stabilisation with new enteral feed. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula except bowel fistula, and growth failure in child 7–12 years body-weight 21–45 kg
08.01.05 Tepotinib Tepmetko®

In line with NICE

05.02 Terbinafine 
13.10.02 Terbinafine 1% cream 

First line for dermatophyte skin infection.

03.01.01.01 Terbutaline Bricanyl®

How to use a Turbohaler Inhaler

03.01.01.01 Terbutaline 

How to use a Turbohaler Inhaler

07.01.03 Terbutaline  For Specialist/ Hospital Use Only
08.02.04 Teriflunomide Aubagio®

In line with NICE

Commissioned by NHSE for multiple sclerosis

06.06 Teriparatide 

Red - Forsteo

Red - Movymia

Red - Terrosa

01.09 Terlipressin Glypressin®
06.05 TERLIPRESSIN 

Glypressin - Red

06.01.06 Test strips 

   BRANDS

  • Aviva testing strips
  • FreeStyle Optium testing strips
  • On Call Extra testing strips
06.01.06 Test strips 

  BRANDS-Use in line with local guidance

  • CareSens PRO testing strips
  • Contour Next testing strips
  • Contour Plus testing strips
  • Instant testing strips
  • TEE2 testing strips
  • WaveSense JAZZ Duo testing strips
  • WaveSense JAZZ testing strips
06.04.02 Testosterone  Sustanon 250®
06.04.02 Testosterone gel 
06.04.02 Testosterone Propionate 
06.04.02 Testosterone undecanoate Nebido®
14.05.02 Tetanus immunoglobulin 
04.09.03 Tetrabenazine 

Tablets

15.02 Tetracaine (Amethocaine) 4% Ametop®

First line at Birmingham Children's Hospital

06.05 TETRACOSACTIDE 

   BRANDS

  • Synacthen
  • Synacthen Depot
05.01.03 Tetracycline 

Specialist Advice for H. pylori relapse only

05.01.10 Thalidomide oral presentations
08.02.04 Thalidomide 

In line with NICE

Commissioned by NHSE

13.05.03 Thalidomide 

NHSE commissioned

03.01.03 Theophylline Uniphyllin Continus
09.06.02 Thiamine 
15.01.01 Thiopental 

HOSPITAL ONLY

08.01.01 Thiotepa 

Commissioned by NHSE
Hospital only

09.09 Thixo-D® 
  • Intolerance to locust bean gum in children under 1
  • For thickening of foods in dysphagia
  • Not suitable for children under 1 year except in cases of failure to thrive
06.05 THYROTROPIN ALFA Thyrogen®
05.05 Tiabendazole 500mg tabs 
06.04 Tibolone Livial®
02.09 Ticagrelor Brilique®
05.01.03 Tigecycline 
13.05.03 Tildrakizumab Ilumya®

In line with NICE

13.04 Timodine® 

Potency-mild

Use for short periods - typically no more than one week

11.06 Timolol 

On Specialist Ophthalmologist Recommendation

11.06 Timolol LA 

On Specialist Ophthalmologist Recommendation

Once daily preparation

11.06 Timolol Unit Dose Tiopex ®

On Specialist Ophthalmologist Recommendation

Once daily preparation

05.05 Tinidazole 
02.08.01 Tinzaparin 

Use current Place/Trust status and local guidelines

Sandwell

Green Single use in suspected DVT

Red For all other indications

The APC's view is that on clinical grounds, the status for certain indications approved by APC should be Amber Shared Care, supported by an ESCA. These indications are:

  • Deep vein thrombosis (including paediatrics)
  • Pulmonary embolism (including paediatrics)
  • Intolerance/unsuitable for oral anticoagulants
  • Certain cancer patients
  • Injectable drug users
  • Pregnant women
    HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED (ESCAs to be developed). This should not prevent individuals in primary care providing initial prescriptions in urgent situations e.g. pregnancy where there is a high thrombotic risk.

 

Wolverhampton

Amber Initiation

Walsall

Black 

Dudley

Red

08.01.03 Tioguanine 

Commissioned by NHSE

03.01.02 Tiotropium Spiriva Respimat®

How to use a Respimat Inhaler

03.01.04 Tiotropium & Olodaterol Spiolto® Respimat®



How to use a Respimat Inhaler

02.06 Tirofiban Aggrastat®
02.09 Tirofiban Aggrastat®
08.01.05 Tisagenlecleucel Kymriah®

In line with NICE

Providers - NHS hospital trusts

02.11 Tisseel® 
08.01.05 Tivozanib Fotivda®

In line with NICE

10.02.02 Tizanidine 
03.13 Tobramycin 

 

 

05.01.04 Tobramycin  Munuza ®
05.01.04 Tobramycin Bramitob®
05.01.04 Tobramycin  Tymbrineb ®
05.01.04 Tobramycin  Vantobra ®
05.01.04 Tobramycin  TOBI Podhaler®

For specialist prescribing only


05.01.04 Tobramycin 
10.01.03 Tocilizumab RoActemra®

Hospital use only

In line with NICE

Paediatric use is commissioned by NHSE

01.05.03 Tofacitinib Xeljanz®

In line with NICE

Tofacitinib for moderately to severe active ulcerative colitis - providers are NHS hospital trusts

06.01.02.01 Tolbutamide 
07.04.02 Tolterodine 
07.04.02 Tolterodine 

Normal release tablets more cost effective.

06.05.02 Tolvaptan Samsca®

 

06.05.02 Tolvaptan Jinarc®

  

A5.06.01 Topical Negative Pressure Therapy 

Specialist recommendation only
The use of sub atmospheric pressure to promote or assist wound healing or to remove fluids from a site. Required components: Pump, dressings foam or gauze, tubing and canister.
Type of wound product is suitable for
Acute, chronic and traumatic wounds. Can be used as a adjunct to surgery and for
salvage procedures such as wound dehiscence. Benefits are that it removes excess fluid that may contain bacterial pathogens, reduces soft tissue oedema, promotes granulation and provides a moist wound healing environment.
Consider standard interactive dressings first.
Duration dressing remains on wound before changing
Every three days
Frequency of dressing change
Determined by exudate levels. Different canister sizes available
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
It should not be used on: Grossly infected or bleeding wounds
Malignancy
Exposed blood vessels
Organs
Unexplored fistulae
Extensive necrotic wounds
Caution with foam, document the number inserted, ensure all pieces are retrieved.
Rationale for inclusion in formulary
It removes excess fluid that may contain bacterial pathogens, reduces soft tissue
oedema, promotes granulation and provides a moist wound healing environment. Both companies products are included due to different contracting arrangements. Can be used on large open wounds to increase speed of wound healing

04.07.04.02 Topiramate 

For migraine prophylaxis as per guidance

On specialist recommendation

04.08.01 Topiramate 

On specialist advice

MHRA Advice
MHRA advises that when prescribing for epilepsy the patient should be assessed to make a clinical judgement if the same manufacturer's product/brand is necessary taking into account factors such as seizure frequency and treatment history. Also take into account patient/carer related factors such as their negative perceptions about alternative products and/or other issues related to the patient such as co-morbid autism, mental health issues or learning disability

08.01.05 Topotecan Hyxamtin®

In line with NICE

Commissioned by NHSE

Hospital only 

04.07.02 Tramadol 

Third line after morphine and codeine

Please note modified release preparations are non-formulary

04.07.02 Tramadol 

Third line after morphine and codeine

Only for patients with swallowing difficulties

Capsules more cost effective

15.01.04.03 Tramadol 

Hospital only

02.11 Tranexamic Acid 
02.11 Tranexamic Acid 

Palliative use only

21 Tranexamic acid  
  •  The risk of bleeding can be affected by other factors such as the presence of fungating or infected wounds. Smaller bleeds can be palliated using topical tranexamic acid.
02.11 Tranexamic acid 5% mouthwash 
02.11 Tranexamic Acid Injection 

Injection (Secondary Care only)

12.03.04 Tranexamic Acid Mouthwash 

Hospital use only

08.01.05 Trastuzumab Herceptin®

Funding may be available from cancer drug fund

Hospital only  

In line with NICE

08.01.05 Trastuzumab Enhertu®

Hospital Trust use only

Use in line with NICE

08.01.05 Trastuzumab emtansine Kadcyla®

In line with NICE

04.03.01 Trazodone 

Tablets

Capsules

SF Liquid

03.04 Tree pollen extract Pollinex Trees ®
03.04 Tree pollen extract Pollinex trees ®
08.01.01 Treosulfan 

In line with NICE

Commissioned by NHSE
Injection-hospital only

10.01.02.02 Triamcinolone Acetonide 
13.14.07 Triamcinolone acetonide 0.1% w/w in Orabase® 
13.14.07 Trichloroacetic acid 90% w/v 
06.04.01.01 Tridestra®  
09.08.01 Trientine Dihydrochloride 

For specialist initiation only.
For use in Wilson's disease in patients intolerant of penicillamine.

04.02.01 Trifluoperazine 

Dot tablets
Dot SF solution
Dot Supported by ESCA

11.03.03 Trifluorothymidine  
08.01.03 Trifluridine-tipiracil Lonsurf®

£££££

In line with NICE

Hospital only

NHSE commissioned

04.02.03 Trihexyphenidyl 
04.09.02 Trihexyphenidyl 

Tablets

05.01.08 Trimethoprim 
05.01.08 Trimethoprim 
05.01.13 Trimethoprim 

Second choice in UTI

13.06.02 Trimethoprim 

Off label use-specialist initiation.

13.04 Trimovate® 

Potency: moderate

Restricted to use in inflammatory conditions associated with an infection with confirmed susceptibility to the antimicrobial component

Use for short periods - typically no more than one week

06.07 TRIPTORELIN 
06.07 TRIPTORELIN 
06.07.02 Triptorelin Decapeptyl SR®
06.07.02 Triptorelin Salvacyl®
08.03.04.02 Triptorelin Decapeptyl® SR

Accepted on formulary January 2017 following new drug application

Cost-effective alternative to current formulary options and a longer administration interval

06.04 Trisequens ® 
09.08.02 Trometamol 7%  NHSE commissioned
11.05 Tropicamide Mydriacyl®

Hospital only

11.05 Tropicamide Single Use Minims® Tropicamide

Hospital only

07.04.02 Trospium Regurin® XL

For patients over 65 years of age

07.04.02 Trospium 

For patients over 65 years old

04.03.04 Tryptophan  Hospital use only
A5.08.03 Tubegauz® 

PODIATRY USE ONLY-NOT PRESCRIBABLE ON NHS Not NHS
Surgical stockinette 100% cotton

Type of wound product is suitable for
PODIATRY ONLY for digital dressings

Duration dressing remains on wound before changing
As required

Frequency of dressing change
As required

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
None listed

Rationale for inclusion in formulary
Only product that has finger and toe sizes in 100% cotton

14.04 Tuberculin PPD injection
08.01.05 Tucatinib Tukysa®

In line with NICE

14.04 Typhoid and Hepatitis A ViATIM®
14.04 Typhoid Live Oral vaccine Vivotif®
09.04 TYR Anamix® Infant 
  • A supplement without tyrosine and phenylalanine for infants with tyrosinaemia
  • The only infant amino acid supplement without tyrosine and phenylalanine for infants with tyrosinaemia
  • Nutritional supplement for the dietary management of proven tyrosinaemia where plasma-methionine concentrations are normal in children from birth to 3 years
09.04 TYR Anamix® Junior 
  • A supplement without tyrosine and phenylalanine for children with tyrosinaemia
  • An unthickened powdered amino acid supplement without tyrosine and phenylalanine for children aged 1 to 10y with tyrosinaemia
  • Nutritional supplement for the dietary management of proven tyrosinaemia in children 1–10 years
09.04 TYR Anamix® Junior LQ 
  • A supplement without tyrosine and phenylalanine for children with tyrosinaemia
  • A liquid amino acid supplement without tyrosine and phenylalanine for children aged 1 to 10y with tyrosinaemia. Ready to use. Can be delivered via a tube
  • Nutritional supplement for the dietary management of tyrosinaemia type 1 (when nitisinone (NTBC) is used, see "nitisinone"), type II, and type III, in children over 1 year
09.04 TYR cooler® 10 
  • A supplement without tyrosine and phenylalanine for children and adults with tyrosinaemia
  • An oral liquid amino acid supplement without tyrosine and phenylalanine formulated for children aged 3 to 6 years with tyrosinaemia. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements. The 2 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of tyrosinaemia in children over 3 years and adults
09.04 TYR cooler® 15 
  • A supplement without tyrosine and phenylalanine for teenagers and adults with tyrosinaemia
  • One of two oral liquid amino acid supplements without tyrosine and phenylalanine for children aged 7 to 12 years with tyrosinaemia. Larger pouches are unacceptable for this age group of children and provide in excess of protein requirements
  • Nutritional supplement for the dietary management of tyrosinaemia in children over 3 years and adults
09.04 TYR cooler® 20 
  • A supplement without tyrosine and phenylalanine for teenagers and adults with tyrosinaemia
  • One of 2 liquid amino acid supplements without tyrosine and phenylalanine for teenagers and adults (>12 years of age) with tyrosinaemia that will meet their higher amino acid requirements. This age group needs the larger sachets (20g protein equivalent) to meet their non-tyrosine/phenylalanine protein requirements. It is important we have a choice of more than 1 product for this age group as compliance is poor. The 2 different products have a different degree of sweetness and range of flavours
09.04 TYR express15® 
  • A supplement without tyrosine and phenylalanine for teenagers and adults with tyrosinaemia
  • The only powdered amino acid supplement without tyrosine and phenylalanine for 7 to 12-year olds with tyrosinaemia. Larger sachets are unacceptable for this age group of children and provide in excess of protein requirements
  • Nutritional supplement for the dietary management of tyrosinaemia in children over 8 years and adults
09.04 TYR express20® 
  • A supplement without tyrosine and phenylalanine for teenagers and adults with tyrosinaemia
  • One of 2 powdered amino acid supplements without tyrosine phenylalanine for teenagers and adults with phenylketonuria that will meet their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-tyrosine/phenylalanine protein requirements. It is important we have a choice of more than 1 product for this age group as compliance is poor. The 2 different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of tyrosinaemia in children over 8 years
09.04 TYR Gel® 
  • A supplement without tyrosine and phenylalanine for teenagers with tyrosinaemia
  • The only weaning (thickened) amino acid supplement without tyrosine and phenylalanine for infants/young children with tyrosinaemia
  • Nutritional supplement for the dietary management of tyrosinaemia in children 1–10 years
09.04 TYR Lophlex® LQ 20 
  • A supplement without tyrosine and phenylalanine for teenagers with tyrosinaemia
  • One of 2 liquid amino acid supplements without tyrosine and phenylalanine for teenagers and adults (>12 years of age) with tyrosinaemia that will meet their higher amino acid requirements. This age group need the larger sachets (20g protein equivalent) to meet their non-tyrosine/phenylalanine protein requirements. It is important we have a choice of more than 1 product for this age group as compliance is reported to be poor. different products have a different degree of sweetness and range of flavours
  • Nutritional supplement for the dietary management of tyrosinaemia in children over 3 years and adults
09.04 UCD Amino5 
  • Essential amino acid supplement for use in urea cycle disorders
  • Essential amino acid supplement for use in urea cycle disorders and the cerebral creatine deficiency syndrome: guanidinoacetate methyltransferase (GAMT) deficiency. The only pre-measured sachet of essential amino acids without vitamins and minerals (designed for tube feeding) for the treatment of urea cycle disorders. This is particularly important as most of our families with urea cycle disorders do not speak English as their first language so require pre-measured products. Unmeasured use of essential amino acid supplements in UCD could lead to hyperammonaemia, acute brain encephalopathy and ITU admission. The dose and frequency of administration will be determined by the specialist dietitian
A5.05.03 UCS® Debridement  

Single use pre- moistened cloth for wound debridement.  Can be used to remove hyperkeratosis.


Type of wound product is suitable for

All acute and chronic wounds including pressure ulcers, leg ulcers, diabetic foot ulcers.

Hyperkeratosis


Duration dressing remains on wound before changing
Not applicable


Frequency of dressing change
At each dressing change or as required


Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Heavy slough and necrotic tissue may require autolytic debridement to soften prior to use
Thick hyperkeratosis may take more than one treatment


Rationale for inclusion in formulary
Lifts wound debris, superficial slough and exudate, without inhibiting granulation tissue formation
Compatible with subsequent use of any type of dressing.
Lifts hyperkeratosis and dry flaking skin to peri-wound
Convenient, pre- moistened,  easy to use, disposable single use cloth

07.03.05 Ulipristal EllaOne®

Can be used up to 5 days post-coitus
For use where copper IUD not preferred/tolerated

03.01.02 Umeclidinium Incruse® Ellipta®



How to use an Ellipta Inhaler

03.01.04 Umeclidinium & vilanterol Anoro Ellipta®



How to use an Ellipta Inhaler

01.07.02 Uniroid HC® 

Contains the same ingredients as Proctosedyl® but is much more cost effective

10.01.03 Upadacitinib Rinvoq®

In line with NICE

Providers are NHS Hospital Trusts

01.03 Urea  
A5.08.08 Urgo K4 range® 

Preferred local option

Multi layer compression system

Type of wound product is suitable for
Venous and mixed aetiology leg ulcers and associated conditions

Duration dressing remains on wound before changing
1 to 7 days

Frequency of dressing change
Daily up to weekly dependant on exudate and oedema management.

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not recommended for patients with a ABPI of less than 0.8
Contains latex
Kit size determined by measuring the ankle after padding with the tape measure pulled
taught

Rationale for inclusion in formulary
Compression system consisting of K-Soft , K-Lite, K-Plus or K-ThreeC (dependent on ankle size) and Ko-Flex
Component bandages available in longer lengths for larger limbs

A5.02.04 UrgoClean® Dressings 

Type of wound product is suitable for

All non-infected sloughy wounds including diabetic foot ulcers, burns, leg and pressure ulcers

Duration dressing remains on wound before changing

UrgoClean Pad should be changed every 1 to 2 days during the wound desloughing phase, then as often as required (up to 7 days) depending on the level of exudate and the clinical condition of the wound

Frequency of dressing change

Can be left in place for up to 7 days 

Caution/Contraindiciations (when not to use the dressing, patient groups to avoid etc.)

Do not use if there is a known sensitivity to UrgoClean

Do not use Urgoclean as a surgical sponge for heavily bleeding wounds

Rational for inclusion to formulary

No other comparable dressing available

A5.08.08 UrgoKTwo® 

Two layer bandage system consisting of elastic and inelastic components that provide a sustained graduated compression,.
Also available in UrgoKTwo reduced compression.

Type of wound product is suitable for
Treatment of venous leg ulcers, venous oedema and lymphoedema

Duration dressing remains on wound before changing
1 to 7 days

Frequency of dressing change
Daily up to weekly dependant on exudate and oedema management.

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Arterial disease
Diabetic Microangiplathy
Ischaemic Phlebitis
Septic thrombosis
Allergy to any components in particular latex (available in latex free )

Rationale for inclusion in formulary
Two layer compression kit.
Essential for treating venous leg ulceration
2 layer less bulky for community use and enabling patients to wear foot wear
Available in latex free option and reduced compression option

A5.03.03 UrgoSorb Silver range 

Specialist recommendation only
Alginate and hydrocolloid dressings containing silver
Type of wound product is suitable for
Management of moderate to heavily exuding wounds that are clinically infected. Absorbs and gels on contact with wound exudate which facilitates debridement of devitalised tissue.
Dressing has haemostatic properties
Duration dressing remains on wound before changing
1-3 days dependent on exudate levels
Frequency of dressing change
1-3 days dependent on exudate levels
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to any of the dressing components
Contraindicated in 3rd degree burns, dry necrotic eschar
Low exudate or dry wounds
Removal on those undergoing MRI scans
Avoid contact with electrodes or conductive gels during electronic measurement procedures
Rationale for inclusion in formulary
Can be used for moderate to heavily exuding clinically infected wounds
Can be used for debriding sloughy and wet necrotic wounds
Haemostatic

A5.02.06 UrgoSorb® range 

Specialist recommendation only

Type of wound product is suitable for
Management of moderate to heavily exuding wounds. Absorbs and gels on contact with
wound exudate which facilitates debridement of devitalised tissue. Dressing has haemostatic properties

Duration dressing remains on wound before changing
1-7 days dependent on exudate levels

Frequency of dressing change
1-7 days dependent on exudate levels

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to any of the dressing components Contraindicated in 3rd degree burns, dry necrotic eschar
Low exudate or dry wounds

Rationale for inclusion in formulary
Can be used for moderate to heavily exuding wounds
Can be used for debriding sloughy and wet necrotic wounds
Haemostatic

A5.04.01 UrgoSTART ® Plus Border/UrgoSTART® Plus Pad range 

A polyabsorbent fibre pad containing a protease inhibitor (TLC-NOSF Healing Matrix), polyabsorbent fibres, a superabsorbent layer and a silicone border with waterproof backing. 

Type of wound product is suitable for

All stages (from desloughing to complete healing) of exuding wounds including leg ulcers, diabetic foot ulcers, pressure ulcers, and long-standing acute wounds. 

Duration dressing remains on wound before changing

Up to 7 days (recommended to change dressing every 1-2 days at initiation).

Frequency of dressing change

3-7 days

Wounds with high exudate levels may need changing more frequently and may need a secondary dressing.

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)

Not to be used on infected wounds

Rationale for inclusion in formulary

Cheaper than UrgoStart/UrgoClean combination

Easy to Use

Well tolerated

Positive outcomes on long-standing wounds

A5.02.03 UrgoTul 

A non-adherent flexible wound contact layer containing TLC Healing Matrix.

Type of wound product is suitable for
Non to low exuding wounds, dermabrasions, traumatic, superficial, blistering. Can be
used as a contact layer in cavity wounds with secondary absorbent dressing. Difficult to dress
areas – fingers and toes.

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Depends on clinical needs up to 7 days

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known sensitivity to any components

Rationale for inclusion in formulary
Pain free dressing changes. Promotes healing, interactive. Cost effective. Large range of sizes available

06.01.06 Urinalysis Glucose strips Medi-Test Glucose®  
06.01.06 Urinalysis test strips Diastix® 
06.01.06 Urine Protein strips  Albustix®

Black in Primary Care

Secondary care to discuss with Pathology

06.01.06 Urine Protein strips Medi Test Protein 2® 
02.10 Urokinase 

Hospital only

01.09 Ursodeoxycholic acid 

For specialist initiation only

01.05 Ustekinumab Stelara®

In line with NICE

Hospital use only

13.05.03 Ustekinumab 

Initiated by hospital consultant only and in line with NICE

For treating moderate to severe psoriasis

A5.06.01 V.A.C. products 

Preferred local option
Specialist recommendation only
The use of sub atmospheric pressure to promote or assist wound healing or to remove fluids from a site. Required components: Pump, Dressings foam or gauze, tubing and canister.

Type of wound product is suitable for
Acute, chronic and traumatic wounds. Can be used as a adjunct to surgery and for salvage procedures such as wound dehiscence. Benefits are that it removes excess fluid that may contain bacterial pathogens, reduces soft tissue oedema, promotes granulation and provides a moist wound healing environment. Consider standard interactive dressings first.

Duration dressing remains on wound before changing
Every three days

Frequency of dressing change
Determined by exudate levels. Different canister sizes available

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
It should not be used on:
Grossly infected or bleeding wounds
Malignancy
Exposed blood vessels
Organs
Unexplored fistulae
Extensive necrotic wounds
Caution with foam, document the number inserted, ensure all pieces are retrieved.

Rationale for inclusion in formulary
It removes excess fluid that may contain bacterial pathogens, reduces soft tissue oedema, promotes granulation and provides a moist wound healing environment. Both companies products are included due to different contracting arrangements. Can be used on large open wounds to increase speed of wound healing

07.04.05 Vacuum pumps 


Green Traffic Light  Avaiable in line with SLS criteria


Red Traffic Light  If use not in line with SLS criteria

Use device with lowest acquisition cost

05.03.02.01 Valaciclovir 

To be used in exceptional cases only

Least cost effective option

Second line for shingles if compliance is a problem 

£££££

05.03.02.02 Valganciclovir 
09.04 Valine 1000® 
  • Used as an inpatient only
  • Used at the time of diagnosis when on haemofiltration and a valine supplement is necessary
09.04 Valine50® 
  • To correct valine deficiency in MSUD
  • The only pre-measured sachet of valine that provides 50 mg/dose to correct valine deficiency in MSUD. A pre-measured sachet is particularly important as most of our families with MSUD do not speak English as their first language so require pre-measured products. The dose and frequency of administration will be determined by the specialist dietitian
  • Nutritional supplement for the dietary management of inborn errors of amino acid metabolism in adults and children from birth
04.02.03 Valproic Acid Depakote®

 Use in men and women of non-child bearing potential

 Use in women and girls of childbearing potential (all indications).  ESCA link below

Contrindiciated in women of childbearing potential unless part of the Pregnancy Prevention Programme. See MHRA guidance

02.05.05.02 Valsartan 
05.01.07 Vancomycin 
05.01.07 Vancomycin 
04.10.02 Varenicline Champix®
14.04 Varicella Zoster vaccine Zostavax®
14.05.02 Varicella-Zoster immunoglobulin 
01.09 Vasopressin Pitressin®
06.05 VASOPRESSIN 

Argipressin - Red

Pitressin - Red

01.05.03 Vedolizumab Entyvio®

Specialist use only in line with NICE  guidance below

09.08.01 Velaglucerase alfa Vpriv® NHSE commissioned
08.01.05 Vemurafenib Zelboraf®

In line with NICE

08.01.05 Venetoclax Venclyxto®

In line with NICE

Providers are NHS hospital trusts

04.03.04 Venlafaxine  

1st choice = Vensir XL capsules (suggest switching generic prescriptions to this agent)
2nd choice = Venlalic XL tablets

04.03.04 Venlafaxine 
02.06.02 Verapamil 

Brand prescribe modified release preparations

Follow Optimise Rx advice for new initations


11.08.02 Verteporfin Visudyne®
04.08.01 Vigabatrin 

On specialist advice with an ESCA

08.01.04 Vinblastine Sulphate  Commissioned by NHSE
Hospital only
08.01.04 Vincristine Sulphate  Commissioned by NHSE
Hospital only
08.01.04 Vinorelbine 

Commissioned by NHSE
Injection-hospital only

A5.08.09 Viscopaste 

Preferred local option

Specialist recommendation only

Zinc paste bandage.

Type of wound product is suitable for
Venous leg ulcers. Where venous insufficiency exists, the paste bandage should be used
under graduated compression bandaging. Chronic eczema
Dermatitis

Duration dressing remains on wound before changing
Up to 7 days

Frequency of dressing change
Daily, up to weekly dependant on skin and wound management.

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use in any cases of sensitivity or allergy to ingredients

Rationale for inclusion in formulary
For treatment of dermatitis and chronic eczema when venous insufficiency is present

19.49 Viscopaste PB7®  Zinc Paste Bandage has been used with compression bandaging for the treatment of venous leg ulcers. However, paste bandages are associated with hypersensitivity reactions and should be used with caution.
11.08.01 Viscotears eye drops 
11.08.01 Viscotears Liquid gel single dose units 
09.04.02 Vital 1.5kcal 
  • 200ml size only - for larger volumes use Nutrison Peptisorb Plus HEHP
  • 1.5 kcal/mL and 5g (or more) protein/100 mL
  • Hydrolysate nutritionally complete in 1 litre
  • Standard ACBS indications: Disease-related malnutrition, intractable malabsorption, pre-operative preparation of malnourished patients, dysphagia, proven inflammatory bowel disease, following total gastrectomy, short-bowel syndrome, bowel fistula; except proven inflammatory bowel disease and following total gastrectomy; not recommended for use in children
09.06.01 Vitamin A  Paediatric directorate only
09.06.01 Vitamin A 150,000 units  
09.06.07 Vitamin and mineral supplements Forceval Soluble®and Forceval®

Specialist recommendation
Forceval soluble®-check availability

  • Please prescribe as per Chapter 9
  • Vitamin and mineral deficiency and as adjunct in synthetic diets
09.06.02 Vitamin B Tablets, Compound Strong 

Refeeding Syndrome only

09.06.05 Vitamin E Suspension 100mg/ml 

Specialist recommendation

Alpha tocopheryl acetate oral suspension 100mg/ml

£££££

09.06.01 Vitamins A and D 

Specialist recommendation

09.04 Vitasavoury 
  • Protein, fat, and carbohydrate
  • Taste fatigue to sweet products
  • Disease-related malnutrition, malabsorption states, or other conditions requiring fortification with a high fat or carbohydrate (with protein) supplement
  • Not suitable for child under 3 years
02.12 Volanesorsen  
05.02.01 Voriconazole 
04.03.03 Vortioxetine 

In line with NICE

Specialist initiation and stabilisation before transfer to Primary Care

02.08 Warfarin 

Sandwell place

Process for continuing prescribing oral anticoagulants in Primary care-Sandwell only

03.04.02 Wasp venom extract 
09.02.02.01 Water for injections 
13.02.01 White Soft Paraffin BP 

Most greasy

Over the counter preparation suitable for self-care/purchase if appropriate

09.04 Wysoy® 
  • Specialised formulas: Infant and child: Soya-based formula
  • Essential for galactosaemia. The only completely lactose free formula, soya based formula suitable for these infants, recommended in international galactosaemia guidelines for feeding infants. The dose and type of product should always be advised by the specialist dietitian according to the needs of the patient
  • Proven lactose and associated sucrose intolerance in pre-school children, galactokinase deficiency, galactosaemia, and proven whole cows' milk sensitivity
11.08.01 Xailin gel 
11.08.01 Xailin Night® 


 

A5.05.01 Xupad range 

Preferred local option

Latex free absorbent dressing pad
Type of wound product is suitable for
Low exuding closed surgical wounds only
Duration dressing remains on wound before changing
1 – 7 days depending on exudate
Frequency of dressing change
1 – 7 days depending on exudate
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not for moderate or highly exuding wounds. Always consider an interactive dressing. Not suitable for any wound type except for closed surgical wounds
Rationale for inclusion in formulary
Cost effective
Various sizes available

12.02.02 Xylometazoline 

Short Term Use Only

Do not exceed 7 days treatment. Rebound congestion may occur on withdrawal.

Maximum of 5 days in children aged 6-12 years. Do not use in children under 6 years.

05.03.04 Zanamivir  Relenza®

Green For Primary Care-Green only during Flu season and on authorisation by NHS England/Department of Health & Social Care or via commissioned service for out of season supply

05.03.04 Zanamivir Injection Dectova ®
13.02.01.01 ZeroAQS 

SLS free

Over the counter preparation suitable for self-care/purchase if appropriate

13.02.01 ZeroAQS ® 

Least greasy option
Use as a soap substitute in eczema, not emollient

Over the counter preparation suitable for self-care/purchase if appropriate

A5.13 ZeroAQS cream 

Preferred local option

Emollient cream that occludes and moisturises the skin.
Type of wound product is suitable for
For external application for use as an emollient and as a skin cleanser/soap substitute
in the management for dry skin conditions.
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Dermatology approved
Does not contain sodium lauryl sulphate (SLS)

A5.13 Zerobase 

Preferred local option

Emollient cream containing liquid paraffin, to moisturise dry or chapped skin
Type of wound product is suitable for
Symptomatic treatment of dry or chapped skin
Can be used as a pre bathing emollient for dry skin to alleviate drying effects
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Dermatology approved

13.02.01 Zerobase® 

Least greasy

Preferred alternative to Diprobase

A5.13 Zerocream 

Preferred local option

Emollient cream containing liquid paraffin and soft white paraffin, to moisturise dry skin
Type of wound product is suitable for
Symptomatic treatment of flaking, dry skin, sunburn, dry eczema and dry cases of
psoriasis
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Dermatology approved

13.02.01 Zerocream® 

More greasy

Preferred alternative to E45 cream

13.02.01 Zeroderm Ointment 

CCG preffered alternative to Epaderm and Hydromol

A5.13 Zeroderm ointment 

Preferred local option

Emollient ointment containing liquid paraffin and white soft paraffin to assist the skin in retaining moisture
Type of wound product is suitable for
For use on all dry skin conditions including eczema and psoriasis
Can be used as a soap substitute/skin cleanser
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Treatment of dry skin conditions. Dermatology approved
Free from fragrance and colours, sodium lauryl sulphate, additives and preservatives

A5.13 Zeroguent 

Preferred local option

Rich emollient cream containing light liquid paraffin, white soft paraffin and soya bean oil
To assist the skin in retaining moisture
Type of wound product is suitable for
For use as a barrier and moisturiser for symptomatic treatment of dermatitis, ichthyosis, eczema and psoriasis
Can be used as a pre bathing emollient for dry skin to alleviate drying effects
Frequency of use
Daily or more frequently if required
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Allergy or hypersensitivity to any of the ingredients
Rationale for inclusion in formulary
Dermatology approved

13.02.01 Zeroguent® 

More greasy

Preferred alternative to Unguentum M

19.05 Zetuvit®E   Absorbent cellulose pad with fluid repellent backing
*only sterile to be used for wound care*

Type of wound product is suitable for
Moderate exuding wounds . Secondary dressing.
Available in non sterile and sterile.

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
Usually 1-2 days or when wet. If using daily consider Zetuvit® Plus

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity
Do not cut or tear

Rationale for inclusion in formulary
Required for absorbency, for moderately exuding wounds
Step down from Zetuvit® Plus
19.05 Zetuvit®Plus  Super absorbent dressing

Type of wound product is suitable for
Moderate to heavily exuding acute and chronic wounds. Secondary dressing only

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
1-3 days, if changing daily, review if needs more highly absorbent dressing, if lasting 7
days step down to Zetuvit®E

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use if sensitivity to dressing or components
Do not cut or tear

Rationale for inclusion in formulary
Moderate to heavily exuding wounds, higher absorbency than Zetuvit®E. Cost effective.
A5.01.02 Zetuvit® E  sterile: 10x10cm, 10x20cm, 20x20cm, 20x40cm non sterile: 10x10cm, 10x20cm, 20x20cm, 20x40cm

Preferred local option

Absorbent cellulose pad with fluid repellent backing
*Only STERILE to be used for wound care*

Type of wound product is suitable for
Moderate exuding wounds . Secondary dressing.
Available in non sterile and sterile.

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
Usually 1-2 days or when wet. If using daily consider Zetuvit® Plus

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Known product or component sensitivity
Do not cut or tear

Rationale for inclusion in formulary
Required for absorbency, for moderately exuding wounds
Step down from Zetuvit® Plus

A5.01.02 Zetuvit® Plus 

Preferred local option

Super absorbent dressing

Type of wound product is suitable for
Moderate to heavily exuding acute and chronic wounds. Secondary dressing only

Duration dressing remains on wound before changing
1-7 days

Frequency of dressing change
1-3 days, if changing daily, review if needs more highly absorbent dressing, if lasting 7
days step down to Zetuvit®E

Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Do not use if sensitivity to dressing or components
Do not cut or tear

Rationale for inclusion in formulary
Moderate to heavily exuding wounds, higher absorbency than Zetuvit®E. Cost effective.

05.03.01 Zidovudine Retrovir®
05.03.01 Zidovudine 
05.03.01 Zidovudine and Lamivudine 
13.14.06 Zinc & salicylic acid paste (Lassar’s paste) half-strength 
13.02.02 Zinc and Caster Oil Ointment BP 

Over the counter preparation suitable for self-care/purchase if appropriate

A5.15 Zinc and castor oil ointment 

Barrier cream
Type of wound product is suitable for
For relief of the symptoms of nappy rash and as a protective water resistant cream for
dry, chapped skin
Frequency of use
As required, up to four times daily or at each nappy change.
Caution/contraindications (when not to use the dressing, patient groups to avoid etc.)
Not to be used on adults in conjunction with containment products for incontinence due to the inclusion of peanut oil in the ingredients, which will repel urine/faeces back onto the skin.
Any allergy to the listed ingredients
May mask x-ray images
Rationale for inclusion in formulary
Dermatology approved

09.05.04 Zinc Sulphate Solvazinc®
06.06 Zoledronic acid 

Red - Aclasta

Red - Zometa

04.07.04.01 Zolmitriptan 
04.01.01 Zolpidem 
04.08.01 Zonisamide Zonegran®

On specialist advice with an ESCA

MHRA Advice
When prescribing for epilepsy the patient should be assessed  to make a clinical judgement if the same manufacturer's product/brand is necessary taking into account factors such as seizure frequency and treatment history. Also take into account patient/carer related factors such as their negative perceptions about alternative products and/or other issues related to the patient such as co-morbid autism, mental health issues or learning disability

04.01.01 Zopiclone 

Licensed for short-term use only (4 weeks).

04.02.01 Zuclopenthixol 

Supported by ESCA

04.02.02 Zuclopenthixol Decanoate 

The APC's view is that, on clinical grounds, the status of antipsychotic depot injections should be amber with a framework in place in Primary Care before transfer 

HOWEVER, until the commissioning arrangements have been agreed to allow safe transfer of patient care, the status will remain RED

06.04.01.01 Zumenon® 
NHS NEL