• Actrapid
• Humulin S
• Insuman Rapid

• Fiasp
• Fiasp FlexTouch
• Fiasp Penfill
• NovoRapid
• NovoRapid FlexPen
• NovoRapid FlexTouch
• NovoRapid Penfill
• Trurapi

• NovoRapid PumpCart

BRANDS

• Apidra
• Apidra SoloStar

BRANDS

• Humalog Junior KwikPen

• Levemir FlexPen
• Levemir InnoLet
• Levemir Penfill

• Abasaglar KwikPen
• Lantus
• Toujeo
• Toujeo DoubleStar

• Tresiba FlexTouch 200units/ml

  Type I Diabetes

 Type II Diabetes

• Tresiba FlexTouch 100units/ml
• Tresiba Penfill 100units/ml

• Humulin I
• Humulin I KwikPen
• Insulatard
• Insulatard InnoLet
• Insulatard Penfill
• Insuman Basal
• Insuman Basal SoloStar

BRANDS

• NovoMix 30 FlexPen
• NovoMix 30 Penfill

BRANDS

• Humalog Mix25
• Humalog Mix25 KwikPen
• Humalog Mix50
• Humalog Mix50 KwikPen

BRANDS

• Humulin M3
• Humulin M3 KwikPen

Insuman comb 25

Insuman comb 50

• Admelog
• Humalog 100units/ml
• Humalog KwikPen
• Lyumjev
• Lyumjev KwikPen
• Lyumjev Junior KwikPen

There are used primarily to protect any individuals administering insulin as a third party

• AllStar Pro hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-80 units
• Autopen
• Autopen 24 hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-21 units
• Autopen 24 hypodermic insulin injection pen reusable for 3ml cartridge 2 unit dial up / range 2-42 units
• Autopen Classic hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-21 units
• Autopen Classic hypodermic insulin injection pen reusable for 3ml cartridge 2 unit dial up / range 2-42 units
• HumaPen Ergo
• HumaPen Luxura
• HumaPen Luxura HD hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 1-30 units
• HumaPen Savvio hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-60 units
• JuniorSTAR hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 1-30 units
• NovoPen
• NovoPen 5 hypodermic insulin injection pen reusable for 3ml cartridge 1 unit dial up / range 1-60 units
• NovoPen Echo hypodermic insulin injection pen reusable for 3ml cartridge 0.5 unit dial up / range 0.5-30 units
• OptiPen Pro 1
• mhi-500

BRANDS

• Injex 10ml vial adaptor pack
• Injex 4 monthly refill pack
• Injex ampoule pack
• Injex starter set
• InsuJet 10ml vial adaptor pack 5 pieces
• InsuJet 3ml cartridge adaptor pack 5 pieces
• InsuJet nozzle pack 5 pieces
• InsuJet starter set

• Tablets
• Modified Release Tablets

Check OptimiseRx for most cost effective brand

Patients with swallowing difficulties

For patients with swallowing difficulties only.

Tablets more cost effective.

Check Optimise Rx for most cost effective brand 

A variety of combinations tablets (dual therapies) of oral diabetes medication can be prescribed and are available in the Drug Tariff.   

Overall, they may improve compliance in patients, however some combinations would then not allow the flexibility in dosing that is required for diabetes management and in some cases increase the tablet burden. There are specific sick-day rules related to stopping certain medication which would be further complicated where they are not prescribed in their separate formulations.

Furthermore, for the overall health economy not all combination therapies are cost-effective and this will be increasingly so as the patents expire over the near future.

There are some combination therapies that are not recommended in the oral guidance and clinicians are guided to review and discuss these with patients as part of shared -care decision making. 

There are complexities also around the lack of licensing of dual therapies in specific cohorts of patients, related to prescribing for the indication of heart failure or renal disease, making this a complex area for prescribing in primary care. 

A variety of combinations tablets (dual therapies)
of oral diabetes medication can be prescribed and
are available in the Drug Tariff.

Overall, they may improve compliance in patients,
however some combinations would then not allow
the flexibility in dosing that is required for diabetes
management and in some cases increase the
tablet burden. There are specific sick-day rules
related to stopping certain medication which
would be further complicated where they are not
prescribed in their separate formulations.

Furthermore, for the overall health economy not
all combination therapies are cost-effective and
this will be increasingly so as the patents expire
over the near future. There are some combination
therapies that are not recommended in the oral
guidance and clinicians are guided to review and
discuss these with patients as part of shared -care
decision making.

There are complexities also around the lack of
licensing of dual therapies in specific cohorts of
patients, related to prescribing for the indication of
heart failure or renal disease, making this a
complex area for prescribing in primary care

A variety of combinations tablets (dual therapies)
of oral diabetes medication can be prescribed and
are available in the Drug Tariff.

Overall, they may improve compliance in patients,
however some combinations would then not allow
the flexibility in dosing that is required for diabetes
management and in some cases increase the
tablet burden. There are specific sick-day rules
related to stopping certain medication which
would be further complicated where they are not
prescribed in their separate formulations.

Furthermore, for the overall health economy not
all combination therapies are cost-effective and
this will be increasingly so as the patents expire
over the near future. There are some combination
therapies that are not recommended in the oral
guidance and clinicians are guided to review and
discuss these with patients as part of shared -care
decision making.

There are complexities also around the lack of
licensing of dual therapies in specific cohorts of
patients, related to prescribing for the indication of
heart failure or renal disease, making this a
complex area for prescribing in primary care

In line with NICE No significant clinical benefit when used in combination with Insulin – avoid using together 

In line with NICE
Linagliptin has no significant clinical benefit or renoprotective effect in patients with CKD.

Sitagliptin should be used first line at the appropriate renal dose
where a DPP4 inhibitor is indicated

No significant clinical benefit when used in combination
with Insulin – avoid using together

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

•  prolonged-release suspension for injection

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

• Injection
• For weight loss/ obesity
• Use according to NICE guidance

The use of Liraglutide for this indication is restricted to prescribing in secondary care by a specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Saxenda ^®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

Use according to NICE guidance

For the treatment of type 2 diabetes ONLY

THIS IS FOR DIABETES ONLY.  Prescribe by brand (Victoza^®) to avoid patients inadvertently receiving a different product licensed for obesity.

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

Rybelsus is a tablet for once-daily oral use but has special administration directions:

• It must be taken on an empty stomach at any time of the day.

• Patients are required to wait at least 30 minutes before eating/drinking or taking other oral medicinal products. Waiting less than 30 minutes decreases absorption.

• It should be swallowed whole with a sip of water (up to half a glass of water equivalent to 120 ml).

PLEASE PRESCRIBE BY BRAND - NICE Guidance on prescribing

Semaglutide is a biological medicine. Biological medicines must be prescribed and dispensed by brand name, see Biological medicines and Biosimilar medicines, under Guidance on Prescribing; manufacturer advises to record the brand name and batch number after each administration.

• Injection
• For weight loss/ obesity
• Use according to NICE TA 875 https://www.nice.org.uk/guidance/ta875/resources/semaglutide-for-managing-overweight-and-obesity-pdf-82613674831813

The use of semaglutide for this indication is restricted to prescribing by commissioned clinics in secondary care by a consultant led specialist multidisciplinary Tier 3 weight management service with a commercial agreement in place.

Prescribe by brand (Wegovy^®) to avoid patients inadvertently receiving a different product licensed for type 2 diabetes.

For treating Type 2 diabetes  in line with NICE, and chronic kidney disease.

Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis) 

  for treating Type 2 diabetes and chronic kidney disease in line with NICE 

Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis)

 Treatment of all grades of symptomatic heart failure 

SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

  For treating type 2 diabetes
Do not use SGLT2-inhibitors in patients with T1DM, regardless of CKD and/or heart failure status due to risk of DKA (diabetic ketoacidosis)

 treatment of all grades of symptomatic heart failure

SGLT2 inhibitors: updated advice on the risk of diabetic ketoacidosis

MHRA: SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)

In line with NICE

Do not use SGLT2-inhibitors in patients with T1DM,
regardless of CKD and/or heart failure status due to risk
of DKA (diabetic ketoacidosis)

• Axsain
• Zacin

• Qutenza - PAIN TEAM ONLY

Prescribe generically as 30mg & 60mg.

90 and 120mg not cost-effective

• Dextrogel 

In line with NHSE criteria, see annex A in the following link: https://www.blackcountryformulary.nhs.uk/docs/files/National-arrangements-for-funding-of-relevant-diabetes-patients-June-2020-Updated-final.pdf

 in Type I Diabetes

in Type II Diabetes in line with RMOC criteria

• FreeStyle Optium beta-ketone testing strips

• KetoSens testing strips

 in Primary Care

Secondary care to discuss with Pathology

  BRANDS-Use in line with local guidance

• CareSens PRO testing strips
• Contour Next testing strips
• Contour Plus testing strips
• Instant testing strips
• TEE2 testing strips
• WaveSense JAZZ Duo testing strips
• WaveSense JAZZ testing strips

   BRANDS

• Aviva testing strips
• FreeStyle Optium testing strips
• On Call Extra testing strips

For Paediatric use 

• BETALOC

Counselling: warn patient to tell doctor immediately if sore throat, mouth ulcers, bruising, fever, malaise or non-specific illness develops

Hospital use only.

• SODIUM SUCCINATE
• SODIUM PHOSPHATE

2nd line to patches 

https://pcwhf.co.uk/wp-content/uploads/2021/02/Prescribing-HRT-3.pdf 

Pessary 

• Vagifem
• Vagirux

 2nd line to Evorel Sequi®

BRANDS

• Elleste-Duet
• Prempak-C

Fertility use only

Progynova® 1mg and 2mg tablets

Suitable for self injection in patients who have had appropriate tranining

    BRANDS

• Cyclogest pessary 
• Lutigest pessary 

BRANDS

• Androcur

Treatment of hyponatraemia resulting from inappropriate secretion of antidiuretic hormone, if fluid restriction alone does not restore sodium concentration or is not tolerable

 Paediatric Nocturnal enuresis

 Diabetes Insipidus

Diabetes Insipidus

Primary Nocturnal enureis -Paediatrics

HRF - Red

Powder For - Red

HUMAN MENOPAUSAL GONADOTROPHINS - Red

HUMAN MENOPAUSAL GONADOTROPHINS / Menogon - Red

Olatuton - Red

Sandostatin - Red

Sandostatin LAR - Red

Glypressin - Red

   BRANDS

• Synacthen
• Synacthen Depot

Argipressin - Red

Pitressin - Red

CALCITONIN (SALMON)/SALCATONIN - Red

CALCITONIN SALMON/ CALCITONIN - Red

Dudley

Sandwell

ESCA Sandwell only

Walsall

Wolverhampton 

Evenity - Red

Dudley 

Sandwell

ESCA- Sandwell

Walsall

Wolverhampton

Red - Forsteo

Red - Movymia

Red - Terrosa

Red - Aclasta

Red - Zometa

Injection

Nasal spray

For hospital use only

In line with NICE

Dudley 

Sandwell

ESCA-Denosumab-Sandwell only

Walsall

Wolverhampton 

 with RiCaD 

Wolverhampton only

Amber Recommended - Cabaser

Amber Recommended - Dostinex

Off label use for hereditary angiodema

Amber Initiation - Prostap 3 DCS

Amber Initiation - Prostap SR DCS

• TABLETS
• ORAL SOLUTION

  BRANDS

•  Zodalex 
•  Zodalex LA